Homo sapiens      Receptor cluster


※ Receptor cluster introduction

    One of the most actively studied areas in which spatial heterogeneity is emerging as a key factor is signal transduction at the cell membrane. In addition to imposing a quasi-two-dimensional geometry, the membrane plays host to a large diversity of cellular components, and interactions among these components give rise to a complex spatial organization. A central theme of recent work in this field is the prevalence and role of membrane clusters, groups of colocalized molecules that often participate in the detection of external signals and subsequently drive responses within the cell (1).

Reference
1. Mugler A., et al (2012) Membrane Clustering and the Role of Rebinding in Biochemical Signaling. Biophys J, 102(5): 1069–1078. PMID: 22404929


There are 9 genes.  Reviewed (8 or Unreviewed (1

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Hos-2393
ENSG00000164047.4
P49913
CAMP
2
LLPS-Hos-1708
ENSG00000001626.15
P13569
CFTR
3
LLPS-Hos-0796
ENSG00000113263.12
Q08881
ITK
4
LLPS-Hos-2734
ENSG00000172572.6
Q14432
PDE3A
5
LLPS-Hos-5014
ENSG00000196396.9
P18031
PTP1B
6
LLPS-Hos-3819
ENSG00000132639.12
P60880
SNAP25
7
LLPS-Hos-3487
ENSG00000106089.11
Q16623
STX1A
8
LLPS-Hos-1656
ENSG00000165025.14
P43405
SYK
9
LLPS-Hos-4872
ENSG00000181856.14
P14672
SLC2A4