• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Asfu-1465
AFUA_5G02560

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit
Gene Name: AFUA_5G02560
Ensembl Gene: AFUA_5G02560
Ensembl Protein: EAL86048
Organism: Aspergillus fumigatus
Taxa ID: 330879
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole body, OthersPredicted from orthologs(View)

▼ FUNCTION

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblEAL86048EAL86048
UniProtQ4WEC9, Q4WEC9_ASPFU
GeneBankAAHF01000011EAL86048.1
RefSeqXM_742993.1XP_748086.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MIAASAPPPP  RLGRLATTTA  LRYDKSLANI  TIQHEQLSRA  KEANKSSKKK  DSQNQAALAS  60
61    HQAQQSASPN  HGTPTSSTTS  VNDIRGKSPD  NATQAGVYPA  GQHYIPHGAG  VAGQPVNNGP  120
121   GTPTKQGQPI  APSVIISPSA  PPHVPPPGAA  ETMPGDLAPP  RKSHVFDRLQ  TTPKDMSEGI  180
181   RTPKRQHSSR  FDISDQRQRE  LEKLPGFHEV  PPNRRQELFM  QKIDQCNIIF  DFNDPTADMK  240
241   SKEIKRLALH  ELLDYVANNR  SVITEPMYPR  VVEMFAKNLF  RPIPPPVTPQ  GEAFDPEEDE  300
301   PVLEVAWPHI  QVVYEFFLRF  IESQDFNTNI  AKAYIDHHFV  LQLLELFDSE  DPRERDFLKT  360
361   TLHRIYGKFL  NLRSYIRRSI  NNVFFQFTYE  TERFNGIAEL  LEILGSIING  FALPLKEEHK  420
421   LFLTRVLLPL  HKVKSLSMYH  PQLAYCIVQF  LEKDSTLTKE  VVMGLLRYWP  KTNSTKEVMY  480
481   LNEVEDIFEV  MDPAEFAKVQ  VPLFQQLAKS  VASPHFQVAE  RALYFWNNEY  FCNLVSDNVE  540
541   TILPIMFAPL  YENSKGHWNR  TIHSMVYNAM  KMFMEINPQL  FDECSHEYNE  RQNSAEQREK  600
601   SRQERWEKVL  ERAKQRKNGL  LPPPAPPAEV  PAQVDEVDAL  AQDNQKRLNA  LKLEDSASNK  660
661   ERKEGATATV  SSILP  675
Nucleotide CDS Sequence (FASTA)
1     ATGATCGCCG  CCTCCGCCCC  CCCCCCCCCC  CGCCTTGGAC  GCCTGGCGAC  CACCACAGCA  60
61    CTGCGGTACG  ACAAGTCCCT  GGCTAATATA  ACTATTCAGC  ATGAGCAGTT  GTCGAGGGCA  120
121   AAAGAAGCGA  ATAAGTCCTC  GAAGAAGAAA  GACTCCCAGA  ACCAGGCCGC  CCTCGCCTCT  180
181   CACCAGGCCC  AGCAATCTGC  CTCCCCGAAC  CACGGCACGC  CGACTTCATC  TACGACCTCC  240
241   GTAAATGATA  TAAGGGGAAA  GTCGCCGGAT  AATGCCACGC  AAGCGGGGGT  GTACCCCGCT  300
301   GGCCAGCATT  ATATCCCACA  CGGTGCAGGC  GTCGCTGGAC  AACCTGTGAA  CAATGGACCG  360
361   GGGACTCCGA  CCAAGCAAGG  GCAGCCGATT  GCACCTAGCG  TTATCATCAG  CCCAAGCGCA  420
421   CCACCGCATG  TCCCCCCCCC  TGGTGCCGCA  GAGACGATGC  CTGGCGACTT  GGCTCCTCCG  480
481   AGAAAATCCC  ATGTCTTTGA  TCGCCTCCAG  ACTACACCCA  AGGATATGTC  GGAAGGGATT  540
541   CGGACTCCAA  AGCGTCAGCA  TTCGTCACGA  TTCGATATCT  CCGATCAGCG  CCAACGGGAG  600
601   CTGGAGAAAC  TTCCCGGATT  CCACGAAGTG  CCACCGAATC  GGCGCCAAGA  GCTTTTCATG  660
661   CAGAAGATTG  ACCAGTGCAA  TATCATTTTC  GACTTCAATG  ATCCTACAGC  CGACATGAAG  720
721   TCCAAGGAGA  TCAAGAGACT  GGCGCTCCAC  GAGCTCCTAG  ACTACGTGGC  GAACAACCGT  780
781   TCAGTAATCA  CCGAACCCAT  GTACCCTCGA  GTGGTCGAGA  TGTTCGCCAA  AAACCTCTTT  840
841   CGACCCATCC  CTCCCCCGGT  TACCCCCCAA  GGCGAGGCCT  TTGATCCGGA  AGAGGATGAG  900
901   CCGGTCCTGG  AAGTGGCCTG  GCCACATATC  CAGGTTGTAT  ATGAGTTCTT  CTTGAGATTT  960
961   ATCGAGAGTC  AGGATTTCAA  CACCAACATC  GCCAAGGCAT  ATATCGATCA  TCATTTTGTC  1020
1021  CTCCAGTTAT  TGGAGTTATT  CGATTCGGAA  GACCCTCGCG  AACGGGACTT  TCTCAAGACC  1080
1081  ACATTGCACC  GGATCTACGG  AAAGTTTCTG  AATCTGCGGT  CTTATATCCG  TCGATCCATC  1140
1141  AACAACGTTT  TCTTCCAATT  CACGTACGAG  ACTGAGCGCT  TCAACGGAAT  AGCCGAGTTG  1200
1201  TTAGAAATTC  TGGGGTCTAT  CATCAACGGA  TTTGCCTTGC  CTCTGAAGGA  GGAGCATAAG  1260
1261  CTCTTTCTGA  CCCGAGTGCT  GCTCCCCTTG  CACAAAGTCA  AGAGTCTCAG  CATGTATCAC  1320
1321  CCACAACTCG  CGTATTGTAT  CGTCCAATTC  CTTGAAAAGG  ATTCTACCTT  GACTAAAGAG  1380
1381  GTCGTCATGG  GCTTGCTACG  CTACTGGCCT  AAGACGAACA  GCACCAAGGA  GGTCATGTAT  1440
1441  CTCAACGAAG  TGGAAGATAT  CTTCGAAGTC  ATGGATCCAG  CAGAATTTGC  CAAGGTGCAA  1500
1501  GTACCTCTTT  TCCAACAACT  GGCCAAGTCA  GTTGCAAGTC  CTCATTTCCA  GGTCGCGGAA  1560
1561  CGCGCACTCT  ACTTCTGGAA  CAATGAATAT  TTCTGCAACT  TAGTCAGTGA  CAATGTGGAG  1620
1621  ACGATCCTTC  CCATCATGTT  CGCGCCGCTT  TACGAGAATT  CCAAGGGTCA  TTGGAATCGA  1680
1681  ACAATCCATA  GCATGGTGTA  CAACGCCATG  AAGATGTTCA  TGGAAATCAA  CCCTCAACTG  1740
1741  TTCGACGAAT  GTTCCCACGA  ATATAATGAG  CGACAGAACA  GCGCCGAGCA  GCGTGAGAAA  1800
1801  TCTCGACAGG  AGCGATGGGA  GAAGGTCTTG  GAGCGAGCCA  AGCAAAGGAA  AAACGGACTC  1860
1861  TTACCTCCTC  CAGCTCCGCC  TGCAGAAGTG  CCAGCGCAAG  TTGATGAGGT  CGATGCTCTT  1920
1921  GCTCAGGATA  ACCAGAAGCG  TCTCAACGCC  CTGAAACTGG  AGGACTCTGC  GTCAAACAAG  1980
1981  GAGCGGAAAG  AGGGTGCAAC  AGCTACCGTA  AGTAGCATCC  TACCGTGA  2028

▼ KEYWORD

ID
Family
Coiled coil
Complete proteome
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytosol
Cellular Component
Nucleus
Cellular Component
Protein phosphatase type 2A complex
Molecular Function
Protein phosphatase activator activity
Biological Process
Protein dephosphorylation
Biological Process
Regulation of protein autophosphorylation
Biological Process
Signal transduction

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Nef-0449Neosartorya fischeri98.590.01196
LLPS-Asf-1064Aspergillus flavus92.530.0 978
LLPS-Asc-0438Aspergillus clavatus89.810.01115
LLPS-Asni-0413Aspergillus niger89.590.01002
LLPS-Aso-0959Aspergillus oryzae89.270.01082
LLPS-Zyt-0778Zymoseptoria tritici87.710.0 865
LLPS-Asn-0778Aspergillus nidulans83.830.01033
LLPS-Tum-1381Tuber melanosporum83.790.0 837
LLPS-Ast-1097Aspergillus terreus83.720.01055
LLPS-Lem-1458Leptosphaeria maculans83.490.0 902
LLPS-Coo-0735Colletotrichum orbiculare83.330.0 900
LLPS-Ved-0893Verticillium dahliae79.820.0 889
LLPS-Dos-0788Dothistroma septosporum77.340.0 882
LLPS-Pyt-0741Pyrenophora teres76.590.0 924
LLPS-Mao-0286Magnaporthe oryzae76.340.0 890
LLPS-Pytr-1574Pyrenophora triticirepentis76.10.0 906
LLPS-Phn-1268Phaeosphaeria nodorum76.040.0 927
LLPS-Cogr-0646Colletotrichum graminicola74.720.0 910
LLPS-Cog-1305Colletotrichum gloeosporioides74.070.0 881
LLPS-Nec-0026Neurospora crassa73.660.0 889
LLPS-Fuv-0269Fusarium verticillioides73.540.0 875
LLPS-Trv-0008Trichoderma virens73.280.0 875
LLPS-Fus-1121Fusarium solani73.210.0 883
LLPS-Trr-0867Trichoderma reesei73.070.0 878
LLPS-Map-0754Magnaporthe poae72.930.0 879
LLPS-Beb-1557Beauveria bassiana72.770.0 853
LLPS-Gag-1425Gaeumannomyces graminis72.70.0 879
LLPS-Fuo-0538Fusarium oxysporum71.70.0 874
LLPS-Blg-0449Blumeria graminis68.910.0 845
LLPS-Yal-0155Yarrowia lipolytica68.670.0 693
LLPS-Fec-4708Felis catus67.730.0 596
LLPS-Poa-0381Pongo abelii67.320.0 595
LLPS-Ict-3216Ictidomys tridecemlineatus67.320.0 595
LLPS-Loa-2160Loxodonta africana67.320.0 594
LLPS-Hos-4558Homo sapiens67.320.0 597
LLPS-Otg-4019Otolemur garnettii67.320.0 594
LLPS-Dio-2377Dipodomys ordii67.320.0 595
LLPS-Myl-4224Myotis lucifugus67.320.0 597
LLPS-Mup-2908Mustela putorius furo67.320.0 594
LLPS-Ora-2842Ornithorhynchus anatinus67.320.0 589
LLPS-Fud-1969Fukomys damarensis67.320.0 595
LLPS-Cas-2504Carlito syrichta67.240.0 597
LLPS-Xim-3509Xiphophorus maculatus67.230.0 603
LLPS-Ova-0785Ovis aries67.080.0 592
LLPS-Mum-4712Mus musculus67.080.0 594
LLPS-Cap-3226Cavia porcellus67.070.0 607
LLPS-Pof-2176Poecilia formosa66.910.0 608
LLPS-Lac-1637Latimeria chalumnae66.830.0 610
LLPS-Sus-3352Sus scrofa66.830.0 595
LLPS-Ran-3231Rattus norvegicus66.440.0 620
LLPS-Gaga-3318Gallus gallus66.280.0 616
LLPS-Leo-1544Lepisosteus oculatus66.280.0 617
LLPS-Gaa-1896Gasterosteus aculeatus66.260.0 592
LLPS-Meg-1862Meleagris gallopavo66.130.0 612
LLPS-Anp-2272Anas platyrhynchos65.830.0 610
LLPS-Sah-1872Sarcophilus harrisii65.830.0 617
LLPS-Pug-0883Puccinia graminis65.680.0 636
LLPS-Miv-1418Microbotryum violaceum65.470.0 649
LLPS-Orn-2675Oreochromis niloticus65.380.0 615
LLPS-Usm-0679Ustilago maydis65.330.0 668
LLPS-Scf-3430Scleropages formosus65.220.0 625
LLPS-Orl-0160Oryzias latipes65.220.0 618
LLPS-Icp-2962Ictalurus punctatus65.220.0 622
LLPS-Dar-2286Danio rerio65.120.0 627
LLPS-Anc-3050Anolis carolinensis64.990.0 622
LLPS-Asm-3373Astyanax mexicanus64.930.0 626
LLPS-Crn-1474Cryptococcus neoformans64.380.0 632
LLPS-Tar-2641Takifugu rubripes64.30.0 613
LLPS-Pes-0597Pelodiscus sinensis64.240.0 611
LLPS-Tag-1420Taeniopygia guttata64.220.0 618
LLPS-Fia-3524Ficedula albicollis64.220.0 618
LLPS-Mam-2781Macaca mulatta63.970.0 622
LLPS-Caf-2474Canis familiaris63.970.0 621
LLPS-Eqc-0260Equus caballus63.970.0 626
LLPS-Nol-2738Nomascus leucogenys63.970.0 623
LLPS-Pap-1949Pan paniscus63.970.0 623
LLPS-Pat-2369Pan troglodytes63.970.0 623
LLPS-Mal-4678Mandrillus leucophaeus63.970.0 622
LLPS-Cea-3165Cercocebus atys63.970.0 623
LLPS-Aon-3781Aotus nancymaae63.970.0 621
LLPS-Maf-4313Macaca fascicularis63.970.0 623
LLPS-Chs-3750Chlorocebus sabaeus63.970.0 623
LLPS-Caj-1955Callithrix jacchus63.970.0 623
LLPS-Gog-3585Gorilla gorilla63.970.0 623
LLPS-Man-3134Macaca nemestrina63.760.0 611
LLPS-Rhb-4277Rhinopithecus bieti63.760.0 611
LLPS-Bot-2810Bos taurus63.760.0 612
LLPS-Paa-1731Papio anubis63.760.0 611
LLPS-Aim-0873Ailuropoda melanoleuca63.760.0 613
LLPS-Mea-4018Mesocricetus auratus63.760.0 612
LLPS-Scm-0572Scophthalmus maximus63.430.0 614
LLPS-Mel-0192Melampsora laricipopulina63.360.0 633
LLPS-Mod-1613Monodelphis domestica63.30.0 604
LLPS-Tut-0555Tursiops truncatus63.30.0 620
LLPS-Kop-0965Komagataella pastoris63.271e-175 523
LLPS-Urm-4011Ursus maritimus63.150.0 611
LLPS-Cii-0726Ciona intestinalis63.010.0 605
LLPS-Scj-0959Schizosaccharomyces japonicus62.690.0 617
LLPS-Abg-0932Absidia glauca62.470.0 630
LLPS-Orc-2816Oryctolagus cuniculus62.450.0 622
LLPS-Scp-0033Schizosaccharomyces pombe61.660.0 565
LLPS-Scc-1405Schizosaccharomyces cryophilus61.520.0 565
LLPS-Spr-0068Sporisorium reilianum61.380.0 667
LLPS-Xet-3755Xenopus tropicalis60.914e-174 512
LLPS-Sac-0179Saccharomyces cerevisiae60.620.0 605
LLPS-Drm-1199Drosophila melanogaster60.330.0 541
LLPS-Ten-0723Tetraodon nigroviridis59.470.0 614
LLPS-Asg-0684Ashbya gossypii59.040.0 613
LLPS-Cae-0025Caenorhabditis elegans57.922e-179 529
LLPS-Put-1350Puccinia triticina57.490.0 542
LLPS-Cis-0238Ciona savignyi55.536e-173 513
LLPS-Pot-0575Populus trichocarpa53.461e-163 488
LLPS-Mae-0165Manihot esculenta53.468e-161 480
LLPS-Coc-0860Corchorus capsularis53.383e-159 476
LLPS-Nia-0963Nicotiana attenuata53.112e-163 487
LLPS-Php-2074Physcomitrella patens52.862e-161 483
LLPS-Prp-2036Prunus persica52.763e-160 479
LLPS-Viv-0534Vitis vinifera52.762e-159 477
LLPS-Cus-0807Cucumis sativus52.765e-160 479
LLPS-Glm-0631Glycine max52.525e-160 478
LLPS-Thc-1287Theobroma cacao52.392e-159 477
LLPS-Sot-0075Solanum tuberosum52.059e-159 474
LLPS-Sei-1991Setaria italica48.954e-162 483
LLPS-Sol-0025Solanum lycopersicum48.941e-160 480