Astyanax mexicanus      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 38 genes.  Reviewed (0 or Unreviewed (38

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Asm-0108
ENSAMXG00000007214.2
W5KIJ4
2
LLPS-Asm-0190
ENSAMXG00000043393.1
A0A3B1IMC4
3
LLPS-Asm-0237
ENSAMXG00000001955.2
W5K333
4
LLPS-Asm-0552
ENSAMXG00000009629.2
W5KQN8
5
LLPS-Asm-0969
ENSAMXG00000011888.2
W5KXA9
6
LLPS-Asm-0997
ENSAMXG00000012236.2
W5KYB1
7
LLPS-Asm-1008
ENSAMXG00000012316.2
W5KYL4
8
LLPS-Asm-1036
ENSAMXG00000029104.1
A0A3B1K690
9
LLPS-Asm-1043
ENSAMXG00000006286.2
W5KFT8
10
LLPS-Asm-1074
ENSAMXG00000034420.1
A0A3B1J332
11
LLPS-Asm-1160
ENSAMXG00000009658.2
A0A3B1KL41
12
LLPS-Asm-1177
ENSAMXG00000029404.1
A0A3B1K7N6
13
LLPS-Asm-1314
ENSAMXG00000014791.2
W5L5V6
14
LLPS-Asm-1485
ENSAMXG00000042804.1
A0A3B1KDF4
15
LLPS-Asm-1529
ENSAMXG00000020695.2
W5LNA1
16
LLPS-Asm-1637
ENSAMXG00000015074.2
W5L6R0
17
LLPS-Asm-1781
ENSAMXG00000037292.1
A0A3B1JEF3
18
LLPS-Asm-2067
ENSAMXG00000009468.2
W5KQ86
19
LLPS-Asm-2294
ENSAMXG00000001466.2
W5K1N2
20
LLPS-Asm-2469
ENSAMXG00000041378.1
A0A3B1IQ70
21
LLPS-Asm-2553
ENSAMXG00000014749.2
W5L5R8
22
LLPS-Asm-2617
ENSAMXG00000002310.2
W5K456
23
LLPS-Asm-2793
ENSAMXG00000018258.2
W5LG53
24
LLPS-Asm-2802
ENSAMXG00000004024.2
W5K952
25
LLPS-Asm-3176
ENSAMXG00000036128.1
A0A3B1JIY1
26
LLPS-Asm-3201
ENSAMXG00000031679.1
A0A3B1JE50
27
LLPS-Asm-3241
ENSAMXG00000004029.2
W5K957
28
LLPS-Asm-3419
ENSAMXG00000005842.2
W5KEH0
29
LLPS-Asm-3423
ENSAMXG00000039634.1
A0A3B1KD68
30
LLPS-Asm-3494
ENSAMXG00000005878.2
W5KEK4
31
LLPS-Asm-3543
ENSAMXG00000030559.1
A0A3B1IKK3
32
LLPS-Asm-3587
ENSAMXG00000030596.1
A0A3B1J774
33
LLPS-Asm-3851
ENSAMXG00000031796.1
A0A3B1KFP3
34
LLPS-Asm-4007
ENSAMXG00000037957.1
A0A3B1KIB6
35
LLPS-Asm-0609
ENSAMXG00000032017.1
A0A3B1K4H4
AARS
36
LLPS-Asm-1838
ENSAMXG00000025880.2
W5LTW9
FASTKD5
37
LLPS-Asm-1155
ENSAMXG00000042321.1
A0A3B1IVH5
PNPT1
38
LLPS-Asm-2536
ENSAMXG00000034435.1
A0A3B1JKQ9
SUCLG2