LLPS-Otg-0259
FES
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Tyrosine-protein kinase |
| Gene Name: | FES |
| Ensembl Gene: | ENSOGAG00000005721.2 |
| Ensembl Protein: | ENSOGAP00000005114.2 |
| Organism: | Otolemur garnettii |
| Taxa ID: | 30611 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Spindle apparatus | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSOGAT00000005724.2 | ENSOGAP00000005114.2 |
| UniProt | H0WSP6, H0WSP6_OTOGA | |
| GeneBank | AAQR03183213, AAQR03183212 | |
| RefSeq | XM_003803079.2 | XP_003803127.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MGFSSELCST QGHGALQQMQ EAELRLLEGM RKWMAQRVKS DREYAGLLHH MSLQDGGGQS 60 61 RGISPDSPIS QSWAEITSQT EGLSKVLRQH AEDLHTGPLS RLSLLIRERQ QLRKTYSEQW 120 121 QQLQQDLTKI HSHDIEKLKS QYRTLARDSA QARRKYQEAS KDKDRDKAKD KYVRSLWKLF 180 181 AHHNRYVLGV RAAQLHHQHH HQLLLPGLLC SLQELHEEMA SILKEILQEY LEMSSLVQDE 240 241 VVAIHREMAA AAARIQPQAE YQGFLRQYGS APDIPPCVTF DDSLLEEGEP LEPGELQLNE 300 301 LTVESVQHTL TSVTDELSVA SELVLSRQEV VTQLQCELQS EEQNTHSRER VQLLGKRQAL 360 361 LEALQGLQVA LCSQAKLQAQ RELLQTKLGQ LGPGEPPPVL LLQDDRHSTS SSEPEREGGR 420 421 TPTLEILKSH ISGIFRPKFS LPPPLQLVPE VQKPLHEQLW YHGAIPRTEV AELLRHSGDF 480 481 LVRESQGKQE HVLSVLWDGL PRHFIIQASD NLYRLEGDGF PSIPLLIDDL LSSQQPVTKK 540 541 SGIILHRAVP RDKWALSHED LVLGEQIGRG NFGEVFSGRL RADNTLVAVK SCRETLPPDL 600 601 KAKFLQEARI LKQYNHPNIV RLIGVCTQKQ PIYIVMELVQ GGDFLTFLRT EGARLRVKTL 660 661 LRMVGDAASG MEYLESKCCI HRDLAARNCL VTEKNVLKIS DFGMSREEAD GIYAASGGLR 720 721 QVPVKWTAPE ALNYGRYSSE SDVWSFGILL WETFSLGASP YPNLSNQQTR EFVEKGGRLP 780 781 CPELCPDAVF RLMEQCWAYE PGQRPSFSNI CQELHNIRKR HR 822 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGGCTTCT CTTCGGAGCT CTGCAGCACT CAGGGCCATG GGGCCCTGCA GCAGATGCAG 60 61 GAGGCTGAGC TTCGCCTGCT GGAGGGCATG AGGAAGTGGA TGGCCCAACG AGTCAAGAGT 120 121 GACAGGGAGT ACGCAGGACT GCTTCATCAC ATGTCCCTGC AGGACGGTGG GGGCCAGAGT 180 181 CGGGGCATTA GCCCTGATAG CCCTATCAGC CAGTCCTGGG CCGAGATCAC CAGCCAAACA 240 241 GAGGGCTTGA GCAAGGTGCT GCGGCAGCAT GCAGAGGACC TGCACACAGG GCCCCTGAGC 300 301 AGGCTGAGCC TGCTGATCCG TGAGCGCCAG CAGCTGCGCA AGACCTACAG CGAGCAGTGG 360 361 CAGCAGCTGC AGCAGGATCT TACCAAGATC CACAGCCATG ACATCGAGAA GCTGAAGAGC 420 421 CAGTACCGAA CTCTAGCACG GGACAGTGCT CAAGCTAGGC GCAAGTACCA GGAGGCCAGC 480 481 AAAGACAAGG ACCGTGACAA GGCTAAGGAC AAGTATGTGC GCAGCCTATG GAAGCTCTTT 540 541 GCCCACCACA ACCGCTACGT GCTGGGGGTG CGGGCCGCAC AGCTGCACCA CCAGCACCAC 600 601 CACCAGCTGC TGCTGCCTGG CCTGCTATGC TCACTGCAGG AGCTGCATGA GGAGATGGCA 660 661 AGCATCCTGA AGGAGATCCT GCAGGAATAC CTGGAGATGA GCAGTCTGGT ACAGGACGAG 720 721 GTAGTGGCCA TTCACAGAGA GATGGCTGCA GCTGCTGCCC GCATCCAGCC CCAGGCCGAG 780 781 TACCAAGGCT TCCTGAGACA GTATGGGTCT GCACCTGACA TCCCACCCTG CGTCACCTTT 840 841 GATGATTCAC TGCTTGAGGA AGGAGAACCA CTGGAGCCTG GGGAGCTGCA GCTGAACGAG 900 901 CTCACTGTGG AGAGTGTGCA GCACACGCTG ACCTCAGTGA CAGATGAACT ATCTGTGGCC 960 961 TCAGAGTTGG TCCTCAGCCG ACAGGAGGTG GTCACTCAGC TGCAGTGTGA GCTTCAGAGC 1020 1021 GAAGAACAGA ACACCCACTC CCGGGAGCGG GTGCAGCTTC TGGGCAAGCG GCAAGCACTG 1080 1081 CTGGAGGCCC TGCAGGGACT GCAGGTGGCG CTGTGCAGCC AGGCCAAGCT GCAGGCCCAG 1140 1141 CGGGAGCTGC TGCAGACCAA GCTGGGGCAG CTGGGCCCTG GTGAGCCCCC ACCCGTGCTG 1200 1201 CTTCTGCAGG ATGACCGCCA CTCCACATCA TCATCGGAGC CGGAGCGAGA GGGGGGAAGG 1260 1261 ACACCCACTC TGGAGATCCT TAAGAGCCAC ATCTCTGGAA TCTTCCGCCC CAAGTTCTCG 1320 1321 CTCCCCCCAC CCCTGCAGCT TGTTCCTGAA GTGCAGAAGC CCCTACACGA GCAGCTGTGG 1380 1381 TACCATGGGG CTATCCCACG GACAGAGGTG GCGGAGCTAC TGCGGCACTC TGGGGACTTT 1440 1441 CTGGTGCGGG AGAGCCAGGG CAAGCAGGAG CATGTGCTGT CGGTGCTGTG GGACGGCCTG 1500 1501 CCGCGGCACT TCATCATCCA GGCCTCAGAC AATCTGTACC GGCTAGAAGG GGACGGCTTT 1560 1561 CCCAGCATCC CATTGCTCAT CGACGACCTG CTGTCTTCCC AGCAGCCCGT CACCAAGAAG 1620 1621 AGTGGCATCA TCCTACACAG AGCCGTGCCC CGGGACAAAT GGGCACTGAG CCATGAGGAC 1680 1681 CTGGTGCTGG GCGAGCAGAT CGGACGGGGA AACTTTGGAG AGGTGTTCAG TGGACGCCTG 1740 1741 CGAGCAGACA ATACCCTAGT GGCAGTGAAG TCTTGTCGAG AGACGCTTCC ACCTGACCTC 1800 1801 AAGGCCAAGT TTCTACAGGA AGCAAGGATC CTGAAGCAGT ACAATCACCC CAACATTGTG 1860 1861 CGCCTCATCG GTGTCTGCAC CCAGAAGCAG CCCATTTATA TCGTCATGGA GCTGGTGCAG 1920 1921 GGGGGGGACT TTCTCACCTT CCTGCGGACA GAGGGCGCCC GCCTGCGGGT GAAGACCCTG 1980 1981 CTGCGGATGG TGGGGGATGC AGCCTCTGGC ATGGAATACC TGGAGAGCAA GTGCTGCATC 2040 2041 CACCGGGACC TGGCTGCTCG GAACTGCCTG GTGACAGAGA AGAATGTCCT GAAAATCAGT 2100 2101 GACTTTGGGA TGTCCCGGGA GGAAGCTGAT GGGATCTATG CAGCCTCAGG GGGTCTCAGA 2160 2161 CAAGTCCCCG TGAAGTGGAC TGCGCCTGAG GCTCTTAACT ACGGCCGTTA TTCCTCTGAG 2220 2221 AGTGATGTAT GGAGCTTTGG CATCTTGCTC TGGGAGACCT TCAGCCTGGG GGCCTCCCCC 2280 2281 TACCCCAACC TCAGCAATCA GCAGACTCGG GAATTTGTAG AAAAGGGGGG CCGCCTGCCC 2340 2341 TGCCCAGAGC TGTGCCCCGA TGCTGTGTTC AGGCTCATGG AGCAATGCTG GGCCTATGAG 2400 2401 CCTGGGCAGC GGCCGAGCTT CAGCAACATC TGCCAGGAGC TGCACAACAT CCGGAAGAGG 2460 2461 CATCGGTGA 2469 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-2208 | Homo sapiens | 92.58 | 0.0 | 1324 |
| LLPS-Cea-2504 | Cercocebus atys | 92.53 | 0.0 | 1228 |
| LLPS-Mam-3376 | Macaca mulatta | 92.46 | 0.0 | 1320 |
| LLPS-Poa-2664 | Pongo abelii | 92.46 | 0.0 | 1317 |
| LLPS-Caj-2930 | Callithrix jacchus | 92.46 | 0.0 | 1315 |
| LLPS-Chs-2923 | Chlorocebus sabaeus | 92.34 | 0.0 | 1316 |
| LLPS-Cas-1285 | Carlito syrichta | 92.21 | 0.0 | 1313 |
| LLPS-Rhb-3580 | Rhinopithecus bieti | 92.09 | 0.0 | 1313 |
| LLPS-Aim-4049 | Ailuropoda melanoleuca | 91.73 | 0.0 | 1291 |
| LLPS-Ict-2730 | Ictidomys tridecemlineatus | 91.48 | 0.0 | 1308 |
| LLPS-Gog-2380 | Gorilla gorilla | 91.17 | 0.0 | 1316 |
| LLPS-Caf-0878 | Canis familiaris | 91.12 | 0.0 | 1295 |
| LLPS-Pat-2702 | Pan troglodytes | 91.05 | 0.0 | 1317 |
| LLPS-Pap-3033 | Pan paniscus | 91.05 | 0.0 | 1317 |
| LLPS-Mup-0431 | Mustela putorius furo | 91.0 | 0.0 | 1314 |
| LLPS-Maf-2205 | Macaca fascicularis | 90.81 | 0.0 | 1314 |
| LLPS-Bot-4168 | Bos taurus | 90.75 | 0.0 | 1316 |
| LLPS-Fud-1153 | Fukomys damarensis | 90.75 | 0.0 | 1292 |
| LLPS-Sus-2091 | Sus scrofa | 90.75 | 0.0 | 1307 |
| LLPS-Man-1310 | Macaca nemestrina | 90.69 | 0.0 | 1310 |
| LLPS-Mal-0149 | Mandrillus leucophaeus | 90.69 | 0.0 | 1308 |
| LLPS-Eqc-2310 | Equus caballus | 90.42 | 0.0 | 1129 |
| LLPS-Urm-2427 | Ursus maritimus | 90.29 | 1e-130 | 416 |
| LLPS-Tut-2448 | Tursiops truncatus | 89.9 | 0.0 | 1252 |
| LLPS-Nol-4116 | Nomascus leucogenys | 89.86 | 0.0 | 1293 |
| LLPS-Loa-2631 | Loxodonta africana | 89.66 | 0.0 | 1282 |
| LLPS-Fec-0711 | Felis catus | 89.54 | 0.0 | 1286 |
| LLPS-Paa-2287 | Papio anubis | 89.24 | 0.0 | 1275 |
| LLPS-Aon-3360 | Aotus nancymaae | 89.17 | 0.0 | 1268 |
| LLPS-Ran-0324 | Rattus norvegicus | 89.05 | 0.0 | 1281 |
| LLPS-Mum-2657 | Mus musculus | 88.69 | 0.0 | 1281 |
| LLPS-Mea-0697 | Mesocricetus auratus | 88.08 | 0.0 | 1269 |
| LLPS-Ova-1104 | Ovis aries | 85.56 | 0.0 | 1244 |
| LLPS-Mod-1015 | Monodelphis domestica | 85.28 | 0.0 | 1231 |
| LLPS-Ora-1595 | Ornithorhynchus anatinus | 83.64 | 5e-110 | 341 |
| LLPS-Gaga-0638 | Gallus gallus | 68.32 | 0.0 | 914 |
| LLPS-Meg-2733 | Meleagris gallopavo | 66.4 | 0.0 | 834 |
| LLPS-Tag-1646 | Taeniopygia guttata | 63.26 | 0.0 | 892 |
| LLPS-Xet-1931 | Xenopus tropicalis | 62.59 | 0.0 | 931 |
| LLPS-Lac-2988 | Latimeria chalumnae | 59.76 | 0.0 | 855 |
| LLPS-Leo-2475 | Lepisosteus oculatus | 59.69 | 0.0 | 861 |
| LLPS-Dar-3443 | Danio rerio | 57.18 | 0.0 | 838 |
| LLPS-Scf-3611 | Scleropages formosus | 57.16 | 0.0 | 842 |
| LLPS-Icp-1539 | Ictalurus punctatus | 56.99 | 0.0 | 828 |
| LLPS-Asm-0890 | Astyanax mexicanus | 56.32 | 0.0 | 831 |
| LLPS-Orn-0391 | Oreochromis niloticus | 54.81 | 0.0 | 761 |
| LLPS-Scm-2373 | Scophthalmus maximus | 54.7 | 0.0 | 762 |
| LLPS-Gaa-0556 | Gasterosteus aculeatus | 54.47 | 0.0 | 740 |
| LLPS-Xim-0520 | Xiphophorus maculatus | 53.99 | 0.0 | 701 |
| LLPS-Orl-3698 | Oryzias latipes | 53.71 | 0.0 | 742 |
| LLPS-Pof-2804 | Poecilia formosa | 53.69 | 0.0 | 750 |
| LLPS-Cii-1598 | Ciona intestinalis | 51.82 | 1e-122 | 396 |
| LLPS-Ten-1073 | Tetraodon nigroviridis | 51.64 | 0.0 | 715 |
| LLPS-Tar-2183 | Takifugu rubripes | 50.78 | 0.0 | 729 |
| LLPS-Pes-3590 | Pelodiscus sinensis | 50.36 | 0.0 | 711 |
| LLPS-Cap-1978 | Cavia porcellus | 49.46 | 0.0 | 700 |
| LLPS-Anc-2144 | Anolis carolinensis | 48.88 | 0.0 | 700 |
| LLPS-Anp-1782 | Anas platyrhynchos | 46.81 | 0.0 | 648 |
| LLPS-Dio-4132 | Dipodomys ordii | 46.67 | 0.0 | 625 |
| LLPS-Orc-2554 | Oryctolagus cuniculus | 45.73 | 4e-163 | 499 |
| LLPS-Drm-1667 | Drosophila melanogaster | 45.42 | 6e-63 | 236 |
| LLPS-Myl-3458 | Myotis lucifugus | 40.75 | 3e-87 | 294 |
| LLPS-Cis-0445 | Ciona savignyi | 37.7 | 5e-67 | 236 |
| LLPS-Cae-1791 | Caenorhabditis elegans | 36.99 | 6e-67 | 233 |