Danio rerio      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Dar-0137
ENSDARG00000059246.7
2
LLPS-Dar-0432
ENSDARG00000035324.7
A0A2R8RN29
hnrnpl
3
LLPS-Dar-0145
ENSDARG00000007034.12
B8JLJ8
hnrpkl
4
LLPS-Dar-3549
ENSDARG00000070475.5
Q6NW62
khdrbs1b
5
LLPS-Dar-2022
ENSDARG00000069469.6
Q08BJ2
khdrbs2
6
LLPS-Dar-2317
ENSDARG00000101020.2
A0A0R4IJS6
khdrbs3
7
LLPS-Dar-0549
ENSDARG00000003527.11
Q6NYD4
mak16
8
LLPS-Dar-3044
ENSDARG00000045372.7
Q6PFJ1
ngdn
9
LLPS-Dar-1484
ENSDARG00000018494.7
Q9W6S8
smn1
10
LLPS-Dar-3665
ENSDARG00000069006.8
O13168
tle3b
11
LLPS-Dar-3171
ENSDARG00000051953.5
B8JMA3
ythdc1