Loxodonta africana      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Loa-0692
ENSLAFG00000029587.1
G3TVP3
2
LLPS-Loa-3573
ENSLAFG00000003425.3
G3SSC9
3
LLPS-Loa-3835
ENSLAFG00000016483.1
G3TH39
HNRNPD
4
LLPS-Loa-1135
ENSLAFG00000026567.1
G3U2B1
HNRNPK
5
LLPS-Loa-4432
ENSLAFG00000025536.1
G3U4N4
HNRNPL
6
LLPS-Loa-1321
ENSLAFG00000006655.3
G3SYK3
KHDRBS2
7
LLPS-Loa-0568
ENSLAFG00000026404.1
G3TT56
MAK16
8
LLPS-Loa-0293
ENSLAFG00000013953.3
G5E771
NGDN
9
LLPS-Loa-4293
ENSLAFG00000005568.2
G3SWH5
RBMX
10
LLPS-Loa-4345
ENSLAFG00000010190.4
G3T554
TLE3
11
LLPS-Loa-0260
ENSLAFG00000021592.2
G3TQR4
YTHDC1