LLPS-Cii-1520
LOC100182084
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Cell division control protein |
| Gene Name: | LOC100182084 |
| Ensembl Gene: | ENSCING00000001669.3 |
| Ensembl Protein: | ENSCINP00000003393.3 |
| Organism: | Ciona intestinalis |
| Taxa ID: | 7719 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Chromatin, Spindle apparatus | Predicted from orthologs | (View) |
▼ FUNCTION
| Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSCINT00000003393.3 | ENSCINP00000003393.3 |
| UniProt | F6X8B5, F6X8B5_CIOIN |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 SSPKRAISAP KTEVTSPNKK KKQDNEENEE NTPPVRSPKK SPKKVPQFGT RVVLLKNALH 60 61 NAAPKRLIGR ESELKEIEDF IEDLVETKKS GSLYISGAPG TGKSACLSQA LSDPKVTSKL 120 121 AQSISINCMS VRTASQIYQQ IATEMGANSK ESKSARTALK FIENDLTTRE SMILLLLDEM 180 181 DQLDSRNHEV LYTMFGWSAL PNSKVILIGI ANSLDLTDRI LPRLQARLEC KPKLLNFKPY 240 241 SKDQLANILQ ARISKASRGH DDIKVVDAMA VQFCARKIAA TSGDARKALD VCRRAVELVE 300 301 TNSLGNTAGE FLTGNTKFLL SESTTKVGIR QISSVMDGVY GNVYSSHGGA TEADDAFPLQ 360 361 QKLVVCSLLL LCKKTKSYEA PLGKLRETYT TICKDRQVSA VSQSEFHSLC DLVEARGLVS 420 421 LRRHKQPRLA KIKLNVDEKE IEFALKGKAL LSSILQRGIS K 461 |
| Nucleotide CDS Sequence (FASTA) |
1 TCTTCTCCCA AAAGAGCAAT TTCAGCTCCG AAAACAGAGG TTACATCTCC AAATAAAAAG 60 61 AAGAAACAAG ATAATGAAGA AAATGAGGAA AACACACCTC CAGTTCGATC TCCAAAAAAA 120 121 TCGCCGAAAA AAGTTCCCCA ATTTGGCACC CGCGTTGTTT TACTAAAGAA CGCTTTACAC 180 181 AACGCTGCTC CGAAGCGCTT GATTGGTCGA GAATCCGAAC TTAAGGAAAT TGAAGATTTT 240 241 ATCGAAGATT TGGTGGAGAC GAAAAAGTCT GGAAGTCTTT ATATTTCCGG AGCACCCGGG 300 301 ACTGGGAAGA GTGCTTGTCT CTCGCAAGCT TTGTCTGATC CAAAGGTGAC ATCGAAACTA 360 361 GCTCAATCTA TTTCCATCAA TTGTATGTCA GTACGCACGG CGTCACAAAT ATACCAACAA 420 421 ATTGCAACGG AAATGGGGGC CAACAGTAAG GAGTCAAAAT CTGCACGAAC AGCGCTCAAA 480 481 TTTATTGAAA ATGATCTTAC AACGCGAGAA TCTATGATCT TACTCCTCTT GGATGAGATG 540 541 GACCAGCTTG ACAGTCGTAA TCATGAAGTT CTTTACACAA TGTTTGGATG GTCAGCTCTT 600 601 CCTAATTCCA AAGTCATTCT GATCGGGATC GCCAACTCTC TAGATCTGAC CGACCGTATT 660 661 TTACCGAGAC TCCAAGCACG ATTAGAATGT AAACCAAAAC TTCTCAATTT TAAACCGTAC 720 721 AGCAAAGACC AGCTGGCTAA TATTTTACAA GCTCGTATTT CTAAGGCATC GCGTGGCCAC 780 781 GATGACATCA AGGTAGTCGA CGCAATGGCC GTTCAATTTT GCGCTCGTAA AATCGCTGCC 840 841 ACATCTGGAG ACGCTCGTAA AGCGCTCGAC GTTTGTCGTA GGGCTGTCGA ACTCGTAGAA 900 901 ACTAATTCTC TCGGCAACAC TGCTGGTGAG TTTTTAACTG GCAACACTAA ATTTTTGTTA 960 961 TCAGAATCAA CAACAAAAGT CGGAATTCGA CAAATCTCTT CAGTGATGGA CGGAGTTTAT 1020 1021 GGCAATGTTT ACTCGTCACA TGGTGGTGCC ACAGAGGCGG ACGATGCGTT TCCGTTACAA 1080 1081 CAAAAGTTGG TGGTGTGTTC GTTGCTACTA CTGTGCAAGA AAACGAAAAG TTACGAGGCT 1140 1141 CCTTTGGGAA AGCTTAGAGA AACATACACT ACAATATGCA AGGACAGACA AGTATCTGCA 1200 1201 GTAAGTCAAT CAGAATTTCA TTCCCTATGC GACCTTGTTG AAGCCAGAGG ACTTGTTTCA 1260 1261 TTACGTCGAC ATAAACAGCC ACGTCTTGCA AAGATCAAGT TAAATGTTGA TGAAAAAGAA 1320 1321 ATCGAATTTG CTTTAAAAGG AAAAGCACTT TTATCTTCTA TTCTCCAACG AGGAATTTCG 1380 1381 AAGTGA 1386 |
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Nucleus | |
Molecular Function | DNA replication origin binding | |
Biological Process | Cell division | |
Biological Process | DNA replication initiation | |
Biological Process | Mitotic cell cycle | |
Biological Process | Mitotic cell cycle phase transition | |
Biological Process | Mitotic DNA replication checkpoint |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Cis-1237 | Ciona savignyi | 68.7 | 0.0 | 525 |
| LLPS-Ora-3206 | Ornithorhynchus anatinus | 51.41 | 9e-77 | 251 |
| LLPS-Mea-3877 | Mesocricetus auratus | 50.97 | 1e-80 | 263 |
| LLPS-Xet-2228 | Xenopus tropicalis | 50.0 | 1e-120 | 370 |
| LLPS-Ran-1909 | Rattus norvegicus | 49.52 | 6e-115 | 356 |
| LLPS-Fec-3668 | Felis catus | 49.52 | 6e-112 | 348 |
| LLPS-Caf-0843 | Canis familiaris | 49.28 | 2e-114 | 355 |
| LLPS-Eqc-1433 | Equus caballus | 49.28 | 3e-113 | 352 |
| LLPS-Orc-4087 | Oryctolagus cuniculus | 49.28 | 4e-114 | 354 |
| LLPS-Gaa-0861 | Gasterosteus aculeatus | 49.24 | 9e-64 | 213 |
| LLPS-Dar-1998 | Danio rerio | 49.14 | 5e-110 | 343 |
| LLPS-Aim-0757 | Ailuropoda melanoleuca | 49.05 | 1e-111 | 347 |
| LLPS-Ova-2541 | Ovis aries | 48.8 | 1e-112 | 352 |
| LLPS-Urm-3093 | Ursus maritimus | 48.8 | 2e-112 | 349 |
| LLPS-Mum-2044 | Mus musculus | 48.79 | 2e-111 | 348 |
| LLPS-Gog-2728 | Gorilla gorilla | 48.67 | 3e-111 | 347 |
| LLPS-Anc-3928 | Anolis carolinensis | 48.66 | 4e-109 | 341 |
| LLPS-Asm-2820 | Astyanax mexicanus | 48.64 | 4e-108 | 339 |
| LLPS-Icp-1280 | Ictalurus punctatus | 48.64 | 2e-108 | 340 |
| LLPS-Bot-3024 | Bos taurus | 48.56 | 3e-112 | 350 |
| LLPS-Hos-4426 | Homo sapiens | 48.56 | 2e-111 | 347 |
| LLPS-Caj-3512 | Callithrix jacchus | 48.43 | 3e-110 | 343 |
| LLPS-Ict-3804 | Ictidomys tridecemlineatus | 48.43 | 4e-112 | 349 |
| LLPS-Pat-2667 | Pan troglodytes | 48.32 | 5e-111 | 346 |
| LLPS-Pap-2051 | Pan paniscus | 48.32 | 5e-111 | 346 |
| LLPS-Rhb-4474 | Rhinopithecus bieti | 48.31 | 1e-112 | 350 |
| LLPS-Aon-4411 | Aotus nancymaae | 48.08 | 3e-110 | 343 |
| LLPS-Cas-3855 | Carlito syrichta | 48.08 | 2e-111 | 347 |
| LLPS-Mal-1523 | Mandrillus leucophaeus | 48.07 | 1e-111 | 347 |
| LLPS-Maf-2057 | Macaca fascicularis | 48.07 | 2e-111 | 347 |
| LLPS-Mam-2310 | Macaca mulatta | 48.07 | 2e-111 | 347 |
| LLPS-Chs-4355 | Chlorocebus sabaeus | 47.96 | 3e-112 | 349 |
| LLPS-Tar-0817 | Takifugu rubripes | 47.89 | 1e-82 | 273 |
| LLPS-Sah-3084 | Sarcophilus harrisii | 47.85 | 3e-110 | 343 |
| LLPS-Myl-1809 | Myotis lucifugus | 47.84 | 6e-112 | 348 |
| LLPS-Sus-4789 | Sus scrofa | 47.84 | 9e-111 | 345 |
| LLPS-Poa-2036 | Pongo abelii | 47.84 | 6e-110 | 343 |
| LLPS-Paa-2958 | Papio anubis | 47.83 | 8e-111 | 345 |
| LLPS-Mup-0751 | Mustela putorius furo | 47.83 | 9e-110 | 342 |
| LLPS-Otg-2299 | Otolemur garnettii | 47.83 | 6e-107 | 335 |
| LLPS-Nol-1384 | Nomascus leucogenys | 47.72 | 9e-111 | 345 |
| LLPS-Fud-3695 | Fukomys damarensis | 47.57 | 2e-111 | 347 |
| LLPS-Scf-1097 | Scleropages formosus | 47.51 | 7e-106 | 332 |
| LLPS-Loa-2197 | Loxodonta africana | 47.34 | 2e-109 | 341 |
| LLPS-Leo-0155 | Lepisosteus oculatus | 47.32 | 2e-109 | 342 |
| LLPS-Scm-0103 | Scophthalmus maximus | 47.32 | 5e-109 | 340 |
| LLPS-Orl-3216 | Oryzias latipes | 47.22 | 3e-107 | 336 |
| LLPS-Mod-2641 | Monodelphis domestica | 47.02 | 1e-107 | 337 |
| LLPS-Ten-1059 | Tetraodon nigroviridis | 46.91 | 3e-108 | 337 |
| LLPS-Pes-2476 | Pelodiscus sinensis | 46.52 | 7e-108 | 337 |
| LLPS-Xim-2317 | Xiphophorus maculatus | 46.34 | 4e-103 | 326 |
| LLPS-Pof-0540 | Poecilia formosa | 46.34 | 1e-102 | 325 |
| LLPS-Orn-1443 | Oreochromis niloticus | 46.14 | 3e-102 | 324 |
| LLPS-Man-3379 | Macaca nemestrina | 46.02 | 2e-99 | 315 |
| LLPS-Cap-3580 | Cavia porcellus | 45.41 | 3e-104 | 328 |
| LLPS-Fia-3804 | Ficedula albicollis | 44.31 | 3e-100 | 320 |
| LLPS-Tag-3041 | Taeniopygia guttata | 44.02 | 5e-70 | 230 |
| LLPS-Cea-4453 | Cercocebus atys | 43.83 | 2e-103 | 327 |
| LLPS-Gaga-3983 | Gallus gallus | 43.72 | 8e-96 | 306 |
| LLPS-Lac-1698 | Latimeria chalumnae | 43.3 | 5e-42 | 161 |
| LLPS-Dio-3991 | Dipodomys ordii | 41.53 | 8e-84 | 275 |
| LLPS-Dos-0649 | Dothistroma septosporum | 41.53 | 1e-52 | 194 |
| LLPS-Drm-2015 | Drosophila melanogaster | 40.44 | 1e-86 | 285 |
| LLPS-Zyt-0899 | Zymoseptoria tritici | 40.0 | 2e-50 | 184 |
| LLPS-Mua-0427 | Musa acuminata | 39.92 | 3e-45 | 170 |
| LLPS-Mao-1306 | Magnaporthe oryzae | 39.34 | 2e-41 | 160 |
| LLPS-Ast-0729 | Aspergillus terreus | 39.29 | 1e-47 | 179 |
| LLPS-Asf-0446 | Aspergillus flavus | 38.87 | 1e-45 | 173 |
| LLPS-Aso-0942 | Aspergillus oryzae | 38.87 | 1e-45 | 173 |
| LLPS-Gag-1383 | Gaeumannomyces graminis | 38.4 | 2e-42 | 163 |
| LLPS-Phn-0352 | Phaeosphaeria nodorum | 38.31 | 9e-46 | 173 |
| LLPS-Fuv-0768 | Fusarium verticillioides | 38.21 | 4e-45 | 171 |
| LLPS-Map-0435 | Magnaporthe poae | 38.15 | 3e-43 | 166 |
| LLPS-Pyt-0707 | Pyrenophora teres | 37.7 | 3e-45 | 171 |
| LLPS-Asni-1464 | Aspergillus niger | 37.6 | 6e-43 | 164 |
| LLPS-Pug-0467 | Puccinia graminis | 37.44 | 2e-29 | 123 |
| LLPS-Scj-0317 | Schizosaccharomyces japonicus | 37.35 | 1e-37 | 150 |
| LLPS-Pytr-1407 | Pyrenophora triticirepentis | 37.3 | 8e-45 | 170 |
| LLPS-Scc-0964 | Schizosaccharomyces cryophilus | 37.27 | 1e-49 | 183 |
| LLPS-Scp-1081 | Schizosaccharomyces pombe | 37.16 | 2e-38 | 152 |
| LLPS-Fuo-0985 | Fusarium oxysporum | 37.1 | 4e-45 | 171 |
| LLPS-Scs-0975 | Sclerotinia sclerotiorum | 36.8 | 1e-47 | 178 |
| LLPS-Vir-2225 | Vigna radiata | 36.74 | 7e-32 | 131 |
| LLPS-Asc-1617 | Aspergillus clavatus | 36.51 | 3e-43 | 166 |
| LLPS-Beb-0111 | Beauveria bassiana | 36.48 | 8e-46 | 173 |
| LLPS-Php-1466 | Physcomitrella patens | 36.47 | 2e-31 | 132 |
| LLPS-Asfu-1115 | Aspergillus fumigatus | 36.44 | 1e-41 | 160 |
| LLPS-Ved-0436 | Verticillium dahliae | 36.36 | 5e-44 | 168 |
| LLPS-Cogr-1317 | Colletotrichum graminicola | 36.22 | 7e-46 | 173 |
| LLPS-Fus-1148 | Fusarium solani | 36.18 | 9e-46 | 172 |
| LLPS-Coo-1587 | Colletotrichum orbiculare | 36.14 | 9e-44 | 167 |
| LLPS-Nef-1638 | Neosartorya fischeri | 36.03 | 4e-41 | 159 |
| LLPS-Kop-1493 | Komagataella pastoris | 35.8 | 9e-37 | 145 |
| LLPS-Asn-0737 | Aspergillus nidulans | 35.71 | 2e-35 | 142 |
| LLPS-Nec-1085 | Neurospora crassa | 35.25 | 9e-42 | 162 |
| LLPS-Cae-0632 | Caenorhabditis elegans | 35.09 | 3e-33 | 135 |
| LLPS-Meg-1628 | Meleagris gallopavo | 35.06 | 2e-35 | 144 |
| LLPS-Tut-2011 | Tursiops truncatus | 35.04 | 8e-30 | 127 |
| LLPS-Put-0683 | Puccinia triticina | 34.91 | 4e-32 | 131 |
| LLPS-Mel-0872 | Melampsora laricipopulina | 34.87 | 3e-30 | 122 |
| LLPS-Sem-1275 | Selaginella moellendorffii | 34.79 | 8e-55 | 194 |
| LLPS-Phv-0929 | Phaseolus vulgaris | 34.57 | 3e-29 | 125 |
| LLPS-Cym-0120 | Cyanidioschyzon merolae | 34.36 | 3e-31 | 131 |
| LLPS-Abg-1068 | Absidia glauca | 34.32 | 2e-36 | 145 |
| LLPS-Trr-0200 | Trichoderma reesei | 34.22 | 7e-36 | 145 |
| LLPS-Via-2364 | Vigna angularis | 34.2 | 1e-29 | 126 |
| LLPS-Blg-0779 | Blumeria graminis | 34.15 | 3e-39 | 154 |
| LLPS-Art-2425 | Arabidopsis thaliana | 34.14 | 4e-33 | 137 |
| LLPS-Amt-1811 | Amborella trichopoda | 34.05 | 2e-57 | 204 |
| LLPS-Hea-0384 | Helianthus annuus | 33.73 | 8e-56 | 200 |
| LLPS-Viv-2080 | Vitis vinifera | 33.66 | 2e-54 | 196 |
| LLPS-Sei-2470 | Setaria italica | 33.57 | 2e-59 | 208 |
| LLPS-Gor-2312 | Gossypium raimondii | 33.57 | 6e-59 | 207 |
| LLPS-Trv-0956 | Trichoderma virens | 33.46 | 6e-36 | 145 |
| LLPS-Lem-1200 | Leptosphaeria maculans | 33.33 | 8e-34 | 139 |
| LLPS-Coc-1854 | Corchorus capsularis | 33.33 | 3e-49 | 181 |
| LLPS-Prp-1337 | Prunus persica | 33.33 | 1e-50 | 186 |
| LLPS-Gas-1190 | Galdieria sulphuraria | 33.2 | 1e-31 | 131 |
| LLPS-Lep-2308 | Leersia perrieri | 33.17 | 2e-56 | 202 |
| LLPS-Glm-1164 | Glycine max | 33.09 | 4e-30 | 128 |
| LLPS-Cus-2404 | Cucumis sativus | 33.01 | 3e-50 | 184 |
| LLPS-Ori-0701 | Oryza indica | 32.94 | 2e-54 | 196 |
| LLPS-Zem-2578 | Zea mays | 32.93 | 9e-57 | 201 |
| LLPS-Orni-0379 | Oryza nivara | 32.85 | 2e-54 | 196 |
| LLPS-Orr-0250 | Oryza rufipogon | 32.85 | 4e-53 | 194 |
| LLPS-Orm-1579 | Oryza meridionalis | 32.85 | 1e-53 | 193 |
| LLPS-Tru-0765 | Triticum urartu | 32.81 | 2e-28 | 122 |
| LLPS-Orgl-1904 | Oryza glumaepatula | 32.78 | 1e-52 | 194 |
| LLPS-Brd-0573 | Brachypodium distachyon | 32.77 | 5e-55 | 198 |
| LLPS-Tra-0490 | Triticum aestivum | 32.61 | 6e-57 | 201 |
| LLPS-Orb-2025 | Oryza barthii | 32.61 | 9e-53 | 193 |
| LLPS-Thc-2182 | Theobroma cacao | 32.55 | 1e-53 | 194 |
| LLPS-Ors-1285 | Oryza sativa | 32.54 | 1e-55 | 199 |
| LLPS-Hov-1191 | Hordeum vulgare | 32.51 | 4e-54 | 193 |
| LLPS-Orbr-2208 | Oryza brachyantha | 32.46 | 8e-54 | 193 |
| LLPS-Chc-0589 | Chondrus crispus | 32.35 | 8e-30 | 125 |
| LLPS-Sot-2207 | Solanum tuberosum | 32.33 | 2e-54 | 196 |
| LLPS-Mae-2152 | Manihot esculenta | 32.32 | 2e-55 | 199 |
| LLPS-Org-2243 | Oryza glaberrima | 32.3 | 2e-55 | 198 |
| LLPS-Sob-0079 | Sorghum bicolor | 32.29 | 8e-58 | 204 |
| LLPS-Yal-1327 | Yarrowia lipolytica | 32.28 | 1e-32 | 135 |
| LLPS-Chr-1502 | Chlamydomonas reinhardtii | 32.19 | 3e-35 | 144 |
| LLPS-Pot-2291 | Populus trichocarpa | 32.07 | 8e-56 | 199 |
| LLPS-Cog-0822 | Colletotrichum gloeosporioides | 31.87 | 1e-47 | 178 |
| LLPS-Bro-1542 | Brassica oleracea | 31.85 | 9e-55 | 197 |
| LLPS-Osl-1160 | Ostreococcus lucimarinus | 31.6 | 6e-51 | 184 |
| LLPS-Sol-2414 | Solanum lycopersicum | 31.4 | 5e-53 | 192 |
| LLPS-Arl-2788 | Arabidopsis lyrata | 31.39 | 3e-53 | 192 |
| LLPS-Brr-2233 | Brassica rapa | 31.36 | 2e-54 | 195 |
| LLPS-Orp-2401 | Oryza punctata | 31.34 | 3e-51 | 186 |
| LLPS-Brn-3369 | Brassica napus | 31.11 | 3e-53 | 191 |
| LLPS-Nia-1534 | Nicotiana attenuata | 30.99 | 1e-49 | 182 |
| LLPS-Met-1907 | Medicago truncatula | 30.57 | 4e-49 | 181 |
| LLPS-Dac-2329 | Daucus carota | 30.43 | 2e-53 | 192 |
| LLPS-Usm-1255 | Ustilago maydis | 30.18 | 4e-31 | 131 |
| LLPS-Spr-1225 | Sporisorium reilianum | 29.14 | 1e-28 | 124 |
| LLPS-Asg-1001 | Ashbya gossypii | 25.36 | 4e-33 | 135 |