Macaca mulatta      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 38 genes.  Reviewed (0 or Unreviewed (38

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Mam-1079
ENSMMUG00000014387.3
F7CLL2
AARS2
2
LLPS-Mam-2466
ENSMMUG00000030408.2
A0A1D5Q3R2
ATP5MF
3
LLPS-Mam-0301
ENSMMUG00000022798.3
F6UXG7
DARS2
4
LLPS-Mam-3859
ENSMMUG00000010836.3
F6RNH5
DDX28
5
LLPS-Mam-0249
ENSMMUG00000003820.3
F7HRC0
DHX30
6
LLPS-Mam-3470
ENSMMUG00000002776.3
F7H299
ERAL1
7
LLPS-Mam-1805
ENSMMUG00000020459.3
F6VYK7
FASTK
8
LLPS-Mam-3588
ENSMMUG00000020511.3
F7B2Z9
FASTKD1
9
LLPS-Mam-1274
ENSMMUG00000017735.3
F7F3Y0
FASTKD2
10
LLPS-Mam-4315
ENSMMUG00000002982.3
F7GW50
FASTKD5
11
LLPS-Mam-2353
ENSMMUG00000000380.3
F6X6F5
GRSF1
12
LLPS-Mam-3646
ENSMMUG00000009296.3
F7H1H7
HSD17B10
13
LLPS-Mam-3647
ENSMMUG00000019875.3
F7GTA8
KIAA0391
14
LLPS-Mam-3563
ENSMMUG00000020402.3
A0A1D5QDI3
MCU
15
LLPS-Mam-1621
ENSMMUG00000022001.3
A0A1D5Q5Y2
ME2
16
LLPS-Mam-0440
ENSMMUG00000000622.3
F6Y1D2
MRM1
17
LLPS-Mam-3741
ENSMMUG00000017020.3
F6PKI3
MRM2
18
LLPS-Mam-4494
ENSMMUG00000023758.3
G7NAG1
MRPL19
19
LLPS-Mam-0889
ENSMMUG00000010679.3
F7AXE6
MRPL43
20
LLPS-Mam-0748
ENSMMUG00000009744.3
F6ZQ94
MRPL47
21
LLPS-Mam-4321
ENSMMUG00000017905.2
A0A1D5R0Z4
MRPS27
22
LLPS-Mam-3124
ENSMMUG00000001899.3
F7FX49
MRPS31
23
LLPS-Mam-1455
ENSMMUG00000048488.1
A0A1D5QNG0
MRPS7
24
LLPS-Mam-1331
ENSMMUG00000019682.3
F7CGI1
MRPS9
25
LLPS-Mam-0923
ENSMMUG00000008808.3
A0A1D5RCQ7
MTERF3
26
LLPS-Mam-3704
ENSMMUG00000003001.3
F6VV65
MTPAP
27
LLPS-Mam-4571
ENSMMUG00000012189.3
F7HTM8
NLRX1
28
LLPS-Mam-0717
ENSMMUG00000022530.3
F6YGZ5
NOA1
29
LLPS-Mam-1745
ENSMMUG00000003429.3
F7F9E1
PMPCB
30
LLPS-Mam-3457
ENSMMUG00000007003.3
F7DK85
PNPT1
31
LLPS-Mam-1415
ENSMMUG00000017908.3
A0A1D5QJU9
PTCD2
32
LLPS-Mam-1772
ENSMMUG00000010628.3
F7BJB7
RPUSD3
33
LLPS-Mam-4026
ENSMMUG00000007933.2
A0A1D5RD91
RPUSD4
34
LLPS-Mam-4070
ENSMMUG00000009693.3
F6Y3N7
SUCLG2
35
LLPS-Mam-4055
ENSMMUG00000011171.3
F6VAH2
TFB1M
36
LLPS-Mam-1229
ENSMMUG00000017780.3
F7EUC5
TRMT10C
37
LLPS-Mam-2213
ENSMMUG00000014146.3
F7BVF3
TRUB2
38
LLPS-Mam-2238
ENSMMUG00000016406.3
F7FYW1
YME1L1