LLPS-Art-0388
VHA-H

▼ OVERVIEW

Status: Reviewed
Protein Name: V-type proton ATPase subunit H
Gene Name: VHA-H, At3g42050, F4M19_10
Ensembl Gene: AT3G42050
Ensembl Protein: AT3G42050.1
Organism: Arabidopsis thaliana
Taxa ID: 3702
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateDescriptionTissue/CellPMIDs
Nucleolus
"...We identified 1602 proteins in the nucleolar and 2544 proteins in the nuclear fraction with an overlap of 1429 proteins."
Arabidopsis thaliana cells26980300

▼ FUNCTION

Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity).

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MDQAELSIEQ  VLKRDIPWET  YMNTKLVSAK  GLQLLRRYDK  KPESARAQLL  DEDGPAYVHL  60
61    FVSILRDIFK  EETVEYVLAL  IYEMLSANPT  RARLFHDESL  ANEDTYEPFL  RLLWKGNWFI  120
121   QEKSCKILAW  IISARPKAGN  AVIGNGIDDV  LKGLVEWLCA  QLKQPSHPTR  GVPIAISCLS  180
181   SLLKEPVVRS  SFVQADGVKL  LVPLISPAST  QQSIQLLYET  CLCIWLLSYY  EPAIEYLATS  240
241   RTMQRLTEVV  KHSTKEKVVR  VVILTFRNLL  PKGTFGAQMV  DLGLPHIIHS  LKTQAWSDED  300
301   LLDALNQLEE  GLKDKIKKLS  SFDKYKQEVL  LGHLDWNPMH  KETNFWRENV  TCFEENDFQI  360
361   LRVLLTILDT  SSDPRSLAVA  CFDISQFIQY  HAAGRVIVAD  LKAKERVMKL  INHENAEVTK  420
421   NAILCIQRLL  LGAKYASFLQ  A  441
Nucleotide CDS Sequence (FASTA)
1     ATGGATCAGG  CGGAGCTGAG  TATAGAGCAG  GTATTGAAAA  GGGACATTCC  ATGGGAGACT  60
61    TACATGAACA  CTAAGCTGGT  TTCAGCTAAA  GGTCTCCAGC  TCTTAAGGCG  CTATGATAAA  120
121   AAACCTGAAA  GTGCTAGGGC  ACAGTTGCTC  GATGAAGATG  GTCCAGCTTA  TGTTCATCTC  180
181   TTTGTTAGCA  TCTTACGTGA  TATATTCAAG  GAAGAAACTG  TCGAATATGT  TTTGGCTTTG  240
241   ATTTATGAAA  TGCTCTCAGC  AAACCCAACA  CGAGCTCGAT  TATTCCATGA  TGAATCTTTG  300
301   GCAAATGAGG  ATACTTATGA  GCCTTTCTTG  AGGTTGCTTT  GGAAGGGAAA  TTGGTTCATT  360
361   CAAGAAAAAA  GCTGTAAGAT  CCTTGCCTGG  ATAATAAGTG  CTAGGCCAAA  AGCTGGTAAT  420
421   GCTGTTATTG  GTAATGGAAT  TGATGATGTT  CTCAAGGGGT  TGGTGGAATG  GCTTTGTGCT  480
481   CAGTTGAAGC  AACCTTCTCA  TCCTACTCGT  GGTGTTCCAA  TTGCAATCAG  CTGCCTGTCG  540
541   TCACTGCTTA  AGGAACCTGT  TGTCAGATCG  TCATTTGTTC  AGGCAGATGG  GGTGAAGTTA  600
601   CTTGTCCCTT  TAATTTCCCC  AGCATCCACT  CAGCAGTCTA  TCCAGCTTCT  GTATGAAACA  660
661   TGTCTCTGCA  TCTGGCTTCT  GTCCTATTAT  GAACCTGCAA  TAGAGTACTT  GGCAACATCG  720
721   AGGACAATGC  AAAGGCTCAC  GGAAGTGGTT  AAGCACTCGA  CTAAGGAAAA  GGTTGTCAGG  780
781   GTGGTCATAT  TGACATTCAG  GAACCTTCTT  CCAAAAGGTA  CATTTGGTGC  CCAGATGGTT  840
841   GATCTTGGAC  TCCCACATAT  TATCCACAGT  CTAAAAACAC  AAGCATGGAG  TGACGAGGAC  900
901   TTGCTGGATG  CACTGAACCA  ACTAGAAGAA  GGGCTAAAAG  ACAAGATCAA  GAAATTGAGT  960
961   TCCTTTGATA  AATATAAGCA  AGAGGTGCTC  CTTGGCCATC  TTGACTGGAA  CCCAATGCAC  1020
1021  AAGGAGACCA  ATTTCTGGCG  TGAGAATGTC  ACATGCTTTG  AGGAGAACGA  CTTCCAGATA  1080
1081  CTCAGGGTCC  TCCTCACAAT  CCTGGACACC  TCAAGTGATC  CCAGATCATT  GGCGGTGGCA  1140
1141  TGCTTTGATA  TCTCACAGTT  CATACAATAC  CATGCAGCGG  GGAGAGTGAT  TGTAGCAGAC  1200
1201  CTCAAGGCAA  AAGAGCGAGT  GATGAAGCTG  ATAAACCACG  AGAACGCTGA  GGTGACCAAG  1260
1261  AACGCTATCT  TGTGCATTCA  GAGGCTTCTC  CTGGGTGCCA  AGTACGCTAG  CTTCTTGCAA  1320
1321  GCTTGA  1326

▼ KEYWORD

ID
Family
Acetylation
Complete proteome
Hydrogen ion transport
Ion transport
Membrane
Reference proteome
Transport
Vacuole

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Chloroplast
Cellular Component
Golgi apparatus
Cellular Component
Plant-type vacuole
Cellular Component
Plasma membrane
Cellular Component
Vacuolar membrane
Cellular Component
Vacuolar proton-transporting V-type ATPase, V1 domain
Cellular Component
Vacuole
Molecular Function
Proton-transporting ATPase activity, rotational mechanism
Biological Process
ATP hydrolysis coupled proton transport

▼ KEGG


▼ ANNOTATION

Disorder
IUPred2A
Physicochemical
Compute pI/MwAAindex
Localization
COMPARTMENTS

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Arl-1192Arabidopsis lyrata92.970.0 833
LLPS-Bro-0619Brassica oleracea92.040.0 853
LLPS-Brn-2205Brassica napus91.590.0 853
LLPS-Brr-1494Brassica rapa91.590.0 853
LLPS-Prp-1880Prunus persica80.970.0 751
LLPS-Thc-1117Theobroma cacao80.350.0 767
LLPS-Cus-1979Cucumis sativus79.650.0 751
LLPS-Sot-2212Solanum tuberosum78.940.0 741
LLPS-Gor-0443Gossypium raimondii78.790.0 756
LLPS-Mae-2404Manihot esculenta78.540.0 734
LLPS-Nia-2196Nicotiana attenuata78.050.0 733
LLPS-Glm-0787Glycine max77.830.0 729
LLPS-Pot-1875Populus trichocarpa77.380.0 711
LLPS-Hea-2509Helianthus annuus76.770.0 729
LLPS-Amt-1066Amborella trichopoda75.420.0 730
LLPS-Viv-2070Vitis vinifera74.950.0 739
LLPS-Sol-0068Solanum lycopersicum74.340.0 707
LLPS-Mua-0236Musa acuminata73.740.0 699
LLPS-Coc-0591Corchorus capsularis73.390.0 664
LLPS-Vir-0672Vigna radiata73.220.0 687
LLPS-Phv-0977Phaseolus vulgaris72.910.0 727
LLPS-Dac-0982Daucus carota72.520.0 719
LLPS-Met-0628Medicago truncatula72.160.0 713
LLPS-Hov-2003Hordeum vulgare71.720.0 680
LLPS-Tra-1524Triticum aestivum71.620.0 692
LLPS-Sei-0982Setaria italica71.40.0 684
LLPS-Orgl-1169Oryza glumaepatula71.020.0 684
LLPS-Orni-1626Oryza nivara71.020.0 684
LLPS-Ori-1329Oryza indica71.020.0 682
LLPS-Orb-0755Oryza barthii71.020.0 684
LLPS-Zem-0323Zea mays71.020.0 681
LLPS-Orr-0453Oryza rufipogon70.950.0 677
LLPS-Orbr-0721Oryza brachyantha70.350.0 668
LLPS-Orm-0851Oryza meridionalis70.296e-166 477
LLPS-Orp-1326Oryza punctata70.070.0 670
LLPS-Ors-0394Oryza sativa70.03e-46 162
LLPS-Org-2018Oryza glaberrima69.315e-41 147
LLPS-Tru-1465Triticum urartu68.10.0 634
LLPS-Via-1152Vigna angularis67.55e-126 374
LLPS-Sob-0279Sorghum bicolor67.290.0 675
LLPS-Lep-1790Leersia perrieri63.860.0 576
LLPS-Brd-1017Brachypodium distachyon61.250.0 626
LLPS-Sem-2370Selaginella moellendorffii60.360.0 561
LLPS-Php-1662Physcomitrella patens60.00.0 567
LLPS-Osl-0823Ostreococcus lucimarinus46.151e-25 105
LLPS-Chr-1383Chlamydomonas reinhardtii42.896e-124 375
LLPS-Chc-0943Chondrus crispus38.961e-45 170
LLPS-Lem-1311Leptosphaeria maculans35.683e-1581.6
LLPS-Crn-0860Cryptococcus neoformans33.649e-56 197
LLPS-Usm-0741Ustilago maydis32.875e-39 152
LLPS-Abg-0825Absidia glauca32.641e-59 207
LLPS-Gag-1273Gaeumannomyces graminis32.092e-23 105
LLPS-Drm-1610Drosophila melanogaster31.84e-41 158
LLPS-Spr-0039Sporisorium reilianum31.491e-35 142
LLPS-Beb-1074Beauveria bassiana31.461e-1273.6
LLPS-Fuv-0867Fusarium verticillioides31.132e-1994.7
LLPS-Trv-1425Trichoderma virens30.991e-1995.1
LLPS-Fus-1397Fusarium solani30.775e-1890.1
LLPS-Trr-1631Trichoderma reesei30.573e-2096.7
LLPS-Nec-1614Neurospora crassa30.053e-1891.3
LLPS-Asg-0601Ashbya gossypii30.042e-1994.7
LLPS-Miv-1201Microbotryum violaceum29.725e-60 208
LLPS-Scj-0603Schizosaccharomyces japonicus29.631e-42 161
LLPS-Ere-0955Erinaceus europaeus29.222e-56 197
LLPS-Ast-1095Aspergillus terreus29.229e-1786.7
LLPS-Pes-1791Pelodiscus sinensis28.898e-64 219
LLPS-Poa-3771Pongo abelii28.772e-65 223
LLPS-Aon-0914Aotus nancymaae28.679e-64 219
LLPS-Cym-0033Cyanidioschyzon merolae28.633e-31 128
LLPS-Cis-0372Ciona savignyi28.477e-62 214
LLPS-Anp-1899Anas platyrhynchos28.313e-64 220
LLPS-Mum-4988Mus musculus28.292e-63 218
LLPS-Cea-3953Cercocebus atys28.285e-54 193
LLPS-Pof-0017Poecilia formosa28.282e-63 219
LLPS-Man-4133Macaca nemestrina28.191e-63 219
LLPS-Scf-3159Scleropages formosus28.121e-63 219
LLPS-Gaga-3726Gallus gallus28.126e-64 220
LLPS-Fia-0131Ficedula albicollis28.122e-63 218
LLPS-Meg-0724Meleagris gallopavo28.121e-61 214
LLPS-Mal-3440Mandrillus leucophaeus28.063e-63 218
LLPS-Ran-0138Rattus norvegicus28.064e-63 218
LLPS-Caj-3322Callithrix jacchus28.062e-63 219
LLPS-Fud-3168Fukomys damarensis28.062e-63 218
LLPS-Gog-3815Gorilla gorilla28.061e-63 219
LLPS-Chs-3811Chlorocebus sabaeus28.063e-63 218
LLPS-Maf-4197Macaca fascicularis28.063e-63 218
LLPS-Mea-3482Mesocricetus auratus28.062e-62 216
LLPS-Nol-2313Nomascus leucogenys28.061e-63 219
LLPS-Cap-0958Cavia porcellus28.063e-63 218
LLPS-Rhb-0596Rhinopithecus bieti28.063e-63 218
LLPS-Orc-2100Oryctolagus cuniculus28.063e-63 218
LLPS-Hos-3632Homo sapiens28.061e-63 219
LLPS-Pat-0663Pan troglodytes28.061e-63 219
LLPS-Pap-1010Pan paniscus28.061e-63 219
LLPS-Xim-1173Xiphophorus maculatus28.054e-63 218
LLPS-Paa-3566Papio anubis28.044e-63 218
LLPS-Tut-1265Tursiops truncatus28.04e-62 215
LLPS-Cii-1438Ciona intestinalis27.931e-58 205
LLPS-Mel-0908Melampsora laricipopulina27.95e-48 176
LLPS-Mup-2080Mustela putorius furo27.842e-63 218
LLPS-Ict-4507Ictidomys tridecemlineatus27.842e-62 216
LLPS-Eqc-2045Equus caballus27.842e-63 218
LLPS-Fec-2023Felis catus27.847e-63 217
LLPS-Urm-3652Ursus maritimus27.842e-63 218
LLPS-Mod-3682Monodelphis domestica27.818e-60 209
LLPS-Lac-2690Latimeria chalumnae27.772e-64 221
LLPS-Sah-2263Sarcophilus harrisii27.746e-62 214
LLPS-Ten-2895Tetraodon nigroviridis27.744e-63 218
LLPS-Otg-3201Otolemur garnettii27.692e-62 216
LLPS-Tag-2875Taeniopygia guttata27.673e-54 194
LLPS-Leo-2710Lepisosteus oculatus27.665e-63 217
LLPS-Cog-1162Colletotrichum gloeosporioides27.651e-24 109
LLPS-Dio-1512Dipodomys ordii27.623e-62 215
LLPS-Loa-0263Loxodonta africana27.624e-62 215
LLPS-Scm-3560Scophthalmus maximus27.61e-61 214
LLPS-Anc-3035Anolis carolinensis27.585e-61 212
LLPS-Mam-4272Macaca mulatta27.561e-62 217
LLPS-Ora-1382Ornithorhynchus anatinus27.522e-63 219
LLPS-Coo-1273Colletotrichum orbiculare27.513e-25 111
LLPS-Orl-1142Oryzias latipes27.56e-63 217
LLPS-Gaa-2615Gasterosteus aculeatus27.466e-62 214
LLPS-Cas-2782Carlito syrichta27.425e-57 201
LLPS-Ova-0301Ovis aries27.393e-61 213
LLPS-Caf-2219Canis familiaris27.391e-61 214
LLPS-Tar-0202Takifugu rubripes27.383e-61 213
LLPS-Icp-3618Ictalurus punctatus27.351e-61 213
LLPS-Dar-1046Danio rerio27.352e-61 213
LLPS-Xet-1466Xenopus tropicalis27.335e-65 223
LLPS-Myl-4238Myotis lucifugus27.291e-61 214
LLPS-Orn-3418Oreochromis niloticus27.233e-61 213
LLPS-Cae-0603Caenorhabditis elegans27.177e-48 176
LLPS-Sus-4499Sus scrofa27.172e-61 213
LLPS-Asm-2673Astyanax mexicanus27.136e-61 212
LLPS-Bot-3827Bos taurus26.852e-60 210
LLPS-Aim-2148Ailuropoda melanoleuca26.849e-44 163
LLPS-Fuo-1424Fusarium oxysporum26.681e-1995.5
LLPS-Ved-1398Verticillium dahliae26.594e-2199.8
LLPS-Pug-0279Puccinia graminis26.546e-48 176
LLPS-Dos-1381Dothistroma septosporum26.461e-24 109
LLPS-Scp-0419Schizosaccharomyces pombe26.43e-35 140
LLPS-Asc-0404Aspergillus clavatus26.41e-24 109
LLPS-Cogr-0702Colletotrichum graminicola26.28e-22 101
LLPS-Yal-0642Yarrowia lipolytica26.074e-39 151
LLPS-Asfu-1578Aspergillus fumigatus25.991e-23 106
LLPS-Sac-1199Saccharomyces cerevisiae25.944e-1581.6
LLPS-Pyt-1650Pyrenophora teres25.861e-1995.1
LLPS-Map-0715Magnaporthe poae25.763e-24 108
LLPS-Zyt-1261Zymoseptoria tritici25.714e-2096.3
LLPS-Pytr-1553Pyrenophora triticirepentis25.654e-2199.4
LLPS-Put-1201Puccinia triticina25.589e-34 137
LLPS-Nef-0697Neosartorya fischeri25.334e-23 105
LLPS-Mao-1519Magnaporthe oryzae25.115e-2199.4
LLPS-Phn-0075Phaeosphaeria nodorum25.116e-22 102
LLPS-Asni-1252Aspergillus niger25.08e-2198.6
LLPS-Asf-1599Aspergillus flavus24.784e-1993.6
LLPS-Aso-1295Aspergillus oryzae24.784e-1993.6
LLPS-Scc-0660Schizosaccharomyces cryophilus24.414e-34 137
LLPS-Blg-0663Blumeria graminis24.393e-1890.9
LLPS-Gas-0473Galdieria sulphuraria24.341e-35 142
LLPS-Asn-0707Aspergillus nidulans24.283e-2199.8
LLPS-Tum-0593Tuber melanosporum23.136e-2199.0
LLPS-Kop-1492Komagataella pastoris23.134e-23 105