LLPS-Caf-4484
EEF1AKMT1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | EEF1A lysine methyltransferase 1; N(6)-adenine-specific DNA methyltransferase 2; Protein-lysine N-methyltransferase N6AMT2 |
| Gene Name: | EEF1AKMT1, N6AMT2 |
| Ensembl Gene: | ENSCAFG00000007231.3 |
| Ensembl Protein: | ENSCAFP00000010744.3 |
| Organism: | Canis familiaris |
| Taxa ID: | 9615 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule, Others | Predicted from orthologs | (View) |
▼ FUNCTION
| Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSCAFT00000011595.3 | ENSCAFP00000010744.3 |
| UniProt | E2R958, E2R958_CANLF | |
| GeneBank | AAEX03014275, AAEX03014274 | |
| RefSeq | XM_005635555.2, XM_005635556.2, XM_543173.4 | XP_005635612.1, XP_005635613.1, XP_543173.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSDSDDDDIP RLSSHTLAAL QEFYAEQKQQ SDPGRDDKYN IGIIEENWQL SQFWYSQETA 60 61 LHLAKEAIAA AGEHGRIACV STPSVYQKLR ALHREDFSVY IFEYDKRFAI YGEEFIFYDY 120 121 NNPLDLPEKI AARSFDIVIA DPPYLSKECL RKTSETIKYL TQGKILLCTG AVMEEEAAKL 180 181 LGVKMCKFIP KHTRTLGNEF RCYVNYDSGL DREI 214 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGAGTGACT CTGATGATGA CGATATCCCT CGGCTATCTT CCCACACATT AGCAGCCCTC 60 61 CAGGAATTTT ATGCTGAGCA GAAGCAACAA AGTGACCCTG GCAGGGATGA TAAATATAAC 120 121 ATTGGAATAA TAGAAGAGAA CTGGCAGCTG AGCCAGTTTT GGTACAGTCA GGAAACTGCC 180 181 TTGCACCTTG CGAAGGAAGC CATCGCAGCT GCTGGAGAGC ATGGCAGAAT AGCCTGTGTG 240 241 AGCACCCCCA GTGTTTACCA GAAACTGAGA GCCCTACACA GAGAAGACTT CTCTGTATAC 300 301 ATCTTTGAAT ATGACAAAAG ATTTGCCATA TACGGAGAGG AGTTTATCTT CTATGATTAT 360 361 AATAATCCAT TGGATTTACC AGAAAAAATT GCTGCACGTA GTTTTGACAT CGTAATAGCA 420 421 GATCCTCCCT ACCTTTCCAA GGAGTGTCTC CGAAAAACGT CAGAAACCAT CAAGTATCTG 480 481 ACTCAGGGCA AGATTCTGCT GTGCACAGGT GCCGTCATGG AAGAAGAGGC AGCAAAACTT 540 541 CTTGGCGTGA AGATGTGCAA ATTTATTCCA AAACACACCC GAACCTTGGG AAATGAGTTT 600 601 CGCTGTTATG TGAATTATGA TTCTGGGCTA GACCGGGAAA TCTAA 645 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytoplasm | |
Molecular Function | Nucleic acid binding | |
Molecular Function | Protein-lysine N-methyltransferase activity |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Urm-1425 | Ursus maritimus | 95.79 | 6e-139 | 395 |
| LLPS-Aim-0410 | Ailuropoda melanoleuca | 94.86 | 1e-137 | 392 |
| LLPS-Mup-2981 | Mustela putorius furo | 93.46 | 5e-138 | 393 |
| LLPS-Ict-4726 | Ictidomys tridecemlineatus | 87.68 | 4e-128 | 367 |
| LLPS-Caj-3629 | Callithrix jacchus | 87.2 | 1e-126 | 363 |
| LLPS-Tut-2109 | Tursiops truncatus | 86.92 | 1e-126 | 363 |
| LLPS-Loa-4396 | Loxodonta africana | 86.85 | 9e-127 | 364 |
| LLPS-Otg-2759 | Otolemur garnettii | 86.73 | 6e-125 | 359 |
| LLPS-Aon-2589 | Aotus nancymaae | 86.26 | 2e-124 | 358 |
| LLPS-Paa-3210 | Papio anubis | 85.78 | 7e-124 | 357 |
| LLPS-Nol-4582 | Nomascus leucogenys | 85.78 | 8e-125 | 359 |
| LLPS-Maf-2770 | Macaca fascicularis | 85.31 | 3e-123 | 355 |
| LLPS-Man-1918 | Macaca nemestrina | 85.31 | 3e-123 | 355 |
| LLPS-Gog-0859 | Gorilla gorilla | 84.83 | 8e-124 | 356 |
| LLPS-Cea-3848 | Cercocebus atys | 84.83 | 2e-123 | 355 |
| LLPS-Chs-0898 | Chlorocebus sabaeus | 84.83 | 4e-122 | 352 |
| LLPS-Mam-4718 | Macaca mulatta | 84.83 | 6e-123 | 354 |
| LLPS-Poa-3253 | Pongo abelii | 84.83 | 1e-123 | 356 |
| LLPS-Mal-2017 | Mandrillus leucophaeus | 84.36 | 9e-121 | 348 |
| LLPS-Orc-1718 | Oryctolagus cuniculus | 84.36 | 3e-123 | 355 |
| LLPS-Pap-4133 | Pan paniscus | 84.36 | 5e-123 | 354 |
| LLPS-Pat-4246 | Pan troglodytes | 84.36 | 5e-123 | 354 |
| LLPS-Hos-4257 | Homo sapiens | 84.36 | 1e-123 | 356 |
| LLPS-Rhb-0131 | Rhinopithecus bieti | 83.89 | 5e-122 | 352 |
| LLPS-Dio-1357 | Dipodomys ordii | 83.43 | 5e-93 | 277 |
| LLPS-Myl-3419 | Myotis lucifugus | 82.71 | 2e-120 | 348 |
| LLPS-Fec-2261 | Felis catus | 82.46 | 2e-121 | 350 |
| LLPS-Ran-2656 | Rattus norvegicus | 82.16 | 2e-121 | 351 |
| LLPS-Mum-4118 | Mus musculus | 81.22 | 9e-119 | 344 |
| LLPS-Eqc-2769 | Equus caballus | 80.41 | 1e-127 | 367 |
| LLPS-Mea-3066 | Mesocricetus auratus | 80.28 | 2e-119 | 346 |
| LLPS-Mod-2467 | Monodelphis domestica | 80.0 | 1e-117 | 342 |
| LLPS-Sah-2550 | Sarcophilus harrisii | 79.71 | 1e-112 | 328 |
| LLPS-Fud-3682 | Fukomys damarensis | 79.62 | 3e-113 | 330 |
| LLPS-Ova-4383 | Ovis aries | 79.07 | 2e-112 | 328 |
| LLPS-Cas-2131 | Carlito syrichta | 78.04 | 5e-116 | 337 |
| LLPS-Cap-2967 | Cavia porcellus | 77.25 | 5e-112 | 327 |
| LLPS-Tag-3384 | Taeniopygia guttata | 75.24 | 9e-104 | 305 |
| LLPS-Sus-3733 | Sus scrofa | 75.23 | 5e-111 | 324 |
| LLPS-Ere-0042 | Erinaceus europaeus | 75.21 | 4e-51 | 168 |
| LLPS-Fia-0189 | Ficedula albicollis | 74.76 | 2e-103 | 304 |
| LLPS-Gaga-1873 | Gallus gallus | 72.82 | 2e-98 | 292 |
| LLPS-Pes-3420 | Pelodiscus sinensis | 72.46 | 5e-99 | 294 |
| LLPS-Lac-3905 | Latimeria chalumnae | 72.43 | 2e-100 | 297 |
| LLPS-Anp-2809 | Anas platyrhynchos | 72.33 | 2e-98 | 292 |
| LLPS-Meg-2782 | Meleagris gallopavo | 72.33 | 2e-97 | 289 |
| LLPS-Ora-2090 | Ornithorhynchus anatinus | 72.3 | 1e-107 | 316 |
| LLPS-Anc-3944 | Anolis carolinensis | 71.5 | 2e-98 | 292 |
| LLPS-Xet-3368 | Xenopus tropicalis | 66.51 | 3e-96 | 286 |
| LLPS-Dar-2933 | Danio rerio | 65.85 | 2e-67 | 211 |
| LLPS-Leo-2046 | Lepisosteus oculatus | 64.62 | 9e-93 | 277 |
| LLPS-Bot-3432 | Bos taurus | 64.57 | 2e-84 | 257 |
| LLPS-Scf-1706 | Scleropages formosus | 63.03 | 2e-88 | 266 |
| LLPS-Asm-1914 | Astyanax mexicanus | 63.01 | 2e-88 | 266 |
| LLPS-Xim-3613 | Xiphophorus maculatus | 61.4 | 7e-85 | 258 |
| LLPS-Orn-1919 | Oreochromis niloticus | 61.4 | 5e-84 | 255 |
| LLPS-Pof-3699 | Poecilia formosa | 60.93 | 1e-83 | 254 |
| LLPS-Icp-1748 | Ictalurus punctatus | 60.29 | 3e-76 | 236 |
| LLPS-Tar-0998 | Takifugu rubripes | 60.09 | 4e-82 | 250 |
| LLPS-Orl-4005 | Oryzias latipes | 58.8 | 1e-79 | 244 |
| LLPS-Scm-0655 | Scophthalmus maximus | 58.57 | 1e-76 | 239 |
| LLPS-Ten-2241 | Tetraodon nigroviridis | 55.5 | 4e-74 | 230 |
| LLPS-Gaa-0224 | Gasterosteus aculeatus | 54.59 | 1e-62 | 201 |
| LLPS-Phv-0043 | Phaseolus vulgaris | 49.05 | 1e-57 | 189 |
| LLPS-Glm-1987 | Glycine max | 48.83 | 7e-59 | 191 |
| LLPS-Via-1874 | Vigna angularis | 48.54 | 2e-56 | 185 |
| LLPS-Met-0910 | Medicago truncatula | 47.37 | 8e-60 | 194 |
| LLPS-Sot-2135 | Solanum tuberosum | 45.5 | 1e-52 | 176 |
| LLPS-Orb-2016 | Oryza barthii | 45.31 | 4e-31 | 119 |
| LLPS-Hea-2706 | Helianthus annuus | 45.28 | 4e-55 | 182 |
| LLPS-Dac-0817 | Daucus carota | 44.81 | 3e-47 | 170 |
| LLPS-Cus-1892 | Cucumis sativus | 44.76 | 2e-52 | 175 |
| LLPS-Thc-2505 | Theobroma cacao | 44.55 | 4e-52 | 174 |
| LLPS-Prp-0474 | Prunus persica | 44.44 | 2e-51 | 173 |
| LLPS-Viv-1152 | Vitis vinifera | 44.29 | 1e-54 | 181 |
| LLPS-Nia-0763 | Nicotiana attenuata | 43.95 | 1e-50 | 171 |
| LLPS-Mua-2282 | Musa acuminata | 43.81 | 4e-47 | 162 |
| LLPS-Coc-0087 | Corchorus capsularis | 43.75 | 2e-54 | 181 |
| LLPS-Arl-0036 | Arabidopsis lyrata | 43.64 | 2e-51 | 173 |
| LLPS-Art-2362 | Arabidopsis thaliana | 43.44 | 2e-50 | 171 |
| LLPS-Brn-0895 | Brassica napus | 43.38 | 9e-49 | 166 |
| LLPS-Brr-1999 | Brassica rapa | 43.38 | 1e-48 | 166 |
| LLPS-Bro-2014 | Brassica oleracea | 42.92 | 2e-45 | 164 |
| LLPS-Cae-1700 | Caenorhabditis elegans | 42.47 | 1e-48 | 164 |
| LLPS-Pot-1645 | Populus trichocarpa | 42.38 | 1e-46 | 161 |
| LLPS-Sem-2110 | Selaginella moellendorffii | 42.33 | 5e-46 | 158 |
| LLPS-Amt-0685 | Amborella trichopoda | 41.83 | 3e-42 | 155 |
| LLPS-Orm-1949 | Oryza meridionalis | 41.21 | 2e-34 | 129 |
| LLPS-Sol-2356 | Solanum lycopersicum | 41.03 | 2e-45 | 164 |
| LLPS-Mae-0882 | Manihot esculenta | 40.74 | 4e-50 | 169 |
| LLPS-Tra-0899 | Triticum aestivum | 40.72 | 4e-40 | 143 |
| LLPS-Php-0967 | Physcomitrella patens | 40.71 | 2e-48 | 165 |
| LLPS-Orni-1247 | Oryza nivara | 40.64 | 7e-40 | 142 |
| LLPS-Ori-1241 | Oryza indica | 40.64 | 7e-40 | 142 |
| LLPS-Ors-1492 | Oryza sativa | 40.64 | 7e-40 | 142 |
| LLPS-Org-2064 | Oryza glaberrima | 40.64 | 7e-40 | 142 |
| LLPS-Orr-1262 | Oryza rufipogon | 40.64 | 7e-40 | 142 |
| LLPS-Brd-1988 | Brachypodium distachyon | 40.58 | 4e-39 | 141 |
| LLPS-Orbr-1099 | Oryza brachyantha | 40.47 | 8e-46 | 158 |
| LLPS-Lep-0438 | Leersia perrieri | 40.28 | 3e-44 | 154 |
| LLPS-Dos-0784 | Dothistroma septosporum | 40.0 | 1e-43 | 152 |
| LLPS-Trv-1030 | Trichoderma virens | 40.0 | 8e-40 | 142 |
| LLPS-Hov-0739 | Hordeum vulgare | 39.73 | 3e-41 | 147 |
| LLPS-Sei-0317 | Setaria italica | 39.17 | 5e-47 | 161 |
| LLPS-Sob-1059 | Sorghum bicolor | 39.17 | 2e-45 | 157 |
| LLPS-Drm-2198 | Drosophila melanogaster | 39.11 | 3e-38 | 137 |
| LLPS-Zem-2414 | Zea mays | 38.71 | 3e-46 | 159 |
| LLPS-Orp-1657 | Oryza punctata | 38.6 | 2e-38 | 139 |
| LLPS-Coo-0937 | Colletotrichum orbiculare | 38.3 | 5e-37 | 135 |
| LLPS-Nec-1275 | Neurospora crassa | 38.03 | 2e-38 | 140 |
| LLPS-Yal-1075 | Yarrowia lipolytica | 37.93 | 2e-35 | 131 |
| LLPS-Ved-0996 | Verticillium dahliae | 37.13 | 2e-37 | 136 |
| LLPS-Mao-1225 | Magnaporthe oryzae | 37.12 | 2e-32 | 123 |
| LLPS-Lem-0143 | Leptosphaeria maculans | 36.84 | 3e-36 | 133 |
| LLPS-Cog-0691 | Colletotrichum gloeosporioides | 36.64 | 2e-35 | 136 |
| LLPS-Cogr-1168 | Colletotrichum graminicola | 36.44 | 3e-34 | 128 |
| LLPS-Zyt-1300 | Zymoseptoria tritici | 36.28 | 8e-36 | 132 |
| LLPS-Gor-0387 | Gossypium raimondii | 35.89 | 2e-40 | 144 |
| LLPS-Pytr-0945 | Pyrenophora triticirepentis | 35.87 | 6e-32 | 122 |
| LLPS-Phn-0574 | Phaeosphaeria nodorum | 35.22 | 1e-37 | 137 |
| LLPS-Blg-0816 | Blumeria graminis | 35.15 | 1e-35 | 132 |
| LLPS-Asg-1172 | Ashbya gossypii | 34.68 | 4e-31 | 120 |
| LLPS-Sac-0387 | Saccharomyces cerevisiae | 34.65 | 4e-33 | 125 |
| LLPS-Fus-1126 | Fusarium solani | 34.65 | 7e-27 | 108 |
| LLPS-Fuv-1182 | Fusarium verticillioides | 33.88 | 1e-28 | 114 |
| LLPS-Gag-0833 | Gaeumannomyces graminis | 33.88 | 6e-33 | 125 |
| LLPS-Miv-0261 | Microbotryum violaceum | 33.58 | 2e-13 | 71.2 |
| LLPS-Tum-1431 | Tuber melanosporum | 33.46 | 2e-28 | 113 |
| LLPS-Pyt-1294 | Pyrenophora teres | 33.04 | 1e-24 | 102 |
| LLPS-Fuo-0275 | Fusarium oxysporum | 32.92 | 6e-24 | 100 |
| LLPS-Scs-0591 | Sclerotinia sclerotiorum | 32.52 | 9e-11 | 61.2 |
| LLPS-Map-1330 | Magnaporthe poae | 32.37 | 9e-31 | 119 |
| LLPS-Kop-0703 | Komagataella pastoris | 32.2 | 3e-25 | 104 |
| LLPS-Usm-0112 | Ustilago maydis | 31.06 | 6e-15 | 75.9 |
| LLPS-Chr-1725 | Chlamydomonas reinhardtii | 30.08 | 1e-07 | 53.9 |
| LLPS-Spr-1302 | Sporisorium reilianum | 27.81 | 1e-12 | 69.3 |