LLPS-Caf-3254
IGF1R
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Tyrosine-protein kinase receptor |
| Gene Name: | IGF1R |
| Ensembl Gene: | ENSCAFG00000010881.3 |
| Ensembl Protein: | ENSCAFP00000016006.3 |
| Organism: | Canis familiaris |
| Taxa ID: | 9615 |
| LLPS Type: | Regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule, Others | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSCAFT00000017295.3 | ENSCAFP00000016006.3 |
| UniProt | F1PXU6, F1PXU6_CANLF | |
| GeneBank | AAEX03002258, AAEX03002259, AAEX03002257, AAEX03002256 | |
| RefSeq | XM_545828.5 | XP_545828.2 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MKSGSGGGSP TSLWGLVFLS AALSLWPTSG EICGPGIDIR NDYQQLKRLE NCTVIEGYLH 60 61 ILLISKAEDY RSYRFPKLTV ITEYLLLFRV AGLESLGDLF PNLTVIRGWK LFYNYALVIF 120 121 EMTNLKDIGL YNLRNITRGA IRIEKNADLC YLSTVDWSLI LDAVSNNYIV GNKPPKECGD 180 181 LCPGTMEEKP LCEKTTINNE YNYRCWTTNR CQKMCPSACG KRACTENNEC CHPECLGSCS 240 241 APDNDTACVA CRHYYYAGVC VPTCPPNTYR FEGWRCVDRD FCANIPSAES SDSEGFVIHD 300 301 GECMQECPSG FIRNGSQSMY CIPCEGPCPK VCEEEKKTKT IDSVTSAQML QGCTIFKGNL 360 361 LINIRRGNNI ASELENFMGL IEVVTGYVKI RHSHALVSLS FLKNLRQILG EEQLEGNYSF 420 421 YVLDNQNLQQ LWDWDHRNLT IKAGKMYFAF NPKLCVSEIY RMEEVTGTKG RQSKGDINTR 480 481 NNGERASCES DVLHFTSTTT WKNRIIITWH RYRPPDYRDL ISFTVYYKEA PFKNVTEYDG 540 541 QDACGSNSWN MVDVDLPPNK DVEPGILLHG LKPWTQYAVY VKAVTLTMVE NDHIRGAKSE 600 601 ILYIRTNASV PSIPLDVLSA SNSSSQLIVK WNPPSLPNGN LSYYIVRWQR QPQDSYLYRH 660 661 NYCSKDKIPI RKYADGTIDV EEVTENPKTE VCGGEKGPCC ACPKTEAEKQ AEKEEAEYRK 720 721 VFENFLHNSI FVPRPERKRR DVTQVTNTTM SSRSRNTTVV DTYNITDPEE LETEYPFFES 780 781 RVDNKERTVI SNLRPFTLYR IDIHSCNHEA EKLGCSASNF VFARTMPAEG ADDIPGPVTW 840 841 ESRPENSIFL KWPEPENPNG LILMYEIKYG SQIEDQRECV SRQEYRKYGG AKLNRLNPGN 900 901 YTARIQATSL SGNGSWTDPV FFYVPAKITY ENFIHLIIAL PVAVLLIVGG LVIMLYVFHR 960 961 RRNNSRLGNG VLYASVNPEY FSAADVYVPD EWEVAREKIT MSRELGQGSF GMVYEGVAKG 1020 1021 VVKDEPETRV AIKTVNEAAS MRERIEFLNE ASVMKEFNCH HVVRLLGVVS QGQPTLVIME 1080 1081 LMTRGDLKSY LRSLRPEIEN NPVLAPPSLS KMIQMAGEIA DGMAYLNANK FVHRDLAARN 1140 1141 CMVAEDFTVK IGDFGMTRDI YETDYYRKGG KGLLPVRWMS PESLKDGVFT THSDVWSFGV 1200 1201 VLWEIATLAE QPYQGLSNEQ VLRFVMEGGL LDKPDNCPDM LFELMRMCWQ YNPKMRPSFL 1260 1261 EIISSIKDEM EPGFREVSFY YSEENKPPEP EELDLEPENM ESVPLDPSAS SSSLPLPDRL 1320 1321 SGHKAENGPG PGVLVLRASF DERQPYAHMN GGRKNERALP LPQSSTC 1367 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGAAGTCTG GCTCCGGAGG AGGGTCCCCG ACCTCGCTGT GGGGGCTCGT GTTTCTCTCC 60 61 GCCGCGCTGT CGCTCTGGCC GACGAGTGGA GAAATCTGTG GGCCAGGCAT CGACATCCGC 120 121 AATGACTATC AGCAGCTGAA GCGCCTGGAG AACTGTACAG TGATCGAGGG CTACCTCCAC 180 181 ATCCTACTCA TCTCCAAGGC AGAGGACTAC CGCAGCTACC GCTTCCCCAA GCTCACGGTC 240 241 ATCACCGAGT ACCTGCTGCT GTTCCGTGTG GCCGGCCTTG AGAGCCTCGG GGATCTCTTC 300 301 CCCAACCTCA CAGTCATCCG CGGCTGGAAG CTCTTCTACA ACTACGCCCT GGTCATCTTT 360 361 GAGATGACCA ACCTCAAGGA TATTGGGCTT TACAATCTGA GGAACATTAC TCGGGGGGCC 420 421 ATCAGGATTG AGAAGAATGC TGACCTCTGT TACCTCTCCA CAGTGGACTG GTCCCTGATC 480 481 CTGGATGCAG TGTCCAACAA CTACATCGTG GGGAACAAAC CCCCTAAGGA ATGTGGGGAC 540 541 CTGTGTCCAG GGACAATGGA GGAGAAGCCC TTGTGTGAGA AGACTACCAT CAACAATGAA 600 601 TACAACTATC GCTGCTGGAC TACAAATCGC TGCCAGAAAA TGTGCCCGAG CGCTTGCGGG 660 661 AAGCGGGCGT GCACGGAGAA CAACGAGTGT TGTCACCCCG AGTGTCTGGG CAGCTGCAGC 720 721 GCGCCGGACA ACGATACGGC CTGTGTGGCC TGCAGGCATT ACTACTACGC AGGCGTCTGC 780 781 GTGCCCACCT GCCCGCCCAA CACCTACCGC TTTGAGGGCT GGCGCTGCGT GGACCGCGAC 840 841 TTCTGCGCCA ACATCCCCAG CGCCGAGAGC AGCGACTCCG AGGGGTTCGT GATCCATGAC 900 901 GGCGAGTGCA TGCAGGAGTG CCCCTCTGGG TTCATCCGCA ATGGCAGTCA GAGCATGTAC 960 961 TGCATCCCTT GTGAAGGTCC TTGTCCCAAG GTCTGTGAGG AAGAAAAGAA AACAAAGACC 1020 1021 ATTGATTCTG TTACCTCTGC TCAAATGCTC CAAGGATGTA CCATCTTCAA GGGCAATTTG 1080 1081 CTCATTAATA TCCGCCGAGG CAATAACATT GCCTCAGAGC TGGAGAACTT CATGGGGCTC 1140 1141 ATCGAGGTGG TGACAGGCTA CGTGAAGATC CGCCATTCCC ATGCCTTGGT CTCCCTGTCC 1200 1201 TTCCTAAAAA ACCTTCGCCA GATCTTAGGA GAGGAACAGC TGGAGGGGAA CTACTCCTTC 1260 1261 TACGTCCTCG ACAACCAGAA CTTGCAGCAG CTTTGGGATT GGGACCACCG TAACCTGACC 1320 1321 ATCAAAGCTG GGAAAATGTA TTTTGCTTTC AATCCCAAAT TGTGCGTCTC CGAAATTTAC 1380 1381 CGCATGGAAG AAGTGACGGG GACCAAAGGA CGCCAGAGCA AAGGAGACAT AAATACCAGA 1440 1441 AACAATGGAG AGCGAGCCTC CTGTGAAAGC GACGTCCTGC ACTTCACCTC TACGACCACA 1500 1501 TGGAAGAATC GCATCATCAT CACGTGGCAC CGTTACCGGC CCCCTGACTA CAGGGACCTC 1560 1561 ATCAGCTTTA CTGTCTACTA CAAGGAAGCA CCTTTTAAAA ACGTTACGGA GTATGATGGG 1620 1621 CAGGATGCCT GTGGCTCCAA CAGCTGGAAT ATGGTAGATG TGGACCTCCC TCCCAACAAG 1680 1681 GACGTTGAGC CTGGCATTTT ACTGCACGGA CTGAAGCCCT GGACGCAGTA TGCGGTTTAT 1740 1741 GTCAAGGCGG TGACCCTCAC CATGGTGGAG AATGACCACA TCCGTGGGGC TAAGAGTGAA 1800 1801 ATCTTGTACA TTCGCACCAA TGCTTCAGTT CCTTCCATTC CCCTGGATGT TCTTTCTGCA 1860 1861 TCAAACTCCT CTTCTCAGCT CATTGTGAAG TGGAACCCAC CCTCTCTGCC CAACGGTAAC 1920 1921 CTCAGTTACT ACATCGTGAG GTGGCAGCGG CAGCCCCAGG ACAGTTACCT TTACCGCCAC 1980 1981 AACTACTGCT CCAAAGATAA AATCCCCATC AGGAAGTATG CTGATGGCAC TATCGATGTC 2040 2041 GAAGAGGTGA CAGAGAATCC CAAGACCGAA GTATGTGGTG GAGAGAAGGG GCCTTGCTGT 2100 2101 GCCTGCCCCA AAACTGAGGC CGAGAAGCAG GCTGAGAAGG AGGAGGCCGA GTACCGCAAA 2160 2161 GTGTTCGAGA ATTTCCTGCA CAACTCCATC TTCGTGCCCA GACCTGAAAG GAAGCGTAGA 2220 2221 GATGTTACAC AAGTCACCAA CACCACCATG TCCAGCCGAA GCAGGAACAC CACGGTGGTG 2280 2281 GACACCTATA ATATCACAGA CCCAGAAGAG CTCGAGACAG AATACCCTTT CTTTGAGAGC 2340 2341 AGAGTGGATA ACAAGGAGAG AACTGTAATC TCTAACCTCC GGCCTTTTAC CCTGTACCGC 2400 2401 ATTGACATCC ACAGCTGTAA TCATGAGGCT GAGAAGCTGG GCTGCAGTGC CTCCAACTTT 2460 2461 GTTTTTGCAA GAACCATGCC TGCAGAAGGA GCAGATGACA TTCCTGGGCC AGTGACCTGG 2520 2521 GAGTCAAGGC CTGAAAACTC CATCTTTTTA AAGTGGCCAG AACCTGAGAA TCCCAATGGA 2580 2581 TTGATTCTAA TGTATGAAAT AAAATATGGA TCCCAAATCG AGGATCAGCG GGAATGTGTA 2640 2641 TCCAGACAGG AGTACAGGAA GTATGGAGGT GCCAAGCTTA ACCGGCTCAA CCCGGGGAAC 2700 2701 TATACAGCCC GGATCCAGGC CACTTCTCTC TCTGGGAATG GGTCGTGGAC GGATCCTGTG 2760 2761 TTCTTCTATG TCCCAGCCAA AATAACGTAT GAAAACTTCA TCCATCTGAT CATTGCTCTG 2820 2821 CCCGTTGCTG TGCTATTGAT AGTGGGAGGG TTGGTTATAA TGCTGTACGT CTTCCACAGG 2880 2881 AGAAGAAATA ACAGCAGGCT GGGGAATGGA GTGCTGTATG CTTCCGTGAA CCCAGAATAC 2940 2941 TTCAGTGCTG CCGATGTGTA TGTACCTGAT GAGTGGGAGG TTGCTCGAGA GAAGATCACC 3000 3001 ATGAGCCGAG AGCTGGGCCA GGGCTCGTTT GGGATGGTAT ATGAAGGAGT TGCCAAGGGT 3060 3061 GTGGTTAAAG ATGAGCCTGA AACAAGGGTG GCCATTAAAA CAGTGAACGA GGCCGCCAGC 3120 3121 ATGCGTGAAA GGATCGAATT TCTCAATGAG GCTTCAGTGA TGAAGGAGTT CAATTGTCAC 3180 3181 CATGTGGTGC GGTTGCTGGG TGTGGTGTCC CAGGGCCAGC CGACGCTGGT CATCATGGAA 3240 3241 CTGATGACAC GAGGGGATCT CAAAAGTTAT CTCAGGTCTC TGAGGCCAGA AATAGAGAAT 3300 3301 AATCCAGTCC TCGCACCTCC AAGCCTAAGC AAGATGATCC AGATGGCTGG GGAGATTGCT 3360 3361 GATGGCATGG CATACCTCAA TGCCAACAAG TTTGTCCACA GAGACCTTGC TGCCAGGAAC 3420 3421 TGCATGGTGG CCGAAGATTT CACAGTCAAA ATTGGAGATT TCGGTATGAC AAGAGACATC 3480 3481 TATGAGACAG ACTATTACCG GAAAGGAGGC AAGGGGCTGC TGCCTGTGCG CTGGATGTCA 3540 3541 CCTGAGTCTC TCAAGGATGG AGTCTTCACC ACTCACTCTG ACGTCTGGTC CTTTGGGGTC 3600 3601 GTTCTCTGGG AGATCGCCAC GCTGGCTGAG CAGCCATACC AGGGCTTGTC CAACGAGCAA 3660 3661 GTCCTTCGCT TCGTTATGGA GGGCGGCCTT CTGGACAAGC CGGACAACTG CCCCGACATG 3720 3721 CTGTTTGAGC TGATGCGCAT GTGCTGGCAG TACAACCCCA AGATGAGGCC TTCCTTCCTG 3780 3781 GAGATCATCA GCAGCATCAA GGACGAGATG GAGCCCGGCT TCCGGGAGGT CTCCTTCTAC 3840 3841 TACAGCGAGG AGAACAAGCC GCCCGAGCCG GAGGAGCTGG ACCTGGAGCC GGAGAACATG 3900 3901 GAGAGTGTCC CCCTGGACCC GTCGGCCTCC TCGTCGTCCC TGCCTCTGCC TGACAGACTC 3960 3961 TCAGGACACA AGGCCGAGAA CGGCCCAGGC CCTGGCGTGC TGGTCCTGCG AGCCAGCTTC 4020 4021 GATGAGAGAC AGCCTTACGC GCACATGAAC GGGGGCCGCA AGAACGAGCG GGCCTTGCCT 4080 4081 CTGCCCCAGT CTTCGACCTG CTGA 4104 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Fec-3832 | Felis catus | 99.27 | 0.0 | 2574 |
| LLPS-Mup-0374 | Mustela putorius furo | 98.98 | 0.0 | 2569 |
| LLPS-Tut-2068 | Tursiops truncatus | 98.24 | 0.0 | 2546 |
| LLPS-Loa-1697 | Loxodonta africana | 97.06 | 0.0 | 2113 |
| LLPS-Dio-0065 | Dipodomys ordii | 96.32 | 0.0 | 1649 |
| LLPS-Mum-4413 | Mus musculus | 95.84 | 0.0 | 2497 |
| LLPS-Urm-1083 | Ursus maritimus | 92.03 | 0.0 | 2394 |
| LLPS-Nol-3980 | Nomascus leucogenys | 91.57 | 0.0 | 1980 |
| LLPS-Sah-0185 | Sarcophilus harrisii | 87.8 | 0.0 | 1802 |
| LLPS-Mod-1992 | Monodelphis domestica | 87.7 | 0.0 | 2355 |
| LLPS-Pes-1023 | Pelodiscus sinensis | 83.86 | 0.0 | 2243 |
| LLPS-Gaga-2523 | Gallus gallus | 83.27 | 0.0 | 2234 |
| LLPS-Tag-3528 | Taeniopygia guttata | 82.98 | 0.0 | 2255 |
| LLPS-Fia-3235 | Ficedula albicollis | 82.57 | 0.0 | 1873 |
| LLPS-Anp-0995 | Anas platyrhynchos | 82.19 | 0.0 | 2215 |
| LLPS-Ora-2782 | Ornithorhynchus anatinus | 79.67 | 0.0 | 847 |
| LLPS-Anc-0520 | Anolis carolinensis | 78.83 | 0.0 | 2092 |
| LLPS-Tar-3646 | Takifugu rubripes | 77.42 | 3e-06 | 56.6 |
| LLPS-Meg-2956 | Meleagris gallopavo | 67.7 | 0.0 | 711 |
| LLPS-Man-2108 | Macaca nemestrina | 62.23 | 0.0 | 676 |
| LLPS-Icp-2904 | Ictalurus punctatus | 61.68 | 0.0 | 1566 |
| LLPS-Lac-3729 | Latimeria chalumnae | 60.28 | 0.0 | 929 |
| LLPS-Leo-3233 | Lepisosteus oculatus | 58.99 | 0.0 | 1483 |
| LLPS-Asm-2540 | Astyanax mexicanus | 58.14 | 0.0 | 1469 |
| LLPS-Cap-3159 | Cavia porcellus | 58.09 | 0.0 | 1474 |
| LLPS-Pof-0133 | Poecilia formosa | 58.05 | 0.0 | 1442 |
| LLPS-Fud-1308 | Fukomys damarensis | 57.93 | 0.0 | 1474 |
| LLPS-Aim-1537 | Ailuropoda melanoleuca | 57.74 | 0.0 | 1456 |
| LLPS-Bot-3756 | Bos taurus | 57.59 | 0.0 | 1452 |
| LLPS-Sus-4092 | Sus scrofa | 57.54 | 0.0 | 1451 |
| LLPS-Eqc-1472 | Equus caballus | 57.53 | 0.0 | 1452 |
| LLPS-Orc-3000 | Oryctolagus cuniculus | 57.51 | 0.0 | 1454 |
| LLPS-Hos-3705 | Homo sapiens | 57.45 | 0.0 | 1463 |
| LLPS-Paa-2894 | Papio anubis | 57.38 | 0.0 | 1460 |
| LLPS-Pat-1444 | Pan troglodytes | 57.36 | 0.0 | 1457 |
| LLPS-Cas-1514 | Carlito syrichta | 57.29 | 0.0 | 1459 |
| LLPS-Maf-3909 | Macaca fascicularis | 57.17 | 0.0 | 1447 |
| LLPS-Myl-0603 | Myotis lucifugus | 57.1 | 0.0 | 1449 |
| LLPS-Ict-1579 | Ictidomys tridecemlineatus | 57.04 | 0.0 | 1448 |
| LLPS-Otg-4376 | Otolemur garnettii | 56.92 | 0.0 | 1455 |
| LLPS-Ten-3402 | Tetraodon nigroviridis | 56.81 | 0.0 | 1040 |
| LLPS-Xim-2692 | Xiphophorus maculatus | 56.8 | 0.0 | 1419 |
| LLPS-Caj-4693 | Callithrix jacchus | 56.76 | 0.0 | 1455 |
| LLPS-Scm-3919 | Scophthalmus maximus | 56.62 | 0.0 | 1421 |
| LLPS-Pap-3996 | Pan paniscus | 56.43 | 0.0 | 1416 |
| LLPS-Ran-2399 | Rattus norvegicus | 56.33 | 0.0 | 1459 |
| LLPS-Scf-3697 | Scleropages formosus | 56.33 | 0.0 | 1389 |
| LLPS-Ova-3581 | Ovis aries | 56.29 | 0.0 | 1452 |
| LLPS-Mal-2931 | Mandrillus leucophaeus | 56.16 | 0.0 | 1410 |
| LLPS-Orn-3814 | Oreochromis niloticus | 56.09 | 0.0 | 1399 |
| LLPS-Mea-4125 | Mesocricetus auratus | 55.99 | 0.0 | 1391 |
| LLPS-Dar-1804 | Danio rerio | 55.87 | 0.0 | 1449 |
| LLPS-Orl-2585 | Oryzias latipes | 55.74 | 0.0 | 1417 |
| LLPS-Cea-1544 | Cercocebus atys | 55.65 | 0.0 | 1368 |
| LLPS-Rhb-3446 | Rhinopithecus bieti | 55.61 | 0.0 | 1395 |
| LLPS-Gog-1491 | Gorilla gorilla | 55.14 | 0.0 | 1409 |
| LLPS-Gaa-1374 | Gasterosteus aculeatus | 55.07 | 0.0 | 1355 |
| LLPS-Poa-2299 | Pongo abelii | 54.94 | 0.0 | 1373 |
| LLPS-Mam-4624 | Macaca mulatta | 54.82 | 0.0 | 1155 |
| LLPS-Chs-3766 | Chlorocebus sabaeus | 54.43 | 0.0 | 1370 |
| LLPS-Aon-1424 | Aotus nancymaae | 53.94 | 0.0 | 1350 |
| LLPS-Cii-2292 | Ciona intestinalis | 53.77 | 3e-133 | 425 |
| LLPS-Xet-1869 | Xenopus tropicalis | 53.51 | 0.0 | 1339 |
| LLPS-Drm-1667 | Drosophila melanogaster | 40.43 | 1e-63 | 243 |
| LLPS-Cae-0235 | Caenorhabditis elegans | 37.11 | 5e-83 | 305 |
| LLPS-Cis-2073 | Ciona savignyi | 36.47 | 0.0 | 760 |