Danio rerio      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 83 genes.  Reviewed (2 or Unreviewed (81

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Dar-0002
ENSDARG00000041699.8
Q8UVX0
piwil1
2
LLPS-Dar-0007
ENSDARG00000070052.8
F1R237
tdrd6
3
LLPS-Dar-0275
ENSDARG00000038068.9
4
LLPS-Dar-2448
ENSDARG00000089181.4
F1RC56
adad1
5
LLPS-Dar-3783
ENSDARG00000105626.2
A0A1D5NSL4
adad2
6
LLPS-Dar-2379
ENSDARG00000074806.4
E7FH23
afap1l2
7
LLPS-Dar-1445
ENSDARG00000061268.6
E7EXY4
ago2
8
LLPS-Dar-2338
ENSDARG00000116151.1
A0A2R8RIS0
asz1
9
LLPS-Dar-1885
ENSDARG00000029911.7
Q1ECZ4
casc3
10
LLPS-Dar-2115
ENSDARG00000009087.11
Q9PUT2
cd74a
11
LLPS-Dar-0920
ENSDARG00000092285.3
B0R188
cenpv
12
LLPS-Dar-0436
ENSDARG00000070922.7
E7FCQ0
cnbpb
13
LLPS-Dar-3486
ENSDARG00000055120.7
Q6PH75
ctsba
14
LLPS-Dar-3137
ENSDARG00000044562.4
Q6IQM2
cyc
15
LLPS-Dar-1078
ENSDARG00000100136.3
A0A0R4IBD6
dcp1a
16
LLPS-Dar-1772
ENSDARG00000032117.11
F1R2L8
ddx1
17
LLPS-Dar-0036
ENSDARG00000014373.11
E7EZA2
ddx4
18
LLPS-Dar-0400
ENSDARG00000109655.1
Q6TV19
dicer1
19
LLPS-Dar-0513
ENSDARG00000062266.7
Q1LUT1
edc4
20
LLPS-Dar-2646
ENSDARG00000069951.6
Q92005
eef1a
21
LLPS-Dar-1037
ENSDARG00000092115.5
Q802C9
eif4a1a
22
LLPS-Dar-1229
ENSDARG00000102978.2
Q7ZVA6
eif4a3
23
LLPS-Dar-0764
ENSDARG00000013274.8
B8JIA7
eif4eb
24
LLPS-Dar-1777
ENSDARG00000038695.7
F1QM02
elavl1a
25
LLPS-Dar-3457
ENSDARG00000070598.5
Q08BC6
eno4
26
LLPS-Dar-2944
ENSDARG00000020465.10
Q4QRG0
ewsr1b
27
LLPS-Dar-1325
ENSDARG00000104500.2
A0A0R4IIH4
fyco1a
28
LLPS-Dar-4278
ENSDARG00000076836.4
A0A2R8RWH8
gpx4b
29
LLPS-Dar-2139
ENSDARG00000003429.9
Q7SXN2
hnrnpdl
30
LLPS-Dar-1241
ENSDARG00000040881.6
Q6P0V0
hnrnph1
31
LLPS-Dar-2735
ENSDARG00000061735.10
F1R2E0
hnrnpm
32
LLPS-Dar-1416
ENSDARG00000004735.12
Q5RHQ7
hnrnpub
33
LLPS-Dar-2346
ENSDARG00000055723.6
B0S610
hsp70l
34
LLPS-Dar-0776
ENSDARG00000010478.12
Q90474
hsp90a.1
35
LLPS-Dar-1009
ENSDARG00000029150.10
O57521
hsp90ab1
36
LLPS-Dar-0524
ENSDARG00000010266.9
Q9PW80
igf2bp3
37
LLPS-Dar-0529
ENSDARG00000105177.2
Q6NXA4
ilf3
38
LLPS-Dar-3549
ENSDARG00000070475.5
Q6NW62
khdrbs1b
39
LLPS-Dar-3138
ENSDARG00000100181.2
A0A0G2LAZ5
lamp1a
40
LLPS-Dar-1784
ENSDARG00000101251.2
Q9PVK5
ldha
41
LLPS-Dar-1498
ENSDARG00000098507.2
A0A0G2L833
lyar
42
LLPS-Dar-3194
ENSDARG00000063905.3
Q9MIY8
mt-co1
43
LLPS-Dar-2193
ENSDARG00000013472.10
F1QAL1
nedd1
44
LLPS-Dar-0605
ENSDARG00000021140.12
Q6P3L1
pabpc1b
45
LLPS-Dar-3337
ENSDARG00000062601.8
A2CEI6
piwil2
46
LLPS-Dar-0445
ENSDARG00000016979.8
Q1L8E2
pmpcb
47
LLPS-Dar-2861
ENSDARG00000104710.3
A0A0R4IXV5
psip1a
48
LLPS-Dar-1898
ENSDARG00000061048.6
A1L252
ranbp9
49
LLPS-Dar-2424
ENSDARG00000098786.2
A3KPP3
rangrf
50
LLPS-Dar-0499
ENSDARG00000016516.6
Q5D018
rbm8a
51
LLPS-Dar-4264
ENSDARG00000056387.8
F1R3C5
rnf17
52
LLPS-Dar-0609
ENSDARG00000043509.7
Q6IQI6
rpl11
53
LLPS-Dar-1457
ENSDARG00000006316.8
F1QGI3
rpl23a
54
LLPS-Dar-1423
ENSDARG00000099104.1
Q8JGR4
rpl24
55
LLPS-Dar-1519
ENSDARG00000036629.6
Q6PBW3
rps14
56
LLPS-Dar-0679
ENSDARG00000055996.6
P62247
rps8
57
LLPS-Dar-0155
ENSDARG00000054570.8
A0A2R8QK29
smg1
58
LLPS-Dar-0241
ENSDARG00000100481.2
A0A0R4IZ84
smg6
59
LLPS-Dar-2399
ENSDARG00000017843.12
Q6NYA0
srsf1b
60
LLPS-Dar-2826
ENSDARG00000059360.7
A5WWG4
srsf3b
61
LLPS-Dar-1096
ENSDARG00000056339.6
E7F7Y8
stk31
62
LLPS-Dar-4258
ENSDARG00000109298.1
Q58EK5
tdrd1
63
LLPS-Dar-0302
ENSDARG00000025421.10
Q6NYG6
tdrd3
64
LLPS-Dar-1536
ENSDARG00000071450.6
Q1L981
tdrd5
65
LLPS-Dar-3328
ENSDARG00000077523.4
E7FDW8
tdrd7b
66
LLPS-Dar-2125
ENSDARG00000013453.9
B8A4F4
tdrd9
67
LLPS-Dar-0333
ENSDARG00000028973.9
Q1L952
tekt2
68
LLPS-Dar-3751
ENSDARG00000028899.9
B8A4G8
tekt4
69
LLPS-Dar-0234
ENSDARG00000035390.7
F1RDR1
tnpo1
70
LLPS-Dar-3653
ENSDARG00000079688.5
A0A0R4IJ26
tnrc6a
71
LLPS-Dar-3646
ENSDARG00000001557.9
Q6ZM24
tomm34
72
LLPS-Dar-2235
ENSDARG00000027586.11
F1QNX4
top3b
73
LLPS-Dar-1272
ENSDARG00000002168.8
B0V332
tra2b
74
LLPS-Dar-4240
ENSDARG00000059792.8
Q1MTB2
trpm5
75
LLPS-Dar-3957
ENSDARG00000012368.13
B0R0W1
ttc21b
76
LLPS-Dar-2168
ENSDARG00000079623.6
Q4V8W7
ubtd1
77
LLPS-Dar-0081
ENSDARG00000016302.12
F1RCY6
upf1
78
LLPS-Dar-1208
ENSDARG00000013708.11
Q4FE55
usp9
79
LLPS-Dar-3640
ENSDARG00000010008.8
F1QAM8
vim
80
LLPS-Dar-2746
ENSDARG00000056549.5
Q6TNP8
vps26a
81
LLPS-Dar-2806
ENSDARG00000008224.11
Q6ZM34
vps35
82
LLPS-Dar-4120
ENSDARG00000103525.2
A0A0G2KIQ1
ythdc2
83
LLPS-Dar-0749
ENSDARG00000061547.5
X1WGM1
zgc:163040