• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Hov-1237

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Tubulin alpha chain
Ensembl Gene: HORVU2Hr1G037550
Ensembl Protein: HORVU2Hr1G037550.3
Organism: Hordeum vulgare
Taxa ID: 112509
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

▼ SEQUENCE

Protein Sequence (FASTA)
1     EGDHQHPHRP  GRDPGRQRLL  GALLPRARHQ  SGWHHAQVHT  DTTVGVAHDA  FNTFFSETGA  60
61    GKHVPRAIFV  DLEPTVIDEV  RTGAYRQLFH  PEQLISGKED  AANNFARGHY  TVGKEIVDLC  120
121   LDRVRKLADN  CTGLQGFLVF  NAVGGGTGSG  LGSLLLERLS  VDYGKKSKLG  FTIYPSPQVS  180
181   TAVVEPYNSV  LSTHSLLEHT  DVAVLLDNEA  IYDICRRSLD  IERPTYTNLN  RLISQIISSL  240
241   TTSLRFDGAI  NVDVTEFQTN  LVPYPRIHFM  LSSYAPVISA  EKAYHEQLSV  PEITNAVFEP  300
301   SSMMAKCDPR  HGKYMACCLM  YRGDVVPKDV  NAAVATIKTK  RTVQFVDWCP  TGFKCGINYQ  360
361   PPSVVPGGDL  AKVQRAVCMI  SNNTAVAEVF  SRIDHKFDLM  YAKRAFVHWY  VGEGMEEGEF  420
421   SEAREDLAAL  EKDYEEVGAE  GADDEGDEGD  DY  452
Nucleotide CDS Sequence (FASTA)
1     ATGAGGGAGA  TCATCAGCAT  CCACATCGGC  CAGGCCGGGA  TCCAGGTCGG  CAACGCTTGC  60
61    TGGGAGCTCT  ACTGCCTCGA  GCACGGCATC  AATCAGGATG  GCACCATGCC  CAGTGACACC  120
121   ACGGTTGGGG  TTGCACACGA  TGCGTTCAAC  ACGTTCTTCA  GTGAGACCGG  TGCGGGCAAG  180
181   CACGTGCCGA  GGGCCATCTT  CGTCGACCTT  GAGCCCACTG  TCATCGATGA  GGTGCGCACC  240
241   GGTGCCTACC  GCCAGCTCTT  CCACCCGGAG  CAGCTCATCT  CTGGGAAGGA  GGATGCCGCC  300
301   AACAACTTCG  CCCGTGGCCA  CTACACTGTT  GGAAAGGAGA  TCGTAGATCT  ATGTCTGGAT  360
361   CGTGTACGCA  AATTGGCAGA  CAATTGCACC  GGGCTGCAGG  GATTCTTGGT  GTTCAATGCT  420
421   GTCGGTGGTG  GAACTGGATC  AGGACTGGGT  TCTCTGTTGT  TGGAGCGCCT  CTCGGTTGAT  480
481   TATGGCAAGA  AATCTAAGCT  TGGATTCACC  ATTTACCCTT  CCCCACAGGT  CTCAACAGCT  540
541   GTTGTAGAAC  CATACAACAG  TGTCCTCTCC  ACTCACTCTT  TGCTTGAGCA  CACCGACGTT  600
601   GCGGTCCTCC  TAGATAACGA  GGCTATCTAT  GACATATGCC  GGAGGTCTCT  TGACATTGAG  660
661   AGGCCAACCT  ACACCAACTT  GAACAGGCTG  ATATCACAGA  TCATATCTTC  TCTTACCACC  720
721   TCCCTGAGGT  TTGATGGTGC  CATCAATGTG  GATGTCACAG  AGTTCCAGAC  CAACCTTGTC  780
781   CCTTACCCAC  GTATCCATTT  CATGCTTTCG  TCGTATGCCC  CTGTTATCTC  TGCCGAGAAG  840
841   GCTTACCATG  AGCAGCTCTC  TGTGCCTGAA  ATCACCAATG  CTGTCTTTGA  GCCCTCAAGC  900
901   ATGATGGCCA  AGTGTGACCC  TAGGCATGGA  AAATATATGG  CCTGCTGCTT  GATGTACCGT  960
961   GGTGATGTTG  TTCCCAAGGA  TGTCAATGCC  GCGGTAGCAA  CCATCAAAAC  CAAGAGAACT  1020
1021  GTCCAGTTCG  TCGACTGGTG  CCCTACCGGG  TTCAAGTGTG  GCATCAACTA  CCAGCCACCT  1080
1081  TCCGTCGTCC  CCGGAGGTGA  CCTGGCAAAG  GTTCAGCGCG  CCGTGTGCAT  GATCAGCAAC  1140
1141  AACACCGCTG  TCGCCGAAGT  GTTCTCGCGC  ATCGACCACA  AGTTCGACTT  GATGTACGCC  1200
1201  AAGCGTGCGT  TCGTGCACTG  GTACGTCGGC  GAGGGAATGG  AGGAAGGTGA  GTTCTCGGAG  1260
1261  GCTCGTGAGG  ACTTGGCCGC  CCTCGAGAAG  GACTACGAGG  AAGTTGGCGC  CGAAGGCGCG  1320
1321  GACGACGAGG  GCGACGAGGG  CGATGACTAC  TAA  1353

▼ KEYWORD

ID
Family
Coiled coil
Complete proteome
Cytoplasm
Cytoskeleton
GTP-binding
Microtubule
Nucleotide-binding
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Cellular Component
Microtubule
Molecular Function
GTP binding
Molecular Function
GTPase activity
Molecular Function
Structural constituent of cytoskeleton
Biological Process
Microtubule-based process

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Bro-1856Brassica oleracea98.230.0 743
LLPS-Cus-1681Cucumis sativus97.970.0 741
LLPS-Brn-2360Brassica napus97.970.0 742
LLPS-Art-1313Arabidopsis thaliana97.970.0 742
LLPS-Php-2258Physcomitrella patens97.720.0 738
LLPS-Brr-0436Brassica rapa97.720.0 742
LLPS-Zem-2581Zea mays97.510.0 748
LLPS-Thc-1946Theobroma cacao97.470.0 740
LLPS-Glm-2655Glycine max97.220.0 737
LLPS-Gor-0113Gossypium raimondii97.220.0 741
LLPS-Pot-2021Populus trichocarpa96.710.0 736
LLPS-Coc-0984Corchorus capsularis96.70.0 731
LLPS-Prp-2001Prunus persica95.990.0 738
LLPS-Mae-2377Manihot esculenta95.70.0 731
LLPS-Hea-0156Helianthus annuus95.440.0 727
LLPS-Met-2581Medicago truncatula95.190.0 727
LLPS-Via-0218Vigna angularis94.680.0 724
LLPS-Vir-1071Vigna radiata93.730.0 726
LLPS-Amt-0703Amborella trichopoda93.730.0 728
LLPS-Lep-0536Leersia perrieri93.480.0 724
LLPS-Sem-0429Selaginella moellendorffii93.480.0 724
LLPS-Viv-1837Vitis vinifera93.480.0 724
LLPS-Phv-0112Phaseolus vulgaris93.480.0 726
LLPS-Nia-2478Nicotiana attenuata93.480.0 721
LLPS-Sob-1031Sorghum bicolor93.480.0 724
LLPS-Sot-1554Solanum tuberosum93.230.0 719
LLPS-Sol-2173Solanum lycopersicum93.230.0 721
LLPS-Dac-0916Daucus carota93.230.0 723
LLPS-Orbr-2016Oryza brachyantha93.230.0 725
LLPS-Orgl-1631Oryza glumaepatula92.980.0 717
LLPS-Orb-2303Oryza barthii92.980.0 717
LLPS-Ori-2327Oryza indica92.980.0 717
LLPS-Orni-0878Oryza nivara92.980.0 717
LLPS-Orr-0647Oryza rufipogon92.980.0 717
LLPS-Orm-1731Oryza meridionalis92.980.0 717
LLPS-Org-2214Oryza glaberrima92.980.0 717
LLPS-Ors-1178Oryza sativa92.980.0 717
LLPS-Arl-1441Arabidopsis lyrata92.910.0 714
LLPS-Sei-0380Setaria italica92.910.0 712
LLPS-Tra-1941Triticum aestivum92.910.0 713
LLPS-Brd-0075Brachypodium distachyon92.730.0 721
LLPS-Tru-1941Triticum urartu92.730.0 720
LLPS-Orp-1555Oryza punctata92.730.0 717
LLPS-Osl-0496Ostreococcus lucimarinus91.730.0 720
LLPS-Chr-1284Chlamydomonas reinhardtii90.730.0 713
LLPS-Bot-0312Bos taurus84.210.0 670
LLPS-Scf-2328Scleropages formosus83.710.0 668
LLPS-Paa-2748Papio anubis83.710.0 666
LLPS-Mal-2039Mandrillus leucophaeus83.710.0 666
LLPS-Leo-3078Lepisosteus oculatus83.710.0 667
LLPS-Maf-0209Macaca fascicularis83.710.0 666
LLPS-Chs-0207Chlorocebus sabaeus83.710.0 667
LLPS-Fud-2337Fukomys damarensis83.710.0 668
LLPS-Asm-0148Astyanax mexicanus83.710.0 668
LLPS-Icp-1141Ictalurus punctatus83.710.0 668
LLPS-Gog-3093Gorilla gorilla83.710.0 666
LLPS-Mam-0805Macaca mulatta83.710.0 666
LLPS-Poa-3265Pongo abelii83.710.0 667
LLPS-Gaga-0784Gallus gallus83.710.0 667
LLPS-Hos-1672Homo sapiens83.710.0 667
LLPS-Dar-3733Danio rerio83.710.0 668
LLPS-Pat-0458Pan troglodytes83.710.0 666
LLPS-Lac-1000Latimeria chalumnae83.710.0 668
LLPS-Orc-3307Oryctolagus cuniculus83.710.0 667
LLPS-Dio-2079Dipodomys ordii83.460.0 667
LLPS-Xim-1672Xiphophorus maculatus83.460.0 665
LLPS-Drm-0758Drosophila melanogaster83.460.0 665
LLPS-Tut-0018Tursiops truncatus83.460.0 667
LLPS-Myl-1343Myotis lucifugus83.460.0 667
LLPS-Ran-1474Rattus norvegicus83.460.0 667
LLPS-Sus-3651Sus scrofa83.460.0 667
LLPS-Aon-0811Aotus nancymaae83.460.0 667
LLPS-Cii-0592Ciona intestinalis83.460.0 666
LLPS-Mum-2981Mus musculus83.460.0 667
LLPS-Ora-0959Ornithorhynchus anatinus83.460.0 667
LLPS-Caj-2133Callithrix jacchus83.460.0 667
LLPS-Caf-1216Canis familiaris83.460.0 667
LLPS-Ten-2970Tetraodon nigroviridis83.460.0 667
LLPS-Cap-3401Cavia porcellus83.460.0 667
LLPS-Anc-2036Anolis carolinensis83.460.0 667
LLPS-Cas-1839Carlito syrichta83.460.0 666
LLPS-Man-1838Macaca nemestrina83.460.0 665
LLPS-Meg-1613Meleagris gallopavo83.460.0 666
LLPS-Pap-4472Pan paniscus83.460.0 667
LLPS-Urm-3000Ursus maritimus83.460.0 667
LLPS-Fec-0466Felis catus83.460.0 667
LLPS-Mod-1950Monodelphis domestica83.460.0 667
LLPS-Scm-0904Scophthalmus maximus83.460.0 666
LLPS-Pes-2127Pelodiscus sinensis83.460.0 665
LLPS-Loa-3422Loxodonta africana83.250.0 662
LLPS-Aim-0544Ailuropoda melanoleuca83.210.0 665
LLPS-Mup-0654Mustela putorius furo83.210.0 665
LLPS-Ere-0436Erinaceus europaeus83.210.0 665
LLPS-Orl-0238Oryzias latipes83.210.0 665
LLPS-Cea-1318Cercocebus atys83.210.0 665
LLPS-Mea-1952Mesocricetus auratus83.210.0 664
LLPS-Eqc-0069Equus caballus83.210.0 665
LLPS-Nol-3118Nomascus leucogenys83.210.0 665
LLPS-Ict-2143Ictidomys tridecemlineatus83.210.0 666
LLPS-Anp-1080Anas platyrhynchos83.210.0 664
LLPS-Pof-3465Poecilia formosa83.210.0 665
LLPS-Fia-1806Ficedula albicollis83.210.0 664
LLPS-Otg-3152Otolemur garnettii83.210.0 665
LLPS-Tar-3942Takifugu rubripes82.960.0 664
LLPS-Ova-0174Ovis aries82.960.0 666
LLPS-Xet-0144Xenopus tropicalis82.960.0 663
LLPS-Sah-0275Sarcophilus harrisii82.710.0 666
LLPS-Cis-1540Ciona savignyi82.210.0 665