Zea mays      Nuclear speckle


※ Nuclear speckle introduction

    Nuclear speckles or splicing speckles, also known as interchromatin granule clusters, are membrane-less nuclear organelles enriched in pre-mRNA splicing and transcription factors and play important roles in RNA metabolism, such as transcription, pre-mRNA splicing, 3′-end mRNA processing, and execution of mRNA nuclear export (1; 2). They are dynamic subnuclear structures, and their size, shape, and number can vary accompanied with RNA regulation, nuclear speckles disperse in high activity of mRNA processing when transcription or pre-mRNA splicing is inhibited, GSK-3β can regulate assembly of nuclear speckles (2). Because many naturally intronless mRNAs, including eight exogenously expressed and four endogenous ones, are proved to be associate with NSs, So Nuclear speckles (NSs) are thought to serve as splicing factor storage sites (3).

Reference
1. Lee, K. H., Zhang, P., Kim, H. J., Mitrea, D. M., Sarkar, M., Freibaum, B. D., et al. (2016) C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles. Cell, 167(3), 774-788 e717. PMID: 27768896
2. Wang, K., Wang, L., Wang, J., Chen, S., Shi, M., & Cheng, H. (2018) Intronless mRNAs transit through nuclear speckles to gain export competence. J Cell Biol, 217(11), 3912-3929. PMID: 30194269
3. An, Y., Zou, Y., Cao, Y., Yao, M., Ma, N., Wu, Y., et al. (2019) The nuclear GSK-3beta regulated post-transcriptional processing of mRNA through phosphorylation of SC35. Mol Cell Biochem, 451(1-2), 55-67. PMID: 30030778


There are 59 genes.  Reviewed (0 or Unreviewed (59

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Zem-1030
Zm00001d020706
B4F9V3
100191706
2
LLPS-Zem-1594
Zm00001d017096
A0A1D6HC42
100193059
3
LLPS-Zem-0234
Zm00001d043843
B4FL42
100217051
4
LLPS-Zem-0335
Zm00001d029256
A0A1D6K3W5
100272550
5
LLPS-Zem-1310
Zm00001d028529
B4FPG3
100272589
6
LLPS-Zem-1360
Zm00001d006906
A0A1D6F1Z3
100272627
7
LLPS-Zem-1368
Zm00001d013094
B4FQ32
100272712
8
LLPS-Zem-0774
Zm00001d010476
B4FQK6
100272776
9
LLPS-Zem-0147
Zm00001d017153
A0A1D6HCP2
100273852
10
LLPS-Zem-2152
Zm00001d016801
B4FY38
100273912
11
LLPS-Zem-0332
Zm00001d015248
A0A1D6H0Q8
100277544
12
LLPS-Zem-1339
Zm00001d052138
A0A1D6QDP5
100279342
13
LLPS-Zem-0519
Zm00001d028655
B6T346
100279524
14
LLPS-Zem-0971
Zm00001d018545
B6SWH5
100281557
15
LLPS-Zem-0775
Zm00001d012042
A0A1D6G673
100281934
16
LLPS-Zem-0340
Zm00001d029303
B4FSC7
100282469
17
LLPS-Zem-0344
Zm00001d034710
A0A1D6LA85
100282627
18
LLPS-Zem-1774
Zm00001d025460
B4FXQ9
100282954
19
LLPS-Zem-0362
Zm00001d047699
B4FK63
100283511
20
LLPS-Zem-0015
Zm00001d043137
A0A1D6N969
100283656
21
LLPS-Zem-1277
Zm00001d045507
A0A1D6NWE2
100283946
22
LLPS-Zem-0483
Zm00001d032763
B6TRQ7
100284255
23
LLPS-Zem-1688
Zm00001d007133
A0A1D6F447
100284501
24
LLPS-Zem-1316
Zm00001d040357
A0A1D6MQC3
100284614
25
LLPS-Zem-0388
Zm00001d026587
B6U194
100285144
26
LLPS-Zem-1798
Zm00001d018793
B6U9K4
100285773
27
LLPS-Zem-1871
Zm00001d048777
A0A1D6PPZ8
100286059
28
LLPS-Zem-0913
Zm00001d015499
A0A1D6H2E4
100304259
29
LLPS-Zem-2101
Zm00001d002418
A0A1D6E0J9
100304314
30
LLPS-Zem-0437
Zm00001d028579
A0A1D6JXU1
100304415
31
LLPS-Zem-1952
Zm00001d033511
C0P2Q6
100381912
32
LLPS-Zem-0912
Zm00001d025222
C0PE44
100383202
33
LLPS-Zem-0130
Zm00001d021137
A0A1D6I8I0
100383273
34
LLPS-Zem-0911
Zm00001d040343
C0PG74
100383468
35
LLPS-Zem-2521
Zm00001d003049
A0A1D6E658
100383522
36
LLPS-Zem-1139
Zm00001d034914
A0A1D6LCD9
100384227
37
LLPS-Zem-0421
Zm00001d036301
A0A1D6LLK8
103629533
38
LLPS-Zem-0122
Zm00001d022286
A0A1D6IKW3
103633484
39
LLPS-Zem-2547
Zm00001d029096
A0A1D6K2K2
103634632
40
LLPS-Zem-0221
Zm00001d024729
B4FEN6
103641344
41
LLPS-Zem-0642
Zm00001d007871
A0A1D6F9E1
103648272
42
LLPS-Zem-1697
Zm00001d051061
B6T273
103653754
43
LLPS-Zem-0614
Zm00001d053524
K7V5J0
103654761
44
LLPS-Zem-2420
Zm00001d036296
Q8S4P6
EZ1
45
LLPS-Zem-1568
Zm00001d017177
B4F7Z5
RSZ28
46
LLPS-Zem-1065
Zm00001d047401
B4FET2
SCL25A
47
LLPS-Zem-0338
Zm00001d011150
A0A1D6FX10
ZEAMMB73_Zm00001d011150
48
LLPS-Zem-1263
Zm00001d014343
A0A1D6GSC7
ZEAMMB73_Zm00001d014343
49
LLPS-Zem-2492
Zm00001d014813
A0A1D6GWK1
ZEAMMB73_Zm00001d014813
50
LLPS-Zem-0275
Zm00001d027556
A0A1D6JMZ5
ZEAMMB73_Zm00001d027556
51
LLPS-Zem-0651
Zm00001d028668
B4FMP2
ZEAMMB73_Zm00001d028668
52
LLPS-Zem-0945
Zm00001d030739
A0A1D6KE50
ZEAMMB73_Zm00001d030739
53
LLPS-Zem-0414
Zm00001d033309
A0A1D6KXM9
ZEAMMB73_Zm00001d033309
54
LLPS-Zem-0074
Zm00001d033646
A0A1D6L113
ZEAMMB73_Zm00001d033646
55
LLPS-Zem-1821
Zm00001d035019
A0A1D6LDM1
ZEAMMB73_Zm00001d035019
56
LLPS-Zem-0621
Zm00001d037200
B4FZJ1
ZEAMMB73_Zm00001d037200
57
LLPS-Zem-0266
Zm00001d037602
C0PM53
ZEAMMB73_Zm00001d037602
58
LLPS-Zem-0134
Zm00001d042287
A0A1D6N2M1
ZEAMMB73_Zm00001d042287
59
LLPS-Zem-0446
Zm00001d045282
K7W6D2
ZEAMMB73_Zm00001d045282