Meleagris gallopavo      Neuronal granule


※ Neuronal granule introduction

    Neuronal granules are also referred to as neuronal transport granules, RNA-transporting granules, neuronal RNA granules, dendritic P-body like structures (dlP-bodies), FMRP granules and Staufen granules(1,2). They are broadly identified by the presence of two highly conserved proteins: Staufen, a double-stranded RNA-binding protein and FMRP. As a kind of cytoplasmic RNP bodies located in Cytoplasm of neurons, neuronal transport RNPs have highly specialized functions and have been shown to interact or co-localize with components of GW/P bodies (1), it's microtubule-dependent and contain Silenced mRNAs and ribosomes components. Neuronal RNA bodies is of spherical shape with fluid characteristics, proved to be associated with rotein synthesis in response to exogenous stimuli (2).

Reference
1. Moser, J. J., & Fritzler, M. J. (2013) Relationship of other cytoplasmic ribonucleoprotein bodies (cRNPB) to GW/P bodies. Adv Exp Med Biol, 768, 213-242. PMID: 23224973
2. Hirano, M., Muto, M., Sakai, M., Kondo, H., Kobayashi, S., Kariwa, H., Yoshii, K.(2017) Dendritic transport of tick-borne flavivirus RNA by neuronal granules affects development of neurological disease. Proc Natl Acad Sci U S A, 114, 9960–9965. PMID: 28847946
3. Darling, A. L., Liu, Y., Oldfield, C. J., & Uversky, V. N. (2018) Intrinsically Disordered Proteome of Human Membrane-Less Organelles. Proteomics, 18(5-6), e1700193. PMID: 27838525


There are 34 genes.  Reviewed (0 or Unreviewed (34

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Meg-0683
ENSMGAG00000014566.2
G1NP03
2
LLPS-Meg-1589
ENSMGAG00000007630.2
H9H1A1
3
LLPS-Meg-1194
ENSMGAG00000010122.2
G1NCL5
CAPRIN1
4
LLPS-Meg-2138
ENSMGAG00000003660.2
G1MX60
CPEB4
5
LLPS-Meg-1520
ENSMGAG00000014025.2
G1NML8
DDX1
6
LLPS-Meg-0145
ENSMGAG00000014609.1
G1NP43
DDX3X
7
LLPS-Meg-0142
ENSMGAG00000007667.2
G1N6U2
DDX5
8
LLPS-Meg-0509
ENSMGAG00000010935.1
G1NEN3
EIF2A
9
LLPS-Meg-0293
ENSMGAG00000011974.2
G1NHC2
EIF2S1
10
LLPS-Meg-1336
ENSMGAG00000002174.2
G1MTK6
EIF2S2
11
LLPS-Meg-1953
ENSMGAG00000011171.2
G1NF97
EIF4E
12
LLPS-Meg-2847
ENSMGAG00000010928.2
G1NEN2
ELAVL4
13
LLPS-Meg-0473
ENSMGAG00000005282.2
G3USZ2
EWSR1
14
LLPS-Meg-1667
ENSMGAG00000008270.2
G1N897
FMR1
15
LLPS-Meg-0308
ENSMGAG00000005963.2
G1N2T7
G3BP1
16
LLPS-Meg-0295
ENSMGAG00000010635.1
G1NDW3
HNRNPA2B1
17
LLPS-Meg-2328
ENSMGAG00000007727.2
G1N6X6
HNRNPAB
18
LLPS-Meg-2253
ENSMGAG00000008051.1
G1N7M9
HNRNPD
19
LLPS-Meg-0910
ENSMGAG00000011427.2
G1NG01
HNRNPU
20
LLPS-Meg-1467
ENSMGAG00000004455.2
G1MZ53
KHDRBS1
21
LLPS-Meg-1938
ENSMGAG00000008028.1
G1N7L8
MAPK8
22
LLPS-Meg-0633
ENSMGAG00000008869.2
G1MYJ8
NONO
23
LLPS-Meg-a053
ENSMGAG00000007010.2
G1N597
PSD
24
LLPS-Meg-0529
ENSMGAG00000015134.1
G1NQG1
PSPC1
25
LLPS-Meg-1506
ENSMGAG00000005088.1
G1N0K6
RBPMS
26
LLPS-Meg-0232
ENSMGAG00000012376.2
G1NIE8
RPL3
27
LLPS-Meg-3317
ENSMGAG00000012805.1
G1NJI7
RTCB
28
LLPS-Meg-1570
ENSMGAG00000013784.2
G1NLZ3
RTRAF
29
LLPS-Meg-1816
ENSMGAG00000004237.2
G1MYK0
SFPQ
30
LLPS-Meg-3329
ENSMGAG00000005772.2
G1N290
SRSF10
31
LLPS-Meg-1772
ENSMGAG00000004719.1
G1MZS7
STAU1
32
LLPS-Meg-1351
ENSMGAG00000011523.2
G1NG85
STAU2
33
LLPS-Meg-1264
ENSMGAG00000013690.2
G3US02
SYNCRIP
34
LLPS-Meg-1510
ENSMGAG00000001098.1
G1MR29
TRIM2