• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Cii-1862
LOC100177393

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: Adenylate kinase isoenzyme 6 homolog
Gene Name: LOC100177393
Ensembl Gene: ENSCING00000008938.3
Ensembl Protein: ENSCINP00000018158.3
Organism: Ciona intestinalis
Taxa ID: 7719
LLPS Type: Client


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ FUNCTION


Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity.

▼ CROSS REFERENCE


▼ SEQUENCE


Protein Sequence (FASTA)
1     MRVKPNILIS  GTPGTGKTTL  AQELANVTNL  NFVSIGQIAK  ENELFCGYDD  QLQCPILDEE  60
61    RVLDELEEQM  SEGGNIVDYH  GCEFFPQRWF  DIVFVLRTDN  TILHERLSQR  GYNEMKLKNN  120
121   IESEIFQIIL  DEARESYDEQ  IVHELESNTP  ENMEKNIEQI  VVWVNQWSTP  AD  172
Nucleotide CDS Sequence (FASTA)
1     ATGAGAGTAA  AACCGAATAT  TTTGATTTCT  GGGACACCAG  GAACTGGTAA  GACGACATTG  60
61    GCACAAGAAC  TGGCAAATGT  TACTAACCTC  AACTTTGTAA  GCATTGGACA  AATTGCAAAG  120
121   GAAAACGAAT  TGTTCTGTGG  TTATGATGAT  CAATTGCAAT  GTCCCATTCT  GGATGAAGAA  180
181   AGAGTACTGG  ATGAACTTGA  AGAGCAAATG  AGTGAAGGAG  GTAATATAGT  GGATTATCAT  240
241   GGCTGTGAAT  TCTTTCCACA  AAGGTGGTTT  GACATTGTCT  TTGTATTACG  CACTGATAAC  300
301   ACCATTTTGC  ATGAAAGATT  ATCACAAAGA  GGATATAATG  AGATGAAGCT  AAAAAATAAT  360
361   ATTGAATCTG  AAATATTTCA  AATCATTCTT  GACGAAGCAC  GCGAGTCTTA  TGATGAACAA  420
421   ATTGTACATG  AACTTGAGAG  TAACACCCCT  GAAAATATGG  AAAAAAATAT  TGAACAAATA  480
481   GTTGTGTGGG  TAAACCAGTG  GTCAACCCCT  GCTGACTGA  519

▼ KEYWORD


ID
Family
ATP-binding
Complete proteome
Kinase
Nucleotide-binding
Nucleus
Reference proteome
Transferase

▼ GENE ONTOLOGY


ID
Classification
Description
Cellular Component
Cytoplasm
Cellular Component
Nucleus
Molecular Function
Adenylate kinase activity
Molecular Function
ATP binding
Molecular Function
ATPase activity

▼ KEGG



▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Fud-3467Fukomys damarensis63.641e-67 210
LLPS-Lac-2676Latimeria chalumnae63.411e-67 210
LLPS-Orn-2081Oreochromis niloticus63.258e-68 211
LLPS-Eqc-1324Equus caballus63.197e-68 212
LLPS-Myl-2484Myotis lucifugus62.585e-67 209
LLPS-Ova-1954Ovis aries62.582e-67 209
LLPS-Ten-3731Tetraodon nigroviridis62.53e-68 212
LLPS-Xet-2358Xenopus tropicalis62.59e-61 193
LLPS-Dar-2416Danio rerio62.132e-67 210
LLPS-Fec-2200Felis catus61.962e-67 209
LLPS-Ran-3754Rattus norvegicus61.965e-65 204
LLPS-Gaa-0532Gasterosteus aculeatus61.681e-68 213
LLPS-Asm-1831Astyanax mexicanus61.594e-67 209
LLPS-Cap-3242Cavia porcellus61.351e-65 205
LLPS-Ict-4050Ictidomys tridecemlineatus61.351e-65 205
LLPS-Aon-1520Aotus nancymaae61.351e-66 208
LLPS-Caj-2413Callithrix jacchus61.351e-66 208
LLPS-Aim-4307Ailuropoda melanoleuca61.352e-66 207
LLPS-Mup-2037Mustela putorius furo61.355e-67 209
LLPS-Loa-4312Loxodonta africana61.252e-63 200
LLPS-Sus-2790Sus scrofa61.155e-63 199
LLPS-Leo-1628Lepisosteus oculatus60.986e-65 204
LLPS-Scf-4078Scleropages formosus60.985e-66 206
LLPS-Dio-3986Dipodomys ordii60.981e-66 207
LLPS-Mea-4194Mesocricetus auratus60.92e-47 157
LLPS-Tar-1733Takifugu rubripes60.656e-59 187
LLPS-Urm-2549Ursus maritimus60.499e-64 202
LLPS-Bot-4240Bos taurus60.492e-62 200
LLPS-Icp-0112Ictalurus punctatus60.363e-66 207
LLPS-Hos-4180Homo sapiens60.121e-65 205
LLPS-Pat-3854Pan troglodytes60.121e-65 205
LLPS-Pap-3103Pan paniscus60.121e-65 205
LLPS-Rhb-2807Rhinopithecus bieti60.121e-65 205
LLPS-Orc-3214Oryctolagus cuniculus60.123e-65 204
LLPS-Poa-2369Pongo abelii60.121e-65 205
LLPS-Nol-0874Nomascus leucogenys60.121e-65 205
LLPS-Maf-0259Macaca fascicularis60.121e-65 205
LLPS-Mal-4631Mandrillus leucophaeus60.121e-65 205
LLPS-Paa-0410Papio anubis60.121e-65 205
LLPS-Orl-3209Oryzias latipes59.888e-65 203
LLPS-Chs-2386Chlorocebus sabaeus59.878e-62 195
LLPS-Tag-1676Taeniopygia guttata59.622e-59 189
LLPS-Anc-1606Anolis carolinensis59.516e-65 204
LLPS-Meg-1637Meleagris gallopavo59.499e-60 190
LLPS-Cea-4312Cercocebus atys59.496e-62 196
LLPS-Gaga-0097Gallus gallus59.395e-65 203
LLPS-Mam-2872Macaca mulatta59.262e-62 197
LLPS-Pes-0512Pelodiscus sinensis59.153e-64 202
LLPS-Man-3929Macaca nemestrina59.123e-62 197
LLPS-Otg-0771Otolemur garnettii58.92e-63 199
LLPS-Sah-1480Sarcophilus harrisii58.95e-61 193
LLPS-Pof-1575Poecilia formosa58.686e-64 201
LLPS-Xim-2502Xiphophorus maculatus58.688e-65 203
LLPS-Fia-3080Ficedula albicollis58.544e-64 201
LLPS-Anp-1214Anas platyrhynchos58.283e-61 194
LLPS-Met-1914Medicago truncatula58.081e-49 167
LLPS-Gog-2279Gorilla gorilla57.998e-63 198
LLPS-Mod-0577Monodelphis domestica57.499e-62 195
LLPS-Cus-2257Cucumis sativus57.231e-49 164
LLPS-Phv-0744Phaseolus vulgaris56.86e-52 170
LLPS-Pot-0442Populus trichocarpa56.213e-50 166
LLPS-Hea-1467Helianthus annuus56.145e-52 170
LLPS-Gor-0462Gossypium raimondii56.023e-52 171
LLPS-Vir-2019Vigna radiata55.951e-47 162
LLPS-Nia-1991Nicotiana attenuata55.693e-50 166
LLPS-Sot-0622Solanum tuberosum55.693e-49 163
LLPS-Thc-1463Theobroma cacao55.427e-50 165
LLPS-Mae-0972Manihot esculenta55.291e-48 162
LLPS-Via-1421Vigna angularis55.296e-51 168
LLPS-Dac-2417Daucus carota55.092e-48 161
LLPS-Orp-1104Oryza punctata54.821e-49 164
LLPS-Viv-0308Vitis vinifera54.712e-49 164
LLPS-Glm-2863Glycine max54.716e-52 170
LLPS-Art-2564Arabidopsis thaliana54.222e-61 195
LLPS-Sob-1672Sorghum bicolor54.222e-48 163
LLPS-Coc-0439Corchorus capsularis54.221e-48 162
LLPS-Zem-1420Zea mays54.225e-48 160
LLPS-Lep-1201Leersia perrieri54.225e-49 163
LLPS-Sei-1470Setaria italica54.221e-48 162
LLPS-Arl-0507Arabidopsis lyrata54.193e-43 152
LLPS-Ors-2033Oryza sativa53.612e-48 161
LLPS-Orr-1744Oryza rufipogon53.619e-49 162
LLPS-Org-0699Oryza glaberrima53.613e-48 160
LLPS-Ori-1478Oryza indica53.619e-49 162
LLPS-Orb-1255Oryza barthii53.613e-48 160
LLPS-Orni-2232Oryza nivara53.611e-47 161
LLPS-Mua-0988Musa acuminata53.615e-48 160
LLPS-Orgl-1539Oryza glumaepatula53.619e-49 162
LLPS-Tru-1316Triticum urartu53.372e-46 156
LLPS-Tra-2238Triticum aestivum53.371e-46 157
LLPS-Prp-1779Prunus persica53.291e-48 162
LLPS-Bro-0532Brassica oleracea53.295e-56 186
LLPS-Orbr-2272Oryza brachyantha53.258e-49 162
LLPS-Brd-1179Brachypodium distachyon53.252e-48 161
LLPS-Php-2386Physcomitrella patens51.852e-52 172
LLPS-Brr-1330Brassica rapa51.814e-56 181
LLPS-Brn-0347Brassica napus51.818e-56 180
LLPS-Sem-0741Selaginella moellendorffii50.65e-52 170
LLPS-Amt-0330Amborella trichopoda50.03e-44 151
LLPS-Put-0092Puccinia triticina50.04e-32 119
LLPS-Ved-0506Verticillium dahliae50.03e-52 171
LLPS-Scj-1350Schizosaccharomyces japonicus49.72e-49 164
LLPS-Pug-0592Puccinia graminis49.421e-32 122
LLPS-Sol-0385Solanum lycopersicum49.411e-39 139
LLPS-Pytr-0319Pyrenophora triticirepentis49.47e-46 155
LLPS-Scp-0844Schizosaccharomyces pombe49.12e-42 146
LLPS-Scs-1128Sclerotinia sclerotiorum48.816e-52 170
LLPS-Pyt-1002Pyrenophora teres48.815e-45 152
LLPS-Abg-1967Absidia glauca48.487e-41 142
LLPS-Phn-0098Phaeosphaeria nodorum48.212e-47 159
LLPS-Cogr-1347Colletotrichum graminicola48.197e-51 167
LLPS-Scc-1554Schizosaccharomyces cryophilus48.191e-44 152
LLPS-Drm-0517Drosophila melanogaster48.198e-47 157
LLPS-Trr-1457Trichoderma reesei47.934e-49 163
LLPS-Cae-2042Caenorhabditis elegans47.937e-49 162
LLPS-Trv-0559Trichoderma virens47.92e-48 161
LLPS-Beb-1293Beauveria bassiana47.319e-44 149
LLPS-Cog-0942Colletotrichum gloeosporioides47.315e-50 165
LLPS-Blg-0496Blumeria graminis46.439e-48 159
LLPS-Map-0029Magnaporthe poae46.392e-47 159
LLPS-Gag-1432Gaeumannomyces graminis46.112e-48 162
LLPS-Lem-0164Leptosphaeria maculans46.04e-0750.4
LLPS-Asfu-0194Aspergillus fumigatus45.838e-44 149
LLPS-Mao-0651Magnaporthe oryzae45.782e-37 132
LLPS-Fus-1264Fusarium solani45.512e-47 159
LLPS-Ast-1149Aspergillus terreus45.292e-48 161
LLPS-Nef-0951Neosartorya fischeri45.249e-44 149
LLPS-Asc-1238Aspergillus clavatus45.242e-44 151
LLPS-Nec-1222Neurospora crassa45.181e-47 159
LLPS-Fuv-1396Fusarium verticillioides45.034e-46 155
LLPS-Zyt-0957Zymoseptoria tritici44.978e-42 145
LLPS-Coo-0012Colletotrichum orbiculare44.912e-40 140
LLPS-Chr-1316Chlamydomonas reinhardtii44.178e-35 126
LLPS-Asn-0696Aspergillus nidulans44.122e-44 151
LLPS-Yal-1350Yarrowia lipolytica43.451e-42 146
LLPS-Asg-0760Ashbya gossypii43.27e-38 135
LLPS-Fuo-1376Fusarium oxysporum43.126e-2292.0
LLPS-Kop-0803Komagataella pastoris42.443e-40 140
LLPS-Dos-0975Dothistroma septosporum42.353e-38 135
LLPS-Miv-0719Microbotryum violaceum42.229e-29 111
LLPS-Sac-0202Saccharomyces cerevisiae41.321e-35 129
LLPS-Gas-0892Galdieria sulphuraria40.884e-35 127
LLPS-Crn-1064Cryptococcus neoformans40.332e-29 112
LLPS-Mel-0169Melampsora laricipopulina38.691e-2192.4
LLPS-Tum-1628Tuber melanosporum38.698e-28 107
LLPS-Osl-1146Ostreococcus lucimarinus35.882e-30 114
LLPS-Cym-0932Cyanidioschyzon merolae33.932e-25 102
LLPS-Spr-1267Sporisorium reilianum31.222e-27 108
LLPS-Aso-0600Aspergillus oryzae29.946e-1675.1
LLPS-Usm-0966Ustilago maydis29.92e-27 107