• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Loa-4345
TLE3

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Transducin like enhancer of split 3
Gene Name: TLE3
Ensembl Gene: ENSLAFG00000010190.4
Ensembl Protein: ENSLAFP00000008541.4
Organism: Loxodonta africana
Taxa ID: 9785
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Sam68 nuclear bodyPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MYPQGRHPAP  HQPGQPGFKF  TVAESCDRIK  DEFQFLQAQY  HSLKVEYDKL  ANEKTEMQRH  60
61    YVMYYEMSYG  LNIEMHKQTE  IAKRLNTILA  QIMPFLSQEH  QQQVAQAVER  AKQVTMTELN  120
121   AIIGQQQLQA  QHLSHATHGP  PVQLPPHPSG  LQPPGIPPVT  GSSSGLLALG  ALGSQAHLTV  180
181   KDEKNHHELD  HRGTAQGWNN  SVSPSESLRA  SEKHRASTDY  SLEAKKRKAE  EKDSLSRYDS  240
241   DGDKSDDLVV  DVSNEDPATP  RVSPAHSPPE  NGLDKARGLK  KDAPTSPASV  ASSSSTPSSK  300
301   TKDLGHNDKS  STPGLKSNTP  TPRNDAPTPG  TSTTPGLRSM  PGKHPGMDPL  GIMASALRTP  360
361   ISITSSYAAP  FAMMSHHEMN  GSLTSPGAYA  SLHNIPPQMS  AAAAAAAAAY  GRSPMVSFGA  420
421   VGFEPHPPMR  ATGLPSSLAS  IPGGKPAYSF  HVSADGQMQP  VPFPHDALAG  PGIPRHARQI  480
481   NTLSHGEVVC  AVTISNPTRH  VYTGGKGCVK  IWDMSQPGGK  SPVSQLDCLN  RDNYIRSCKL  540
541   LPDGRTLIVG  GEASTLTIWD  LASPTPRIKA  ELTSSAPACY  ALAISPDAKV  CFSCCSDGNI  600
601   AVWDLHNQTL  VRQFQGHTDG  ASCIDISHDG  TKLWTGGLDN  TVRSWDLREG  RQLQQHDFTS  660
661   QIFSLGYCPT  GEWLAVGMES  SNVEVLHHTK  PDKYQLHLHE  SCVLSLKFAY  CGKWFVSTGK  720
721   DNLLNAWRTP  YGASIFQSKE  SSSVLSCDIS  ADDKYIVTGS  GDKKATVYEV  IY  772
Nucleotide CDS Sequence (FASTA)
1     ATGTATCCGC  AAGGCAGACA  TCCGGCTCCC  CATCAACCTG  GGCAGCCAGG  ATTTAAATTC  60
61    ACGGTGGCTG  AGTCTTGTGA  CAGGATCAAA  GACGAATTCC  AGTTTCTGCA  AGCTCAATAT  120
121   CACAGCCTTA  AAGTGGAGTA  CGACAAGCTG  GCGAACGAGA  AGACCGAGAT  GCAGCGCCAT  180
181   TATGTGATGT  ACTACGAGAT  GTCCTATGGC  TTGAACATTG  AAATGCACAA  GCAGACAGAG  240
241   ATCGCGAAGA  GACTGAACAC  AATTTTAGCG  CAGATCATGC  CTTTCCTGTC  ACAAGAGCAC  300
301   CAGCAGCAGG  TGGCACAGGC  GGTGGAGCGT  GCCAAGCAGG  TCACCATGAC  GGAGCTGAAC  360
361   GCCATCATCG  GGCAGCAGCA  GCTCCAGGCG  CAGCATCTCT  CCCATGCCAC  ACATGGGCCC  420
421   CCGGTCCAGC  TACCACCCCA  CCCATCAGGC  CTCCAGCCTC  CAGGGATACC  CCCAGTGACG  480
481   GGGAGCAGCT  CAGGGCTGCT  GGCGCTTGGT  GCCCTGGGCA  GCCAGGCCCA  CCTGACAGTG  540
541   AAGGATGAGA  AGAACCACCA  TGAACTTGAC  CACAGAGGTA  CGGCCCAGGG  CTGGAATAAC  600
601   TCGGTGTCAC  CCTCGGAAAG  CCTCCGGGCC  AGTGAAAAGC  ACCGGGCCTC  CACAGACTAT  660
661   AGCCTGGAAG  CCAAGAAGCG  GAAAGCAGAG  GAGAAGGACA  GCCTGAGCCG  ATACGACAGT  720
721   GACGGGGACA  AGAGTGACGA  TCTGGTGGTG  GACGTTTCCA  ATGAGGACCC  AGCGACGCCC  780
781   CGGGTGAGCC  CGGCACACTC  CCCTCCTGAA  AATGGGCTGG  ATAAGGCCCG  TGGCCTGAAA  840
841   AAGGATGCCC  CCACCAGCCC  CGCTTCGGTG  GCCTCTTCCA  GCAGCACACC  TTCCTCCAAG  900
901   ACCAAAGACC  TTGGTCATAA  TGACAAATCC  TCCACCCCCG  GGCTCAAGTC  CAACACGCCA  960
961   ACTCCAAGAA  ACGATGCTCC  GACTCCAGGC  ACCAGCACGA  CCCCGGGGCT  CCGGTCAATG  1020
1021  CCAGGCAAAC  ATCCTGGCAT  GGACCCTCTA  GGTATAATGG  CCTCTGCCCT  GCGCACGCCC  1080
1081  ATCTCCATCA  CCAGCTCCTA  TGCGGCGCCC  TTTGCCATGA  TGAGCCACCA  CGAGATGAAT  1140
1141  GGCTCGCTCA  CCAGCCCTGG  TGCCTACGCC  AGTCTCCACA  ACATCCCCCC  ACAGATGAGC  1200
1201  GCTGCCGCCG  CTGCCGCAGC  TGCCGCCTAT  GGCCGATCGC  CAATGGTGAG  CTTTGGAGCT  1260
1261  GTTGGTTTTG  AACCTCACCC  TCCCATGAGG  GCCACGGGCC  TGCCCTCAAG  CCTTGCCTCC  1320
1321  ATTCCTGGTG  GAAAACCAGC  GTACTCTTTC  CACGTGAGCG  CCGATGGGCA  GATGCAACCT  1380
1381  GTGCCCTTCC  CGCACGACGC  CCTGGCAGGC  CCTGGCATCC  CAAGGCACGC  CCGCCAAATC  1440
1441  AACACCCTGA  GCCATGGGGA  GGTGGTGTGC  GCCGTGACCA  TCAGCAACCC  CACGCGGCAC  1500
1501  GTCTACACGG  GCGGCAAGGG  CTGCGTGAAG  ATCTGGGACA  TGAGCCAGCC  AGGCGGCAAG  1560
1561  AGCCCCGTCT  CCCAGCTGGA  CTGCCTGAAC  AGGGACAACT  ACATCCGCTC  CTGCAAGCTG  1620
1621  CTCCCTGACG  GGCGCACACT  GATCGTGGGC  GGTGAGGCCA  GCACGCTCAC  CATCTGGGAC  1680
1681  CTGGCCTCAC  CCACGCCCCG  CATCAAAGCT  GAGCTGACGT  CCTCGGCTCC  TGCCTGCTAC  1740
1741  GCCCTGGCCA  TCAGCCCCGA  CGCCAAGGTC  TGCTTCTCCT  GCTGCAGCGA  TGGGAACATT  1800
1801  GCTGTCTGGG  ACCTGCACAA  CCAGACCCTG  GTCAGGCAGT  TCCAGGGCCA  CACAGACGGG  1860
1861  GCCAGCTGCA  TAGACATCTC  CCATGACGGC  ACTAAGCTGT  GGACAGGGGG  CCTGGACAAC  1920
1921  ACTGTGCGCT  CCTGGGACCT  GCGCGAGGGC  CGGCAGCTGC  AGCAACATGA  CTTCACCTCC  1980
1981  CAGATCTTCT  CTCTGGGGTA  CTGCCCCACT  GGGGAGTGGC  TGGCCGTGGG  CATGGAGAGC  2040
2041  AGCAACGTGG  AGGTACTGCA  TCACACCAAG  CCCGACAAGT  ACCAGCTGCA  CCTGCATGAG  2100
2101  AGCTGCGTGC  TCTCCCTCAA  GTTTGCCTAT  TGTGGCAAGT  GGTTTGTGAG  CACTGGGAAA  2160
2161  GACAACCTCC  TCAACGCCTG  GAGGACACCT  TATGGAGCCA  GCATATTCCA  GTCTAAAGAA  2220
2221  TCCTCGTCTG  TCTTGAGTTG  TGACATTTCG  GCGGATGACA  AATATATTGT  AACAGGCTCT  2280
2281  GGTGACAAGA  AGGCCACAGT  TTATGAGGTC  ATCTAC  2316

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Tut-2285Tursiops truncatus97.80.01400
LLPS-Cas-3566Carlito syrichta97.640.01383
LLPS-Mup-3709Mustela putorius furo97.540.01395
LLPS-Chs-2604Chlorocebus sabaeus97.540.01395
LLPS-Bot-1284Bos taurus97.410.01392
LLPS-Poa-1902Pongo abelii97.410.01393
LLPS-Ict-4087Ictidomys tridecemlineatus97.40.01389
LLPS-Orc-0168Oryctolagus cuniculus97.140.01380
LLPS-Caj-4719Callithrix jacchus97.010.01376
LLPS-Fec-3873Felis catus97.010.01320
LLPS-Aim-2552Ailuropoda melanoleuca96.760.01373
LLPS-Fud-3833Fukomys damarensis96.760.01384
LLPS-Cap-3386Cavia porcellus96.760.01388
LLPS-Mal-3077Mandrillus leucophaeus96.680.01398
LLPS-Mam-1844Macaca mulatta96.680.01392
LLPS-Maf-3147Macaca fascicularis96.550.01394
LLPS-Gog-3477Gorilla gorilla96.550.01396
LLPS-Hos-1918Homo sapiens96.550.01396
LLPS-Pat-2799Pan troglodytes96.550.01396
LLPS-Myl-2016Myotis lucifugus96.50.01368
LLPS-Nol-1731Nomascus leucogenys96.420.01394
LLPS-Ran-2883Rattus norvegicus96.370.01372
LLPS-Mea-4381Mesocricetus auratus96.160.01392
LLPS-Eqc-4596Equus caballus96.060.01075
LLPS-Mum-4680Mus musculus95.910.01385
LLPS-Otg-0258Otolemur garnettii95.380.01359
LLPS-Ova-2343Ovis aries95.210.01351
LLPS-Paa-0748Papio anubis94.90.01346
LLPS-Cea-2446Cercocebus atys94.90.01346
LLPS-Rhb-1982Rhinopithecus bieti94.90.01346
LLPS-Man-2349Macaca nemestrina94.770.01342
LLPS-Dio-4126Dipodomys ordii94.760.01373
LLPS-Gaga-1249Gallus gallus94.380.01354
LLPS-Sah-2469Sarcophilus harrisii94.120.01344
LLPS-Pes-0265Pelodiscus sinensis93.940.01307
LLPS-Aon-3621Aotus nancymaae93.90.01343
LLPS-Anc-3765Anolis carolinensis93.120.01285
LLPS-Pap-3223Pan paniscus92.850.01320
LLPS-Mod-3063Monodelphis domestica92.840.01344
LLPS-Sus-1208Sus scrofa92.730.01375
LLPS-Lac-2056Latimeria chalumnae91.590.01295
LLPS-Leo-3333Lepisosteus oculatus91.10.01286
LLPS-Urm-3780Ursus maritimus90.260.01158
LLPS-Ten-0552Tetraodon nigroviridis90.050.01274
LLPS-Scf-3354Scleropages formosus89.530.01269
LLPS-Asm-3044Astyanax mexicanus89.150.01240
LLPS-Orn-2852Oreochromis niloticus89.020.01266
LLPS-Dar-3665Danio rerio89.00.01260
LLPS-Gaa-0747Gasterosteus aculeatus88.750.01259
LLPS-Tar-1007Takifugu rubripes88.390.01266
LLPS-Fia-2062Ficedula albicollis88.320.01130
LLPS-Icp-2989Ictalurus punctatus88.250.01238
LLPS-Pof-3250Poecilia formosa86.880.01249
LLPS-Scm-0078Scophthalmus maximus86.770.01245
LLPS-Xim-0814Xiphophorus maculatus85.730.01243
LLPS-Orl-3633Oryzias latipes85.360.01236
LLPS-Meg-0961Meleagris gallopavo84.660.01030
LLPS-Drm-1778Drosophila melanogaster83.470.0 648
LLPS-Xet-0084Xenopus tropicalis64.446e-42 156
LLPS-Caf-4670Canis familiaris62.920.0 787
LLPS-Ora-2425Ornithorhynchus anatinus26.372e-1686.7
LLPS-Tag-1264Taeniopygia guttata24.713e-1685.9