Felis catus      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Fec-1933
ENSFCAG00000012430.5
A0A2I2U0F4
ATM
2
LLPS-Fec-4262
ENSFCAG00000004979.4
M3W385
ATMIN
3
LLPS-Fec-1666
ENSFCAG00000018078.4
M3WP01
ATR
4
LLPS-Fec-0327
ENSFCAG00000027928.3
M3X5Q2
FUS
5
LLPS-Fec-0990
ENSFCAG00000012483.5
A0A2I2UTS8
HDAC1
6
LLPS-Fec-1175
ENSFCAG00000007696.5
M3W867
MDC1
7
LLPS-Fec-1864
ENSFCAG00000011374.5
A0A2I2UWK2
PRKDC
8
LLPS-Fec-4292
ENSFCAG00000018829.4
M3WPH7
RAD50
9
LLPS-Fec-2852
ENSFCAG00000014712.5
M3WL72
RAD51
10
LLPS-Fec-4311
ENSFCAG00000018793.4
A0A2I2U125
RBM45
11
LLPS-Fec-2973
ENSFCAG00000022265.3
M3WYM9
TP53BP1