• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Asm-3918

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Ensembl Gene: ENSAMXG00000013857.2
Ensembl Protein: ENSAMXP00000014254.2
Organism: Astyanax mexicanus
Taxa ID: 7994
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MEKRGEAKIS  DAISTQYPVV  DHEFDAVVVG  AGGAGLRAAF  GLSEAGFNTA  CVTKLFPTRS  60
61    HTVAAQGGIN  AALGNMEEDD  WRWHFYDTVK  GSDWLGDQDA  IHYMTEQAPA  AVVELENFGM  120
121   PFSRTEDGKI  YQRAFGGQSL  KYGKGGQAHR  CCCVADRTGH  SLLHTLYGRS  LRYDTSYFVE  180
181   YFALDLLMED  GECKGVIALC  MEDGSIHRIR  AKNTVIATGG  YGRTYFSCTS  AHTSTGDGNA  240
241   MVTRAGLPCQ  DLEFVQFHPT  GIYGAGCLIT  EGCRGEGGIL  INSEGERFME  RYAPNAKDLA  300
301   SRDVVSRSMT  IEIREGRGVG  PEKDHVYLQL  HHLPPQQLAT  RLPGISETAM  IFAGVDVTKE  360
361   PIPVLPTVHY  NMGGIPTNYK  GQAITYKDGK  DQVVPGLYAC  GEAGCASVHG  ANRLGANSLL  420
421   DLVVFGRACA  LTIAENDKPG  EKLSPLKPNA  GEESVANLDK  IRFAKGSMRT  SEIRLNMQKT  480
481   MQAHAAVFRT  GDVLKEGCVK  MDAIYQTLDD  VKTFDRGIVW  NTDLVETLEL  QNLMLNAVQT  540
541   INAAEARKES  RGAHAREDFK  ERVDEYDYSK  PLQGQEKKPF  EQHWRKHTLS  YVDPKTGKVT  600
601   LEYRPVIDDS  LNNEDCAAIP  PAIRSY  626
Nucleotide CDS Sequence (FASTA)
1     TTCTCCATTC  ATGGAAAAAA  GAGGAGAAGC  TGCTTTGTGT  TACAGATATC  CACACAGTAT  60
61    CCAGTGGTAG  ATCATGAGTT  TGATGCTGTG  GTGGTGGGAG  CAGGAGGTGC  TGGATTACGT  120
121   GCAGCATTTG  GGCTGTCAGA  GGCTGGCTTC  AATACAGCAT  GCGTCACCAA  ACTGTTCCCC  180
181   ACTCGCTCTC  ATACTGTGGC  TGCACAGGGT  GGAATCAATG  CAGCTCTCGG  CAACATGGAG  240
241   GAAGATGACT  GGCGGTGGCA  TTTTTATGAC  ACGGTTAAAG  GATCCGATTG  GTTGGGAGAT  300
301   CAAGATGCCA  TTCACTATAT  GACTGAGCAA  GCCCCTGCTG  CAGTGGTTGA  GCTGGAGAAC  360
361   TTCGGTATGC  CCTTCAGTCG  TACAGAGGAT  GGAAAGATCT  ACCAGCGTGC  TTTCGGAGGG  420
421   CAGAGTTTGA  AGTATGGAAA  AGGAGGACAG  GCTCACAGGT  GCTGCTGTGT  GGCTGACAGG  480
481   ACGGGTCACT  CTCTTCTGCA  CACTCTCTAT  GGACGGTCTC  TGAGGTACGA  CACAAGCTAC  540
541   TTTGTGGAGT  ATTTTGCTCT  GGACCTGCTG  ATGGAAGATG  GAGAGTGTAA  AGGAGTCATT  600
601   GCACTCTGCA  TGGAGGATGG  ATCCATCCAC  CGCATCAGAG  CCAAGAACAC  AGTAATCGCC  660
661   ACAGGTGGTT  ATGGCCGCAC  ATATTTCAGC  TGCACCTCAG  CCCACACTAG  CACAGGAGAT  720
721   GGTAATGCCA  TGGTTACACG  TGCTGGCCTG  CCGTGTCAGG  ACCTGGAGTT  TGTTCAGTTC  780
781   CACCCCACAG  GTATCTATGG  AGCTGGTTGC  CTGATCACAG  AAGGCTGTCG  TGGAGAAGGT  840
841   GGAATTTTGA  TCAACAGTGA  AGGTGAACGG  TTTATGGAAC  GCTACGCTCC  AAATGCTAAA  900
901   GACTTGGCCT  CCAGGGATGT  GGTGTCGCGC  TCCATGACTA  TTGAAATTCG  CGAGGGAAGA  960
961   GGTGTAGGGC  CAGAGAAGGA  CCATGTTTAT  CTGCAGCTCC  ACCACCTTCC  TCCTCAGCAG  1020
1021  CTGGCTACCC  GCCTGCCCGG  AATCTCAGAA  ACTGCTATGA  TATTTGCTGG  GGTGGATGTC  1080
1081  ACCAAAGAGC  CTATCCCTGT  CTTGCCCACA  GTCCACTACA  ACATGGGAGG  CATTCCCACC  1140
1141  AACTACAAGG  GACAGGCTAT  TACTTACAAA  GATGGTAAAG  ACCAGGTAGT  GCCAGGGTTA  1200
1201  TATGCATGTG  GAGAAGCTGG  CTGTGCCTCT  GTACATGGTG  CCAATCGCCT  GGGAGCCAAC  1260
1261  TCTTTGCTGG  ATCTGGTTGT  GTTTGGTCGT  GCCTGTGCCC  TGACCATTGC  TGAGAATGAT  1320
1321  AAGCCAGGAG  AGAAGCTTTC  ACCCCTGAAA  CCAAACGCAG  GAGAGGAGTC  AGTTGCTAAT  1380
1381  TTGGACAAAA  TCCGCTTTGC  TAAAGGCAGT  ATGAGGACCT  CTGAGATTAG  GCTCAATATG  1440
1441  CAGAAGACCA  TGCAGGCCCA  TGCTGCTGTA  TTTCGTACTG  GAGATGTTCT  AAAAGAGGGA  1500
1501  TGTGTCAAAA  TGGATGCCAT  CTATCAGACA  TTGGATGACG  TCAAAACATT  TGACAGAGTT  1560
1561  TGGAGCACAA  CTTTAGAGCT  CCAGAACCTG  ATGCTCAATG  CTGTGCAGAC  TATCAACGCA  1620
1621  GCTGAGGCCC  GCAAAGAAAG  CAGGGGGGCT  CATGCCCGTG  AGGATTTCAA  GGAACGTGTG  1680
1681  GATGAGTATG  ATTACTCCAA  GCCCCTACAG  GGACAAGAGA  AGAAGCCTTT  TGAGCAGCAC  1740
1741  TGGAGGAAGC  ACACACTCTC  TTATGTAGAT  CCTAAAACAG  GAAAGGTCAC  TCTGGAATAC  1800
1801  AGGCCTGTGA  TTGATGACTC  TCTGAACAAT  GAAGACTGTG  CTGCTATTCC  TCCTGCCATC  1860
1861  CGTTCCTATT  AA  1872

▼ KEYWORD

ID
Family
Complete proteome
Electron transport
FAD
Flavoprotein
Membrane
Oxidoreductase
Reference proteome
Transit peptide
Transport
Tricarboxylic acid cycle

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Mitochondrial inner membrane
Molecular Function
Flavin adenine dinucleotide binding
Molecular Function
Succinate dehydrogenase (ubiquinone) activity
Biological Process
Electron transport chain
Biological Process
Tricarboxylic acid cycle

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Icp-0244Ictalurus punctatus95.190.01192
LLPS-Mal-1109Mandrillus leucophaeus94.011e-135 404
LLPS-Dar-3303Danio rerio93.910.01176
LLPS-Gaa-3819Gasterosteus aculeatus93.260.01170
LLPS-Orl-0189Oryzias latipes93.110.01164
LLPS-Pes-1080Pelodiscus sinensis92.692e-165 482
LLPS-Tar-3095Takifugu rubripes92.630.01167
LLPS-Orn-3153Oreochromis niloticus92.470.01160
LLPS-Scm-0550Scophthalmus maximus92.310.01158
LLPS-Xim-2114Xiphophorus maculatus92.150.01159
LLPS-Ten-0393Tetraodon nigroviridis91.550.01152
LLPS-Pof-3913Poecilia formosa91.210.01148
LLPS-Scf-4072Scleropages formosus90.870.01138
LLPS-Rhb-1638Rhinopithecus bieti89.712e-96 302
LLPS-Orc-1339Oryctolagus cuniculus88.260.0 931
LLPS-Bot-4736Bos taurus88.210.01030
LLPS-Anc-1169Anolis carolinensis88.160.01115
LLPS-Tut-0157Tursiops truncatus88.140.01108
LLPS-Mea-2951Mesocricetus auratus88.140.01111
LLPS-Tag-0573Taeniopygia guttata88.00.01102
LLPS-Mum-3932Mus musculus87.980.01104
LLPS-Sus-0787Sus scrofa87.980.01109
LLPS-Gaga-3798Gallus gallus87.840.01105
LLPS-Caf-1091Canis familiaris87.820.01109
LLPS-Fec-3903Felis catus87.820.01109
LLPS-Fia-3058Ficedula albicollis87.680.01095
LLPS-Mam-1257Macaca mulatta87.660.01107
LLPS-Pap-4181Pan paniscus87.660.01103
LLPS-Urm-1962Ursus maritimus87.660.01108
LLPS-Pat-1044Pan troglodytes87.660.01105
LLPS-Hos-4087Homo sapiens87.660.01105
LLPS-Cap-2413Cavia porcellus87.50.01104
LLPS-Loa-1764Loxodonta africana87.50.01107
LLPS-Aim-2528Ailuropoda melanoleuca87.50.01107
LLPS-Anp-0248Anas platyrhynchos87.40.01097
LLPS-Mod-3506Monodelphis domestica87.360.01107
LLPS-Aon-0734Aotus nancymaae87.340.01102
LLPS-Caj-3812Callithrix jacchus87.340.01103
LLPS-Sah-3756Sarcophilus harrisii87.20.01098
LLPS-Ran-2990Rattus norvegicus87.180.01103
LLPS-Myl-1328Myotis lucifugus87.180.01098
LLPS-Poa-2207Pongo abelii87.170.01021
LLPS-Otg-4106Otolemur garnettii87.020.01095
LLPS-Mup-1893Mustela putorius furo86.930.01004
LLPS-Ict-4068Ictidomys tridecemlineatus86.860.01100
LLPS-Dio-3917Dipodomys ordii86.860.01102
LLPS-Eqc-1712Equus caballus86.730.01102
LLPS-Ova-0484Ovis aries86.70.01080
LLPS-Ora-3364Ornithorhynchus anatinus86.70.01095
LLPS-Cis-1891Ciona savignyi86.015e-172 500
LLPS-Leo-3513Lepisosteus oculatus85.271e-167 498
LLPS-Meg-3352Meleagris gallopavo84.80.01051
LLPS-Lac-1320Latimeria chalumnae84.660.01047
LLPS-Maf-1168Macaca fascicularis84.170.0 997
LLPS-Paa-3263Papio anubis80.190.0 705
LLPS-Vir-1979Vigna radiata79.860.0 657
LLPS-Cii-2338Ciona intestinalis77.860.0 830
LLPS-Drm-1816Drosophila melanogaster77.60.0 963
LLPS-Gog-4025Gorilla gorilla75.850.0 615
LLPS-Man-2863Macaca nemestrina72.350.0 872
LLPS-Cae-0808Caenorhabditis elegans71.860.0 893
LLPS-Abg-0717Absidia glauca71.590.0 868
LLPS-Sot-1828Solanum tuberosum71.50.0 853
LLPS-Sol-1154Solanum lycopersicum71.340.0 850
LLPS-Arl-2707Arabidopsis lyrata71.010.0 850
LLPS-Brn-0204Brassica napus70.920.0 847
LLPS-Trr-0211Trichoderma reesei70.870.0 854
LLPS-Mao-0513Magnaporthe oryzae70.870.0 863
LLPS-Map-0688Magnaporthe poae70.870.0 853
LLPS-Coc-2095Corchorus capsularis70.850.0 848
LLPS-Orbr-1879Oryza brachyantha70.820.0 842
LLPS-Usm-1070Ustilago maydis70.750.0 845
LLPS-Art-0648Arabidopsis thaliana70.680.0 847
LLPS-Mua-0191Musa acuminata70.680.0 843
LLPS-Sei-1712Setaria italica70.660.0 848
LLPS-Gor-1775Gossypium raimondii70.640.0 840
LLPS-Brr-2931Brassica rapa70.590.0 842
LLPS-Brd-1086Brachypodium distachyon70.590.0 839
LLPS-Viv-1303Vitis vinifera70.570.0 845
LLPS-Gag-1202Gaeumannomyces graminis70.550.0 848
LLPS-Prp-0627Prunus persica70.520.0 844
LLPS-Pot-2711Populus trichocarpa70.520.0 842
LLPS-Sem-1847Selaginella moellendorffii70.50.0 850
LLPS-Spr-1410Sporisorium reilianum70.420.0 843
LLPS-Crn-0769Cryptococcus neoformans70.420.0 857
LLPS-Chr-1243Chlamydomonas reinhardtii70.410.0 851
LLPS-Lem-0658Leptosphaeria maculans70.390.0 854
LLPS-Mae-2474Manihot esculenta70.360.0 841
LLPS-Mel-0652Melampsora laricipopulina70.340.0 850
LLPS-Pytr-1453Pyrenophora triticirepentis70.320.0 852
LLPS-Pyt-0302Pyrenophora teres70.320.0 852
LLPS-Hea-0159Helianthus annuus70.270.0 847
LLPS-Org-0766Oryza glaberrima70.260.0 852
LLPS-Amt-2007Amborella trichopoda70.260.0 832
LLPS-Met-1965Medicago truncatula70.240.0 842
LLPS-Orr-1524Oryza rufipogon70.210.0 851
LLPS-Ors-1619Oryza sativa70.210.0 851
LLPS-Orgl-1280Oryza glumaepatula70.210.0 851
LLPS-Ori-2287Oryza indica70.210.0 851
LLPS-Orni-0995Oryza nivara70.210.0 851
LLPS-Tru-0996Triticum urartu70.20.0 835
LLPS-Orm-1021Oryza meridionalis70.160.0 847
LLPS-Bro-1010Brassica oleracea70.160.0 847
LLPS-Thc-1555Theobroma cacao70.110.0 848
LLPS-Orp-1165Oryza punctata70.10.0 853
LLPS-Scc-1207Schizosaccharomyces cryophilus70.10.0 845
LLPS-Orb-2386Oryza barthii70.10.0 851
LLPS-Asfu-0063Aspergillus fumigatus69.920.0 833
LLPS-Nef-1124Neosartorya fischeri69.920.0 834
LLPS-Asc-0458Aspergillus clavatus69.920.0 832
LLPS-Trv-1605Trichoderma virens69.90.0 847
LLPS-Beb-0486Beauveria bassiana69.90.0 832
LLPS-Nec-0816Neurospora crassa69.90.0 848
LLPS-Phn-1091Phaeosphaeria nodorum69.760.0 835
LLPS-Asni-1345Aspergillus niger69.760.0 837
LLPS-Scj-0025Schizosaccharomyces japonicus69.710.0 846
LLPS-Ast-0888Aspergillus terreus69.590.0 829
LLPS-Fuo-1183Fusarium oxysporum69.580.0 840
LLPS-Dos-1554Dothistroma septosporum69.580.0 843
LLPS-Phv-0726Phaseolus vulgaris69.520.0 842
LLPS-Zem-0924Zea mays69.490.0 846
LLPS-Sob-2124Sorghum bicolor69.490.0 847
LLPS-Aso-1357Aspergillus oryzae69.480.0 831
LLPS-Asf-1276Aspergillus flavus69.480.0 831
LLPS-Cus-0848Cucumis sativus69.470.0 837
LLPS-Cea-3440Cercocebus atys69.460.0 578
LLPS-Lep-0579Leersia perrieri69.450.0 832
LLPS-Via-1662Vigna angularis69.430.0 825
LLPS-Asn-1155Aspergillus nidulans69.430.0 833
LLPS-Fuv-0067Fusarium verticillioides69.420.0 840
LLPS-Coo-1357Colletotrichum orbiculare69.420.0 831
LLPS-Glm-2850Glycine max69.350.0 837
LLPS-Blg-1119Blumeria graminis69.330.0 842
LLPS-Tra-2726Triticum aestivum69.330.0 843
LLPS-Php-2517Physcomitrella patens69.330.0 833
LLPS-Miv-1589Microbotryum violaceum69.240.0 827
LLPS-Pug-1004Puccinia graminis69.230.0 840
LLPS-Dac-2221Daucus carota69.220.0 831
LLPS-Cogr-1569Colletotrichum graminicola69.090.0 827
LLPS-Zyt-1286Zymoseptoria tritici68.930.0 841
LLPS-Osl-1057Ostreococcus lucimarinus68.90.0 817
LLPS-Tum-1234Tuber melanosporum68.840.0 759
LLPS-Ved-0165Verticillium dahliae68.770.0 833
LLPS-Scp-0948Schizosaccharomyces pombe68.710.0 843
LLPS-Hov-2121Hordeum vulgare68.670.0 785
LLPS-Chc-0519Chondrus crispus68.50.0 828
LLPS-Gas-1321Galdieria sulphuraria68.350.0 844
LLPS-Asg-0871Ashbya gossypii67.910.0 828
LLPS-Sac-1428Saccharomyces cerevisiae67.70.0 831
LLPS-Cog-0639Colletotrichum gloeosporioides67.640.0 816
LLPS-Yal-0932Yarrowia lipolytica66.670.0 806
LLPS-Put-1035Puccinia triticina66.320.0 714
LLPS-Cym-0357Cyanidioschyzon merolae65.980.0 820
LLPS-Kop-0421Komagataella pastoris65.70.0 810