LLPS-Fec-4656
RBFOX3
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | RNA binding protein fox-1 homolog |
| Gene Name: | RBFOX3 |
| Ensembl Gene: | ENSFCAG00000002555.5 |
| Ensembl Protein: | ENSFCAP00000045398.1 |
| Organism: | Felis catus |
| Taxa ID: | 9685 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule | Predicted from orthologs | (View) |
▼ FUNCTION
| RNA-binding protein that regulates alternative splicing events. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSFCAT00000065033.1 | ENSFCAP00000045398.1 |
| Ensembl | ENSFCAT00000065518.1 | ENSFCAP00000047377.1 |
| Ensembl | ENSFCAT00000059700.1 | ENSFCAP00000040779.1 |
| Ensembl | ENSFCAT00000002555.5 | ENSFCAP00000002353.5 |
| UniProt | A0A337S2A1, A0A337S2A1_FELCA | |
| GeneBank | AANG04004184 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MLCSMANSGC LLLSNSGSML PHSVPCPPAF LYLQQGNQDA TAPPEAMAQP YPPAQYPPPP 60 61 QNGIPAEYAP PPPHPTQEYS GQTPVPPEHG MTLYTPAQTH PEQPGPEAST QPIAGAQTVP 120 121 QTDEAAQTDS QPLHSSDHTE KQQPKRLHVS NIPFRFRDPD LRQMFGQFGK ILDVEIIFNE 180 181 RGSKGFGFVT FETSSDADRA REKLNGTIVE GRKIEVNNAT ARVMTNKKTA NPYTNGWKLN 240 241 PVVGAVYGPE FYAVTGFPYP TTGTAVAYRG AHLRGRGRAV YNTFRAAPPP PPIPTYGAVV 300 301 YQDGFYGAEI YGGYAAYRYA QPAAAAAAYS DSYGRVYAAT DPYHHTIGPP ATYSIGTM 358 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCCCAGC CCTACCCCCC CGCCCAGTAC CCCCCTCCGC CACAGAACGG CATCCCCGCC 60 61 GAGTACGCGC CACCCCCTCC GCACCCCACG CAGGAGTACT CGGGCCAGAC CCCGGTCCCC 120 121 CCGGAGCACG GCATGACCCT GTACACACCA GCACAGACCC ACCCCGAGCA GCCGGGCCCC 180 181 GAGGCCAGCA CGCAGCCCAT CGCTGGGGCC CAGACTGTGC CGCAGACAGA CGAGGCGGCA 240 241 CAGACGGACA GCCAGCCGCT CCACTCCTCC GACCACACAG AGAAGCAGCA GCCCAAGCGG 300 301 CTACACGTCT CCAACATCCC CTTCCGGTTC AGGGACCCCG ACCTGCGGCA AATGTTCGGG 360 361 CAATTCGGAA AAATTTTAGA CGTGGAGATC ATTTTTAACG AGCGGGGCTC CAAGGTCAAT 420 421 AACGCCACAG CCCGCGTCAT GACCAACAAG AAGACTGCGA ACCCCTACAC TAACGGCTGG 480 481 AAGCTAAACC CCGTGGTGGG CGCAGTCTAT GGGCCTGAAT TCTATGCAGT GACGGGGTTC 540 541 CCCTACCCCA CCACGGGCAC GGCCGTAGCC TACAGGGGCG CGCACCTACG GGGTCGGGGC 600 601 CGGGCCGTGT ATAATACGTT TCGGGCTGCG CCGCCCCCGC CCCCCATCCC AACTTATGGA 660 661 GCGGCACTGG AGCAAACGCT TGTTAAAATG CCAGTCCCAT GGGCAGGGCT GGCACCCTGC 720 721 CCCCTCCCTC CTCAGCAGAC GCCGGAGCCG GCCTGCCCAC CACTCTCTTG TCCGTTTGCT 780 781 TCCAGGGTCG TGTATCAGGA CGGCTTTTAT GGTGCTGAGA TTTATGGGGG CTATGCAGCC 840 841 TACAGATACG CTCAGCCTGC AGCAGCAGCC GCGGCCTATA GCGACAGTTA CGGCAGAGTC 900 901 TATGCGGCCA CCGACCCCTA CCACCACACC ATCGGCCCCC CAGCGACCTA CAGCATCGGA 960 961 ACCATGTGA 969 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Nucleus | |
Molecular Function | RNA binding | |
Biological Process | MRNA processing | |
Biological Process | Regulation of RNA splicing | |
Biological Process | RNA splicing |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Caf-1903 | Canis familiaris | 97.9 | 1e-135 | 396 |
| LLPS-Chs-4406 | Chlorocebus sabaeus | 97.31 | 2e-173 | 492 |
| LLPS-Urm-3899 | Ursus maritimus | 97.1 | 2e-30 | 120 |
| LLPS-Bot-3728 | Bos taurus | 96.28 | 2e-154 | 446 |
| LLPS-Rhb-2450 | Rhinopithecus bieti | 95.85 | 8e-150 | 436 |
| LLPS-Cas-1986 | Carlito syrichta | 95.85 | 6e-150 | 434 |
| LLPS-Man-2921 | Macaca nemestrina | 95.44 | 2e-148 | 432 |
| LLPS-Pap-0649 | Pan paniscus | 95.44 | 1e-148 | 431 |
| LLPS-Mam-0988 | Macaca mulatta | 95.44 | 5e-149 | 432 |
| LLPS-Cap-3988 | Cavia porcellus | 95.44 | 3e-150 | 436 |
| LLPS-Cea-1128 | Cercocebus atys | 95.44 | 1e-148 | 432 |
| LLPS-Maf-4363 | Macaca fascicularis | 95.44 | 2e-148 | 432 |
| LLPS-Paa-0884 | Papio anubis | 95.44 | 8e-149 | 433 |
| LLPS-Mal-3432 | Mandrillus leucophaeus | 95.44 | 7e-149 | 433 |
| LLPS-Otg-3345 | Otolemur garnettii | 95.4 | 4e-172 | 491 |
| LLPS-Sus-2617 | Sus scrofa | 95.28 | 5e-135 | 395 |
| LLPS-Ran-3168 | Rattus norvegicus | 94.19 | 1e-147 | 429 |
| LLPS-Pes-3330 | Pelodiscus sinensis | 94.12 | 5e-12 | 71.2 |
| LLPS-Mod-2844 | Monodelphis domestica | 93.58 | 0.0 | 514 |
| LLPS-Myl-3759 | Myotis lucifugus | 93.5 | 8e-70 | 221 |
| LLPS-Mum-4573 | Mus musculus | 93.36 | 2e-146 | 426 |
| LLPS-Fud-1402 | Fukomys damarensis | 93.1 | 4e-08 | 58.5 |
| LLPS-Dio-3651 | Dipodomys ordii | 93.1 | 4e-08 | 58.5 |
| LLPS-Gaga-1586 | Gallus gallus | 93.02 | 3e-179 | 514 |
| LLPS-Nol-3417 | Nomascus leucogenys | 92.93 | 4e-110 | 329 |
| LLPS-Aim-0253 | Ailuropoda melanoleuca | 92.11 | 1e-168 | 483 |
| LLPS-Meg-0177 | Meleagris gallopavo | 91.32 | 5e-117 | 347 |
| LLPS-Eqc-4591 | Equus caballus | 91.3 | 3e-171 | 488 |
| LLPS-Poa-3408 | Pongo abelii | 89.96 | 2e-136 | 399 |
| LLPS-Anc-3146 | Anolis carolinensis | 88.61 | 2e-170 | 486 |
| LLPS-Mup-1513 | Mustela putorius furo | 87.81 | 5e-168 | 481 |
| LLPS-Orc-3599 | Oryctolagus cuniculus | 86.21 | 1e-07 | 57.0 |
| LLPS-Sah-2677 | Sarcophilus harrisii | 84.27 | 8e-158 | 456 |
| LLPS-Pat-4391 | Pan troglodytes | 83.72 | 2e-162 | 467 |
| LLPS-Gog-1233 | Gorilla gorilla | 83.72 | 2e-162 | 467 |
| LLPS-Hos-2469 | Homo sapiens | 83.43 | 4e-160 | 460 |
| LLPS-Caj-4032 | Callithrix jacchus | 82.56 | 3e-158 | 456 |
| LLPS-Loa-4183 | Loxodonta africana | 82.44 | 2e-161 | 465 |
| LLPS-Anp-2346 | Anas platyrhynchos | 81.03 | 3e-56 | 192 |
| LLPS-Dar-0980 | Danio rerio | 77.74 | 6e-118 | 353 |
| LLPS-Asm-3896 | Astyanax mexicanus | 77.23 | 2e-140 | 411 |
| LLPS-Scm-0870 | Scophthalmus maximus | 77.13 | 3e-143 | 418 |
| LLPS-Fia-1260 | Ficedula albicollis | 75.91 | 1e-130 | 387 |
| LLPS-Scf-1703 | Scleropages formosus | 75.34 | 2e-94 | 292 |
| LLPS-Aon-2977 | Aotus nancymaae | 73.84 | 3e-130 | 384 |
| LLPS-Ict-3593 | Ictidomys tridecemlineatus | 72.43 | 2e-122 | 362 |
| LLPS-Tag-3364 | Taeniopygia guttata | 70.34 | 2e-116 | 350 |
| LLPS-Leo-2342 | Lepisosteus oculatus | 70.25 | 5e-120 | 360 |
| LLPS-Ora-1277 | Ornithorhynchus anatinus | 70.0 | 2e-110 | 334 |
| LLPS-Orn-2894 | Oreochromis niloticus | 69.11 | 1e-127 | 378 |
| LLPS-Ten-0840 | Tetraodon nigroviridis | 68.87 | 1e-126 | 376 |
| LLPS-Ova-0869 | Ovis aries | 68.75 | 6e-98 | 303 |
| LLPS-Tar-1018 | Takifugu rubripes | 65.08 | 2e-112 | 340 |
| LLPS-Icp-1020 | Ictalurus punctatus | 64.94 | 4e-76 | 248 |
| LLPS-Tut-0015 | Tursiops truncatus | 64.5 | 2e-116 | 351 |
| LLPS-Xet-2681 | Xenopus tropicalis | 63.61 | 2e-113 | 342 |
| LLPS-Xim-0110 | Xiphophorus maculatus | 63.2 | 2e-79 | 257 |
| LLPS-Orl-2845 | Oryzias latipes | 62.4 | 1e-78 | 255 |
| LLPS-Cae-2013 | Caenorhabditis elegans | 61.96 | 9e-31 | 125 |
| LLPS-Lac-0757 | Latimeria chalumnae | 56.25 | 3e-82 | 262 |
| LLPS-Gaa-1024 | Gasterosteus aculeatus | 55.97 | 1e-67 | 224 |
| LLPS-Pof-1427 | Poecilia formosa | 55.38 | 6e-77 | 251 |
| LLPS-Mea-0106 | Mesocricetus auratus | 54.59 | 7e-89 | 279 |
| LLPS-Ere-0206 | Erinaceus europaeus | 45.0 | 2e-09 | 61.6 |
| LLPS-Dac-1385 | Daucus carota | 44.0 | 2e-10 | 64.7 |
| LLPS-Tra-1142 | Triticum aestivum | 42.5 | 1e-09 | 60.8 |
| LLPS-Pot-2655 | Populus trichocarpa | 41.98 | 1e-09 | 62.8 |
| LLPS-Drm-0962 | Drosophila melanogaster | 41.18 | 9e-10 | 64.3 |
| LLPS-Sot-0829 | Solanum tuberosum | 40.74 | 2e-09 | 62.0 |
| LLPS-Sob-1001 | Sorghum bicolor | 40.51 | 2e-10 | 65.1 |
| LLPS-Mae-2025 | Manihot esculenta | 39.76 | 7e-10 | 63.9 |
| LLPS-Prp-2015 | Prunus persica | 39.24 | 3e-10 | 64.7 |
| LLPS-Brd-0209 | Brachypodium distachyon | 39.24 | 2e-09 | 62.4 |
| LLPS-Hov-1352 | Hordeum vulgare | 37.18 | 9e-10 | 63.5 |
| LLPS-Coc-2363 | Corchorus capsularis | 31.72 | 1e-09 | 62.8 |