Xenopus tropicalis      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 79 genes.  Reviewed (0 or Unreviewed (79

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Xet-0826
ENSXETG00000030437.1
F6SWY5
2
LLPS-Xet-1016
ENSXETG00000030218.1
F7E7Z7
3
LLPS-Xet-1400
ENSXETG00000033590.1
F6R8B3
4
LLPS-Xet-1800
ENSXETG00000034020.1
F6Y4L0
5
LLPS-Xet-2432
ENSXETG00000023799.3
F7EDL3
6
LLPS-Xet-2673
ENSXETG00000030832.1
F6Z2J6
7
LLPS-Xet-3877
ENSXETG00000029942.1
F7A4Y1
8
LLPS-Xet-3559
ENSXETG00000023755.3
Q6DJB9
ago2
9
LLPS-Xet-3314
ENSXETG00000021791.3
F7BRM5
asz1
10
LLPS-Xet-3491
ENSXETG00000024395.3
Q5CZI8
casc3
11
LLPS-Xet-2781
ENSXETG00000011877.3
F6ZRD0
cd74
12
LLPS-Xet-1361
ENSXETG00000006717.3
F7B6L4
cenpv
13
LLPS-Xet-0962
ENSXETG00000025147.2
F6UEQ2
cnbp
14
LLPS-Xet-0613
ENSXETG00000034371.1
Q5G7I8
cox1
15
LLPS-Xet-2710
ENSXETG00000000671.3
F6QCK2
ctsb
16
LLPS-Xet-0562
ENSXETG00000008472.3
Q640U4
cycs
17
LLPS-Xet-0484
ENSXETG00000015662.3
F7BGM2
dcp1a
18
LLPS-Xet-1926
ENSXETG00000017825.3
Q5XH91
ddx1
19
LLPS-Xet-0034
ENSXETG00000012580.2
Q6P4W2
ddx5
20
LLPS-Xet-0276
ENSXETG00000012515.3
F7DIT1
dhx9
21
LLPS-Xet-0232
ENSXETG00000023315.3
B3DLA6
dicer1
22
LLPS-Xet-1039
ENSXETG00000005809.3
F6UYC3
edc4
23
LLPS-Xet-1247
ENSXETG00000001182.3
A9UMS0
eef1a1
24
LLPS-Xet-1363
ENSXETG00000020123.3
Q5XGH1
eif4a1
25
LLPS-Xet-0157
ENSXETG00000013720.3
B7ZTW1
eif4a3
26
LLPS-Xet-0715
ENSXETG00000009316.3
F6ZT05
eif4e
27
LLPS-Xet-2131
ENSXETG00000008752.3
Q6GLB5
elavl1
28
LLPS-Xet-3535
ENSXETG00000014319.3
B0BM20
eno4
29
LLPS-Xet-2303
ENSXETG00000024796.2
Q6P3N0
ewsr1
30
LLPS-Xet-3022
ENSXETG00000027257.1
F6TUL6
gpx4
31
LLPS-Xet-1157
ENSXETG00000012170.3
F6TA26
hnrnpa2b1
32
LLPS-Xet-2648
ENSXETG00000023026.2
Q640A2
hnrnpdl
33
LLPS-Xet-0392
ENSXETG00000018321.3
F6SEM4
hnrnph1
34
LLPS-Xet-3714
ENSXETG00000001777.4
F7C3Q6
hnrnpm
35
LLPS-Xet-1983
ENSXETG00000011386.3
F6RU04
hnrnpu
36
LLPS-Xet-3227
ENSXETG00000010251.3
F6SX68
hsp90aa1.1
37
LLPS-Xet-0387
ENSXETG00000010896.3
Q5BL42
hsp90ab1
38
LLPS-Xet-0801
ENSXETG00000022536.2
F7BBI7
hspa2
39
LLPS-Xet-2985
ENSXETG00000011651.3
Q6GL57
ilf3
40
LLPS-Xet-0337
ENSXETG00000005246.3
F6VEI6
khdrbs1
41
LLPS-Xet-0553
ENSXETG00000001958.3
F7CAL9
lamp1
42
LLPS-Xet-1260
ENSXETG00000016038.3
F6S272
lyar
43
LLPS-Xet-1397
ENSXETG00000027834.2
Q08D62
mael
44
LLPS-Xet-0741
ENSXETG00000009517.3
F6WH95
ncl
45
LLPS-Xet-3121
ENSXETG00000021683.3
F6WQ27
nedd1
46
LLPS-Xet-1894
ENSXETG00000006635.3
F6ZZL4
pabpc1
47
LLPS-Xet-0956
ENSXETG00000010533.3
A8KBF3
piwil2
48
LLPS-Xet-3088
ENSXETG00000012572.3
A0A1B8XZR1
piwil3
49
LLPS-Xet-0442
ENSXETG00000023106.3
F6U982
pmpcb
50
LLPS-Xet-0170
ENSXETG00000003303.3
F6TAG8
psip1
51
LLPS-Xet-0467
ENSXETG00000002271.2
Q28FM1
ranbp9
52
LLPS-Xet-0148
ENSXETG00000026650.2
F6Z268
rbm14
53
LLPS-Xet-1985
ENSXETG00000027956.2
Q28BZ1
rbm8a
54
LLPS-Xet-1018
ENSXETG00000001178.3
F6USY3
rpl11
55
LLPS-Xet-0127
ENSXETG00000026189.2
Q6DEP9
rpl23a
56
LLPS-Xet-1847
ENSXETG00000008052.2
F6TE47
rpl24
57
LLPS-Xet-0877
ENSXETG00000015815.3
A4IGS7
rps14
58
LLPS-Xet-1586
ENSXETG00000013596.3
F6ZD50
rps8
59
LLPS-Xet-1344
ENSXETG00000008954.3
Q6DII2
srsf1
60
LLPS-Xet-0782
ENSXETG00000001701.3
Q6DF01
srsf3
61
LLPS-Xet-3397
ENSXETG00000007400.3
F6SCF9
stk31
62
LLPS-Xet-3304
ENSXETG00000007137.3
F7DQ75
tdrd15
63
LLPS-Xet-1494
ENSXETG00000012815.3
Q6P1U3
tdrd3
64
LLPS-Xet-0709
ENSXETG00000010171.3
Q5M7P8
tdrd7
65
LLPS-Xet-3524
ENSXETG00000023069.3
F7C9C3
tdrd9
66
LLPS-Xet-2500
ENSXETG00000004373.3
Q68EP8
tekt2
67
LLPS-Xet-1325
ENSXETG00000016064.3
F6WAW3
tekt4
68
LLPS-Xet-0331
ENSXETG00000000626.2
Q28DR4
TGas006m08.1
69
LLPS-Xet-1298
ENSXETG00000016812.3
F6ZF74
tnpo1
70
LLPS-Xet-1021
ENSXETG00000018565.3
F7ES60
top3b
71
LLPS-Xet-0645
ENSXETG00000007511.3
Q6DES6
tra2b
72
LLPS-Xet-0816
ENSXETG00000020844.3
F6VQ95
ttc21b
73
LLPS-Xet-2893
ENSXETG00000027099.2
Q6GL38
ubtd1
74
LLPS-Xet-3579
ENSXETG00000013602.3
F6VP39
upf1
75
LLPS-Xet-0254
ENSXETG00000015489.3
F6Z9E5
usp9x
76
LLPS-Xet-1287
ENSXETG00000007462.3
Q5M8K3
vim
77
LLPS-Xet-2748
ENSXETG00000008848.3
Q28HT6
vps26a
78
LLPS-Xet-0714
ENSXETG00000003889.3
F6UDI3
vps35
79
LLPS-Xet-0845
ENSXETG00000021517.3
F6TPR8
ythdc2