LLPS-Dar-4175
ppp2r5a

▼ OVERVIEW

Status: Unreviewed
Protein Name: Serine/threonine protein phosphatase 2A regulatory subunit
Gene Name: ppp2r5a
Ensembl Gene: ENSDARG00000027017.10
Ensembl Protein: ENSDARP00000019419.7
Organism: Danio rerio
Taxa ID: 7955
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSDART00000025644.9ENSDARP00000019419.7
UniProtQ5RHP3, Q5RHP3_DANRE
GeneBankBX510324
Entrez562460

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSAISASEKV  DGFTRKSVRK  AQRQRVCQGS  SQFAVNSSRP  AAPEISALPQ  LKDASSTEQH  60
61    ELFMQKLQQC  CKLFDFYDTV  TDLKSKETKR  ATLSELVDYV  STNRGVLVEP  VYPEITTMVS  120
121   TNIFRTLPPS  ENPDFDPEED  EPTLEASWPH  MQLVYEFFLR  FLENPDFQPS  TAKRYIDQKF  180
181   VLQLLELFDS  EDPREREFLK  TILHRIYGKF  LGLRAFIRKQ  INNIFLRFIY  ETEHFNGVAE  240
241   LLEILGSIIN  GFALPLKAEH  KQFLMKILIP  LHTAKPLALF  HAQLAYCVVQ  FLEKDPTLTE  300
301   VVRGLLKFWP  KTCSQKEVMF  LGEIEEILDV  IEPTQFKKIQ  EPLFKQIAKC  VASPHFQVAE  360
361   RALYYWNNEY  ILSLIEENNA  KIFPIMFGNL  YRISKEHWNP  TIVALVYNVL  KTMMEMNSKL  420
421   FDELTTSYKS  DRQREKKKEQ  EREELWRRLD  ELRMKEVLMI  QNNRHDIQFT  YNNNNHH  477
Nucleotide CDS Sequence (FASTA)
1     ATGTCGGCGA  TTTCTGCGTC  GGAGAAAGTG  GACGGGTTCA  CGCGGAAGTC  TGTGAGGAAG  60
61    GCGCAAAGGC  AGAGGGTATG  CCAGGGCTCG  TCTCAATTTG  CGGTCAACAG  CAGCAGGCCT  120
121   GCGGCTCCAG  AGATCTCGGC  GCTCCCGCAG  CTCAAAGATG  CATCTTCTAC  AGAGCAGCAT  180
181   GAGCTGTTCA  TGCAGAAGCT  ACAGCAGTGC  TGCAAATTGT  TCGACTTCTA  CGACACAGTG  240
241   ACTGACCTAA  AGAGCAAAGA  GACCAAACGG  GCCACTCTCA  GCGAACTCGT  GGATTATGTG  300
301   TCCACTAACA  GAGGCGTTCT  GGTGGAGCCC  GTCTATCCCG  AAATCACCAC  AATGGTCAGC  360
361   ACAAACATTT  TCAGAACACT  TCCACCCAGT  GAAAACCCAG  ACTTTGATCC  AGAAGAAGAT  420
421   GAACCCACGC  TTGAAGCCTC  CTGGCCACAC  ATGCAGTTGG  TGTATGAGTT  TTTCCTTCGA  480
481   TTCCTTGAAA  ATCCAGACTT  CCAGCCAAGC  ACTGCCAAAC  GTTATATTGA  CCAGAAGTTT  540
541   GTGCTACAGC  TTTTAGAGCT  CTTTGACAGT  GAAGATCCTC  GTGAGAGAGA  GTTTTTAAAA  600
601   ACAATTCTGC  ATCGCATCTA  TGGGAAGTTT  CTGGGTTTGC  GTGCCTTTAT  TCGGAAACAG  660
661   ATCAACAACA  TTTTTCTAAG  ATTCATCTAT  GAAACTGAGC  ACTTTAATGG  AGTTGCTGAA  720
721   CTCCTCGAGA  TTCTGGGCAG  TATCATCAAT  GGCTTCGCTC  TGCCGCTGAA  GGCCGAACAC  780
781   AAGCAGTTCC  TCATGAAAAT  CCTCATTCCT  CTGCACACTG  CCAAACCACT  AGCACTGTTC  840
841   CATGCACAGC  TGGCCTACTG  TGTGGTTCAG  TTCTTAGAAA  AGGACCCGAC  ACTTACTGAA  900
901   GTGGTTCGTG  GCCTACTGAA  ATTCTGGCCC  AAGACCTGTA  GTCAAAAAGA  GGTCATGTTT  960
961   CTAGGGGAAA  TCGAGGAGAT  CCTGGACGTT  ATTGAGCCCA  CGCAGTTCAA  GAAAATTCAA  1020
1021  GAGCCTTTAT  TTAAGCAAAT  CGCTAAATGT  GTAGCCAGCC  CTCATTTTCA  GGTAGCAGAG  1080
1081  CGAGCGCTGT  ACTATTGGAA  CAATGAGTAT  ATTTTGAGTC  TAATCGAGGA  GAATAATGCC  1140
1141  AAAATCTTTC  CCATCATGTT  CGGAAACTTG  TACCGGATCT  CCAAAGAGCA  CTGGAACCCG  1200
1201  ACAATTGTGG  CGCTGGTGTA  TAATGTGTTA  AAAACCATGA  TGGAGATGAA  CAGCAAACTC  1260
1261  TTTGATGAGT  TGACGACTTC  ATACAAGTCT  GACAGACAGC  GAGAGAAGAA  GAAAGAGCAG  1320
1321  GAGCGTGAGG  AACTGTGGAG  GAGATTGGAT  GAACTGAGAA  TGAAAGAGGT  GTTGATGATC  1380
1381  CAGAACAACA  GACACGACAT  CCAGTTCACT  TACAACAACA  ACAACCACCA  TTAG  1434

▼ ANNOTATION

Disorder
D2P2IUPred2A
Interaction
MIST
Physicochemical
AAindex

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Mea-1457Mesocricetus auratus89.780.0 545
LLPS-Ten-0142Tetraodon nigroviridis88.40.0 740
LLPS-Caf-0673Canis familiaris88.140.0 609
LLPS-Scf-2206Scleropages formosus87.830.0 671
LLPS-Loa-1889Loxodonta africana87.070.0 648
LLPS-Leo-2944Lepisosteus oculatus87.010.0 728
LLPS-Sah-0331Sarcophilus harrisii86.540.0 644
LLPS-Fud-1201Fukomys damarensis86.240.0 637
LLPS-Orn-3556Oreochromis niloticus86.110.0 738
LLPS-Tar-2295Takifugu rubripes86.050.0 734
LLPS-Scm-2272Scophthalmus maximus85.470.0 737
LLPS-Sus-1058Sus scrofa85.380.0 706
LLPS-Bot-1783Bos taurus85.380.0 705
LLPS-Tut-1008Tursiops truncatus85.380.0 706
LLPS-Ova-0059Ovis aries85.380.0 705
LLPS-Asm-3403Astyanax mexicanus85.260.0 736
LLPS-Fec-0031Felis catus85.180.0 705
LLPS-Mup-2005Mustela putorius furo85.140.0 703
LLPS-Aim-1607Ailuropoda melanoleuca85.140.0 704
LLPS-Otg-0595Otolemur garnettii85.140.0 705
LLPS-Urm-2166Ursus maritimus85.110.0 699
LLPS-Aon-0832Aotus nancymaae84.910.0 701
LLPS-Gog-1756Gorilla gorilla84.910.0 701
LLPS-Myl-0205Myotis lucifugus84.910.0 700
LLPS-Pat-0881Pan troglodytes84.910.0 701
LLPS-Pap-0564Pan paniscus84.910.0 701
LLPS-Hos-2244Homo sapiens84.910.0 701
LLPS-Poa-2852Pongo abelii84.910.0 701
LLPS-Eqc-1757Equus caballus84.910.0 698
LLPS-Nol-0143Nomascus leucogenys84.910.0 701
LLPS-Anp-1684Anas platyrhynchos84.880.0 712
LLPS-Cea-3275Cercocebus atys84.670.0 700
LLPS-Maf-1180Macaca fascicularis84.670.0 700
LLPS-Chs-0821Chlorocebus sabaeus84.670.0 700
LLPS-Paa-1909Papio anubis84.670.0 700
LLPS-Man-0789Macaca nemestrina84.670.0 700
LLPS-Mam-0240Macaca mulatta84.670.0 700
LLPS-Ict-0283Ictidomys tridecemlineatus84.670.0 700
LLPS-Tag-0516Taeniopygia guttata84.650.0 708
LLPS-Mal-0244Mandrillus leucophaeus84.450.0 709
LLPS-Caj-2078Callithrix jacchus84.430.0 697
LLPS-Orc-0934Oryctolagus cuniculus84.430.0 698
LLPS-Fia-1623Ficedula albicollis84.420.0 707
LLPS-Cap-1203Cavia porcellus84.20.0 696
LLPS-Ran-3212Rattus norvegicus84.190.0 705
LLPS-Ora-2045Ornithorhynchus anatinus83.950.0 694
LLPS-Gaa-0005Gasterosteus aculeatus83.920.0 734
LLPS-Cas-3776Carlito syrichta83.740.0 672
LLPS-Mod-3649Monodelphis domestica83.730.0 693
LLPS-Pes-3706Pelodiscus sinensis83.720.0 694
LLPS-Orl-3347Oryzias latipes83.550.0 722
LLPS-Gaga-0999Gallus gallus83.490.0 693
LLPS-Xim-0352Xiphophorus maculatus83.480.0 722
LLPS-Mum-3727Mus musculus82.660.0 708
LLPS-Pof-0139Poecilia formosa82.480.0 720
LLPS-Meg-3091Meleagris gallopavo82.440.0 666
LLPS-Icp-2096Ictalurus punctatus82.070.0 687
LLPS-Drm-1199Drosophila melanogaster81.490.0 608
LLPS-Anc-2398Anolis carolinensis80.140.0 647
LLPS-Rhb-4776Rhinopithecus bieti77.590.0 646
LLPS-Xet-3755Xenopus tropicalis75.470.0 622
LLPS-Lac-3334Latimeria chalumnae74.770.0 614
LLPS-Dio-2377Dipodomys ordii70.50.0 549
LLPS-Cae-0025Caenorhabditis elegans68.160.0 566
LLPS-Cii-0726Ciona intestinalis66.430.0 533
LLPS-Mel-0192Melampsora laricipopulina61.441e-164 492
LLPS-Phn-1268Phaeosphaeria nodorum60.06e-162 481
LLPS-Lem-1458Leptosphaeria maculans59.755e-160 479
LLPS-Tum-1381Tuber melanosporum59.711e-161 480
LLPS-Usm-0679Ustilago maydis59.616e-163 486
LLPS-Cogr-0646Colletotrichum graminicola59.437e-166 491
LLPS-Ved-0893Verticillium dahliae59.436e-167 492
LLPS-Coo-0735Colletotrichum orbiculare59.193e-165 490
LLPS-Crn-1474Cryptococcus neoformans59.144e-165 491
LLPS-Mao-0286Magnaporthe oryzae58.957e-164 486
LLPS-Abg-0932Absidia glauca58.897e-160 474
LLPS-Pyt-0741Pyrenophora teres58.752e-162 482
LLPS-Fuv-0269Fusarium verticillioides58.716e-165 488
LLPS-Asn-0778Aspergillus nidulans58.715e-165 488
LLPS-Nec-0026Neurospora crassa58.711e-164 488
LLPS-Nef-0449Neosartorya fischeri58.711e-163 488
LLPS-Fus-1121Fusarium solani58.717e-165 488
LLPS-Fuo-0538Fusarium oxysporum58.713e-165 489
LLPS-Asfu-1465Aspergillus fumigatus58.711e-164 488
LLPS-Pug-0883Puccinia graminis58.624e-162 484
LLPS-Beb-1557Beauveria bassiana58.472e-163 484
LLPS-Trr-0867Trichoderma reesei58.471e-164 487
LLPS-Zyt-0778Zymoseptoria tritici58.351e-165 486
LLPS-Dos-0788Dothistroma septosporum58.351e-164 488
LLPS-Cis-0238Ciona savignyi58.246e-152 452
LLPS-Aso-0959Aspergillus oryzae58.237e-163 483
LLPS-Asf-1064Aspergillus flavus58.234e-164 483
LLPS-Ast-1097Aspergillus terreus58.231e-163 484
LLPS-Trv-0008Trichoderma virens58.15e-162 480
LLPS-Asc-0438Aspergillus clavatus58.02e-163 486
LLPS-Blg-0449Blumeria graminis58.07e-163 483
LLPS-Gag-1425Gaeumannomyces graminis57.867e-158 471
LLPS-Map-0754Magnaporthe poae57.862e-158 472
LLPS-Miv-1418Microbotryum violaceum57.772e-163 488
LLPS-Spr-0068Sporisorium reilianum57.771e-162 485
LLPS-Asni-0413Aspergillus niger57.527e-160 473
LLPS-Cog-1305Colletotrichum gloeosporioides57.185e-157 468
LLPS-Pytr-1574Pyrenophora triticirepentis56.715e-160 475
LLPS-Scj-1519Schizosaccharomyces japonicus56.419e-148 441
LLPS-Yal-0155Yarrowia lipolytica56.136e-155 467
LLPS-Phv-0229Phaseolus vulgaris55.357e-144 429
LLPS-Amt-1723Amborella trichopoda54.431e-142 427
LLPS-Nia-0963Nicotiana attenuata54.314e-141 422
LLPS-Zem-0598Zea mays54.312e-141 426
LLPS-Sol-0025Solanum lycopersicum54.296e-141 422
LLPS-Coc-2044Corchorus capsularis54.054e-141 422
LLPS-Orbr-2055Oryza brachyantha53.982e-142 426
LLPS-Mae-0165Manihot esculenta53.923e-141 423
LLPS-Scc-1405Schizosaccharomyces cryophilus53.797e-150 446
LLPS-Pot-0575Populus trichocarpa53.672e-141 424
LLPS-Hea-2265Helianthus annuus53.626e-144 430
LLPS-Sei-1991Setaria italica53.483e-145 432
LLPS-Thc-1287Theobroma cacao53.471e-141 424
LLPS-Brd-1627Brachypodium distachyon53.472e-141 423
LLPS-Php-2074Physcomitrella patens53.443e-143 428
LLPS-Prp-2036Prunus persica53.422e-141 423
LLPS-Scp-0033Schizosaccharomyces pombe53.323e-147 439
LLPS-Ori-1567Oryza indica52.582e-143 428
LLPS-Ors-1336Oryza sativa52.582e-143 428
LLPS-Org-0469Oryza glaberrima52.582e-143 428