Rattus norvegicus      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 105 genes.  Reviewed (26 or Unreviewed (79

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ran-0018
ENSRNOG00000046144.1
Q6LED0
2
LLPS-Ran-0027
ENSRNOG00000017164.8
M0R484
Afap1l2
3
LLPS-Ran-0015
ENSRNOG00000018735.7
P10247
Cd74
4
LLPS-Ran-0021
ENSRNOG00000010331.5
P00787
Ctsb
5
LLPS-Ran-0000
ENSRNOG00000010452.7
P62898
Cycs
6
LLPS-Ran-0037
ENSRNOG00000012260.4
Q9QY16
Ddx25
7
LLPS-Ran-0012
ENSRNOG00000030628.2
Q6P3V8
Eif4a1
8
LLPS-Ran-0010
ENSRNOG00000052343.3
P63074
Eif4e
9
LLPS-Ran-0038
ENSRNOG00000018310.6
D3ZRT2
Eno4
10
LLPS-Ran-0036
ENSRNOG00000013604.7
P36970
Gpx4
11
LLPS-Ran-0001
ENSRNOG00000016865.3
Q00729
Hist1h2ba
12
LLPS-Ran-0020
ENSRNOG00000032224.4
P62804
Hist4h4
13
LLPS-Ran-0004
ENSRNOG00000011175.8
A7VJC2
Hnrnpa2b1
14
LLPS-Ran-0042
ENSRNOG00000045654.2
P0DMW1
Hspa1b
15
LLPS-Ran-0026
ENSRNOG00000046794.1
Q91V33
Khdrbs1
16
LLPS-Ran-0035
ENSRNOG00000019629.7
P14562
Lamp1
17
LLPS-Ran-0006
ENSRNOG00000013009.2
P04642
Ldha
18
LLPS-Ran-0050
ENSRNOG00000034234.3
P05503
Mtco1
19
LLPS-Ran-0034
ENSRNOG00000008639.7
Q9EPH8
Pabpc1
20
LLPS-Ran-0019
ENSRNOG00000012693.5
Q03346
Pmpcb
21
LLPS-Ran-0039
ENSRNOG00000045568.3
M0R9Q1
Rbm14
22
LLPS-Ran-0051
ENSRNOG00000025597.3
Q6QDX6
Rnase6
23
LLPS-Ran-0745
ENSRNOG00000001783.6
P62997
Tra2b
24
LLPS-Ran-0031
ENSRNOG00000017209.6
Q4QRB4
Tubb3
25
LLPS-Ran-0014
ENSRNOG00000013813.6
Q68FV8
Ubtd1
26
LLPS-Ran-0048
ENSRNOG00000018087.5
P31000
Vim
27
LLPS-Ran-0768
ENSRNOG00000017246.6
Q3KR54
Adad1
28
LLPS-Ran-3758
ENSRNOG00000015690.6
F1M8B2
Adad2
29
LLPS-Ran-1814
ENSRNOG00000008533.4
Q9QZ81
Ago2
30
LLPS-Ran-2837
ENSRNOG00000060343.1
Q8VHF9
Asz1
31
LLPS-Ran-2396
ENSRNOG00000009716.4
Q8K3X0
Casc3
32
LLPS-Ran-2582
ENSRNOG00000003086.7
D4A9A3
Cenpv
33
LLPS-Ran-0113
ENSRNOG00000010239.6
P62634
Cnbp
34
LLPS-Ran-1756
ENSRNOG00000016015.5
D4AE80
Dcp1a
35
LLPS-Ran-1195
ENSRNOG00000006652.6
Q641Y8
Ddx1
36
LLPS-Ran-1686
ENSRNOG00000002501.4
D3ZN21
Ddx3y
37
LLPS-Ran-1550
ENSRNOG00000026686.6
Q64060
Ddx4
38
LLPS-Ran-1250
ENSRNOG00000030680.4
Q6AYI1
Ddx5
39
LLPS-Ran-0785
ENSRNOG00000002735.6
D4A9D6
Dhx9
40
LLPS-Ran-0203
ENSRNOG00000010711.7
E9PU15
Dicer1
41
LLPS-Ran-3370
ENSRNOG00000024025.6
Q3ZAV8
Edc4
42
LLPS-Ran-2672
ENSRNOG00000009439.6
P62630
Eef1a1
43
LLPS-Ran-3007
ENSRNOG00000045791.2
Q3B8Q2
Eif4a3
44
LLPS-Ran-2725
ENSRNOG00000001069.6
B5DF91
Elavl1
45
LLPS-Ran-0538
ENSRNOG00000009437.7
A0A140UHY3
Ewsr1
46
LLPS-Ran-2662
ENSRNOG00000011082.4
P55054
Fabp9
47
LLPS-Ran-4822
ENSRNOG00000006336.7
D3Z9D2
Fyco1
48
LLPS-Ran-4789
ENSRNOG00000052968.1
Q6URK4
Hnrnpa3
49
LLPS-Ran-3396
ENSRNOG00000002270.7
Q3SWU3
Hnrnpdl
50
LLPS-Ran-1371
ENSRNOG00000014562.6
Q794E4
Hnrnpf
51
LLPS-Ran-4425
ENSRNOG00000003399.8
Q8VHV7
Hnrnph1
52
LLPS-Ran-3398
ENSRNOG00000007921.8
Q62826
Hnrnpm
53
LLPS-Ran-1109
ENSRNOG00000033790.4
Q6IMY8
Hnrnpu
54
LLPS-Ran-2268
ENSRNOG00000007219.7
P82995
Hsp90aa1
55
LLPS-Ran-0580
ENSRNOG00000019834.6
P34058
Hsp90ab1
56
LLPS-Ran-4098
ENSRNOG00000006472.5
P14659
Hspa2
57
LLPS-Ran-2644
ENSRNOG00000009052.7
A0A0G2K0Y2
Igf2bp3
58
LLPS-Ran-1620
ENSRNOG00000022741.6
Q9JIL3
Ilf3
59
LLPS-Ran-0881
ENSRNOG00000019932.6
Q9ESM0
Ip6k1
60
LLPS-Ran-3281
ENSRNOG00000013103.6
P19629
Ldhc
61
LLPS-Ran-1016
ENSRNOG00000005374.6
Q6AYK5
Lyar
62
LLPS-Ran-1274
ENSRNOG00000003790.5
D3ZG86
Mael
63
LLPS-Ran-1423
ENSRNOG00000010316.7
F1M0X6
Magohb
64
LLPS-Ran-3319
ENSRNOG00000018273.7
P13383
Ncl
65
LLPS-Ran-3022
ENSRNOG00000004011.6
D3ZAH3
Nedd1
66
LLPS-Ran-2560
ENSRNOG00000006578.5
P21769
Odf1
67
LLPS-Ran-0464
ENSRNOG00000000934.5
D3ZTP9
Piwil1
68
LLPS-Ran-1874
ENSRNOG00000009871.4
D3ZRE1
Piwil2
69
LLPS-Ran-3809
ENSRNOG00000011498.6
Q812D1
Psip1
70
LLPS-Ran-1589
ENSRNOG00000017951.8
F1LVV3
Ranbp9
71
LLPS-Ran-0952
ENSRNOG00000004980.7
D3ZMP9
Rangrf
72
LLPS-Ran-0581
ENSRNOG00000021215.7
Q27W01
Rbm8a
73
LLPS-Ran-3461
ENSRNOG00000008059.7
D3ZLP2
Rnf17
74
LLPS-Ran-1393
ENSRNOG00000026260.6
P62914
Rpl11
75
LLPS-Ran-0783
ENSRNOG00000023344.3
P62752
Rpl23a
76
LLPS-Ran-1036
ENSRNOG00000001611.7
P83732
Rpl24
77
LLPS-Ran-1516
ENSRNOG00000018774.5
P13471
Rps14
78
LLPS-Ran-0650
ENSRNOG00000054626.1
P62243
Rps8
79
LLPS-Ran-0107
ENSRNOG00000003041.8
D4A589
Smg6
80
LLPS-Ran-3248
ENSRNOG00000047413.1
Q6AXV6
Spert
81
LLPS-Ran-1234
ENSRNOG00000050323.1
D4A9L2
Srsf1
82
LLPS-Ran-1681
ENSRNOG00000000520.8
Q0ZFS8
Srsf3
83
LLPS-Ran-1967
ENSRNOG00000057554.1
A0A0G2JWJ2
Stk31
84
LLPS-Ran-0653
ENSRNOG00000017064.5
D4A3N0
Tdrd1
85
LLPS-Ran-3060
ENSRNOG00000009034.7
Q66HC1
Tdrd3
86
LLPS-Ran-4233
ENSRNOG00000004018.7
B4F7C4
Tdrd5
87
LLPS-Ran-1308
ENSRNOG00000025693.6
D3ZXQ5
Tdrd6
88
LLPS-Ran-1825
ENSRNOG00000055779.1
Q9R1R4
Tdrd7
89
LLPS-Ran-2633
ENSRNOG00000053631.1
Q3MHU3
Tdrd9
90
LLPS-Ran-0601
ENSRNOG00000011033.4
Q6AYM2
Tekt2
91
LLPS-Ran-0076
ENSRNOG00000018792.5
Q6AXV2
Tekt4
92
LLPS-Ran-4760
ENSRNOG00000002566.5
P11101
Tnp2
93
LLPS-Ran-0484
ENSRNOG00000014999.7
F1LQP9
Tnpo1
94
LLPS-Ran-3774
ENSRNOG00000024737.6
A0A0G2JZJ3
Tnrc6a
95
LLPS-Ran-0217
ENSRNOG00000029799.4
Q3KRD5
Tomm34
96
LLPS-Ran-3289
ENSRNOG00000001845.5
D4A9Z2
Top3b
97
LLPS-Ran-2339
ENSRNOG00000020484.6
F1LMD7
Trpm5
98
LLPS-Ran-4729
ENSRNOG00000005868.7
D4A333
Ttc21b
99
LLPS-Ran-0481
ENSRNOG00000031707.2
Q68FR8
Tuba3b
100
LLPS-Ran-3751
ENSRNOG00000020134.7
A0A0U1RS25
Upf1
101
LLPS-Ran-3379
ENSRNOG00000003261.7
A0A0G2K2C7
Usp9x
102
LLPS-Ran-0834
ENSRNOG00000030683.5
Q6AY86
Vps26a
103
LLPS-Ran-4279
ENSRNOG00000017612.5
G3V8A5
Vps35
104
LLPS-Ran-2674
ENSRNOG00000017117.7
D4A3P0
Ybx2
105
LLPS-Ran-0820
ENSRNOG00000039241.4
D3ZIV8
Ythdc2