※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094

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No.	Status	DrLLPS ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		LLPS-Cae-0816	WBGene00022301	Q9N4C2	cpsf-1
2		LLPS-Cae-1658	WBGene00017313	O17403	cpsf-2
3		LLPS-Cae-0668	WBGene00013460	Q95PY8	cpsf-3
4		LLPS-Cae-0637	WBGene00044329	Q7YTG9	cpsf-4
5		LLPS-Cae-1369	WBGene00007184	Q03560	ctr-9
6		LLPS-Cae-0522	WBGene00017988	A0A164D3G3	fipp-1
7		LLPS-Cae-1810	WBGene00009553	O45494	hinf-1
8		LLPS-Cae-1285	WBGene00019947	Q27511	htz-1
9		LLPS-Cae-0642	WBGene00017797	O16929	symk-1