• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Caj-1645

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: Small nuclear ribonucleoprotein G
Ensembl Gene: ENSCJAG00000040628.1
Ensembl Protein: ENSCJAP00000067488.1
Organism: Callithrix jacchus
Taxa ID: 9483
LLPS Type: Client


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
Nuclear speckle, NucleolusPredicted from orthologs(View)

▼ FUNCTION


Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.

▼ CROSS REFERENCE


DatabaseNucleotide IDProtein ID
EnsemblENSCJAT00000044253.3ENSCJAP00000067488.1
UniProtA0A2R8N006, A0A2R8N006_CALJA

▼ SEQUENCE


Protein Sequence (FASTA)
1     MSKAHPPELK  KFMDKKLSLK  LNGGRYVQGI  LRGFDPFMNL  VMDECVEMAT  SGQQNNIGMV  60
61    VIRGNSIIML  EALERV  76
Nucleotide CDS Sequence (FASTA)
1     ATGAGCAAAG  CTCACCCTCC  CGAGTTGAAA  AAATTTATGG  ACAAGAAGTT  ATCATTGAAA  60
61    TTAAATGGTG  GCAGATACGT  CCAAGGAATA  TTGCGGGGAT  TTGATCCCTT  TATGAATCTT  120
121   GTGATGGATG  AATGTGTGGA  GATGGCGACT  AGTGGACAAC  AGAATAATAT  TGGAATGGTG  180
181   GTAATACGCG  GAAATAGTAT  CATCATGTTA  GAAGCCTTGG  AACGAGTATA  A  231

▼ KEYWORD


ID
Family
Complete proteome
Cytoplasm
mRNA processing
mRNA splicing
Nucleus
Reference proteome
Ribonucleoprotein
RNA-binding
Spliceosome

▼ GENE ONTOLOGY


ID
Classification
Description
Cellular Component
Cytosol
Cellular Component
Spliceosomal complex
Molecular Function
RNA binding
Biological Process
Spliceosomal snRNP assembly

▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Fec-2213Felis catus97.374e-48 153
LLPS-Loa-1168Loxodonta africana97.374e-48 153
LLPS-Rhb-0470Rhinopithecus bieti97.374e-48 153
LLPS-Cap-0541Cavia porcellus97.374e-48 153
LLPS-Poa-1730Pongo abelii97.374e-48 153
LLPS-Caf-0065Canis familiaris97.374e-48 153
LLPS-Ict-1868Ictidomys tridecemlineatus97.374e-48 153
LLPS-Chs-2425Chlorocebus sabaeus97.374e-48 153
LLPS-Mum-0702Mus musculus97.374e-48 153
LLPS-Mea-2587Mesocricetus auratus97.374e-48 153
LLPS-Sus-3174Sus scrofa97.374e-48 153
LLPS-Fud-2550Fukomys damarensis97.374e-48 153
LLPS-Bot-3737Bos taurus97.371e-47 152
LLPS-Dio-1221Dipodomys ordii97.374e-48 153
LLPS-Ran-1864Rattus norvegicus97.374e-48 153
LLPS-Mup-1179Mustela putorius furo97.374e-48 153
LLPS-Ova-4370Ovis aries97.374e-48 153
LLPS-Tut-2081Tursiops truncatus96.926e-39 129
LLPS-Aim-1012Ailuropoda melanoleuca96.678e-37 125
LLPS-Orc-0726Oryctolagus cuniculus96.053e-47 151
LLPS-Mam-2005Macaca mulatta96.054e-47 150
LLPS-Maf-3151Macaca fascicularis96.051e-47 152
LLPS-Myl-1708Myotis lucifugus96.052e-47 151
LLPS-Ere-0219Erinaceus europaeus95.952e-45 146
LLPS-Cea-0058Cercocebus atys95.892e-45 146
LLPS-Mal-3916Mandrillus leucophaeus95.892e-45 146
LLPS-Cas-0699Carlito syrichta95.248e-38 127
LLPS-Mod-2014Monodelphis domestica94.743e-46 148
LLPS-Gaga-1851Gallus gallus94.743e-46 148
LLPS-Aon-0938Aotus nancymaae94.743e-46 148
LLPS-Sah-3646Sarcophilus harrisii94.743e-46 148
LLPS-Urm-2747Ursus maritimus94.121e-39 132
LLPS-Leo-2152Lepisosteus oculatus93.427e-46 147
LLPS-Paa-2903Papio anubis93.429e-45 145
LLPS-Gaa-0947Gasterosteus aculeatus93.023e-2286.3
LLPS-Man-1397Macaca nemestrina91.787e-42 137
LLPS-Lac-0761Latimeria chalumnae90.796e-44 142
LLPS-Pof-0529Poecilia formosa90.793e-44 143
LLPS-Xim-0978Xiphophorus maculatus90.793e-44 143
LLPS-Pap-0361Pan paniscus89.472e-40 134
LLPS-Scf-0591Scleropages formosus89.471e-43 142
LLPS-Nol-3941Nomascus leucogenys89.398e-36 122
LLPS-Anp-1481Anas platyrhynchos88.572e-37 125
LLPS-Fia-0269Ficedula albicollis88.577e-38 127
LLPS-Orl-0980Oryzias latipes88.334e-33 115
LLPS-Scm-0992Scophthalmus maximus88.167e-43 140
LLPS-Dar-0747Danio rerio88.161e-42 139
LLPS-Pat-1019Pan troglodytes88.166e-40 132
LLPS-Ten-2547Tetraodon nigroviridis88.162e-42 139
LLPS-Xet-1977Xenopus tropicalis88.163e-43 140
LLPS-Asm-0036Astyanax mexicanus86.895e-33 115
LLPS-Gog-3918Gorilla gorilla86.841e-38 129
LLPS-Eqc-1975Equus caballus86.762e-35 120
LLPS-Otg-0623Otolemur garnettii86.491e-39 132
LLPS-Tag-1223Taeniopygia guttata84.214e-39 130
LLPS-Icp-2284Ictalurus punctatus84.212e-37 125
LLPS-Anc-0147Anolis carolinensis82.894e-40 133
LLPS-Hos-0273Homo sapiens80.264e-37 125
LLPS-Tar-1588Takifugu rubripes72.52e-32 113
LLPS-Drm-0884Drosophila melanogaster72.376e-35 120
LLPS-Mua-2308Musa acuminata64.945e-2799.8
LLPS-Cae-0605Caenorhabditis elegans64.471e-30 108
LLPS-Amt-0535Amborella trichopoda63.649e-2696.7
LLPS-Php-0089Physcomitrella patens63.641e-2698.6
LLPS-Fuo-1053Fusarium oxysporum62.861e-2596.3
LLPS-Ors-1675Oryza sativa62.344e-2594.7
LLPS-Sob-2118Sorghum bicolor62.342e-2595.9
LLPS-Orbr-0992Oryza brachyantha62.343e-2595.1
LLPS-Orr-0533Oryza rufipogon62.344e-2594.7
LLPS-Org-2066Oryza glaberrima62.344e-2594.7
LLPS-Ori-0995Oryza indica62.344e-2594.7
LLPS-Orni-0866Oryza nivara62.344e-2594.7
LLPS-Orgl-1473Oryza glumaepatula62.344e-2594.7
LLPS-Lep-0600Leersia perrieri62.343e-2595.1
LLPS-Sei-1369Setaria italica62.343e-2595.1
LLPS-Nef-0293Neosartorya fischeri61.431e-2391.3
LLPS-Ved-1346Verticillium dahliae61.435e-2594.7
LLPS-Asc-1014Aspergillus clavatus61.431e-2391.3
LLPS-Asf-0442Aspergillus flavus61.431e-2390.9
LLPS-Brd-0483Brachypodium distachyon61.332e-2492.8
LLPS-Brr-0566Brassica rapa61.041e-2390.9
LLPS-Art-0608Arabidopsis thaliana61.046e-2491.7
LLPS-Mae-0655Manihot esculenta61.042e-2492.8
LLPS-Coc-0987Corchorus capsularis61.044e-2492.4
LLPS-Prp-0016Prunus persica61.042e-2492.8
LLPS-Bro-0493Brassica oleracea61.042e-2390.5
LLPS-Zem-1460Zea mays61.042e-2492.8
LLPS-Glm-0090Glycine max61.047e-2594.4
LLPS-Brn-1027Brassica napus61.042e-2390.5
LLPS-Arl-1803Arabidopsis lyrata61.042e-2390.5
LLPS-Chr-0419Chlamydomonas reinhardtii60.533e-2389.7
LLPS-Ast-1460Aspergillus terreus60.02e-2390.5
LLPS-Trr-1345Trichoderma reesei60.02e-2493.2
LLPS-Trv-0766Trichoderma virens60.02e-2493.2
LLPS-Asfu-1175Aspergillus fumigatus60.02e-2390.5
LLPS-Cogr-0050Colletotrichum graminicola60.01e-2493.6
LLPS-Scs-0548Sclerotinia sclerotiorum60.02e-2492.8
LLPS-Coo-1229Colletotrichum orbiculare60.01e-2493.6
LLPS-Blg-1289Blumeria graminis60.04e-2492.4
LLPS-Gor-0552Gossypium raimondii59.742e-2390.5
LLPS-Viv-0029Vitis vinifera59.741e-2390.9
LLPS-Sem-1971Selaginella moellendorffii59.748e-2389.0
LLPS-Sol-1586Solanum lycopersicum59.741e-2390.9
LLPS-Hea-1793Helianthus annuus59.741e-2391.3
LLPS-Dac-1405Daucus carota59.747e-2491.7
LLPS-Thc-0041Theobroma cacao59.742e-2390.5
LLPS-Sot-0108Solanum tuberosum59.746e-2492.0
LLPS-Cus-0858Cucumis sativus59.741e-2390.9
LLPS-Asn-0186Aspergillus nidulans58.575e-2389.4
LLPS-Tum-0931Tuber melanosporum58.576e-2491.7
LLPS-Pot-1905Populus trichocarpa58.443e-2390.1
LLPS-Orp-0729Oryza punctata58.448e-2491.7
LLPS-Phv-0758Phaseolus vulgaris58.442e-2390.5
LLPS-Orm-1156Oryza meridionalis58.447e-2492.0
LLPS-Orb-1806Oryza barthii58.448e-2491.7
LLPS-Met-0712Medicago truncatula58.441e-2391.3
LLPS-Vir-0696Vigna radiata58.448e-2390.5
LLPS-Aso-0990Aspergillus oryzae57.631e-1571.2
LLPS-Cog-0643Colletotrichum gloeosporioides56.452e-1980.9
LLPS-Put-0596Puccinia triticina55.841e-2186.3
LLPS-Mel-0972Melampsora laricipopulina55.843e-2184.7
LLPS-Beb-0954Beauveria bassiana55.713e-2390.1
LLPS-Gag-0693Gaeumannomyces graminis55.716e-2389.4
LLPS-Lem-0748Leptosphaeria maculans55.714e-2389.7
LLPS-Nec-1140Neurospora crassa55.714e-2389.7
LLPS-Crn-0053Cryptococcus neoformans55.419e-2286.3
LLPS-Chc-0632Chondrus crispus54.935e-2389.4
LLPS-Sac-1057Saccharomyces cerevisiae54.792e-1877.8
LLPS-Tra-0731Triticum aestivum54.675e-1979.3
LLPS-Pug-1293Puccinia graminis54.552e-2185.5
LLPS-Phn-0789Phaeosphaeria nodorum54.293e-2390.1
LLPS-Map-0419Magnaporthe poae54.297e-2389.4
LLPS-Hov-1928Hordeum vulgare54.221e-2084.0
LLPS-Osl-1122Ostreococcus lucimarinus53.128e-1773.2
LLPS-Pytr-1112Pyrenophora triticirepentis52.863e-2287.8
LLPS-Dos-0742Dothistroma septosporum52.861e-2288.6
LLPS-Mao-0602Magnaporthe oryzae52.863e-2185.1
LLPS-Pyt-0110Pyrenophora teres52.863e-2287.8
LLPS-Asg-0102Ashbya gossypii51.436e-1978.6
LLPS-Zyt-1160Zymoseptoria tritici51.431e-2185.5
LLPS-Miv-0936Microbotryum violaceum50.79e-1670.5
LLPS-Gas-0128Galdieria sulphuraria50.76e-2184.0
LLPS-Scc-1001Schizosaccharomyces cryophilus50.04e-2389.7
LLPS-Usm-0207Ustilago maydis48.816e-2081.6
LLPS-Spr-0316Sporisorium reilianum48.815e-2082.0
LLPS-Scj-0662Schizosaccharomyces japonicus48.681e-2288.6
LLPS-Scp-0638Schizosaccharomyces pombe48.01e-2185.9
LLPS-Asni-1169Aspergillus niger47.894e-1774.7
LLPS-Kop-0447Komagataella pastoris45.715e-1876.6
LLPS-Fus-0326Fusarium solani38.032e-1263.2
LLPS-Fuv-0841Fusarium verticillioides38.032e-1262.8
LLPS-Via-0041Vigna angularis37.332e-1262.0
LLPS-Abg-1600Absidia glauca36.493e-1159.7