Bos taurus      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 13 genes.  Reviewed (2 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Bot-0192
ENSBTAG00000021131.5
Q3T0D0
HNRNPK
2
LLPS-Bot-0185
ENSBTAG00000009595.4
Q2KII6
NGDN
3
LLPS-Bot-4070
ENSBTAG00000001553.6
P09867
HNRNPA1
4
LLPS-Bot-0281
ENSBTAG00000013952.6
A6H6Y0
HNRNPD
5
LLPS-Bot-1088
ENSBTAG00000001055.6
E1BIB4
HNRNPL
6
LLPS-Bot-3098
ENSBTAG00000012497.4
Q29RQ2
KHDRBS1
7
LLPS-Bot-1859
ENSBTAG00000043990.3
E1BP48
KHDRBS2
8
LLPS-Bot-2568
ENSBTAG00000002181.6
A4FV24
KHDRBS3
9
LLPS-Bot-1028
ENSBTAG00000033504.2
Q1RML7
MAK16
10
LLPS-Bot-1570
ENSBTAG00000013308.6
D3JUI8
RBMX
11
LLPS-Bot-0998
ENSBTAG00000005743.6
O18870
SMN1
12
LLPS-Bot-1284
ENSBTAG00000015580.6
F1ML22
TLE3
13
LLPS-Bot-3043
ENSBTAG00000015572.6
F1MIW9
YTHDC1