※ Droplet introduction

    Interactions between diverse synthetic, multivalent macromolecules (including multi-domain proteins and RNA) produce sharp liquid-liquid-demixing phase separations, generating micrometre-sized liquid droplets in aqueous solution (1-2). In vitro phase separation assays with purified proteins have become the standard way to investigate proteins that form membrane-less compartments. By now, various proteins have been purified and tested for their ability to phase separate and form liquid condensates in vitro (3).

References
1. Li P., Banjade S., Cheng H.C., et al. (2012) Phase transitions in the assembly of multivalent signalling proteins. Nature, 483, 336-40. PMID: 22398450
2. Kato M., Han T.W., Xie S., et al. (2012) Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels. Cell, 149, 753-67. PMID: 22579281
3. Alberti S., Saha S., Woodruff J.B., et al. (2018) A User’s Guide for Phase Separation Assays with Purified Proteins. J. Mol. Biol., 430, 4806-4820. PMID: 29944854

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No.	Status	DrLLPS ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		LLPS-Ora-0185	ENSOANG00000029956.1	K7EB73
2		LLPS-Ora-0287	ENSOANG00000014658.2	F7DSB1
3		LLPS-Ora-0434	ENSOANG00000004986.2	F7CX73
4		LLPS-Ora-0574	ENSOANG00000001666.1	F7GCL5
5		LLPS-Ora-0630	ENSOANG00000032164.1	K7E9I2
6		LLPS-Ora-0646	ENSOANG00000007408.3	F7CIG5
7		LLPS-Ora-0781	ENSOANG00000012232.2	F7FGT6
8		LLPS-Ora-0886	ENSOANG00000004888.2	F7FUC3
9		LLPS-Ora-1003	ENSOANG00000005371.3	F6WBV1
10		LLPS-Ora-1041	ENSOANG00000005408.4	F6UI95
11		LLPS-Ora-1139	ENSOANG00000004840.2	F7DTY8
12		LLPS-Ora-1267	ENSOANG00000012444.3	F7DA86
13		LLPS-Ora-1273	ENSOANG00000013313.3	F7EE19
14		LLPS-Ora-1326	ENSOANG00000011709.3	F6Z9B2
15		LLPS-Ora-1472	ENSOANG00000009017.3	F7EU98
16		LLPS-Ora-1805	ENSOANG00000002985.2	F6U781
17		LLPS-Ora-1907	ENSOANG00000021170.2	F7EYX7
18		LLPS-Ora-1908	ENSOANG00000012989.3	F6U064
19		LLPS-Ora-2219	ENSOANG00000011557.3	F7AVM5
20		LLPS-Ora-2273	ENSOANG00000003349.3	F6VBF3
21		LLPS-Ora-2740	ENSOANG00000020601.2	F7GEA9
22		LLPS-Ora-2774	ENSOANG00000029241.1	K7EA44
23		LLPS-Ora-2940	ENSOANG00000013849.3	F7FUH4
24		LLPS-Ora-3092	ENSOANG00000004583.1	F7DVZ4
25		LLPS-Ora-1431	ENSOANG00000007125.2	F6QQV2	AGO2
26		LLPS-Ora-3426	ENSOANG00000005875.1	F6W3I5	AK2
27		LLPS-Ora-3317	ENSOANG00000004796.3	F7FFP9	ATXN2
28		LLPS-Ora-0821	ENSOANG00000011911.3	F6S2E1	AURKA
29		LLPS-Ora-1160	ENSOANG00000000337.2	F7E7W4	C9orf72
30		LLPS-Ora-2365	ENSOANG00000004199.2	F6T174	CBX1
31		LLPS-Ora-1773	ENSOANG00000005843.4	F6XWU2	CCNT1
32		LLPS-Ora-1736	ENSOANG00000001543.2	F7D1B6	CDK7
33		LLPS-Ora-1338	ENSOANG00000008397.2	F6XLQ3	CDK9
34		LLPS-Ora-2785	ENSOANG00000012230.2	F7FGU1	CIRBP
35		LLPS-Ora-3339	ENSOANG00000011959.4	F7BIU5	DAB2IP
36		LLPS-Ora-1067	ENSOANG00000014632.2	F7E9D0	DAZAP1
37		LLPS-Ora-0819	ENSOANG00000011141.2	F7DGB0	DCP2
38		LLPS-Ora-0164	ENSOANG00000003751.2	F7CTF9	DDX6
39		LLPS-Ora-0632	ENSOANG00000006412.4	F6WIF6	DYRK1A
40		LLPS-Ora-2696	ENSOANG00000004746.2	F7G0J0	ESRP1
41		LLPS-Ora-2576	ENSOANG00000001304.4	F7FR65	EWSR1
42		LLPS-Ora-2623	ENSOANG00000011016.2	F7D6Q6	FLNA
43		LLPS-Ora-2035	ENSOANG00000001097.3	F6XJ49	FMR1
44		LLPS-Ora-3078	ENSOANG00000005606.4	F7BAJ3	FUS
45		LLPS-Ora-0511	ENSOANG00000012162.3	F7DLX2	FYN
46		LLPS-Ora-0612	ENSOANG00000003665.3	F7EBI8	GAR1
47		LLPS-Ora-0986	ENSOANG00000002057.3	F7ANI9	GNL2
48		LLPS-Ora-0807	ENSOANG00000009409.3	F6QN67	GSPT1
49		LLPS-Ora-0347	ENSOANG00000012169.2	F7DD40	HNRNPA0
50		LLPS-Ora-1226	ENSOANG00000009159.4	F7EJK5	HNRNPA2B1
51		LLPS-Ora-1911	ENSOANG00000001932.3	F6Z5S3	HNRNPD
52		LLPS-Ora-1562	ENSOANG00000004651.2	F7FH44	HNRNPDL
53		LLPS-Ora-3236	ENSOANG00000002260.3	F6RY38	HNRNPH3
54		LLPS-Ora-0313	ENSOANG00000005460.3	F7BCC2	IPO5
55		LLPS-Ora-1536	ENSOANG00000002436.3	F6ZR69	ITSN1
56		LLPS-Ora-0355	ENSOANG00000008048.3	F6RK29	KPNA2
57		LLPS-Ora-1571	ENSOANG00000001469.3	F7BST1	LBR
58		LLPS-Ora-0843	ENSOANG00000001898.4	F7AQI3	LGALS3
59		LLPS-Ora-0940	ENSOANG00000005173.3	F6R210	LOC100082962
60		LLPS-Ora-0137	ENSOANG00000007434.3	F6XTR8	LSM4
61		LLPS-Ora-1578	ENSOANG00000005945.1	F7CJ99	LYZ
62		LLPS-Ora-2349	ENSOANG00000011546.2	F6RC65	MAP1LC3A
63		LLPS-Ora-3272	ENSOANG00000006036.2	F6QLE6	MASTL
64		LLPS-Ora-2520	ENSOANG00000000608.2	F7F3L2	NCK1
65		LLPS-Ora-0336	ENSOANG00000007792.1	F6YUC7	NPM1
66		LLPS-Ora-0009	ENSOANG00000011858.4	F7EUV5	NUP153
67		LLPS-Ora-1642	ENSOANG00000014101.2	F6VNK5	NUP62
68		LLPS-Ora-1046	ENSOANG00000010001.3	F6ZQ23	PABPC4
69		LLPS-Ora-1428	ENSOANG00000007668.3	F6W916	PLK1
70		LLPS-Ora-0803	ENSOANG00000004087.3	F6YST6	PRKAA1
71		LLPS-Ora-0361	ENSOANG00000009191.2	F7CZT7	PTBP1
72		LLPS-Ora-1277	ENSOANG00000002379.2	F6SR19	RBFOX1
73		LLPS-Ora-2514	ENSOANG00000009558.2	F6S1W8	RPL23A
74		LLPS-Ora-0460	ENSOANG00000004669.2	F7FG88	RPL5
75		LLPS-Ora-3320	ENSOANG00000014976.3	F7BWW9	SOS1
76		LLPS-Ora-2870	ENSOANG00000014851.2	F7BXQ2	SQSTM1
77		LLPS-Ora-1303	ENSOANG00000014273.3	F6VK32	TAF15
78		LLPS-Ora-1814	ENSOANG00000013320.2	F7EDX1	TARDBP
79		LLPS-Ora-0476	ENSOANG00000004896.3	F7FU50	TIAL1
80		LLPS-Ora-1410	ENSOANG00000015785.4	F7FXJ5	TNPO1
81		LLPS-Ora-3305	ENSOANG00000014668.4	F6RXT0	TNRC6B
82		LLPS-Ora-0959	ENSOANG00000007702.3	F6UF81	TUBA1B
83		LLPS-Ora-0589	ENSOANG00000012417.3	F7DTN5	XPO1
84		LLPS-Ora-2503	ENSOANG00000011104.2	F7FCD0	ZNF207