LLPS-Gog-0859
EEF1AKMT1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | EEF1A lysine methyltransferase 1; N(6)-adenine-specific DNA methyltransferase 2; Protein-lysine N-methyltransferase N6AMT2 |
| Gene Name: | EEF1AKMT1, N6AMT2 |
| Ensembl Gene: | ENSGGOG00000016930.3 |
| Ensembl Protein: | ENSGGOP00000016520.2 |
| Organism: | Gorilla gorilla |
| Taxa ID: | 9595 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule, Others | Predicted from orthologs | (View) |
▼ FUNCTION
| Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSGGOT00000016985.3 | ENSGGOP00000016520.2 |
| UniProt | G3RL82, G3RL82_GORGO | |
| GeneBank | CABD030087998 | |
| RefSeq | XM_004054231.2 | XP_004054279.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSDLEDDETP QLSAHALAAL QEFYAEQKQQ IEPGEDDKYN IGIIEENWQL SQFWYSQETA 60 61 LQLAQEAIAA VGEGGRIACV SAPSVYQKLR ELCRENFSIY IFEYDKRFAM YGEEFIFYDY 120 121 NNPLDLPERI AAHSFDIVIA DPPYLSEECL RKTSETIKYL TRGKILLCTG AIMEEQAAEL 180 181 LGVKMCTFVP RHTRNLANEF RCYVNYDSGL DCGI 214 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGAGTGATT TGGAAGATGA TGAGACACCC CAGCTTTCTG CCCATGCCTT AGCAGCTCTC 60 61 CAGGAATTTT ATGCTGAGCA AAAGCAACAA ATTGAGCCAG GCGAGGATGA TAAATATAAC 120 121 ATTGGAATAA TAGAAGAGAA TTGGCAACTG AGCCAGTTTT GGTATAGTCA GGAAACTGCT 180 181 CTGCAACTGG CACAGGAGGC AATTGCAGCT GTAGGAGAAG GTGGCAGAAT CGCATGTGTG 240 241 AGTGCCCCTA GTGTTTACCA GAAACTCAGA GAGCTGTGCA GAGAAAACTT TTCTATATAC 300 301 ATCTTTGAAT ATGACAAAAG ATTTGCCATG TATGGAGAGG AGTTTATTTT CTATGATTAC 360 361 AATAATCCAT TGGACTTACC CGAAAGAATT GCTGCACATA GTTTTGACAT CGTAATAGCA 420 421 GATCCTCCCT ATCTTTCGGA GGAATGTCTC AGAAAAACAT CGGAAACCAT CAAGTACCTG 480 481 ACGCGGGGCA AGATTCTGCT GTGCACAGGT GCCATCATGG AAGAACAGGC AGCAGAACTC 540 541 CTTGGAGTGA AGATGTGCAC GTTTGTTCCA AGACACACCC GGAACTTGGC AAATGAGTTT 600 601 CGCTGTTATG TGAATTATGA TTCTGGGCTG GACTGTGGGA TCTGA 645 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytoplasm | |
Molecular Function | Nucleic acid binding | |
Molecular Function | Protein-lysine N-methyltransferase activity |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-4257 | Homo sapiens | 99.53 | 1e-158 | 445 |
| LLPS-Pat-4246 | Pan troglodytes | 99.53 | 5e-158 | 443 |
| LLPS-Pap-4133 | Pan paniscus | 99.53 | 5e-158 | 443 |
| LLPS-Poa-3253 | Pongo abelii | 99.53 | 4e-158 | 443 |
| LLPS-Nol-4582 | Nomascus leucogenys | 97.66 | 1e-155 | 437 |
| LLPS-Man-1918 | Macaca nemestrina | 97.2 | 4e-155 | 436 |
| LLPS-Maf-2770 | Macaca fascicularis | 97.2 | 4e-155 | 436 |
| LLPS-Mam-4718 | Macaca mulatta | 96.73 | 5e-155 | 436 |
| LLPS-Cea-3848 | Cercocebus atys | 96.73 | 2e-154 | 434 |
| LLPS-Paa-3210 | Papio anubis | 96.73 | 1e-154 | 434 |
| LLPS-Rhb-0131 | Rhinopithecus bieti | 96.26 | 2e-153 | 431 |
| LLPS-Chs-0898 | Chlorocebus sabaeus | 96.26 | 7e-154 | 433 |
| LLPS-Mal-2017 | Mandrillus leucophaeus | 96.26 | 5e-153 | 431 |
| LLPS-Caj-3629 | Callithrix jacchus | 94.39 | 5e-152 | 428 |
| LLPS-Aon-2589 | Aotus nancymaae | 92.99 | 2e-149 | 421 |
| LLPS-Ict-4726 | Ictidomys tridecemlineatus | 88.63 | 1e-140 | 399 |
| LLPS-Otg-2759 | Otolemur garnettii | 88.32 | 7e-140 | 397 |
| LLPS-Aim-0410 | Ailuropoda melanoleuca | 86.73 | 3e-137 | 390 |
| LLPS-Dio-1357 | Dipodomys ordii | 85.8 | 2e-106 | 311 |
| LLPS-Urm-1425 | Ursus maritimus | 85.78 | 3e-135 | 385 |
| LLPS-Orc-1718 | Oryctolagus cuniculus | 85.51 | 8e-139 | 394 |
| LLPS-Caf-4484 | Canis familiaris | 84.83 | 1e-134 | 384 |
| LLPS-Ran-2656 | Rattus norvegicus | 83.96 | 1e-134 | 384 |
| LLPS-Mup-2981 | Mustela putorius furo | 83.89 | 5e-134 | 382 |
| LLPS-Tut-2109 | Tursiops truncatus | 83.89 | 8e-123 | 354 |
| LLPS-Mum-4118 | Mus musculus | 83.02 | 9e-135 | 385 |
| LLPS-Loa-4396 | Loxodonta africana | 82.55 | 1e-131 | 376 |
| LLPS-Mea-3066 | Mesocricetus auratus | 82.55 | 8e-133 | 379 |
| LLPS-Cas-2131 | Carlito syrichta | 82.24 | 8e-131 | 374 |
| LLPS-Fud-3682 | Fukomys damarensis | 80.28 | 3e-127 | 365 |
| LLPS-Myl-3419 | Myotis lucifugus | 80.09 | 5e-127 | 365 |
| LLPS-Sah-2550 | Sarcophilus harrisii | 79.9 | 1e-121 | 352 |
| LLPS-Fec-2261 | Felis catus | 79.62 | 2e-119 | 345 |
| LLPS-Cap-2967 | Cavia porcellus | 79.62 | 1e-124 | 358 |
| LLPS-Ova-4383 | Ovis aries | 78.4 | 3e-120 | 348 |
| LLPS-Mod-2467 | Monodelphis domestica | 77.67 | 1e-123 | 357 |
| LLPS-Ora-2090 | Ornithorhynchus anatinus | 76.64 | 9e-124 | 356 |
| LLPS-Eqc-2769 | Equus caballus | 76.33 | 3e-133 | 381 |
| LLPS-Ere-0042 | Erinaceus europaeus | 75.21 | 3e-63 | 199 |
| LLPS-Lac-3905 | Latimeria chalumnae | 74.16 | 2e-115 | 335 |
| LLPS-Sus-3733 | Sus scrofa | 73.46 | 2e-116 | 338 |
| LLPS-Gaga-1873 | Gallus gallus | 73.17 | 1e-107 | 315 |
| LLPS-Pes-3420 | Pelodiscus sinensis | 72.95 | 3e-109 | 320 |
| LLPS-Anp-2809 | Anas platyrhynchos | 72.82 | 3e-108 | 317 |
| LLPS-Fia-0189 | Ficedula albicollis | 72.38 | 2e-110 | 322 |
| LLPS-Meg-2782 | Meleagris gallopavo | 72.33 | 4e-106 | 311 |
| LLPS-Tag-3384 | Taeniopygia guttata | 71.9 | 1e-109 | 320 |
| LLPS-Anc-3944 | Anolis carolinensis | 70.09 | 4e-107 | 314 |
| LLPS-Dar-2933 | Danio rerio | 66.46 | 3e-76 | 234 |
| LLPS-Xet-3368 | Xenopus tropicalis | 66.36 | 1e-103 | 305 |
| LLPS-Bot-3432 | Bos taurus | 65.75 | 2e-93 | 280 |
| LLPS-Leo-2046 | Lepisosteus oculatus | 63.98 | 4e-99 | 293 |
| LLPS-Asm-1914 | Astyanax mexicanus | 62.56 | 3e-94 | 281 |
| LLPS-Orn-1919 | Oreochromis niloticus | 62.33 | 2e-97 | 290 |
| LLPS-Icp-1748 | Ictalurus punctatus | 61.9 | 2e-85 | 259 |
| LLPS-Scf-1706 | Scleropages formosus | 61.61 | 4e-95 | 283 |
| LLPS-Pof-3699 | Poecilia formosa | 61.19 | 2e-93 | 280 |
| LLPS-Xim-3613 | Xiphophorus maculatus | 60.83 | 3e-94 | 281 |
| LLPS-Orl-4005 | Oryzias latipes | 60.0 | 9e-91 | 273 |
| LLPS-Tar-0998 | Takifugu rubripes | 59.62 | 4e-90 | 271 |
| LLPS-Scm-0655 | Scophthalmus maximus | 58.96 | 2e-86 | 263 |
| LLPS-Ten-2241 | Tetraodon nigroviridis | 57.14 | 8e-86 | 260 |
| LLPS-Gaa-0224 | Gasterosteus aculeatus | 55.05 | 1e-68 | 216 |
| LLPS-Prp-0474 | Prunus persica | 46.48 | 2e-58 | 191 |
| LLPS-Glm-1987 | Glycine max | 46.48 | 9e-63 | 201 |
| LLPS-Phv-0043 | Phaseolus vulgaris | 46.12 | 5e-60 | 194 |
| LLPS-Met-0910 | Medicago truncatula | 45.67 | 5e-63 | 202 |
| LLPS-Sot-2135 | Solanum tuberosum | 45.58 | 2e-58 | 191 |
| LLPS-Via-1874 | Vigna angularis | 45.15 | 1e-58 | 191 |
| LLPS-Cae-1700 | Caenorhabditis elegans | 45.13 | 4e-57 | 186 |
| LLPS-Nia-0763 | Nicotiana attenuata | 44.39 | 2e-58 | 191 |
| LLPS-Viv-1152 | Vitis vinifera | 44.39 | 7e-60 | 194 |
| LLPS-Hea-2706 | Helianthus annuus | 43.98 | 6e-60 | 194 |
| LLPS-Cus-1892 | Cucumis sativus | 43.93 | 3e-57 | 187 |
| LLPS-Thc-2505 | Theobroma cacao | 43.72 | 2e-58 | 191 |
| LLPS-Mae-0882 | Manihot esculenta | 43.58 | 1e-57 | 189 |
| LLPS-Dac-0817 | Daucus carota | 43.4 | 1e-51 | 182 |
| LLPS-Arl-0036 | Arabidopsis lyrata | 43.3 | 1e-58 | 191 |
| LLPS-Sem-2110 | Selaginella moellendorffii | 43.26 | 8e-54 | 178 |
| LLPS-Brr-1999 | Brassica rapa | 42.99 | 4e-55 | 182 |
| LLPS-Zem-2414 | Zea mays | 42.99 | 5e-54 | 179 |
| LLPS-Ors-1492 | Oryza sativa | 42.92 | 1e-45 | 157 |
| LLPS-Org-2064 | Oryza glaberrima | 42.92 | 1e-45 | 157 |
| LLPS-Orr-1262 | Oryza rufipogon | 42.92 | 1e-45 | 157 |
| LLPS-Orni-1247 | Oryza nivara | 42.92 | 1e-45 | 157 |
| LLPS-Ori-1241 | Oryza indica | 42.92 | 1e-45 | 157 |
| LLPS-Art-2362 | Arabidopsis thaliana | 42.86 | 1e-56 | 186 |
| LLPS-Mua-2282 | Musa acuminata | 42.73 | 4e-50 | 169 |
| LLPS-Coc-0087 | Corchorus capsularis | 42.54 | 2e-59 | 193 |
| LLPS-Brn-0895 | Brassica napus | 42.53 | 1e-54 | 181 |
| LLPS-Tra-0899 | Triticum aestivum | 42.45 | 2e-46 | 160 |
| LLPS-Orbr-1099 | Oryza brachyantha | 42.25 | 3e-50 | 169 |
| LLPS-Sob-1059 | Sorghum bicolor | 42.06 | 2e-52 | 176 |
| LLPS-Bro-2014 | Brassica oleracea | 42.06 | 6e-49 | 174 |
| LLPS-Sol-2356 | Solanum lycopersicum | 41.95 | 9e-51 | 179 |
| LLPS-Lep-0438 | Leersia perrieri | 41.71 | 6e-49 | 166 |
| LLPS-Pot-1645 | Populus trichocarpa | 41.31 | 2e-52 | 176 |
| LLPS-Orm-1949 | Oryza meridionalis | 40.66 | 3e-39 | 141 |
| LLPS-Sei-0317 | Setaria italica | 40.62 | 2e-53 | 178 |
| LLPS-Trv-1030 | Trichoderma virens | 40.43 | 1e-43 | 152 |
| LLPS-Amt-0685 | Amborella trichopoda | 40.28 | 3e-45 | 164 |
| LLPS-Orp-1657 | Oryza punctata | 40.27 | 4e-43 | 151 |
| LLPS-Hov-0739 | Hordeum vulgare | 40.19 | 1e-46 | 161 |
| LLPS-Brd-1988 | Brachypodium distachyon | 40.19 | 4e-44 | 154 |
| LLPS-Php-0967 | Physcomitrella patens | 39.38 | 4e-49 | 167 |
| LLPS-Dos-0784 | Dothistroma septosporum | 39.15 | 4e-43 | 151 |
| LLPS-Lem-0143 | Leptosphaeria maculans | 39.13 | 7e-45 | 155 |
| LLPS-Drm-2198 | Drosophila melanogaster | 38.74 | 5e-40 | 142 |
| LLPS-Coo-0937 | Colletotrichum orbiculare | 38.43 | 3e-42 | 149 |
| LLPS-Cog-0691 | Colletotrichum gloeosporioides | 37.99 | 2e-42 | 155 |
| LLPS-Yal-1075 | Yarrowia lipolytica | 37.93 | 2e-40 | 144 |
| LLPS-Sac-0387 | Saccharomyces cerevisiae | 37.83 | 9e-40 | 142 |
| LLPS-Phn-0574 | Phaeosphaeria nodorum | 37.5 | 2e-44 | 154 |
| LLPS-Ved-0996 | Verticillium dahliae | 37.45 | 3e-42 | 149 |
| LLPS-Nec-1275 | Neurospora crassa | 37.39 | 5e-44 | 154 |
| LLPS-Gor-0387 | Gossypium raimondii | 37.3 | 7e-48 | 164 |
| LLPS-Pytr-0945 | Pyrenophora triticirepentis | 37.12 | 4e-39 | 140 |
| LLPS-Zyt-1300 | Zymoseptoria tritici | 36.56 | 3e-40 | 143 |
| LLPS-Mao-1225 | Magnaporthe oryzae | 35.96 | 6e-37 | 135 |
| LLPS-Orb-2016 | Oryza barthii | 35.92 | 4e-31 | 119 |
| LLPS-Gag-0833 | Gaeumannomyces graminis | 35.42 | 5e-40 | 144 |
| LLPS-Blg-0816 | Blumeria graminis | 34.71 | 2e-41 | 147 |
| LLPS-Cogr-1168 | Colletotrichum graminicola | 34.35 | 3e-36 | 133 |
| LLPS-Pyt-1294 | Pyrenophora teres | 34.04 | 1e-30 | 118 |
| LLPS-Map-1330 | Magnaporthe poae | 33.9 | 1e-37 | 137 |
| LLPS-Asg-1172 | Ashbya gossypii | 33.86 | 6e-36 | 132 |
| LLPS-Tum-1431 | Tuber melanosporum | 33.86 | 1e-35 | 132 |
| LLPS-Fuv-1182 | Fusarium verticillioides | 33.74 | 9e-35 | 129 |
| LLPS-Miv-0261 | Microbotryum violaceum | 33.33 | 1e-16 | 79.7 |
| LLPS-Fuo-0275 | Fusarium oxysporum | 32.78 | 4e-29 | 114 |
| LLPS-Scs-0591 | Sclerotinia sclerotiorum | 32.52 | 2e-13 | 68.9 |
| LLPS-Fus-1126 | Fusarium solani | 32.31 | 1e-30 | 119 |
| LLPS-Usm-0112 | Ustilago maydis | 31.87 | 6e-18 | 84.3 |
| LLPS-Kop-0703 | Komagataella pastoris | 31.74 | 4e-28 | 112 |
| LLPS-Spr-1302 | Sporisorium reilianum | 28.26 | 1e-14 | 75.1 |
| LLPS-Chr-1725 | Chlamydomonas reinhardtii | 25.0 | 6e-10 | 60.1 |