Otolemur garnettii      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 38 genes.  Reviewed (0 or Unreviewed (38

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Otg-0532
ENSOGAG00000030012.1
H0XK00
2
LLPS-Otg-0917
ENSOGAG00000015192.2
H0XCS1
3
LLPS-Otg-2593
ENSOGAG00000015386.2
H0XD55
4
LLPS-Otg-3264
ENSOGAG00000009849.2
H0X1E3
5
LLPS-Otg-2299
ENSOGAG00000008542.2
H0WYP9
CDC6
6
LLPS-Otg-2918
ENSOGAG00000008428.2
H0WYG6
CKAP2
7
LLPS-Otg-0616
ENSOGAG00000004560.2
H0WQ65
CKAP5
8
LLPS-Otg-4156
ENSOGAG00000031559.1
H0XVY5
CLTB
9
LLPS-Otg-0084
ENSOGAG00000008248.2
H0WY21
DCTN3
10
LLPS-Otg-3272
ENSOGAG00000027526.1
H0XLH7
DLGAP5
11
LLPS-Otg-1320
ENSOGAG00000011250.2
H0X4F2
DPYSL2
12
LLPS-Otg-4445
ENSOGAG00000025150.1
H0XYC0
DYRK3
13
LLPS-Otg-0259
ENSOGAG00000005721.2
H0WSP6
FES
14
LLPS-Otg-4511
ENSOGAG00000013470.2
H0X961
GPSM2
15
LLPS-Otg-3554
ENSOGAG00000032569.1
H0Y0G8
HAUS3
16
LLPS-Otg-0492
ENSOGAG00000001915.2
H0WJM5
KAT14
17
LLPS-Otg-4542
ENSOGAG00000011308.2
H0X4J5
KATNAL1
18
LLPS-Otg-1295
ENSOGAG00000004054.2
H0XIZ7
LOC100957931
19
LLPS-Otg-2260
ENSOGAG00000009716.2
H0X145
MAD2L2
20
LLPS-Otg-4118
ENSOGAG00000030786.1
H0XVF9
MAPK6
21
LLPS-Otg-1874
ENSOGAG00000026557.1
H0XPX6
MAPRE1
22
LLPS-Otg-0747
ENSOGAG00000024985.1
H0XTA6
MARVELD1
23
LLPS-Otg-0709
ENSOGAG00000014430.2
H0XB76
MKNK1
24
LLPS-Otg-2637
ENSOGAG00000007159.2
H0WVR4
MSN
25
LLPS-Otg-1313
ENSOGAG00000013669.2
H0X9K8
MTOR
26
LLPS-Otg-2828
ENSOGAG00000004229.2
H0WPG9
MTUS1
27
LLPS-Otg-1080
ENSOGAG00000004069.2
H0WP35
PARD3
28
LLPS-Otg-3774
ENSOGAG00000015555.2
H0XDI3
RANBP10
29
LLPS-Otg-1702
ENSOGAG00000030298.1
H0Y1Z9
RBPMS
30
LLPS-Otg-1541
ENSOGAG00000004457.2
H0XNL6
SEPT2
31
LLPS-Otg-0438
ENSOGAG00000003155.2
H0WM80
SMC3
32
LLPS-Otg-0573
ENSOGAG00000011509.2
H0X4Z0
SUN1
33
LLPS-Otg-0354
ENSOGAG00000000515.2
H0WGK7
SUN2
34
LLPS-Otg-2779
ENSOGAG00000034225.1
H0XTK0
TADA3
35
LLPS-Otg-3384
ENSOGAG00000007107.2
H0WVL8
TMEM201
36
LLPS-Otg-1595
ENSOGAG00000001609.2
H0WIZ7
TPR
37
LLPS-Otg-1535
ENSOGAG00000034491.1
H0XLI8
ZBTB4
38
LLPS-Otg-1287
ENSOGAG00000001200.2
H0WI39
ZNF207