Ficedula albicollis      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 15 genes.  Reviewed (0 or Unreviewed (15

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Fia-1105
ENSFALG00000002782.1
U3JJH8
2
LLPS-Fia-2545
ENSFALG00000003360.1
U3JL61
3
LLPS-Fia-0153
ENSFALG00000003130.1
U3JKF6
CASP8AP2
4
LLPS-Fia-1022
ENSFALG00000002412.1
U3JIB5
CPSF2
5
LLPS-Fia-0520
ENSFALG00000006572.1
U3JVQ1
CPSF3
6
LLPS-Fia-2771
ENSFALG00000013799.1
U3KH95
CPSF4
7
LLPS-Fia-1191
ENSFALG00000007163.1
U3JXH5
CTCF
8
LLPS-Fia-2991
ENSFALG00000001017.1
U3JE52
CTR9
9
LLPS-Fia-0194
ENSFALG00000000666.1
U3JD35
DDX20
10
LLPS-Fia-0517
ENSFALG00000006269.1
U3JUT4
H2AFZ
11
LLPS-Fia-0357
ENSFALG00000006114.1
U3JUC5
HINFP
12
LLPS-Fia-2132
ENSFALG00000000851.1
U3JDM3
LSM10
13
LLPS-Fia-1287
ENSFALG00000008478.1
U3K1D5
LSM11
14
LLPS-Fia-1259
ENSFALG00000000456.1
U3JCG4
NPAT
15
LLPS-Fia-0800
ENSFALG00000013830.1
U3KHC9
TNRC18