Ciona intestinalis      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 18 genes.  Reviewed (0 or Unreviewed (18

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cii-0147
ENSCING00000007598.4
F6ZJZ6
2
LLPS-Cii-0222
ENSCING00000003687.4
F6WUJ1
3
LLPS-Cii-0242
ENSCING00000008216.3
F6RU68
4
LLPS-Cii-0358
ENSCING00000008866.3
F6QYJ8
5
LLPS-Cii-0449
ENSCING00000006319.3
F6Q476
6
LLPS-Cii-0489
ENSCING00000021754.1
H2XRK6
7
LLPS-Cii-0681
ENSCING00000002198.3
F6S4S1
8
LLPS-Cii-0720
ENSCING00000001460.3
F6VK85
9
LLPS-Cii-1770
ENSCING00000002444.3
F6QNQ9
10
LLPS-Cii-1809
ENSCING00000008712.3
F6WCC6
11
LLPS-Cii-1842
ENSCING00000023397.1
H2XTY4
12
LLPS-Cii-2018
ENSCING00000003978.3
F6Z0L2
13
LLPS-Cii-2101
ENSCING00000020218.1
F6SA56
14
LLPS-Cii-1646
ENSCING00000006246.3
Q4H2I7
Ci-ZF(C2H2)-28
15
LLPS-Cii-2207
ENSCING00000009222.3
F6W1Z3
LOC100177191
16
LLPS-Cii-1520
ENSCING00000001669.3
F6X8B5
LOC100182084
17
LLPS-Cii-1803
ENSCING00000009076.3
F6QEV0
LOC100184538
18
LLPS-Cii-1446
ENSCING00000005193.2
F7B7C2
LOC100186196