LLPS-Fec-1175
MDC1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Uncharacterized protein |
| Gene Name: | MDC1 |
| Ensembl Gene: | ENSFCAG00000007696.5 |
| Ensembl Protein: | ENSFCAP00000045050.1 |
| Organism: | Felis catus |
| Taxa ID: | 9685 |
| LLPS Type: | Regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| DNA damage foci, OPT domain | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSFCAT00000056455.1 | ENSFCAP00000045050.1 |
| Ensembl | ENSFCAT00000007698.5 | ENSFCAP00000007127.5 |
| UniProt | M3W867, M3W867_FELCA | |
| GeneBank | AANG04003411 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MEDTQAINWE VEEEEEKEIP SESLGCSLEP VGRLHIFSSA HGPEKDFPLY LGKNMVGRMP 60 61 DCSVILPFSS ISKQHAVIEI LAWDKAPVLQ DCGSLNGTQV LRPPKVLSPG VSHRLRDQEL 120 121 ILFADLPCQY HRLNVPLAFV SRGPLTIEET PRVQGRTQPQ GLLLAEDSEE EVDSPSERCV 180 181 VKEPRTCPLA AVVPESDEEG PSPAPDGPGP PFAFNLDSDT DEEESQHPAS GEASSTARRG 240 241 STAETKQSTA MATEIQLEKN QCSVKERNND TEVERDARNG VVPLGVILER NQPAGEDSDT 300 301 DVDDESRPPG RPAVVHLERA QPSDFIDSDT DVEEEEIPAT PAVVPMKKRQ IFHGISTESP 360 361 RTHALVHLQE SPTGSDTDVG EGEIQLAVPL ERSRASVVID SNTDGEEEVL AALALAHLKE 420 421 SRATTWNRDT DLEEDRAQPV ALREQNQTST GRDSDTDMEE EGLPMEKRGT VFKGHTDKAY 480 481 SEKRQPPPQN SDLGVDKDKS SLAVHLERSQ ASATVDINIQ VKEKVPPGSA VILVEKHQVP 540 541 VVWTDQTDVE VEEGQAKLPV MHLEEAQPPS GDCETDVEGI SLAASVVADI RKSQLPAEED 600 601 AGAKRAVAVL EHKRDLEARA QGGSLVSQVE QDHLPVSRED INDLVVTGTS GESIQPQREG 660 661 AQTSIERERE PHMDRTQDSG DNHGDSEDLD LQATQCFVER DNQNLEAAQS MEDEATQAFL 720 721 VTLPQEPGPS CCSFQDTGTL DEPWEVLATQ PFCPRESEAP EPEPIVAPLD AHGSCLSTPW 780 781 TIPQGQNPGS PVHIEPLGIQ DKGMQTMEKD MGIPREAAEG VAPERGPLDR ETENLPSGEQ 840 841 EDVIGEEELT RGIQVLARDT QGQESDQKVK IASIKRNMES LNVEIEITRE IQEKEIEKQI 900 901 LAREIFERET EKLVLEREGE PNGLGVEVPE IILERGPQRG ETEKGSQDQE GQASSPTLEL 960 961 ETGTGSHQGL ASASVASGSQ SGGGEGVPMS PRRQQRGHLT CEVPPAEKAF RGDQESTDAC 1020 1021 QPPAVPEASA PHQNPLLFQS QKHPVPQPFC SSSPSSLEPI PRTRQNRNQK VPETPLPKSK 1080 1081 VRLRGSSRKT PSPVSSVALE PHTAIPTDQP LSAEPTSQVT RGRRRRSSVK TPELVVPTAP 1140 1141 ELQPSTSKDQ PVTPELTSRI TRGRTQRFSV KAPEVVVPTA PDVQPSTSKD QSVTPELISQ 1200 1201 DRTHKFVKTP ELVISTPSQL QPSTSKGQFV LTESVSGATQ GRARRSCVKT PKAIVPTAPK 1260 1261 LQPSTSKDQP VTPEPTSRVT RGRTRGSSVK IPPESTVPTA PELQPTTSKD QSVLTGATHS 1320 1321 RIPRSSVKIP ELVVPTAPEV QSSIPTDQSV TPKPTSQRRT SRSFVKTHEP TVPTAPELQP 1380 1381 TTPKGQSVTP KRKSQGRTPR SSSKTPKPVV PTVPELQAST PTDKPVTPKL TPRATRGRTQ 1440 1441 RSSVKTPEPV VPTASELQPS ISTDQPVTPE PTFRATRGRI HRSSVKIPQP IESTASDLES 1500 1501 LNPIDQLVTP KAIAEGGQGK TLRSTVSAVP VLTTHESQNP DPIGQPVPPE PIPQANCSRK 1560 1561 RRATRKHGSF TAPIVHEPHS APPEPNSRSS KNQRRAVRAV ESLRTIPEPA LAQLPEAPTH 1620 1621 ATQIQKVEAA GRSEFTPEPQ SKPSQSRKRP LATVDSPPLQ KRLQQKTVSL HKEEEDSAES 1680 1681 PRKDEVAVIP GPGKRKRDQT EEEPRGIPSH SLRRVKPNQE STAPKVLFTG VVDARGERAV 1740 1741 LALGGSLASS VAEASHLVTD RVRRTVKFLC ALGRGIPILS LDWLHQSRKA GCFLPPDEYV 1800 1801 VTDPEQEKNF GFSLRDALSR ARERRLLEGY EIHVTPGVQP PPPQMGEIIS CCGGTVLPSM 1860 1861 PRSYKPQRVV ITCSQDFSRC SIPFRVGLPI LSPEFLLTGV LKQEAKPEAF ILSTLEMSSS 1920 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGAAGACA CCCAAGCTAT TAACTGGGAG GTTGAGGAAG AGGAGGAGAA AGAGATACCC 60 61 AGTGAATCCT TGGGGTGTAG CTTGGAGCCC GTAGGACGAC TGCATATCTT CAGTAGTGCC 120 121 CATGGACCAG AAAAAGATTT CCCTCTGTAT CTCGGGAAGA ATATGGTAGG CCGAATGCCT 180 181 GATTGCTCTG TGATCCTGCC CTTTTCATCC ATCTCCAAAC AACATGCAGT GATTGAAATC 240 241 TTGGCCTGGG ACAAGGCACC TGTCCTTCAA GATTGTGGTA GCCTCAATGG TACTCAAGTC 300 301 CTAAGGCCTC CTAAGGTCCT AAGCCCAGGG GTGAGTCATC GGCTGAGGGA CCAGGAGTTG 360 361 ATTCTCTTTG CTGACTTGCC CTGCCAGTAC CATCGCCTGA ATGTTCCCCT GGCCTTTGTT 420 421 TCCCGGGGCC CTCTAACTAT AGAAGAGACA CCCAGGGTAC AGGGACGAAC TCAACCCCAG 480 481 GGACTCCTGT TGGCTGAGGA CTCAGAGGAG GAAGTAGATT CTCCTTCAGA AAGGTGTGTG 540 541 GTGAAAGAAC CAAGAACCTG CCCTCTAGCT GCAGTGGTTC CAGAGAGTGA TGAAGAGGGG 600 601 CCTTCCCCTG CCCCAGATGG CCCTGGGCCA CCTTTTGCAT TCAACCTGGA CAGTGACACA 660 661 GATGAGGAAG AAAGTCAACA TCCAGCATCA GGAGAGGCCT CCTCAACTGC CAGAAGAGGC 720 721 TCCACTGCAG AGACAAAACA GTCTACAGCT ATGGCAACTG AAATCCAGCT TGAAAAGAAT 780 781 CAGTGTTCAG TAAAAGAGAG AAACAATGAC ACAGAAGTTG AAAGGGATGC AAGGAATGGG 840 841 GTGGTCCCAC TTGGGGTGAT ACTGGAGAGG AACCAACCTG CTGGGGAAGA CAGTGACACA 900 901 GATGTGGATG ATGAGAGCAG GCCTCCAGGA AGGCCTGCTG TGGTCCATTT GGAAAGGGCT 960 961 CAGCCTTCTG ACTTCATAGA CAGTGATACT GATGTGGAAG AAGAAGAGAT CCCTGCAACC 1020 1021 CCAGCTGTAG TTCCTATGAA GAAGAGGCAA ATCTTCCATG GAATTAGTAC AGAGAGTCCT 1080 1081 CGGACACATG CCTTGGTACA TCTACAGGAG AGCCCAACTG GTAGTGATAC AGATGTGGGG 1140 1141 GAAGGTGAGA TCCAGCTGGC AGTCCCTCTA GAGAGAAGCC GAGCCTCTGT GGTGATTGAC 1200 1201 AGCAATACAG ATGGTGAGGA AGAAGTCTTA GCAGCACTCG CTTTGGCACA TCTGAAAGAG 1260 1261 AGCCGAGCCA CTACATGGAA CAGAGATACA GATTTGGAAG AGGACAGGGC CCAACCTGTG 1320 1321 GCCCTTCGGG AGCAAAACCA AACCTCTACT GGGAGAGACA GCGACACAGA CATGGAGGAG 1380 1381 GAGGGGCTCC CAATGGAAAA GAGAGGAACT GTTTTCAAGG GTCACACAGA CAAGGCATAT 1440 1441 TCAGAAAAGA GGCAACCTCC TCCCCAAAAC AGTGATCTAG GGGTGGACAA AGATAAGAGC 1500 1501 TCACTTGCGG TCCATCTGGA GAGAAGCCAA GCCTCTGCCA CAGTGGACAT CAACATACAA 1560 1561 GTGAAGGAGA AAGTCCCACC AGGGTCAGCT GTTATACTTG TGGAGAAGCA TCAGGTGCCT 1620 1621 GTGGTATGGA CAGATCAAAC AGATGTGGAA GTAGAAGAGG GCCAAGCGAA GCTGCCTGTG 1680 1681 ATGCATCTAG AGGAAGCCCA ACCTCCATCT GGGGACTGTG AGACAGATGT GGAGGGCATA 1740 1741 TCCTTAGCAG CTTCAGTGGT GGCAGATATA AGAAAGAGCC AGCTTCCAGC AGAAGAGGAT 1800 1801 GCTGGGGCAA AGAGGGCTGT AGCTGTTCTT GAGCACAAGA GAGATCTTGA GGCGAGGGCC 1860 1861 CAGGGTGGGT CACTTGTGTC ACAGGTGGAG CAGGATCACC TCCCTGTCTC AAGGGAGGAT 1920 1921 ATTAATGATC TGGTGGTCAC AGGCACTTCA GGGGAATCCA TCCAGCCACA GAGAGAGGGA 1980 1981 GCCCAGACCT CCATAGAAAG GGAGAGAGAA CCACATATGG ACAGGACCCA GGACTCTGGA 2040 2041 GACAACCACG GTGATTCTGA AGACCTGGAC CTACAGGCTA CCCAGTGCTT TGTGGAGAGA 2100 2101 GACAATCAGA ATCTGGAAGC AGCCCAGAGC ATGGAGGATG AAGCCACCCA GGCGTTTCTG 2160 2161 GTTACTCTAC CCCAAGAGCC TGGTCCTTCC TGCTGTAGCT TCCAGGATAC AGGTACCTTG 2220 2221 GATGAGCCGT GGGAGGTCTT GGCAACACAG CCATTCTGTC CAAGAGAGTC TGAGGCCCCT 2280 2281 GAGCCCGAGC CCATTGTTGC TCCTCTTGAT GCCCATGGAT CCTGCCTCTC TACACCTTGG 2340 2341 ACAATACCAC AAGGCCAAAA TCCAGGAAGC CCAGTTCACA TAGAGCCATT GGGGATTCAG 2400 2401 GACAAAGGGA TGCAGACTAT GGAGAAAGAC ATGGGGATAC CAAGAGAAGC AGCAGAGGGG 2460 2461 GTGGCCCCTG AGAGAGGACC ATTGGACAGG GAAACTGAGA ACCTGCCATC AGGAGAACAA 2520 2521 GAAGATGTGA TAGGAGAAGA AGAGTTAACC AGAGGGATAC AGGTGTTAGC TAGAGATACT 2580 2581 CAAGGACAAG AGTCTGACCA AAAGGTGAAA ATTGCAAGTA TTAAAAGAAA TATGGAGAGT 2640 2641 TTGAACGTAG AAATTGAGAT AACCAGGGAA ATACAAGAGA AAGAAATAGA AAAGCAGATT 2700 2701 CTTGCAAGAG AAATATTTGA GAGAGAAACA GAGAAATTAG TACTAGAGAG AGAGGGTGAG 2760 2761 CCAAATGGAT TAGGAGTTGA GGTACCGGAA ATAATACTGG AGAGAGGCCC ACAGAGAGGG 2820 2821 GAGACTGAGA AAGGGAGCCA GGACCAGGAA GGGCAAGCCT CCAGTCCAAC ACTAGAGCTT 2880 2881 GAAACAGGGA CAGGCAGTCA TCAGGGACTT GCTTCAGCCT CAGTAGCTTC TGGGAGCCAG 2940 2941 TCAGGTGGAG GAGAGGGAGT CCCAATGAGC CCCAGGAGGC AGCAGAGAGG CCACTTGACT 3000 3001 TGTGAGGTGC CACCTGCTGA GAAGGCCTTC AGGGGTGATC AGGAATCTAC AGATGCTTGT 3060 3061 CAGCCTCCTG CAGTGCCTGA AGCTTCAGCC CCACACCAAA ACCCCCTCCT CTTTCAGAGT 3120 3121 CAAAAACATC CTGTGCCTCA GCCCTTCTGT TCTTCCTCTC CATCTTCTTT AGAGCCCATT 3180 3181 CCCAGGACCA GGCAAAACAG GAATCAGAAA GTTCCAGAGA CTCCCTTGCC AAAATCCAAA 3240 3241 GTCAGGCTCC GAGGGTCCTC CAGGAAGACA CCCTCTCCAG TTTCTTCTGT AGCCCTTGAA 3300 3301 CCTCATACTG CCATTCCCAC AGACCAACCC CTCAGTGCTG AGCCCACATC TCAGGTCACT 3360 3361 CGGGGCAGGA GACGTAGGTC CTCTGTGAAG ACCCCTGAAC TGGTTGTCCC CACAGCCCCT 3420 3421 GAGCTCCAGC CTTCCACTTC CAAAGACCAG CCTGTCACCC CTGAGCTCAC ATCGCGGATC 3480 3481 ACTCGGGGTA GGACACAAAG GTTCTCTGTC AAGGCCCCTG AAGTAGTTGT CCCTACAGCC 3540 3541 CCTGATGTTC AGCCTTCCAC CTCTAAAGAC CAGTCTGTCA CTCCTGAGCT CATATCTCAG 3600 3601 GACAGGACAC ATAAATTTGT AAAAACCCCT GAACTGGTTA TTTCCACACC CTCTCAGCTC 3660 3661 CAGCCTTCCA CCTCCAAAGG CCAGTTTGTC CTCACTGAGT CTGTATCTGG GGCTACTCAG 3720 3721 GGCAGGGCAC GTAGGTCTTG TGTCAAGACT CCCAAAGCAA TTGTCCCCAC AGCCCCTAAG 3780 3781 CTCCAGCCTT CTACTTCCAA AGACCAGCCT GTCACCCCTG AGCCCACATC TCGAGTCACT 3840 3841 CGAGGCAGGA CACGTGGGTC CTCTGTCAAG ATCCCTCCTG AATCAACTGT CCCCACGGCC 3900 3901 CCTGAACTCC AGCCTACCAC CTCCAAAGAC CAGTCTGTCC TCACTGGGGC CACTCATAGC 3960 3961 AGGATACCTA GGTCTTCTGT CAAGATTCCT GAGCTAGTTG TCCCAACAGC TCCTGAAGTC 4020 4021 CAGTCTTCCA TCCCCACAGA CCAGTCTGTC ACCCCCAAAC CTACATCTCA GCGCAGGACA 4080 4081 TCCAGGTCTT TTGTCAAGAC CCATGAACCA ACTGTTCCCA CAGCCCCTGA GCTCCAACCT 4140 4141 ACCACCCCCA AAGGCCAGTC TGTCACCCCC AAACGTAAAT CTCAGGGCAG GACACCCAGG 4200 4201 TCTTCTAGCA AGACCCCCAA ACCAGTTGTC CCCACAGTCC CTGAGCTCCA GGCTTCCACC 4260 4261 CCCACAGACA AGCCTGTCAC TCCCAAACTC ACACCTCGGG CCACTCGGGG CAGGACACAA 4320 4321 AGGTCCTCGG TCAAGACCCC TGAGCCAGTT GTCCCCACAG CCTCTGAGCT CCAGCCTTCC 4380 4381 ATCTCCACAG ATCAGCCTGT CACCCCTGAG CCTACATTTC GGGCCACTCG GGGAAGGATA 4440 4441 CATAGGTCCT CTGTCAAGAT CCCCCAACCA ATTGAATCTA CAGCCTCTGA CCTTGAATCT 4500 4501 CTCAACCCCA TAGATCAATT GGTCACCCCT AAGGCTATAG CTGAGGGTGG TCAGGGTAAG 4560 4561 ACACTAAGGT CTACAGTAAG TGCTGTACCA GTTCTTACCA CCCATGAATC CCAGAATCCT 4620 4621 GACCCCATAG GCCAGCCTGT TCCCCCTGAG CCCATCCCTC AAGCCAACTG CAGCAGGAAG 4680 4681 CGGAGGGCCA CAAGGAAGCA TGGGTCCTTC ACAGCTCCCA TTGTCCATGA GCCCCATTCT 4740 4741 GCACCTCCTG AACCTAACTC TCGATCCTCA AAGAACCAAA GACGAGCAGT GAGAGCAGTG 4800 4801 GAGTCTCTTA GGACCATTCC CGAGCCTGCT CTTGCCCAGC TTCCTGAGGC CCCCACTCAT 4860 4861 GCTACCCAGA TCCAAAAGGT AGAGGCAGCA GGCAGATCTG AGTTCACCCC AGAGCCCCAG 4920 4921 TCTAAGCCCT CTCAGAGCCG CAAGAGGCCT TTGGCTACTG TGGATTCACC CCCACTTCAA 4980 4981 AAACGGCTCC AACAGAAGAC CGTGTCCCTC CACAAAGAGG AAGAAGATTC AGCAGAGAGC 5040 5041 CCAAGGAAGG ACGAGGTGGC AGTGATTCCA GGACCAGGCA AGAGAAAGAG AGACCAAACA 5100 5101 GAGGAGGAGC CCAGGGGAAT CCCAAGCCAC AGCCTTCGGC GGGTCAAACC TAACCAAGAG 5160 5161 TCCACAGCAC CCAAAGTACT CTTCACAGGT GTGGTGGATG CCCGTGGAGA ACGGGCGGTG 5220 5221 CTGGCCCTGG GTGGGAGTCT GGCCAGCTCA GTGGCAGAGG CTTCCCACCT GGTGACTGAT 5280 5281 CGAGTCCGCC GCACGGTCAA GTTCCTGTGT GCCCTGGGGC GGGGGATCCC CATCCTCTCC 5340 5341 CTGGACTGGC TGCACCAGTC CCGCAAGGCT GGTTGCTTCT TGCCCCCGGA TGAATATGTG 5400 5401 GTGACTGATC CTGAGCAGGA GAAGAACTTT GGCTTCAGCC TTCGAGATGC CCTGAGCCGG 5460 5461 GCTCGGGAGA GAAGGTTGCT AGAGGGCTAT GAGATCCATG TGACCCCAGG AGTCCAGCCA 5520 5521 CCACCACCTC AAATGGGAGA GATCATCAGC TGCTGTGGAG GCACTGTCCT ACCCAGCATG 5580 5581 CCCCGCTCCT ATAAGCCTCA GAGAGTTGTG ATTACATGCT CCCAGGACTT CTCTCGATGC 5640 5641 TCTATTCCAT TTCGGGTTGG GCTGCCCATT CTCTCACCTG AGTTCCTGCT GACAGGAGTG 5700 5701 CTGAAGCAGG AAGCCAAGCC AGAGGCCTTC ATCCTCTCCA CTTTGGAAAT GTCATCCTCG 5760 5761 TGA 5763 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Urm-1618 | Ursus maritimus | 78.4 | 0.0 | 2554 |
| LLPS-Caf-3846 | Canis familiaris | 74.04 | 0.0 | 2362 |
| LLPS-Eqc-3787 | Equus caballus | 69.45 | 0.0 | 2250 |
| LLPS-Loa-4478 | Loxodonta africana | 68.69 | 1e-134 | 468 |
| LLPS-Hos-1854 | Homo sapiens | 67.23 | 0.0 | 910 |
| LLPS-Pat-4050 | Pan troglodytes | 67.15 | 0.0 | 905 |
| LLPS-Maf-3383 | Macaca fascicularis | 66.9 | 0.0 | 899 |
| LLPS-Caj-4217 | Callithrix jacchus | 66.17 | 0.0 | 870 |
| LLPS-Man-1502 | Macaca nemestrina | 66.03 | 0.0 | 2051 |
| LLPS-Paa-0117 | Papio anubis | 65.86 | 0.0 | 885 |
| LLPS-Poa-4281 | Pongo abelii | 65.56 | 0.0 | 984 |
| LLPS-Rhb-3998 | Rhinopithecus bieti | 65.42 | 0.0 | 879 |
| LLPS-Mal-4733 | Mandrillus leucophaeus | 65.29 | 0.0 | 769 |
| LLPS-Ova-3628 | Ovis aries | 64.07 | 0.0 | 1927 |
| LLPS-Mam-1159 | Macaca mulatta | 62.86 | 0.0 | 1975 |
| LLPS-Otg-3536 | Otolemur garnettii | 62.07 | 0.0 | 1830 |
| LLPS-Scm-0148 | Scophthalmus maximus | 54.55 | 4e-56 | 221 |
| LLPS-Dar-3633 | Danio rerio | 52.0 | 9e-55 | 216 |
| LLPS-Scf-3651 | Scleropages formosus | 45.97 | 3e-50 | 201 |