LLPS-Asm-2540
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Tyrosine-protein kinase receptor |
| Ensembl Gene: | ENSAMXG00000001680.2 |
| Ensembl Protein: | ENSAMXP00000001713.2 |
| Organism: | Astyanax mexicanus |
| Taxa ID: | 7994 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule, Others | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSAMXT00000001713.2 | ENSAMXP00000001713.2 |
| Ensembl | ENSAMXT00000039949.1 | ENSAMXP00000037399.1 |
| UniProt | A0A3B1J7U9, A0A3B1J7U9_ASTMX |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MQLRTVAGLL LTVCAVWNCQ QTSGEICSSK DIRNNVTNLR LLENCTVIEG HLKILLMFTT 60 61 KPEDFRGLTF PKLTVVTDYL LLFRVYGMES LSSLFPNLTV IRGNNLFFNY ALVLFEMLQL 120 121 KELGLHSLMN ITRGAVRVEK NPDLCYLSTL DWSKILDSVE DNYIVANKND GECGDVCPGM 180 181 AKGKTTCPQT TINGHFSERC WTQKHCQRMC PSSCKHRACT KDNQCCHDQC LGGCMEPSSP 240 241 RKCVACRNFL HQGECVERCP AGFYTFKGWR CVDFAFCQAL HNRCKQGKQG KGGECYEYVI 300 301 HQGACIPECP SGYTTINSTS LNCTPCAGLC PKVCMGLKTV DSVTAAQGLR GCTVLNGSLV 360 361 INIRGGNNIA AELEANLGQL EEITGYLTVR RSYALVSLSF LRKLRLIRGE VQEVGNYSFY 420 421 ALDNQNLRQL WDWSKHNLTI QQGRMFFHHN SKLCMAEIRK MEEVTGTKNR HVKNDIATKT 480 481 NGDQASCESQ VLKFTTIRTL SDKIIIKWEP FWPPDFRDLL GFMVLYKDAP YKNVTEFDGQ 540 541 DACGSNSWVI ADVDPPQRAT DGKEQQEPGY LILALKPWTQ YAIMVKTQLS ASDEHQVHGA 600 601 KSEIIYVRTN ATKPSVPLDP ISSSNSSSQI ILKWKPPNDP NGNITHYLVF CQQQPEASEL 660 661 YKFDYCQKGM KLPSRAPTQV DSGEEQKWNQ TEEHGQGGRC CACPKTEKQL KKEAEETEYR 720 721 KTFENYLHNE VFRIRPSRQR RSLVGVANQT HSDFLTTPSI PPNTSSTPSP EEEAEANKIT 780 781 QLVYAKESTV ISNLRHFTSY QIEIHACNHP TDPARCSMAA YVSARTMPED HADDIMGPIT 840 841 FEVAEYSVHI RWIEPKAPNG MIILYEVNYK RLGDTEELHH CVSRKSYITE NGCKLRVVHP 900 901 GNYTVRIRAT SLAGNGSWTE PTHFYVQDLR VDPSNMLKIV IAPVICIFLL LLMGLAGFIV 960 961 FKKKQTEGPT GRLYTSPNPE YLSPDEVYEP DEWEVPRDKI SLLRELGQGS FGMVYEGIAK 1020 1021 DIVKGEPQTH VAVKTVNESA SLRERIEFLN EASVMKAFSC HHVVRLLGVV SKGQPTLVVM 1080 1081 ELMTHGDLKS YLRCLRPESE NNPGRPPPTL KEMIQMAAEI ADGMAYLNAK KFVHRDLAAR 1140 1141 NCMVAEDFTV KIGDFGMTRD IYETDYYRKG GKGLLPVRWM APESLKDGVF TAHSDCWSFG 1200 1201 VVLWEISTLA EQPYQGLSNE QVLKFVMDGG YLDRPDNCAD RLHNLMQMCW HYNPKMRPTF 1260 1261 QEIIEMLKEE LHPSFQEMSF FYSEENKPPE SEDFDMDIEN MESIPLDPSS YSQREGSADG 1320 1321 DEGSAVGLRG SYDQHVPYTQ MNGGKKNGRI LSLPRSSPS 1359 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTTATCAA TTGCTATTTG TTCGAGTAAA GACATCAGAA ACAATGTGAC CAACCTGCGT 60 61 TTACTGGAGA ACTGCACAGT GATCGAGGGC CACCTAAAGA TCCTGTTAAT GTTCACCACG 120 121 AAACCAGAGG ACTTCCGAGG CCTGACTTTC CCCAAGCTGA CTGTGGTGAC GGACTACCTC 180 181 CTGCTGTTCC GCGTCTACGG AATGGAGAGC CTCAGCAGCC TTTTCCCGAA CTTGACTGTG 240 241 ATCCGAGGGA ACAACCTGTT CTTTAACTAC GCTCTGGTTC TGTTCGAGAT GCTGCAGCTG 300 301 AAGGAGCTCG GCCTACATAG CCTGATGAAC ATCACCCGTG GCGCTGTGCG GGTGGAGAAG 360 361 AACCCCGACC TCTGCTACCT CTCCACCCTC GACTGGTCCA AGATCCTTGA CTCTGTGGAG 420 421 GACAACTACA TTGTGGCCAA TAAGAATGAC GGAGAGTGCG GAGACGTGTG TCCCGGCATG 480 481 GCTAAAGGCA AGACCACCTG CCCTCAGACC ACCATCAACG GGCACTTCAG CGAACGCTGC 540 541 TGGACACAGA AGCACTGCCA GAGAATGTGT CCGTCGTCCT GTAAACACAG AGCCTGCACT 600 601 AAGGATAATC AGTGCTGCCA TGATCAGTGT CTGGGTGGCT GCATGGAACC AAGCTCTCCA 660 661 AGAAAGTGCG TGGCCTGCAG GAACTTCCTC CACCAGGGGG AGTGTGTGGA GAGGTGCCCA 720 721 GCTGGCTTCT ACACATTTAA AGGTTGGAGG TGTGTGGACT TCGCCTTCTG CCAGGCCCTG 780 781 CACAACAGGT GCAAGCAGGG CAAGCAGGGA AAAGGCGGCG AGTGCTACGA GTATGTCATC 840 841 CACCAGGGGG CGTGCATCCC AGAGTGTCCC TCAGGCTATA CCACCATCAA CTCCACCTCG 900 901 TTGAACTGTA CCCCGTGTGC TGGTTTGTGT CCTAAAGTGT GTATGGGACT GAAGACCGTG 960 961 GACTCTGTGA CGGCAGCACA GGGGCTCAGA GGCTGCACGG TTCTGAACGG CAGTCTGGTC 1020 1021 ATCAATATCC GAGGAGGAAA TAACATAGCA GCAGAACTGG AAGCTAACCT GGGTCAGCTA 1080 1081 GAGGAAATTA CAGGCTATCT CACTGTCCGT CGATCGTACG CCCTCGTGTC TCTCTCTTTC 1140 1141 CTCCGCAAAC TCCGACTCAT CCGTGGTGAA GTGCAGGAAG TGGGGAACTA CTCCTTCTAC 1200 1201 GCTCTGGATA ATCAGAACCT GCGTCAGCTC TGGGACTGGT CCAAGCACAA CCTGACAATC 1260 1261 CAGCAGGGTC GCATGTTCTT CCACCACAAC TCCAAACTCT GCATGGCTGA GATACGCAAG 1320 1321 ATGGAGGAGG TCACCGGGAC CAAGAACCGG CACGTCAAAA ACGACATCGC CACCAAGACT 1380 1381 AACGGAGACC AGGCTTCCTG TGAGAGTCAG GTGCTGAAGT TCACAACGAT CCGCACTCTC 1440 1441 TCCGACAAAA TCATCATCAA ATGGGAGCCG TTCTGGCCTC CGGACTTCAG AGACCTGCTG 1500 1501 GGCTTCATGG TTCTCTACAA AGATGCGCCA TACAAAAACG TGACCGAGTT TGATGGGCAA 1560 1561 GACGCATGCG GCTCCAACAG CTGGGTAATT GCAGATGTGG ATCCTCCACA GAGAGCCACA 1620 1621 GACGGTAAAG AGCAGCAGGA GCCAGGATAC CTCATACTGG CTCTAAAGCC CTGGACCCAA 1680 1681 TATGCAATCA TGGTGAAAAC ACAGCTCTCT GCTTCAGACG AACACCAGGT CCACGGAGCC 1740 1741 AAGAGCGAGA TCATCTACGT CCGCACCAAT GCCACCAAGC CGTCTGTGCC GCTGGACCCA 1800 1801 ATCTCTTCCT CCAACTCCTC ATCTCAGATT ATACTGAAGT GGAAGCCCCC CAACGACCCC 1860 1861 AACGGCAACA TCACACACTA CCTGGTGTTC TGCCAGCAGC AGCCTGAGGC CAGTGAGCTC 1920 1921 TACAAGTTCG ACTACTGTCA GAAAGGTATG AAGCTGCCGT CTCGAGCCCC GACACAGGTG 1980 1981 GACAGTGGCG AAGAGCAGAA GTGGAATCAG ACTGAGGAAC ACGGTCAGGG AGGACGCTGC 2040 2041 TGCGCCTGTC CCAAAACTGA GAAGCAGCTG AAGAAGGAGG CTGAGGAGAC GGAGTACCGC 2100 2101 AAGACCTTCG AGAACTACCT GCACAACGAG GTGTTCAGAA TCAGGCCGTC CCGACAGCGC 2160 2161 AGGTCCCTCG TGGGTGTGGC TAACCAGACC CATTCTGACT TTCTCACCAC ACCCTCCATC 2220 2221 CCACCCAACA CCTCATCCAC CCCCAGCCCG GAGGAGGAAG CCGAGGCCAA TAAGATCACA 2280 2281 CAGCTCGTCT ACGCTAAAGA GTCCACAGTC ATCTCCAACC TCAGGCACTT CACCAGCTAC 2340 2341 CAGATCGAAA TCCACGCCTG CAACCACCCC ACAGACCCTG CCCGCTGCAG CATGGCCGCA 2400 2401 TACGTCAGTG CACGCACCAT GCCGGAGGAT CATGCTGACG ACATCATGGG TCCAATCACC 2460 2461 TTTGAGGTTG CGGAGTATTC TGTTCATATC AGGTGGATCG AGCCAAAAGC TCCCAATGGC 2520 2521 ATGATCATCC TCTACGAGGT CAACTACAAA AGGCTGGGAG ATACAGAGTT GCATCACTGC 2580 2581 GTGTCCAGAA AGAGCTATAT CACGGAAAAT GGCTGTAAGC TAAGAGTGGT GCATCCTGGG 2640 2641 AATTACACTG TTCGGATTCG AGCCACTTCA CTGGCAGGAA ACGGATCCTG GACAGAACCC 2700 2701 ACACACTTCT ACGTGCAGGA CCTCCAGATC ATTCTAAAAG TGCAAACTGA AGGACCAACA 2760 2761 GGACGCCTGT ACACATCACC CAACCCAGAG TACCTCAGCC CAGATGAAGT GTACGAGCCG 2820 2821 GATGAGTGGG AGGTTCCCCG GGATAAGATC AGTCTGCTGC GTGAGCTGGG GCAGGGCTCG 2880 2881 TTCGGTATGG TGTATGAGGG TATAGCGAAG GACATTGTAA AGGGGGAGCC GCAGACCCAC 2940 2941 GTCGCTGTCA AAACTGTGAA CGAGTCAGCC AGCCTGAGAG AGCGCATCGA GTTCCTCAAC 3000 3001 GAGGCATCTG TCATGAAGGC CTTCAGCTGC CACCATGTGG TGAGACTGCT GGGTGTGGTT 3060 3061 TCCAAAGGCC AGCCCACCCT GGTGGTGATG GAGCTAATGA CCCATGGTGA CCTGAAAAGC 3120 3121 TACCTGCGTT GTCTCAGGCC TGAATCCGAG AATAACCCCG GCCGGCCGCC CCCCACACTG 3180 3181 AAGGAGATGA TCCAGATGGC TGCGGAGATC GCAGATGGCA TGGCCTACCT GAACGCCAAG 3240 3241 AAGTTTGTGC ACAGAGACCT GGCTGCCAGA AACTGCATGG TGGCTGAGGA TTTCACAGTT 3300 3301 AAGATTGGAG ATTTCGGTAT GACCAGAGAC ATCTATGAGA CAGATTACTA CAGGAAAGGG 3360 3361 GGGAAGGGGC TCCTCCCCGT CAGGTGGATG GCCCCAGAAT CTCTGAAGGA CGGAGTCTTT 3420 3421 ACTGCACACT CAGACTGCTG GTCGTTTGGT GTGGTGCTGT GGGAGATCAG CACTTTAGCT 3480 3481 GAGCAGCCGT ATCAGGGTCT GTCCAACGAG CAGGTGTTGA AATTTGTGAT GGACGGAGGA 3540 3541 TACCTGGACC GGCCGGACAA CTGTGCTGAC AGACTACACA ATCTGATGCA GATGTGCTGG 3600 3601 CACTACAACC CCAAGATGCG GCCCACCTTC CAGGAGATCA TCGAGATGCT GAAGGAGGAG 3660 3661 CTGCACCCGT CTTTCCAGGA GATGTCCTTC TTCTACAGCG AGGAGAACAA GCCCCCGGAG 3720 3721 AGCGAGGACT TTGACATGGA CATAGAGAAC ATGGAGAGCA TCCCTCTGGA CCCGTCGTCC 3780 3781 TACTCCCAGC GCGAGGGCAG CGCCGACGGG GACGAGGGCT CGGCCGTGGG CCTGCGGGGC 3840 3841 AGCTACGACC AGCATGTTCC GTACACACAG ATGAACGGGG GCAAGAAAAA CGGACGCATT 3900 3901 TTATCGCTCC CTCGCTCCAG CCCCTCTTAA 3930 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Pof-0133 | Poecilia formosa | 82.55 | 0.0 | 2307 |
| LLPS-Scm-3919 | Scophthalmus maximus | 82.1 | 0.0 | 2333 |
| LLPS-Leo-3233 | Lepisosteus oculatus | 82.07 | 0.0 | 2333 |
| LLPS-Ten-3402 | Tetraodon nigroviridis | 81.66 | 0.0 | 1714 |
| LLPS-Scf-3697 | Scleropages formosus | 80.39 | 0.0 | 2184 |
| LLPS-Orl-2585 | Oryzias latipes | 79.56 | 0.0 | 2251 |
| LLPS-Orn-3814 | Oreochromis niloticus | 74.41 | 0.0 | 2102 |
| LLPS-Dar-1804 | Danio rerio | 74.25 | 0.0 | 2077 |
| LLPS-Lac-3729 | Latimeria chalumnae | 73.25 | 0.0 | 1261 |
| LLPS-Gaa-1374 | Gasterosteus aculeatus | 73.03 | 0.0 | 2050 |
| LLPS-Xim-2692 | Xiphophorus maculatus | 72.14 | 0.0 | 2033 |
| LLPS-Orc-3000 | Oryctolagus cuniculus | 69.72 | 0.0 | 1934 |
| LLPS-Cap-3159 | Cavia porcellus | 69.71 | 0.0 | 1929 |
| LLPS-Aim-1537 | Ailuropoda melanoleuca | 69.36 | 0.0 | 1931 |
| LLPS-Cas-1514 | Carlito syrichta | 69.27 | 0.0 | 1930 |
| LLPS-Ict-1579 | Ictidomys tridecemlineatus | 69.12 | 0.0 | 1922 |
| LLPS-Ova-3581 | Ovis aries | 69.02 | 0.0 | 1920 |
| LLPS-Eqc-1472 | Equus caballus | 69.02 | 0.0 | 1927 |
| LLPS-Sus-4092 | Sus scrofa | 68.95 | 0.0 | 1923 |
| LLPS-Otg-4376 | Otolemur garnettii | 68.95 | 0.0 | 1916 |
| LLPS-Myl-0603 | Myotis lucifugus | 68.92 | 0.0 | 1917 |
| LLPS-Bot-3756 | Bos taurus | 68.9 | 0.0 | 1917 |
| LLPS-Paa-2894 | Papio anubis | 68.87 | 0.0 | 1927 |
| LLPS-Hos-3705 | Homo sapiens | 68.87 | 0.0 | 1922 |
| LLPS-Pat-1444 | Pan troglodytes | 68.83 | 0.0 | 1920 |
| LLPS-Maf-3909 | Macaca fascicularis | 68.8 | 0.0 | 1920 |
| LLPS-Caj-4693 | Callithrix jacchus | 68.45 | 0.0 | 1927 |
| LLPS-Fud-1308 | Fukomys damarensis | 68.34 | 0.0 | 1915 |
| LLPS-Ran-2399 | Rattus norvegicus | 67.58 | 0.0 | 1912 |
| LLPS-Rhb-3446 | Rhinopithecus bieti | 67.46 | 0.0 | 1851 |
| LLPS-Pap-3996 | Pan paniscus | 67.36 | 0.0 | 1848 |
| LLPS-Gog-1491 | Gorilla gorilla | 67.06 | 0.0 | 1843 |
| LLPS-Cea-1544 | Cercocebus atys | 66.35 | 0.0 | 1806 |
| LLPS-Poa-2299 | Pongo abelii | 66.3 | 0.0 | 1809 |
| LLPS-Mam-4624 | Macaca mulatta | 66.07 | 0.0 | 1562 |
| LLPS-Chs-3766 | Chlorocebus sabaeus | 65.05 | 0.0 | 1795 |
| LLPS-Man-2108 | Macaca nemestrina | 64.74 | 0.0 | 1750 |
| LLPS-Aon-1424 | Aotus nancymaae | 64.66 | 0.0 | 1745 |
| LLPS-Xet-1869 | Xenopus tropicalis | 63.69 | 0.0 | 1708 |
| LLPS-Meg-2956 | Meleagris gallopavo | 62.72 | 0.0 | 667 |
| LLPS-Anp-0995 | Anas platyrhynchos | 59.57 | 0.0 | 1599 |
| LLPS-Gaga-2523 | Gallus gallus | 59.28 | 0.0 | 1604 |
| LLPS-Sah-0185 | Sarcophilus harrisii | 59.01 | 0.0 | 1230 |
| LLPS-Tag-3528 | Taeniopygia guttata | 58.92 | 0.0 | 1610 |
| LLPS-Mod-1992 | Monodelphis domestica | 58.6 | 0.0 | 1579 |
| LLPS-Pes-1023 | Pelodiscus sinensis | 58.51 | 0.0 | 1598 |
| LLPS-Anc-0520 | Anolis carolinensis | 58.46 | 0.0 | 1569 |
| LLPS-Mum-4413 | Mus musculus | 58.35 | 0.0 | 1531 |
| LLPS-Fia-3235 | Ficedula albicollis | 58.35 | 0.0 | 1344 |
| LLPS-Caf-3254 | Canis familiaris | 58.22 | 0.0 | 1526 |
| LLPS-Mup-0374 | Mustela putorius furo | 57.93 | 0.0 | 1529 |
| LLPS-Tut-2068 | Tursiops truncatus | 57.93 | 0.0 | 1519 |
| LLPS-Fec-3832 | Felis catus | 57.85 | 0.0 | 1526 |
| LLPS-Dio-0065 | Dipodomys ordii | 57.74 | 0.0 | 1031 |
| LLPS-Loa-1697 | Loxodonta africana | 57.23 | 0.0 | 1283 |
| LLPS-Nol-3980 | Nomascus leucogenys | 54.47 | 0.0 | 1219 |
| LLPS-Urm-1083 | Ursus maritimus | 54.47 | 0.0 | 1423 |
| LLPS-Mal-2931 | Mandrillus leucophaeus | 52.83 | 0.0 | 1326 |
| LLPS-Icp-2904 | Ictalurus punctatus | 52.68 | 0.0 | 1375 |
| LLPS-Mea-4125 | Mesocricetus auratus | 51.97 | 0.0 | 1320 |
| LLPS-Tar-3646 | Takifugu rubripes | 51.19 | 0.0 | 1398 |
| LLPS-Ora-2782 | Ornithorhynchus anatinus | 49.02 | 0.0 | 1079 |
| LLPS-Cii-2292 | Ciona intestinalis | 48.38 | 1e-139 | 442 |
| LLPS-Drm-1667 | Drosophila melanogaster | 42.45 | 6e-65 | 247 |
| LLPS-Cae-0235 | Caenorhabditis elegans | 38.61 | 2e-90 | 328 |
| LLPS-Cis-2073 | Ciona savignyi | 37.47 | 0.0 | 829 |