Tursiops truncatus      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 48 genes.  Reviewed (0 or Unreviewed (48

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Tut-0404
ENSTTRG00000010786.1
2
LLPS-Tut-0616
ENSTTRG00000012830.1
3
LLPS-Tut-0652
ENSTTRG00000007310.1
4
LLPS-Tut-0804
ENSTTRG00000014138.1
5
LLPS-Tut-0897
ENSTTRG00000005120.1
6
LLPS-Tut-2268
ENSTTRG00000005014.1
7
LLPS-Tut-1219
ENSTTRG00000010867.1
A0A2U4ARP8
ADAD1
8
LLPS-Tut-2049
ENSTTRG00000010423.1
A0A2U4C0P4
AKAP4
9
LLPS-Tut-0697
ENSTTRG00000010970.1
A0A2U4B091
ASZ1
10
LLPS-Tut-2498
ENSTTRG00000013031.1
A0A2U4AHQ9
CD74
11
LLPS-Tut-0542
ENSTTRG00000015266.1
A0A2U3V030
CNBP
12
LLPS-Tut-1906
ENSTTRG00000025390.1
B9UD78
COI
13
LLPS-Tut-2200
ENSTTRG00000011972.1
A0A2U4B3Y5
CTSB
14
LLPS-Tut-0271
ENSTTRG00000005081.1
A0A2U4C066
DDX1
15
LLPS-Tut-1728
ENSTTRG00000008793.1
A0A2U4C0L6
DDX17
16
LLPS-Tut-1083
ENSTTRG00000000114.1
A0A2U4AUM0
EEF1A1
17
LLPS-Tut-0392
ENSTTRG00000004206.1
A0A2U4AM14
EIF4E
18
LLPS-Tut-0204
ENSTTRG00000014891.1
A0A2U3V7S8
GPX7
19
LLPS-Tut-0197
ENSTTRG00000000709.1
A0A2U4AMA3
HNRNPA2B1
20
LLPS-Tut-0888
ENSTTRG00000014225.1
A0A2U4AAR0
HNRNPA3
21
LLPS-Tut-0879
ENSTTRG00000002756.1
A0A2U4B2D9
IP6K1
22
LLPS-Tut-0144
ENSTTRG00000009637.1
A0A2U3V478
KHDRBS1
23
LLPS-Tut-1267
ENSTTRG00000004460.1
A0A2U4A6B1
LAMP1
24
LLPS-Tut-0831
ENSTTRG00000013756.1
C6L2F0
LDHA
25
LLPS-Tut-1835
ENSTTRG00000002958.1
A0A2U3V834
LOC101321546
26
LLPS-Tut-1840
ENSTTRG00000013450.1
A0A2U4C510
LOC101324316
27
LLPS-Tut-0131
ENSTTRG00000005612.1
A0A2U4CC46
LOC109552138
28
LLPS-Tut-0826
ENSTTRG00000012812.1
A0A2U4ATE0
LYAR
29
LLPS-Tut-1797
ENSTTRG00000009094.1
A0A2U3V9F5
NCL
30
LLPS-Tut-0626
ENSTTRG00000000382.1
A0A2U3V5C2
ODF1
31
LLPS-Tut-0583
ENSTTRG00000016994.1
A0A2U3V9L6
PIWIL1
32
LLPS-Tut-1432
ENSTTRG00000010699.1
A0A2U4BSN0
PMPCB
33
LLPS-Tut-0645
ENSTTRG00000007813.1
A0A2U4C5B4
RANBP9
34
LLPS-Tut-0123
ENSTTRG00000009081.1
A0A2U4A315
RBM8A
35
LLPS-Tut-0965
ENSTTRG00000010670.1
A0A2U3V9U4
RNASE6
36
LLPS-Tut-0410
ENSTTRG00000016115.1
A0A2U4BJ64
RPL11
37
LLPS-Tut-0511
ENSTTRG00000002851.1
A0A2U3V0M4
RPL24
38
LLPS-Tut-1554
ENSTTRG00000013035.1
A0A2U4AHH7
RPS14
39
LLPS-Tut-0622
ENSTTRG00000003388.1
A0A2U3V6E6
RPS8
40
LLPS-Tut-0927
ENSTTRG00000015605.1
A0A2U4BFJ0
SPERT
41
LLPS-Tut-1488
ENSTTRG00000013447.1
A0A2U3UZ23
SRSF3
42
LLPS-Tut-0925
ENSTTRG00000007619.1
A0A2U4C1X2
TOMM34
43
LLPS-Tut-0629
ENSTTRG00000008243.1
A0A2U4C8J3
TRA2B
44
LLPS-Tut-0791
ENSTTRG00000009894.1
A0A2U4BQ11
UBTD1
45
LLPS-Tut-1558
ENSTTRG00000013867.1
A0A2U4C0S9
USP9X
46
LLPS-Tut-0000
ENSTTRG00000000436.1
A0A2U3V0C3
VIM
47
LLPS-Tut-2041
ENSTTRG00000008175.1
A0A2U3V6X5
VPS26A
48
LLPS-Tut-2184
ENSTTRG00000013280.1
A0A2U4B4L7
VPS35