LLPS-Dar-3171
ythdc1

▼ OVERVIEW

Status: Unreviewed
Protein Name: YTH domain-containing 1
Gene Name: ythdc1
Ensembl Gene: ENSDARG00000051953.5
Ensembl Protein: ENSDARP00000068161.4
Organism: Danio rerio
Taxa ID: 7955
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nuclear speckle, Nucleolus, Sam68 nuclear bodyPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSDART00000073671.5ENSDARP00000068161.4
UniProtB8JMA3, B8JMA3_DANRE
GeneBankCU571335
Entrez492769

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSVDRRDEKD  GELNVLEDIL  TDAPDQDDEL  YNPESEHDVN  EKKGSKRKHD  RGDAQDAKRL  60
61    RASGHNTRQP  MKRAAPSSGS  NGKKTSNPRG  RHAPEDLYDD  RKNHSGRGGA  SRADLSKGYG  120
121   EKGLSSSRDS  QRRIKPLMPE  LTEKMRRTSE  ESAGRASRSS  REEEAHSEEY  ATGSSVASSE  180
181   GNCSDVEEEG  AMPEEGEEKE  GEEEEEEEEE  GDDDDDEEEE  YVLEEEDARE  GNEQNDYDTR  240
241   SEASDSRSES  VSFSDEESVH  SASGSDASGS  EKKHEKLSSS  VRDVRKDRIN  KLKHILREAR  300
301   FFLIKSNNHE  NVSLAKAKGV  WSTLPVNEKK  LNAAFRAARS  VVLIFSVRES  GKFQGFARLS  360
361   SESHHGGSPI  HWVLPAGMNA  KMLGGVFKID  WICRRELPFT  KTAHLANPWN  EHKPVKIGRD  420
421   GQEIEPECGT  ELCMLFPHDE  SIDLYQVIHK  MRHKRRMHSE  PRSRGRLPHR  EPVPRDMGRR  480
481   RPEEYDMHNR  KRPRIDYTPE  FPQRPGFMQD  PRNPPVDRRF  SGVRRDVFLN  GSYNDYMREF  540
541   HHNIGPPPPW  QGMAPYPGME  HPPQHPYYQH  HPPPPQAHPP  YSGHHPMPHD  ARFREKRVVR  600
601   SFASSLHDYD  MRVDDFLRRT  QAVVSGRRSR  PRERDRQRER  DRPRDGRRDR  ERERGRERDR  660
661   ERERIRDRER  EKERGRYRR  679
Nucleotide CDS Sequence (FASTA)
1     ATGTCCGTCG  ACAGGAGAGA  CGAGAAAGAC  GGGGAACTCA  ATGTGCTGGA  AGACATTTTG  60
61    ACTGATGCTC  CTGACCAGGA  CGACGAGCTC  TACAATCCTG  AAAGTGAACA  TGATGTTAAC  120
121   GAGAAAAAAG  GGTCTAAAAG  GAAGCACGAT  CGAGGGGATG  CTCAGGATGC  GAAGCGCCTG  180
181   CGAGCTTCAG  GACACAACAC  CAGACAACCA  ATGAAAAGAG  CTGCTCCTTC  TTCTGGGTCA  240
241   AACGGTAAAA  AGACCAGCAA  TCCCAGAGGA  AGACACGCAC  CAGAAGATCT  ATATGATGAC  300
301   AGAAAGAACC  ATTCTGGAAG  AGGAGGTGCG  TCTCGGGCTG  ATCTGTCGAA  AGGATATGGT  360
361   GAAAAAGGCC  TGTCCAGCAG  CAGAGACTCA  CAGAGACGGA  TCAAACCATT  GATGCCTGAG  420
421   CTGACAGAGA  AGATGCGGAG  AACCAGTGAG  GAGAGTGCAG  GCAGAGCAAG  TCGATCCTCC  480
481   AGGGAAGAGG  AGGCTCATTC  AGAAGAATAT  GCCACCGGCA  GCTCCGTGGC  TTCGTCAGAA  540
541   GGAAACTGCT  CAGACGTTGA  AGAGGAAGGA  GCCATGCCGG  AGGAAGGAGA  AGAGAAGGAA  600
601   GGAGAGGAGG  AAGAGGAGGA  AGAAGAAGAG  GGAGATGACG  ACGATGATGA  AGAGGAAGAG  660
661   TATGTGCTGG  AGGAGGAGGA  CGCTCGTGAG  GGAAATGAAC  AGAATGACTA  TGACACTCGC  720
721   AGTGAGGCCA  GTGACTCCCG  CTCTGAGTCG  GTGTCGTTCT  CAGATGAAGA  GTCTGTGCAT  780
781   TCAGCATCAG  GCTCAGACGC  GTCAGGTTCT  GAAAAGAAAC  ATGAAAAACT  GTCCTCGTCT  840
841   GTCAGAGATG  TGAGGAAGGA  TCGGATCAAC  AAGCTGAAGC  ACATCTTGAG  AGAGGCCAGG  900
901   TTTTTTCTCA  TTAAGAGCAA  CAATCATGAG  AACGTTTCCC  TGGCTAAAGC  GAAGGGCGTG  960
961   TGGTCCACTC  TGCCTGTCAA  CGAGAAAAAA  CTCAATGCTG  CTTTTCGCGC  TGCTCGAAGT  1020
1021  GTTGTGCTCA  TTTTTTCAGT  CAGGGAGAGT  GGGAAATTTC  AAGGTTTTGC  ACGGCTGTCC  1080
1081  TCAGAGTCTC  ATCATGGAGG  ATCTCCCATA  CACTGGGTTT  TGCCTGCAGG  CATGAATGCC  1140
1141  AAGATGCTTG  GAGGGGTCTT  TAAAATTGAC  TGGATTTGCA  GGCGGGAATT  ACCTTTCACC  1200
1201  AAAACGGCTC  ATCTTGCTAA  CCCATGGAAT  GAGCACAAGC  CTGTGAAGAT  CGGACGTGAC  1260
1261  GGACAGGAGA  TTGAACCAGA  GTGCGGGACG  GAGCTCTGCA  TGCTCTTCCC  CCACGACGAG  1320
1321  AGCATTGATT  TGTATCAGGT  CATTCACAAA  ATGCGCCACA  AGAGGAGGAT  GCACTCAGAG  1380
1381  CCTCGATCTC  GGGGCCGACT  GCCCCACAGA  GAGCCCGTCC  CTCGGGACAT  GGGAAGGCGT  1440
1441  CGACCGGAGG  AATATGACAT  GCACAACCGG  AAGCGGCCCA  GGATTGATTA  CACCCCAGAA  1500
1501  TTCCCCCAAA  GACCAGGTTT  TATGCAAGAT  CCCCGAAATC  CACCTGTGGA  CAGGCGCTTT  1560
1561  TCTGGTGTTA  GAAGAGACGT  GTTTCTTAAT  GGATCCTACA  ACGACTATAT  GAGAGAATTC  1620
1621  CATCACAACA  TTGGGCCTCC  ACCACCTTGG  CAAGGAATGG  CCCCATACCC  TGGTATGGAG  1680
1681  CATCCTCCTC  AGCACCCGTA  TTACCAGCAC  CACCCTCCTC  CACCCCAGGC  CCACCCGCCT  1740
1741  TACTCTGGAC  ACCACCCCAT  GCCCCATGAT  GCCCGCTTCA  GGGAAAAGAG  GGTTGTCCGC  1800
1801  TCTTTCGCCT  CCAGTTTGCA  TGATTACGAC  ATGCGCGTGG  ATGATTTTCT  AAGGCGAACG  1860
1861  CAGGCAGTGG  TGAGCGGACG  CAGAAGCAGA  CCGCGGGAGA  GAGACCGTCA  GAGAGAGCGT  1920
1921  GACCGACCCA  GAGACGGACG  GAGAGACCGA  GAGCGAGAAC  GTGGACGGGA  GCGGGACCGC  1980
1981  GAGAGAGAGA  GAATTCGAGA  CCGCGAGAGA  GAAAAGGAGA  GAGGCCGATA  CCGGAGATAG  2040

▼ ANNOTATION

Disorder
D2P2IUPred2A
Interaction
RAINMIST
Physicochemical
AAindex

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Asm-1350Astyanax mexicanus84.790.0 888
LLPS-Mup-2473Mustela putorius furo84.510.0 583
LLPS-Aim-0321Ailuropoda melanoleuca84.510.0 584
LLPS-Fia-1954Ficedula albicollis84.510.0 550
LLPS-Fec-1512Felis catus84.510.0 584
LLPS-Caf-1245Canis familiaris84.510.0 584
LLPS-Eqc-0613Equus caballus84.510.0 584
LLPS-Myl-2583Myotis lucifugus84.240.0 582
LLPS-Otg-2911Otolemur garnettii84.240.0 555
LLPS-Orc-1010Oryctolagus cuniculus84.240.0 553
LLPS-Meg-2373Meleagris gallopavo84.240.0 555
LLPS-Sah-1975Sarcophilus harrisii83.970.0 549
LLPS-Mod-2421Monodelphis domestica83.970.0 551
LLPS-Caj-3661Callithrix jacchus83.70.0 551
LLPS-Chs-0634Chlorocebus sabaeus83.70.0 550
LLPS-Ere-0675Erinaceus europaeus83.70.0 578
LLPS-Ova-0690Ovis aries83.70.0 578
LLPS-Bot-3043Bos taurus83.70.0 578
LLPS-Cas-3125Carlito syrichta83.70.0 551
LLPS-Poa-0537Pongo abelii83.70.0 546
LLPS-Fud-3882Fukomys damarensis83.150.0 546
LLPS-Tut-0829Tursiops truncatus83.150.0 570
LLPS-Sus-4004Sus scrofa82.710.0 576
LLPS-Loa-0260Loxodonta africana82.450.0 548
LLPS-Lac-0495Latimeria chalumnae82.340.0 573
LLPS-Anc-1628Anolis carolinensis82.070.0 541
LLPS-Gog-3576Gorilla gorilla81.910.0 543
LLPS-Maf-3400Macaca fascicularis81.910.0 543
LLPS-Ora-2419Ornithorhynchus anatinus81.912e-180 538
LLPS-Cea-3347Cercocebus atys81.910.0 543
LLPS-Aon-1991Aotus nancymaae81.910.0 543
LLPS-Mal-1172Mandrillus leucophaeus81.910.0 543
LLPS-Paa-2271Papio anubis81.910.0 543
LLPS-Dio-1761Dipodomys ordii81.910.0 541
LLPS-Rhb-2397Rhinopithecus bieti81.910.0 542
LLPS-Pat-3229Pan troglodytes81.910.0 543
LLPS-Pap-0161Pan paniscus81.910.0 543
LLPS-Hos-0718Homo sapiens81.910.0 543
LLPS-Man-1386Macaca nemestrina81.910.0 543
LLPS-Ict-0237Ictidomys tridecemlineatus81.910.0 543
LLPS-Mam-1038Macaca mulatta81.910.0 543
LLPS-Mea-0003Mesocricetus auratus81.650.0 541
LLPS-Mum-0147Mus musculus81.380.0 541
LLPS-Ran-4411Rattus norvegicus81.380.0 540
LLPS-Nol-1230Nomascus leucogenys81.122e-177 530
LLPS-Leo-0352Lepisosteus oculatus78.220.0 585
LLPS-Icp-0047Ictalurus punctatus77.390.0 847
LLPS-Tar-0016Takifugu rubripes76.922e-1067.8
LLPS-Ten-2806Tetraodon nigroviridis73.543e-172 514
LLPS-Cap-3131Cavia porcellus72.552e-152 464
LLPS-Scf-1124Scleropages formosus69.980.0 775
LLPS-Scm-3315Scophthalmus maximus69.661e-165 498
LLPS-Orl-1551Oryzias latipes69.294e-160 485
LLPS-Pof-2865Poecilia formosa68.654e-161 486
LLPS-Xim-1631Xiphophorus maculatus68.387e-161 486
LLPS-Gaa-2872Gasterosteus aculeatus63.627e-155 471
LLPS-Gaga-1066Gallus gallus62.220.0 613
LLPS-Xet-1531Xenopus tropicalis61.350.0 597
LLPS-Tag-2123Taeniopygia guttata61.290.0 624
LLPS-Pes-0498Pelodiscus sinensis61.180.0 607
LLPS-Anp-1175Anas platyrhynchos59.940.0 593
LLPS-Drm-0427Drosophila melanogaster56.321e-58 216
LLPS-Urm-0028Ursus maritimus47.896e-31 134
LLPS-Glm-1492Glycine max45.992e-30 128
LLPS-Orn-0572Oreochromis niloticus44.935e-32 137
LLPS-Dac-1993Daucus carota44.239e-29 122
LLPS-Prp-1039Prunus persica43.621e-29 125
LLPS-Tum-0558Tuber melanosporum42.683e-31 135
LLPS-Thc-2024Theobroma cacao41.894e-28 121
LLPS-Gor-1147Gossypium raimondii40.06e-29 124
LLPS-Gag-0964Gaeumannomyces graminis38.855e-23 108
LLPS-Coc-1581Corchorus capsularis38.293e-28 121
LLPS-Map-0962Magnaporthe poae37.412e-21 103
LLPS-Amt-1120Amborella trichopoda37.372e-27 119
LLPS-Zyt-0925Zymoseptoria tritici36.968e-1783.6
LLPS-Phv-1253Phaseolus vulgaris36.446e-31 129
LLPS-Trr-0776Trichoderma reesei36.434e-21 100
LLPS-Trv-0588Trichoderma virens36.37e-2094.0
LLPS-Mae-2417Manihot esculenta36.232e-26 115
LLPS-Scs-0046Sclerotinia sclerotiorum35.713e-1893.6
LLPS-Crn-1452Cryptococcus neoformans31.722e-1171.6
LLPS-Hea-2571Helianthus annuus31.332e-1274.7
LLPS-Met-0349Medicago truncatula31.032e-1274.3
LLPS-Nia-1990Nicotiana attenuata31.036e-1376.3
LLPS-Brr-2757Brassica rapa30.911e-1480.9
LLPS-Cii-1680Ciona intestinalis30.823e-1273.9
LLPS-Miv-1139Microbotryum violaceum30.632e-1172.0
LLPS-Brn-0343Brassica napus30.464e-1479.0
LLPS-Sol-2040Solanum lycopersicum30.341e-1275.5
LLPS-Vir-2198Vigna radiata30.344e-1479.7
LLPS-Sot-1411Solanum tuberosum30.342e-1274.3
LLPS-Art-1643Arabidopsis thaliana30.061e-1480.9
LLPS-Cis-1127Ciona savignyi29.872e-1170.9
LLPS-Orbr-1692Oryza brachyantha29.763e-1480.1
LLPS-Pot-0726Populus trichocarpa29.669e-1272.4
LLPS-Bro-1863Brassica oleracea29.484e-1479.0
LLPS-Arl-1240Arabidopsis lyrata29.455e-1479.0
LLPS-Orb-0297Oryza barthii29.337e-1272.4
LLPS-Orp-2191Oryza punctata29.335e-1273.2
LLPS-Orr-2410Oryza rufipogon29.338e-1272.4
LLPS-Cus-1631Cucumis sativus29.258e-1479.0
LLPS-Via-0528Vigna angularis28.659e-1169.3
LLPS-Tru-0335Triticum urartu28.652e-1068.2
LLPS-Hov-0858Hordeum vulgare28.282e-1171.2
LLPS-Mua-0750Musa acuminata28.264e-1170.5
LLPS-Sem-1795Selaginella moellendorffii28.247e-1269.3
LLPS-Ori-1660Oryza indica28.213e-1170.9
LLPS-Orgl-1504Oryza glumaepatula28.212e-1171.2
LLPS-Ors-1759Oryza sativa28.211e-1172.0
LLPS-Org-2156Oryza glaberrima28.211e-1172.0
LLPS-Zem-1363Zea mays28.05e-1273.2
LLPS-Sob-0226Sorghum bicolor27.875e-1170.1
LLPS-Sei-2062Setaria italica27.721e-1068.9
LLPS-Orni-1115Oryza nivara27.224e-1273.6
LLPS-Brd-2434Brachypodium distachyon27.222e-1274.7
LLPS-Orm-2050Oryza meridionalis27.224e-1273.6
LLPS-Tra-0547Triticum aestivum26.74e-1377.0
LLPS-Mel-0946Melampsora laricipopulina25.978e-1269.3
LLPS-Lep-1818Leersia perrieri25.584e-1273.2
LLPS-Viv-1523Vitis vinifera25.415e-1273.6