Aspergillus nidulans      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Asn-0141
ANIA_03082
Q5B8P8
ANIA_03082
2
LLPS-Asn-0487
ANIA_11128
C8V9J3
ANIA_11128
3
LLPS-Asn-1075
ANIA_01413
Q5BDG7
cft1
4
LLPS-Asn-0866
ANIA_02433
Q5BAJ7
fip1
5
LLPS-Asn-0570
ANIA_08039
Q5AUJ1
htz1
6
LLPS-Asn-1214
ANIA_00990
Q5BEP0
ysh1
7
LLPS-Asn-0497
ANIA_00298
Q5BGN2
yth1