LLPS-Dar-2933
eef1akmt1
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | EEF1A lysine methyltransferase 1; N(6)-adenine-specific DNA methyltransferase 2; Protein-lysine N-methyltransferase n6amt2 |
| Gene Name: | eef1akmt1, n6amt2, zgc:77010 |
| Ensembl Gene: | ENSDARG00000040584.7 |
| Ensembl Protein: | ENSDARP00000059401.5 |
| Organism: | Danio rerio |
| Taxa ID: | 7955 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule, Others | Predicted from orthologs | (View) |
▼ FUNCTION
| Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSDART00000059402.6 | ENSDARP00000059401.5 |
| Ensembl | ENSDART00000147619.3 | ENSDARP00000113386.1 |
| UniProt | Q6NYP8, EFMT1_DANRE | |
| GeneBank | BC066508 | AAH66508.1 |
| RefSeq | NM_207087.1 | NP_996970.1 |
| Entrez | 404619 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSQFWYSEET ASRLAEELLQ QAGEHGRIAC LSAPSVYQKL KQLESVRSEG VSAVLLEFDR 60 61 RFAAYGDEFV FYDYNNPLCL PEDLLPQSFD IVIADPPYLS EECLSKVTLT VKHLTKGKIL 120 121 LCTGAIMEEH AGKLLDLKMC SFLPKHNHNL ANEFRCYVNY ESRLLS 166 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGAGTCAGT TCTGGTACAG TGAAGAAACA GCCTCACGGT TAGCTGAGGA GCTCCTGCAG 60 61 CAGGCTGGAG AACATGGGAG GATCGCCTGC TTAAGTGCAC CGAGTGTGTA TCAGAAGCTG 120 121 AAGCAGCTGG AGTCTGTGCG GTCAGAAGGT GTGTCTGCTG TTTTGCTGGA GTTTGACAGG 180 181 CGTTTCGCAG CGTATGGAGA CGAGTTTGTT TTTTACGATT ACAACAATCC TCTGTGTCTG 240 241 CCTGAGGATC TGCTTCCTCA GAGCTTTGAC ATCGTCATCG CAGATCCACC GTACCTGTCA 300 301 GAGGAGTGTC TCAGCAAGGT CACACTCACC GTTAAACACC TCACAAAAGG CAAAATCCTG 360 361 CTCTGTACAG GAGCCATCAT GGAGGAGCAT GCTGGGAAAC TTCTGGATCT GAAGATGTGC 420 421 AGTTTTTTAC CAAAACACAA TCATAATCTT GCCAATGAGT TCCGCTGTTA TGTTAACTAT 480 481 GAATCAAGGC TTCTCTCATG A 501 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytoplasm | |
Molecular Function | Methyltransferase activity | |
Molecular Function | Nucleic acid binding | |
Molecular Function | Protein-lysine N-methyltransferase activity | |
Biological Process | Peptidyl-lysine methylation |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Icp-1748 | Ictalurus punctatus | 83.64 | 3e-101 | 297 |
| LLPS-Asm-1914 | Astyanax mexicanus | 81.07 | 5e-98 | 289 |
| LLPS-Leo-2046 | Lepisosteus oculatus | 78.05 | 6e-88 | 263 |
| LLPS-Orn-1919 | Oreochromis niloticus | 74.7 | 2e-88 | 265 |
| LLPS-Xim-3613 | Xiphophorus maculatus | 72.12 | 4e-83 | 251 |
| LLPS-Scf-1706 | Scleropages formosus | 72.12 | 4e-82 | 248 |
| LLPS-Pof-3699 | Poecilia formosa | 71.52 | 9e-83 | 250 |
| LLPS-Scm-0655 | Scophthalmus maximus | 71.26 | 2e-81 | 249 |
| LLPS-Orl-4005 | Oryzias latipes | 70.91 | 1e-82 | 250 |
| LLPS-Fia-0189 | Ficedula albicollis | 70.12 | 5e-79 | 240 |
| LLPS-Meg-2782 | Meleagris gallopavo | 69.51 | 2e-78 | 239 |
| LLPS-Tag-3384 | Taeniopygia guttata | 69.51 | 1e-78 | 239 |
| LLPS-Ora-2090 | Ornithorhynchus anatinus | 68.9 | 3e-78 | 238 |
| LLPS-Anp-2809 | Anas platyrhynchos | 68.29 | 9e-79 | 240 |
| LLPS-Gaga-1873 | Gallus gallus | 68.29 | 3e-77 | 236 |
| LLPS-Sah-2550 | Sarcophilus harrisii | 68.07 | 2e-78 | 239 |
| LLPS-Tar-0998 | Takifugu rubripes | 68.07 | 4e-80 | 243 |
| LLPS-Rhb-0131 | Rhinopithecus bieti | 67.68 | 4e-78 | 238 |
| LLPS-Ict-4726 | Ictidomys tridecemlineatus | 67.68 | 2e-79 | 241 |
| LLPS-Mod-2467 | Monodelphis domestica | 67.47 | 9e-78 | 238 |
| LLPS-Maf-2770 | Macaca fascicularis | 67.07 | 2e-77 | 236 |
| LLPS-Cea-3848 | Cercocebus atys | 67.07 | 6e-77 | 235 |
| LLPS-Paa-3210 | Papio anubis | 67.07 | 2e-77 | 236 |
| LLPS-Mal-2017 | Mandrillus leucophaeus | 67.07 | 2e-77 | 236 |
| LLPS-Otg-2759 | Otolemur garnettii | 67.07 | 1e-75 | 232 |
| LLPS-Hos-4257 | Homo sapiens | 67.07 | 1e-76 | 234 |
| LLPS-Man-1918 | Macaca nemestrina | 67.07 | 2e-77 | 236 |
| LLPS-Loa-4396 | Loxodonta africana | 67.07 | 6e-77 | 235 |
| LLPS-Nol-4582 | Nomascus leucogenys | 67.07 | 4e-77 | 236 |
| LLPS-Poa-3253 | Pongo abelii | 67.07 | 4e-77 | 236 |
| LLPS-Gog-0859 | Gorilla gorilla | 66.46 | 3e-76 | 234 |
| LLPS-Chs-0898 | Chlorocebus sabaeus | 66.46 | 2e-76 | 234 |
| LLPS-Ran-2656 | Rattus norvegicus | 66.46 | 2e-78 | 239 |
| LLPS-Pat-4246 | Pan troglodytes | 66.46 | 2e-76 | 234 |
| LLPS-Pap-4133 | Pan paniscus | 66.46 | 2e-76 | 234 |
| LLPS-Lac-3905 | Latimeria chalumnae | 66.46 | 1e-76 | 234 |
| LLPS-Mam-4718 | Macaca mulatta | 66.46 | 4e-77 | 236 |
| LLPS-Ten-2241 | Tetraodon nigroviridis | 66.27 | 1e-76 | 234 |
| LLPS-Caj-3629 | Callithrix jacchus | 65.85 | 5e-76 | 233 |
| LLPS-Aim-0410 | Ailuropoda melanoleuca | 65.85 | 3e-76 | 233 |
| LLPS-Urm-1425 | Ursus maritimus | 65.85 | 3e-76 | 233 |
| LLPS-Cas-2131 | Carlito syrichta | 65.85 | 8e-78 | 238 |
| LLPS-Caf-4484 | Canis familiaris | 65.85 | 2e-76 | 234 |
| LLPS-Eqc-2769 | Equus caballus | 65.85 | 7e-76 | 233 |
| LLPS-Fud-3682 | Fukomys damarensis | 65.24 | 3e-76 | 233 |
| LLPS-Mum-4118 | Mus musculus | 65.24 | 1e-74 | 229 |
| LLPS-Mup-2981 | Mustela putorius furo | 65.24 | 4e-76 | 233 |
| LLPS-Tut-2109 | Tursiops truncatus | 65.24 | 2e-68 | 214 |
| LLPS-Pes-3420 | Pelodiscus sinensis | 65.24 | 6e-76 | 233 |
| LLPS-Ere-0042 | Erinaceus europaeus | 65.04 | 8e-53 | 170 |
| LLPS-Mea-3066 | Mesocricetus auratus | 64.63 | 2e-74 | 229 |
| LLPS-Aon-2589 | Aotus nancymaae | 64.63 | 2e-74 | 229 |
| LLPS-Myl-3419 | Myotis lucifugus | 64.63 | 4e-74 | 228 |
| LLPS-Ova-4383 | Ovis aries | 64.63 | 4e-74 | 228 |
| LLPS-Orc-1718 | Oryctolagus cuniculus | 64.63 | 4e-75 | 231 |
| LLPS-Cap-2967 | Cavia porcellus | 64.63 | 2e-76 | 234 |
| LLPS-Gaa-0224 | Gasterosteus aculeatus | 64.5 | 3e-69 | 216 |
| LLPS-Dio-1357 | Dipodomys ordii | 63.41 | 1e-51 | 169 |
| LLPS-Xet-3368 | Xenopus tropicalis | 63.35 | 6e-71 | 220 |
| LLPS-Anc-3944 | Anolis carolinensis | 62.8 | 1e-73 | 227 |
| LLPS-Fec-2261 | Felis catus | 62.5 | 1e-67 | 211 |
| LLPS-Sus-3733 | Sus scrofa | 62.2 | 1e-69 | 216 |
| LLPS-Bot-3432 | Bos taurus | 53.8 | 8e-55 | 179 |
| LLPS-Trv-1030 | Trichoderma virens | 45.93 | 1e-35 | 130 |
| LLPS-Met-0910 | Medicago truncatula | 45.61 | 2e-42 | 147 |
| LLPS-Prp-0474 | Prunus persica | 45.61 | 7e-42 | 146 |
| LLPS-Phv-0043 | Phaseolus vulgaris | 45.29 | 2e-41 | 144 |
| LLPS-Nec-1275 | Neurospora crassa | 45.25 | 2e-38 | 138 |
| LLPS-Glm-1987 | Glycine max | 45.18 | 6e-42 | 146 |
| LLPS-Orb-2016 | Oryza barthii | 45.04 | 6e-30 | 114 |
| LLPS-Sot-2135 | Solanum tuberosum | 44.97 | 8e-41 | 143 |
| LLPS-Cus-1892 | Cucumis sativus | 44.85 | 1e-40 | 143 |
| LLPS-Hea-2706 | Helianthus annuus | 44.71 | 5e-41 | 144 |
| LLPS-Via-1874 | Vigna angularis | 44.71 | 4e-41 | 144 |
| LLPS-Sem-2110 | Selaginella moellendorffii | 44.31 | 2e-40 | 141 |
| LLPS-Mao-1225 | Magnaporthe oryzae | 44.25 | 1e-32 | 122 |
| LLPS-Brd-1988 | Brachypodium distachyon | 44.05 | 1e-36 | 133 |
| LLPS-Dac-0817 | Daucus carota | 43.98 | 7e-36 | 136 |
| LLPS-Nia-0763 | Nicotiana attenuata | 43.98 | 2e-38 | 137 |
| LLPS-Art-2362 | Arabidopsis thaliana | 43.98 | 7e-38 | 135 |
| LLPS-Orni-1247 | Oryza nivara | 43.79 | 1e-35 | 130 |
| LLPS-Ori-1241 | Oryza indica | 43.79 | 1e-35 | 130 |
| LLPS-Tra-0899 | Triticum aestivum | 43.79 | 6e-37 | 133 |
| LLPS-Ors-1492 | Oryza sativa | 43.79 | 1e-35 | 130 |
| LLPS-Org-2064 | Oryza glaberrima | 43.79 | 1e-35 | 130 |
| LLPS-Orr-1262 | Oryza rufipogon | 43.79 | 1e-35 | 130 |
| LLPS-Dos-0784 | Dothistroma septosporum | 43.68 | 1e-32 | 122 |
| LLPS-Thc-2505 | Theobroma cacao | 43.64 | 7e-41 | 143 |
| LLPS-Mua-2282 | Musa acuminata | 43.45 | 3e-40 | 142 |
| LLPS-Coc-0087 | Corchorus capsularis | 43.03 | 2e-40 | 142 |
| LLPS-Coo-0937 | Colletotrichum orbiculare | 43.02 | 7e-36 | 130 |
| LLPS-Amt-0685 | Amborella trichopoda | 42.94 | 7e-36 | 135 |
| LLPS-Lep-0438 | Leersia perrieri | 42.86 | 9e-38 | 135 |
| LLPS-Brn-0895 | Brassica napus | 42.77 | 4e-37 | 134 |
| LLPS-Arl-0036 | Arabidopsis lyrata | 42.77 | 7e-39 | 138 |
| LLPS-Brr-1999 | Brassica rapa | 42.77 | 3e-37 | 134 |
| LLPS-Lem-0143 | Leptosphaeria maculans | 42.53 | 2e-34 | 126 |
| LLPS-Viv-1152 | Vitis vinifera | 42.51 | 2e-39 | 139 |
| LLPS-Cog-0691 | Colletotrichum gloeosporioides | 42.44 | 2e-36 | 137 |
| LLPS-Cae-1700 | Caenorhabditis elegans | 42.35 | 1e-41 | 145 |
| LLPS-Orbr-1099 | Oryza brachyantha | 42.35 | 2e-38 | 137 |
| LLPS-Sob-1059 | Sorghum bicolor | 42.35 | 1e-40 | 143 |
| LLPS-Phn-0574 | Phaeosphaeria nodorum | 42.29 | 7e-33 | 122 |
| LLPS-Mae-0882 | Manihot esculenta | 42.26 | 2e-39 | 140 |
| LLPS-Yal-1075 | Yarrowia lipolytica | 42.2 | 1e-34 | 127 |
| LLPS-Gag-0833 | Gaeumannomyces graminis | 42.13 | 8e-34 | 125 |
| LLPS-Zyt-1300 | Zymoseptoria tritici | 42.11 | 1e-34 | 127 |
| LLPS-Orm-1949 | Oryza meridionalis | 42.05 | 1e-34 | 127 |
| LLPS-Hov-0739 | Hordeum vulgare | 41.86 | 5e-39 | 139 |
| LLPS-Sei-0317 | Setaria italica | 41.76 | 1e-39 | 140 |
| LLPS-Zem-2414 | Zea mays | 41.76 | 4e-40 | 142 |
| LLPS-Bro-2014 | Brassica oleracea | 41.42 | 3e-34 | 131 |
| LLPS-Pot-1645 | Populus trichocarpa | 41.07 | 3e-35 | 130 |
| LLPS-Pytr-0945 | Pyrenophora triticirepentis | 40.59 | 6e-28 | 109 |
| LLPS-Map-1330 | Magnaporthe poae | 40.33 | 6e-34 | 125 |
| LLPS-Blg-0816 | Blumeria graminis | 40.33 | 1e-32 | 122 |
| LLPS-Fuv-1182 | Fusarium verticillioides | 40.24 | 3e-26 | 105 |
| LLPS-Asg-1172 | Ashbya gossypii | 40.11 | 3e-31 | 118 |
| LLPS-Orp-1657 | Oryza punctata | 39.78 | 6e-34 | 125 |
| LLPS-Sac-0387 | Saccharomyces cerevisiae | 39.55 | 5e-34 | 125 |
| LLPS-Fuo-0275 | Fusarium oxysporum | 39.52 | 2e-23 | 97.8 |
| LLPS-Fus-1126 | Fusarium solani | 39.18 | 2e-25 | 103 |
| LLPS-Sol-2356 | Solanum lycopersicum | 38.95 | 2e-33 | 129 |
| LLPS-Cogr-1168 | Colletotrichum graminicola | 38.86 | 1e-31 | 119 |
| LLPS-Php-0967 | Physcomitrella patens | 38.69 | 6e-35 | 128 |
| LLPS-Ved-0996 | Verticillium dahliae | 38.42 | 5e-31 | 118 |
| LLPS-Pyt-1294 | Pyrenophora teres | 36.78 | 3e-20 | 88.6 |
| LLPS-Drm-2198 | Drosophila melanogaster | 36.57 | 2e-29 | 113 |
| LLPS-Scs-0591 | Sclerotinia sclerotiorum | 35.24 | 5e-09 | 55.5 |
| LLPS-Kop-0703 | Komagataella pastoris | 35.12 | 1e-23 | 98.2 |
| LLPS-Tum-1431 | Tuber melanosporum | 34.02 | 5e-29 | 113 |
| LLPS-Gor-0387 | Gossypium raimondii | 33.52 | 5e-28 | 110 |
| LLPS-Usm-0112 | Ustilago maydis | 30.39 | 1e-14 | 73.6 |
| LLPS-Miv-0261 | Microbotryum violaceum | 29.65 | 6e-12 | 65.5 |
| LLPS-Chr-1725 | Chlamydomonas reinhardtii | 29.21 | 2e-12 | 66.2 |
| LLPS-Spr-1302 | Sporisorium reilianum | 28.42 | 6e-11 | 63.5 |