LLPS-Ere-0204
LATS1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | serine/threonine-protein kinase LATS1 isoform X2 |
| Gene Name: | LATS1 |
| Ensembl Gene: | ENSEEUG00000007451.1 |
| Ensembl Protein: | ENSEEUP00000006784.1 |
| Organism: | Erinaceus europaeus |
| Taxa ID: | 9365 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Centrosome/Spindle pole body | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSEEUT00000007438.1 | ENSEEUP00000006784.1 |
| UniProt | A0A1S2Z9H8, A0A1S2Z9H8_ERIEU | |
| RefSeq | , XM_007515882.1 | , XP_007515944.1, XP_007515944.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MKRSEKPEGY RQMRPKTFPA SNYTGSSRQM LQEIRESLRN LSKPSDAAKA EYNMSKMSTE 60 61 DPRQVRNPHK FGTHHKALLE IRNSLLPFAN ETSSSSRSSS EVNPQMLQDL QAAGFDEDMV 120 121 IQALQKTNNR SIEAAIEFIS KMSYQDLRRE QMAAAAARPV NASLKPGSVN RKQSWKGSKE 180 181 SLAPQRHGGP LGESVAYHPD SPNSQTDVGR PLSGSGLTAF AQGHPSNGQR VNPPPPPQVR 240 241 SVTPPPPPRG QTPPPRGTTP PPPSWEPTSQ TKRYSGNMDY AIPRISPVPP GAWQEGYPPP 300 301 PLNTSPAGQG QRGISSVPVG RQPIIMQSSN KYNFPSGRPG IQNGSGQTDF LIHQNVPSGT 360 361 VSRQPPPPYP LSTTNGQSAS ALQTGGSAAP SSYTNGNIPQ SLMAPNRNSH NLELYNITVP 420 421 GLQTAWPQSS SAPAQSSPSS GHDMPTWQPN IPVRSNSFNN PLGSRTSHSA NSQSSATTVT 480 481 AITPAPIQQP VKSIRVLKPE LQTALAPTHP SWLPQPIQTV QPSPFSEGPP ANMTVMPPVA 540 541 EAPNYQGPPP PYPKHLLHQN PPFPPYESVP KPGKEDQPSL PKEDEGDKSY ENADAGDKEK 600 601 KQITTSPITV RKNKKDEERR ESRIQSYSPQ AFKFFMEQHV ENVLKSHQQR LHRKKQLENE 660 661 MMRVGLSQDA QDQMRKMLCQ KESNYIRLKR AKMDKSMFVK IKTLGIGAFG EVCLARKVDT 720 721 KALYATKTLR KKDVLLRNQV AHVKAERDIL AEADNEWVVR LYYSFQDKDN LYFVMDYIPG 780 781 GDMMSLLIRM GIFSEKLARF YIAELTCAVE SVHKMGFIHR DIKPDNILID RDGHIKLTDF 840 841 GLCTGFRWTH DSKYYQSGDH PRQDSMDFSI EWGDPSNCRC GDRLKPLERR AARQHQRCLA 900 901 HSLVGTPNYI APEVLLRTGY TQLCDWWSVG VILFEMLVGQ PPFLAQTPLE TQLKVINWQT 960 961 SLHIPPQAKL SPEASDLIIK LCRGPEDRLG KNGADEIKAH PFFKTIDFSS DLRQQSASYI 1020 1021 PKITHPTDTS NFDPVDPDKL WSDDNEEENV SDTLNGWYKN GKHPEHAFYE FTFRRFFDDN 1080 1081 GYPYNYPKPI EFEYIKSQGL EQQSDEDDQH TGSEIKNRDL VYV 1123 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGAAGAGGA GTGAAAAGCC AGAGGGATAT AGACAGATGA GGCCTAAGAC CTTTCCTGCC 60 61 AGTAATTACA CTGGCAGCAG CAGGCAGATG TTGCAAGAAA TTCGGGAATC CCTGCGGAAT 120 121 TTATCCAAGC CGTCAGATGC AGCCAAGGCC GAGTACAACA TGAGTAAAAT GTCAACTGAA 180 181 GATCCTCGAC AAGTCAGAAA CCCACATAAA TTTGGGACGC ATCATAAAGC CTTGCTAGAA 240 241 ATCCGCAACT CTCTGCTACC GTTTGCAAAC GAGACAAGTT CTTCCTCCCG GAGTTCTTCC 300 301 GAAGTTAATC CACAAATGCT CCAAGACTTG CAAGCTGCTG GGTTTGATGA GGATATGGTT 360 361 ATACAAGCCC TTCAGAAAAC TAATAACAGA AGTATAGAAG CTGCCATTGA ATTCATTAGT 420 421 AAAATGAGTT ACCAAGATTT GCGACGGGAA CAGATGGCTG CAGCAGCTGC CAGGCCTGTT 480 481 AATGCCAGCC TGAAGCCAGG GAGTGTGAAC CGCAAACAAA GCTGGAAAGG TTCTAAGGAA 540 541 TCCTTAGCTC CTCAGAGGCA CGGAGGGCCC CTAGGAGAAA GTGTGGCCTA CCATCCGGAT 600 601 AGCCCCAACT CGCAGACAGA CGTAGGAAGG CCTTTGTCAG GATCTGGTCT GACAGCGTTT 660 661 GCTCAAGGCC ACCCTAGCAA TGGGCAGAGA GTGAACCCCC CACCGCCTCC CCAAGTCAGG 720 721 AGTGTCACTC CCCCGCCACC GCCAAGGGGC CAGACTCCTC CCCCAAGAGG AACCACGCCA 780 781 CCTCCTCCCT CCTGGGAACC GACTTCGCAA ACAAAGCGCT ATTCTGGGAA CATGGACTAT 840 841 GCAATCCCTC GGATCTCTCC TGTTCCACCT GGAGCCTGGC AGGAGGGCTA TCCGCCACCC 900 901 CCTCTTAACA CATCCCCTGC TGGCCAAGGA CAAAGAGGCA TTAGTTCTGT TCCTGTTGGC 960 961 AGACAGCCAA TCATCATGCA GAGTTCTAAC AAATACAACT TTCCTTCAGG GAGACCTGGA 1020 1021 ATTCAGAACG GTAGTGGGCA GACTGACTTT CTGATACACC AGAATGTTCC TTCTGGCACC 1080 1081 GTGAGTCGGC AGCCACCCCC TCCGTACCCT CTGTCCACAA CTAACGGGCA AAGTGCTTCT 1140 1141 GCTTTACAGA CGGGTGGATC TGCTGCCCCT TCGTCATACA CCAACGGAAA CATTCCTCAG 1200 1201 TCTCTGATGG CGCCAAACAG GAACAGTCAC AACTTGGAGC TGTATAACAT CACTGTACCC 1260 1261 GGACTGCAGA CAGCCTGGCC TCAGTCGTCT TCTGCGCCAG CCCAGTCGTC CCCAAGCAGT 1320 1321 GGGCACGATA TGCCTACCTG GCAGCCCAAC ATACCAGTCA GGTCAAATTC TTTTAATAAC 1380 1381 CCACTGGGGA GCAGAACAAG TCACTCTGCT AATTCTCAGT CTTCAGCTAC CACAGTCACT 1440 1441 GCTATTACGC CGGCTCCTAT CCAGCAGCCG GTGAAAAGTA TACGTGTATT AAAGCCAGAG 1500 1501 CTACAGACTG CTTTAGCCCC TACGCACCCT TCTTGGTTAC CGCAGCCAAT TCAAACTGTT 1560 1561 CAACCTAGTC CTTTTTCTGA GGGCCCCCCT GCAAATATGA CCGTTATGCC ACCCGTGGCT 1620 1621 GAAGCGCCCA ACTACCAAGG TCCGCCTCCG CCCTACCCAA AACACCTGCT ACATCAAAAC 1680 1681 CCCCCTTTCC CTCCGTATGA GTCAGTCCCT AAACCAGGCA AAGAGGATCA GCCAAGCTTG 1740 1741 CCCAAGGAAG ATGAGGGGGA CAAAAGTTAT GAAAATGCTG ATGCTGGGGA TAAAGAAAAG 1800 1801 AAACAGATCA CAACTTCACC CATCACCGTC CGGAAAAACA AGAAAGATGA AGAGCGAAGA 1860 1861 GAGTCTAGAA TTCAGAGTTA TTCTCCTCAG GCATTTAAAT TCTTTATGGA GCAGCATGTA 1920 1921 GAAAACGTCC TGAAGTCTCA TCAGCAGCGT CTACATCGAA AAAAACAATT AGAGAATGAA 1980 1981 ATGATGCGGG TTGGATTATC TCAGGACGCC CAGGATCAAA TGAGAAAGAT GCTTTGCCAA 2040 2041 AAAGAGTCTA ATTACATCCG CCTTAAGAGG GCTAAAATGG ACAAGTCTAT GTTTGTGAAG 2100 2101 ATAAAGACAC TAGGAATAGG AGCTTTTGGT GAAGTTTGTC TAGCAAGAAA AGTAGATACT 2160 2161 AAAGCTTTGT ATGCAACAAA AACTCTTCGA AAGAAAGATG TTTTGCTTCG AAACCAAGTT 2220 2221 GCTCATGTGA AAGCTGAGAG AGATATCCTG GCAGAAGCTG ATAACGAATG GGTAGTCCGT 2280 2281 CTCTATTATT CATTCCAAGA TAAGGACAAC TTATACTTTG TCATGGACTA TATTCCGGGG 2340 2341 GGTGATATGA TGAGCCTGTT AATTAGAATG GGGATCTTTT CGGAAAAGCT AGCACGGTTC 2400 2401 TACATAGCAG AACTTACTTG TGCAGTGGAA AGTGTCCATA AAATGGGTTT TATTCATAGA 2460 2461 GATATTAAGC CTGATAACAT TTTGATTGAT CGTGATGGTC ACATTAAATT GACTGACTTT 2520 2521 GGCCTCTGCA CTGGCTTCAG ATGGACACAT GACTCTAAAT ACTATCAGAG TGGGGACCAT 2580 2581 CCACGACAAG ACAGCATGGA TTTCAGTATT GAATGGGGTG ACCCCTCTAA CTGTCGATGC 2640 2641 GGAGACAGAC TGAAGCCACT GGAGCGGAGA GCTGCACGCC AGCACCAGCG ATGTCTAGCA 2700 2701 CACTCCTTGG TTGGGACTCC TAATTACATT GCACCAGAAG TCTTGTTACG GACAGGCTAT 2760 2761 ACACAGTTAT GTGACTGGTG GAGTGTTGGT GTAATTCTTT TTGAAATGCT GGTGGGACAA 2820 2821 CCCCCTTTCT TGGCACAAAC TCCACTAGAA ACACAACTGA AGGTTATCAA CTGGCAAACA 2880 2881 TCTCTTCACA TTCCGCCACA AGCGAAGCTG AGTCCTGAAG CATCTGATCT TATTATTAAA 2940 2941 CTTTGCCGAG GACCAGAAGA TCGCTTGGGC AAGAATGGTG CTGATGAAAT AAAAGCTCAT 3000 3001 CCATTTTTTA AAACAATTGA TTTCTCCAGT GACCTGAGAC AGCAGTCTGC TTCATACATT 3060 3061 CCTAAAATCA CACATCCAAC AGATACATCG AATTTTGATC CTGTGGATCC CGATAAGTTA 3120 3121 TGGAGTGATG ATAATGAAGA AGAAAATGTC AGTGACACTC TCAACGGATG GTATAAAAAT 3180 3181 GGGAAGCACC CTGAACATGC TTTCTATGAA TTTACCTTTC GGAGATTTTT TGATGACAAT 3240 3241 GGTTATCCAT ATAATTATCC AAAGCCCATT GAATTTGAAT ATATTAAATC ACAAGGCTTA 3300 3301 GAGCAACAGT CAGATGAAGA TGATCAGCAC ACAGGCTCAG AGATAAAAAA TCGTGATCTA 3360 3361 GTTTATGTTT AG 3372 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Mal-2628 | Mandrillus leucophaeus | 96.98 | 0.0 | 566 |
| LLPS-Orc-4328 | Oryctolagus cuniculus | 93.88 | 0.0 | 1464 |
| LLPS-Urm-2805 | Ursus maritimus | 93.74 | 0.0 | 1691 |
| LLPS-Fec-0195 | Felis catus | 93.54 | 0.0 | 1982 |
| LLPS-Man-2144 | Macaca nemestrina | 93.1 | 0.0 | 1996 |
| LLPS-Paa-2765 | Papio anubis | 93.1 | 0.0 | 1999 |
| LLPS-Maf-4833 | Macaca fascicularis | 93.02 | 0.0 | 1996 |
| LLPS-Caf-4008 | Canis familiaris | 93.01 | 0.0 | 1975 |
| LLPS-Cea-4194 | Cercocebus atys | 93.0 | 0.0 | 1792 |
| LLPS-Aon-4063 | Aotus nancymaae | 92.93 | 0.0 | 1993 |
| LLPS-Gog-2075 | Gorilla gorilla | 92.93 | 0.0 | 1994 |
| LLPS-Rhb-3719 | Rhinopithecus bieti | 92.91 | 0.0 | 1793 |
| LLPS-Mam-2541 | Macaca mulatta | 92.84 | 0.0 | 1992 |
| LLPS-Pat-2525 | Pan troglodytes | 92.84 | 0.0 | 1992 |
| LLPS-Pap-4303 | Pan paniscus | 92.84 | 0.0 | 1992 |
| LLPS-Chs-4574 | Chlorocebus sabaeus | 92.84 | 0.0 | 1995 |
| LLPS-Poa-1002 | Pongo abelii | 92.75 | 0.0 | 1992 |
| LLPS-Eqc-0360 | Equus caballus | 92.75 | 0.0 | 1954 |
| LLPS-Cas-3613 | Carlito syrichta | 92.75 | 0.0 | 1958 |
| LLPS-Hos-1421 | Homo sapiens | 92.75 | 0.0 | 1989 |
| LLPS-Aim-2285 | Ailuropoda melanoleuca | 92.75 | 0.0 | 1981 |
| LLPS-Nol-3095 | Nomascus leucogenys | 92.57 | 0.0 | 1999 |
| LLPS-Mup-2698 | Mustela putorius furo | 92.57 | 0.0 | 1964 |
| LLPS-Caj-4791 | Callithrix jacchus | 92.57 | 0.0 | 1992 |
| LLPS-Ova-1763 | Ovis aries | 92.14 | 0.0 | 1947 |
| LLPS-Ict-0070 | Ictidomys tridecemlineatus | 92.04 | 0.0 | 1943 |
| LLPS-Sus-2974 | Sus scrofa | 92.04 | 0.0 | 1964 |
| LLPS-Bot-3127 | Bos taurus | 91.95 | 0.0 | 1939 |
| LLPS-Myl-3215 | Myotis lucifugus | 91.86 | 0.0 | 1951 |
| LLPS-Fud-4074 | Fukomys damarensis | 91.69 | 0.0 | 1945 |
| LLPS-Tut-2112 | Tursiops truncatus | 91.58 | 0.0 | 1605 |
| LLPS-Dio-4184 | Dipodomys ordii | 91.51 | 0.0 | 1925 |
| LLPS-Loa-4115 | Loxodonta africana | 91.08 | 0.0 | 1914 |
| LLPS-Otg-4295 | Otolemur garnettii | 90.91 | 0.0 | 1915 |
| LLPS-Cap-1113 | Cavia porcellus | 90.65 | 0.0 | 1598 |
| LLPS-Mum-4184 | Mus musculus | 89.47 | 0.0 | 1906 |
| LLPS-Ran-0920 | Rattus norvegicus | 89.39 | 0.0 | 1905 |
| LLPS-Sah-1623 | Sarcophilus harrisii | 87.22 | 0.0 | 1856 |
| LLPS-Mea-4017 | Mesocricetus auratus | 86.42 | 0.0 | 1812 |
| LLPS-Mod-4359 | Monodelphis domestica | 85.76 | 0.0 | 1821 |
| LLPS-Ora-3225 | Ornithorhynchus anatinus | 83.91 | 0.0 | 1569 |
| LLPS-Pes-0410 | Pelodiscus sinensis | 82.8 | 0.0 | 1429 |
| LLPS-Anp-2276 | Anas platyrhynchos | 82.21 | 0.0 | 1731 |
| LLPS-Tag-0627 | Taeniopygia guttata | 81.56 | 0.0 | 1728 |
| LLPS-Gaga-3981 | Gallus gallus | 81.55 | 0.0 | 1737 |
| LLPS-Fia-2623 | Ficedula albicollis | 81.47 | 0.0 | 1741 |
| LLPS-Meg-0797 | Meleagris gallopavo | 81.4 | 0.0 | 1736 |
| LLPS-Anc-1601 | Anolis carolinensis | 80.28 | 0.0 | 1724 |
| LLPS-Lac-1182 | Latimeria chalumnae | 77.09 | 0.0 | 1651 |
| LLPS-Drm-1241 | Drosophila melanogaster | 74.59 | 0.0 | 662 |
| LLPS-Gaa-3515 | Gasterosteus aculeatus | 74.22 | 0.0 | 796 |
| LLPS-Scf-2945 | Scleropages formosus | 73.04 | 0.0 | 642 |
| LLPS-Xet-3885 | Xenopus tropicalis | 71.8 | 0.0 | 1227 |
| LLPS-Leo-1076 | Lepisosteus oculatus | 67.32 | 0.0 | 1335 |
| LLPS-Cii-2222 | Ciona intestinalis | 66.12 | 9e-161 | 490 |
| LLPS-Asm-2514 | Astyanax mexicanus | 65.95 | 0.0 | 1320 |
| LLPS-Tar-0094 | Takifugu rubripes | 64.66 | 0.0 | 1270 |
| LLPS-Icp-3189 | Ictalurus punctatus | 63.65 | 0.0 | 1251 |
| LLPS-Ten-1424 | Tetraodon nigroviridis | 62.62 | 0.0 | 1190 |
| LLPS-Orl-0452 | Oryzias latipes | 62.13 | 0.0 | 852 |
| LLPS-Scm-0065 | Scophthalmus maximus | 61.58 | 0.0 | 845 |
| LLPS-Dar-3697 | Danio rerio | 61.39 | 0.0 | 855 |
| LLPS-Xim-0113 | Xiphophorus maculatus | 61.34 | 0.0 | 1160 |
| LLPS-Orn-1174 | Oreochromis niloticus | 61.12 | 0.0 | 838 |
| LLPS-Pof-1925 | Poecilia formosa | 60.45 | 0.0 | 1142 |
| LLPS-Cae-1695 | Caenorhabditis elegans | 50.75 | 7e-140 | 452 |
| LLPS-Tum-0580 | Tuber melanosporum | 48.02 | 3e-121 | 392 |
| LLPS-Sei-0767 | Setaria italica | 46.6 | 2e-114 | 373 |
| LLPS-Sob-1641 | Sorghum bicolor | 46.21 | 1e-113 | 371 |
| LLPS-Glm-2155 | Glycine max | 45.85 | 8e-115 | 374 |
| LLPS-Yal-0600 | Yarrowia lipolytica | 44.95 | 6e-115 | 375 |
| LLPS-Gor-1985 | Gossypium raimondii | 44.55 | 1e-113 | 370 |
| LLPS-Cus-0345 | Cucumis sativus | 43.79 | 2e-117 | 381 |
| LLPS-Prp-0533 | Prunus persica | 43.76 | 1e-115 | 376 |
| LLPS-Coc-0256 | Corchorus capsularis | 43.42 | 3e-115 | 375 |
| LLPS-Hea-1055 | Helianthus annuus | 43.21 | 2e-113 | 370 |
| LLPS-Nia-2390 | Nicotiana attenuata | 43.07 | 1e-118 | 382 |
| LLPS-Mae-1038 | Manihot esculenta | 42.92 | 8e-115 | 374 |
| LLPS-Phv-1020 | Phaseolus vulgaris | 42.76 | 3e-113 | 370 |
| LLPS-Sot-0511 | Solanum tuberosum | 42.33 | 3e-115 | 374 |
| LLPS-Viv-0664 | Vitis vinifera | 42.32 | 8e-114 | 371 |
| LLPS-Sol-2048 | Solanum lycopersicum | 41.9 | 2e-114 | 371 |
| LLPS-Dac-0125 | Daucus carota | 39.66 | 4e-115 | 375 |