• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Sus-3174
SNRPG

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: Small nuclear ribonucleoprotein G
Gene Name: SNRPG
Ensembl Gene: ENSSSCG00000024776.2
Ensembl Protein: ENSSSCP00000025138.1
Organism: Sus scrofa
Taxa ID: 9823
LLPS Type: Others


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
Cajal body, Nuclear speckle, NucleolusPredicted from orthologs(View)

▼ FUNCTION


Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.

▼ CROSS REFERENCE


▼ SEQUENCE


Protein Sequence (FASTA)
1     MSKAHPPELK  KFMDKKLSLK  LNGGRHVQGI  LRGFDPFMNL  VIDECVEMAT  SGQQNNIGMV  60
61    VIRGNSIIML  EALERV  76
Nucleotide CDS Sequence (FASTA)
1     ATGAGCAAAG  CTCACCCGCC  GGAGTTGAAG  AAATTTATGG  ACAAGAAATT  ATCATTGAAA  60
61    TTAAATGGTG  GCAGACATGT  CCAAGGAATA  TTGCGAGGAT  TTGACCCCTT  TATGAACCTT  120
121   GTGATAGATG  AATGTGTGGA  GATGGCAACA  AGTGGTCAAC  AGAACAATAT  TGGAATGGTG  180
181   GTAATACGAG  GAAACAGTAT  CATCATGTTA  GAAGCCTTGG  AACGAGTATG  A  231

▼ KEYWORD


ID
Family
Complete proteome
Cytoplasm
mRNA processing
mRNA splicing
Nucleus
Proteomics identification
Reference proteome
Ribonucleoprotein
RNA-binding
Spliceosome

▼ GENE ONTOLOGY


ID
Classification
Description
Cellular Component
Catalytic step 2 spliceosome
Cellular Component
Cytosol
Cellular Component
P granule
Cellular Component
SMN-Sm protein complex
Cellular Component
U1 snRNP
Cellular Component
U12-type spliceosomal complex
Cellular Component
U2 snRNP
Cellular Component
U2-type prespliceosome
Cellular Component
U4 snRNP
Cellular Component
U5 snRNP
Molecular Function
RNA binding
Biological Process
Spliceosomal snRNP assembly

▼ KEGG



▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Tut-2081Tursiops truncatus100.04e-40 132
LLPS-Bot-1941Bos taurus100.03e-49 156
LLPS-Dio-1221Dipodomys ordii100.03e-49 156
LLPS-Ran-1864Rattus norvegicus100.03e-49 156
LLPS-Aim-1012Ailuropoda melanoleuca100.06e-38 128
LLPS-Mup-1179Mustela putorius furo100.03e-49 156
LLPS-Ova-4370Ovis aries100.03e-49 156
LLPS-Chs-2425Chlorocebus sabaeus100.03e-49 156
LLPS-Mum-0702Mus musculus100.03e-49 156
LLPS-Mea-2587Mesocricetus auratus100.03e-49 156
LLPS-Fud-2550Fukomys damarensis100.03e-49 156
LLPS-Cap-0541Cavia porcellus100.03e-49 156
LLPS-Poa-1730Pongo abelii100.03e-49 156
LLPS-Caf-0065Canis familiaris100.03e-49 156
LLPS-Ict-1868Ictidomys tridecemlineatus100.03e-49 156
LLPS-Fec-2213Felis catus100.03e-49 156
LLPS-Loa-1168Loxodonta africana100.03e-49 156
LLPS-Rhb-0470Rhinopithecus bieti100.03e-49 156
LLPS-Caj-3021Callithrix jacchus98.72e-47 151
LLPS-Myl-1708Myotis lucifugus98.682e-48 154
LLPS-Maf-3151Macaca fascicularis98.689e-49 155
LLPS-Mam-2005Macaca mulatta98.683e-48 154
LLPS-Orc-0726Oryctolagus cuniculus98.683e-48 154
LLPS-Ere-0219Erinaceus europaeus98.651e-46 149
LLPS-Mal-3916Mandrillus leucophaeus98.631e-46 149
LLPS-Cea-0058Cercocebus atys98.631e-46 149
LLPS-Cas-0699Carlito syrichta98.414e-39 130
LLPS-Aon-0938Aotus nancymaae97.372e-47 151
LLPS-Sah-3646Sarcophilus harrisii97.372e-47 151
LLPS-Gaga-1851Gallus gallus97.372e-47 151
LLPS-Mod-2014Monodelphis domestica97.372e-47 151
LLPS-Urm-2747Ursus maritimus97.065e-41 135
LLPS-Paa-2903Papio anubis96.054e-46 148
LLPS-Gaa-0947Gasterosteus aculeatus95.353e-2389.0
LLPS-Leo-2152Lepisosteus oculatus93.427e-46 147
LLPS-Lac-0761Latimeria chalumnae93.426e-45 145
LLPS-Man-1397Macaca nemestrina93.151e-42 139
LLPS-Nol-3941Nomascus leucogenys92.424e-37 125
LLPS-Pap-0361Pan paniscus92.111e-41 136
LLPS-Anp-1481Anas platyrhynchos91.432e-38 129
LLPS-Fia-0269Ficedula albicollis91.433e-39 130
LLPS-Xim-0978Xiphophorus maculatus90.792e-44 144
LLPS-Xet-1977Xenopus tropicalis90.793e-44 143
LLPS-Pof-0529Poecilia formosa90.792e-44 144
LLPS-Pat-1019Pan troglodytes90.794e-41 135
LLPS-Eqc-1975Equus caballus89.712e-36 123
LLPS-Scf-0591Scleropages formosus89.471e-43 142
LLPS-Gog-3918Gorilla gorilla89.479e-40 132
LLPS-Ten-2547Tetraodon nigroviridis89.472e-43 141
LLPS-Scm-0992Scophthalmus maximus89.472e-43 141
LLPS-Dar-0747Danio rerio89.471e-43 142
LLPS-Otg-0623Otolemur garnettii89.198e-41 134
LLPS-Asm-0036Astyanax mexicanus88.526e-34 117
LLPS-Orl-0980Oryzias latipes88.335e-33 115
LLPS-Tag-1223Taeniopygia guttata86.843e-40 133
LLPS-Icp-2284Ictalurus punctatus85.533e-38 128
LLPS-Anc-0147Anolis carolinensis85.532e-41 136
LLPS-Hos-0273Homo sapiens82.892e-38 129
LLPS-Tar-1588Takifugu rubripes73.751e-33 116
LLPS-Drm-0884Drosophila melanogaster72.376e-35 120
LLPS-Cae-0605Caenorhabditis elegans65.792e-31 110
LLPS-Mua-2308Musa acuminata64.944e-27 100
LLPS-Amt-0535Amborella trichopoda64.947e-2697.1
LLPS-Php-0089Physcomitrella patens63.644e-2799.8
LLPS-Sob-2118Sorghum bicolor63.641e-2596.3
LLPS-Fuo-1053Fusarium oxysporum62.867e-2697.1
LLPS-Orgl-1473Oryza glumaepatula62.343e-2595.1
LLPS-Lep-0600Leersia perrieri62.342e-2595.5
LLPS-Sei-1369Setaria italica62.343e-2595.1
LLPS-Ori-0995Oryza indica62.343e-2595.1
LLPS-Orni-0866Oryza nivara62.343e-2595.1
LLPS-Orr-0533Oryza rufipogon62.343e-2595.1
LLPS-Org-2066Oryza glaberrima62.343e-2595.1
LLPS-Zem-1460Zea mays62.341e-2493.6
LLPS-Ors-1675Oryza sativa62.343e-2595.1
LLPS-Orbr-0992Oryza brachyantha62.342e-2595.5
LLPS-Chr-0419Chlamydomonas reinhardtii61.846e-2491.7
LLPS-Asf-0442Aspergillus flavus61.435e-2492.0
LLPS-Asc-1014Aspergillus clavatus61.434e-2492.0
LLPS-Ved-1346Verticillium dahliae61.433e-2595.5
LLPS-Nef-0293Neosartorya fischeri61.434e-2492.0
LLPS-Brd-0483Brachypodium distachyon61.332e-2493.2
LLPS-Sot-0108Solanum tuberosum61.043e-2492.4
LLPS-Arl-0301Arabidopsis lyrata61.043e-2492.8
LLPS-Glm-1784Glycine max61.047e-2594.4
LLPS-Sol-0172Solanum lycopersicum61.044e-2492.4
LLPS-Brn-1027Brassica napus61.048e-2491.3
LLPS-Hea-1793Helianthus annuus61.043e-2492.4
LLPS-Dac-1405Daucus carota61.042e-2493.2
LLPS-Coc-0987Corchorus capsularis61.041e-2493.6
LLPS-Prp-0016Prunus persica61.041e-2493.6
LLPS-Bro-0493Brassica oleracea61.048e-2491.3
LLPS-Brr-0566Brassica rapa61.045e-2492.0
LLPS-Art-1770Arabidopsis thaliana61.048e-2491.3
LLPS-Mae-0655Manihot esculenta61.049e-2594.0
LLPS-Blg-1581Blumeria graminis60.02e-2492.8
LLPS-Scs-0548Sclerotinia sclerotiorum60.01e-2493.6
LLPS-Coo-1229Colletotrichum orbiculare60.09e-2594.0
LLPS-Trv-0766Trichoderma virens60.01e-2494.0
LLPS-Asfu-1175Aspergillus fumigatus60.07e-2491.7
LLPS-Cogr-0050Colletotrichum graminicola60.09e-2594.0
LLPS-Ast-1460Aspergillus terreus60.08e-2491.3
LLPS-Trr-1345Trichoderma reesei60.01e-2494.0
LLPS-Cus-0858Cucumis sativus59.741e-2391.3
LLPS-Sem-1971Selaginella moellendorffii59.741e-2288.6
LLPS-Thc-0041Theobroma cacao59.747e-2491.7
LLPS-Gor-0552Gossypium raimondii59.746e-2491.7
LLPS-Viv-0029Vitis vinifera59.745e-2492.0
LLPS-Tum-0931Tuber melanosporum58.574e-2492.4
LLPS-Asn-0186Aspergillus nidulans58.572e-2390.5
LLPS-Met-0712Medicago truncatula58.445e-2492.0
LLPS-Vir-0696Vigna radiata58.443e-2391.3
LLPS-Orb-1806Oryza barthii58.446e-2492.0
LLPS-Orm-1156Oryza meridionalis58.446e-2492.0
LLPS-Pot-2315Populus trichocarpa58.442e-2390.9
LLPS-Orp-0729Oryza punctata58.446e-2492.0
LLPS-Phv-0758Phaseolus vulgaris58.449e-2491.3
LLPS-Aso-0990Aspergillus oryzae57.638e-1672.0
LLPS-Cog-0643Colletotrichum gloeosporioides56.451e-1981.3
LLPS-Mel-0972Melampsora laricipopulina55.842e-2185.5
LLPS-Put-0596Puccinia triticina55.845e-2286.7
LLPS-Lem-0748Leptosphaeria maculans55.712e-2390.5
LLPS-Nec-1140Neurospora crassa55.712e-2390.5
LLPS-Gag-0693Gaeumannomyces graminis55.713e-2390.5
LLPS-Beb-0954Beauveria bassiana55.712e-2390.9
LLPS-Crn-0053Cryptococcus neoformans55.412e-2288.2
LLPS-Chc-0632Chondrus crispus54.933e-2389.7
LLPS-Sac-1057Saccharomyces cerevisiae54.791e-1878.2
LLPS-Tra-0731Triticum aestivum54.675e-1979.0
LLPS-Pug-1293Puccinia graminis54.558e-2286.3
LLPS-Map-0419Magnaporthe poae54.293e-2390.1
LLPS-Phn-0789Phaeosphaeria nodorum54.291e-2390.9
LLPS-Hov-1928Hordeum vulgare54.226e-2184.3
LLPS-Osl-1122Ostreococcus lucimarinus53.125e-1773.6
LLPS-Pyt-0110Pyrenophora teres52.861e-2288.6
LLPS-Mao-0602Magnaporthe oryzae52.861e-2185.9
LLPS-Pytr-1112Pyrenophora triticirepentis52.861e-2288.6
LLPS-Dos-0742Dothistroma septosporum52.868e-2389.0
LLPS-Zyt-1160Zymoseptoria tritici51.437e-2286.7
LLPS-Asg-0102Ashbya gossypii51.436e-1979.0
LLPS-Gas-0128Galdieria sulphuraria50.73e-2184.7
LLPS-Miv-0936Microbotryum violaceum50.74e-1671.6
LLPS-Scc-1001Schizosaccharomyces cryophilus50.02e-2390.5
LLPS-Usm-0207Ustilago maydis48.813e-2082.4
LLPS-Spr-0316Sporisorium reilianum48.812e-2082.8
LLPS-Scj-0662Schizosaccharomyces japonicus48.682e-2390.9
LLPS-Scp-0638Schizosaccharomyces pombe48.05e-2287.0
LLPS-Asni-1169Aspergillus niger47.892e-1775.5
LLPS-Kop-0447Komagataella pastoris45.714e-1876.6
LLPS-Fuv-0841Fusarium verticillioides38.031e-1263.2
LLPS-Fus-0326Fusarium solani38.031e-1263.5
LLPS-Via-0041Vigna angularis37.331e-1262.8
LLPS-Abg-1600Absidia glauca36.491e-1160.8