Schizosaccharomyces pombe      Centrosome/Spindle pole body


※ Centrosome/Spindle pole body introduction

    A centrosome is a composite material comprising a pair of 200-nm-long barrel-shaped centrioles surrounded by a dynamic protein mass called the pericentriolar material (PCM), which organizes hundreds to thousands of microtubules that build and position the mitotic spindle in metazoans (1). The seemingly unstructured mitotic PCM provides most of the mass and microtubule nucleation capacity of the centrosome, Mitotic PCM could also be liquid like, the mitotic PCM first assembles through phase separation of SPD-5 molecules around the centrioles. Liquid–liquid phase separation of the SPD-5 scaffold followed by maturation into a gel could explain why mitotic PCM is both spherical and stable (1).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 29258725


There are 170 genes.  Reviewed (49 or Unreviewed (121

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Scp-0161
SPCC895.07
O94534
alp14
2
LLPS-Scp-0067
SPBC365.15
Q9Y705
alp4
3
LLPS-Scp-0038
SPBC428.20c
Q9USQ2
alp6
4
LLPS-Scp-0179
SPAC890.02c
Q9URY2
alp7
5
LLPS-Scp-0182
SPAC1002.06c
Q9US52
bqt2
6
LLPS-Scp-0083
SPAC222.10c
Q10951
byr4
7
LLPS-Scp-0171
SPCC188.07
Q10432
ccq1
8
LLPS-Scp-0127
SPCC1739.11c
O74473
cdc11
9
LLPS-Scp-0029
SPBC24C6.07
P36589
cdc14
10
LLPS-Scp-0108
SPAC6F6.08c
P36618
cdc16
11
LLPS-Scp-0000
SPBC21.06c
P41892
cdc7
12
LLPS-Scp-0027
SPAC1782.09c
Q9P7H1
clp1
13
LLPS-Scp-0094
SPCC5E4.04
P18296
cut1
14
LLPS-Scp-0132
SPAC1786.03
O13961
cut11
15
LLPS-Scp-0173
SPBC649.05
O59755
cut12
16
LLPS-Scp-0016
SPAC25G10.07c
P24339
cut7
17
LLPS-Scp-0100
SPCC736.14
Q09933
dis1
18
LLPS-Scp-0144
SPAC1805.08
Q9UTS6
dlc1
19
LLPS-Scp-0092
SPAC17G8.10c
Q10322
dma1
20
LLPS-Scp-0004
SPAC19E9.02
O13839
fin1
21
LLPS-Scp-0151
SPAC3A11.14c
Q92376
klp1
22
LLPS-Scp-0169
SPAC3A11.05c
P87245
kms1
23
LLPS-Scp-0186
SPBC582.06c
Q10336
mcp6
24
LLPS-Scp-0060
SPBC428.13c
O94360
mob1
25
LLPS-Scp-0041
SPCC736.06
O94242
msd1
26
LLPS-Scp-0047
SPBC30B4.06c
O13670
mto1
27
LLPS-Scp-0011
SPBC11C11.03
Q10198
ndc80
28
LLPS-Scp-0168
SPAC3G9.01
Q7LL22
nsk1
29
LLPS-Scp-0078
SPAC27F1.04c
Q10173
nuf2
30
LLPS-Scp-0033
SPCC188.02
Q10428
par1
31
LLPS-Scp-0114
SPAC6G9.06c
Q92351
pcp1
32
LLPS-Scp-0032
SPAC23C11.16
P50528
plo1
33
LLPS-Scp-0069
SPAC1834.06c
Q9P7Q8
pmo25
34
LLPS-Scp-0028
SPBC365.06
O13351
pmt3
35
LLPS-Scp-0091
SPAC4H3.11c
Q10218
ppc89
36
LLPS-Scp-0166
SPBC1778.10c
Q9Y7J6
ppk21
37
LLPS-Scp-0180
SPCC417.06c
O94487
ppk35
38
LLPS-Scp-0099
SPAC6B12.15
Q10281
rkp1
39
LLPS-Scp-0118
SPAC4F8.13c
O14188
rng2
40
LLPS-Scp-0126
SPBC11B10.05c
O13601
rsp1
41
LLPS-Scp-0034
SPBC12D12.01
Q09825
sad1
42
LLPS-Scp-0074
SPAC9G1.09
O14305
sid1
43
LLPS-Scp-0131
SPAC24B11.11c
Q09898
sid2
44
LLPS-Scp-0154
SPBC244.01c
O60187
sid4
45
LLPS-Scp-0035
SPAC23H4.04
O13947
SPAC23H4.04
46
LLPS-Scp-0143
SPBC336.08
Q9UST6
spc24
47
LLPS-Scp-0006
SPCC188.04c
Q10430
spc25
48
LLPS-Scp-0112
SPAC1565.06c
P87027
spg1
49
LLPS-Scp-0136
SPAC1F3.06c
Q10411
spo15
50
LLPS-Scp-0463
SPBC947.01
O43078
alf1
51
LLPS-Scp-0789
SPBC11C11.04c
Q10197
alp1
52
LLPS-Scp-0616
SPBC1A4.01
O42971
apc10
53
LLPS-Scp-0044
SPCC320.13c
O59790
ark1
54
LLPS-Scp-1582
SPAC1D4.13
P10506
byr1
55
LLPS-Scp-0514
SPAC3A12.14
P05933
cam1
56
LLPS-Scp-0300
SPBC12D12.03
O94501
cct1
57
LLPS-Scp-0235
SPBC582.03
P10815
cdc13
58
LLPS-Scp-0658
SPBC11B10.09
P04551
cdc2
59
LLPS-Scp-0359
SPCC1682.04
O74435
cdc31
60
LLPS-Scp-0276
SPAC110.03
Q01112
cdc42
61
LLPS-Scp-1413
SPCC18B5.11c
Q09170
cds1
62
LLPS-Scp-1535
SPAC17H9.19c
Q10990
cdt2
63
LLPS-Scp-1007
SPAC8C9.03
P36600
cgs1
64
LLPS-Scp-1171
SPCC1259.13
P34208
chk1
65
LLPS-Scp-1560
SPAC3G6.11
O14147
chl1
66
LLPS-Scp-0312
SPCC4E9.02
P24865
cig1
67
LLPS-Scp-0043
SPBC36.05c
O59702
clr6
68
LLPS-Scp-1625
SPCC830.06
Q9UU93
cnb1
69
LLPS-Scp-0882
SPBC215.03c
O94308
csn1
70
LLPS-Scp-0710
SPAC1B3.08
O13873
csn12
71
LLPS-Scp-0305
SPAPB17E12.04c
Q9HFR0
csn2
72
LLPS-Scp-1149
SPAC1687.13c
O94454
csn5
73
LLPS-Scp-1382
SPBC106.09
Q9URV2
cut4
74
LLPS-Scp-1142
SPAC6F12.15c
P41889
cut9
75
LLPS-Scp-1565
SPBC3B9.22c
Q50HP4
dad4
76
LLPS-Scp-0794
SPAC1093.06c
O13290
dhc1
77
LLPS-Scp-0875
SPBC646.17c
O94518
dic1
78
LLPS-Scp-0052
SPBC776.02c
P13681
dis2
79
LLPS-Scp-0969
SPAC1782.01
Q9P7H8
ecm29
80
LLPS-Scp-1361
SPAC15A10.16
O13735
fat1
81
LLPS-Scp-1566
SPBC106.13
Q9URU9
fyv10
82
LLPS-Scp-1194
SPBC3H7.15
P40235
hhp1
83
LLPS-Scp-0991
SPBC8D2.04
P09988
hht2
84
LLPS-Scp-0985
SPCC132.02
Q9USN7
hst2
85
LLPS-Scp-0864
SPCC1442.17c
O74490
ist1
86
LLPS-Scp-0125
SPAC664.10
Q9US03
klp2
87
LLPS-Scp-0081
SPBC2F12.13
O14343
klp5
88
LLPS-Scp-0541
SPBC15D4.01c
Q1MTQ7
klp9
89
LLPS-Scp-0902
SPBC23G7.12c
P41836
let1
90
LLPS-Scp-0037
SPBC3D6.04c
P87169
mad1
91
LLPS-Scp-0066
SPBC20F10.06
O14417
mad2
92
LLPS-Scp-0377
SPBC4.04c
P40377
mcm2
93
LLPS-Scp-0679
SPCC1682.02c
P30666
mcm3
94
LLPS-Scp-0314
SPCC16A11.17
P29458
mcm4
95
LLPS-Scp-0385
SPAC1B2.05
P41389
mcm5
96
LLPS-Scp-0693
SPBC211.04c
P49731
mcm6
97
LLPS-Scp-0701
SPBC25D12.03c
O75001
mcm7
98
LLPS-Scp-0990
SPBC1198.12
O94423
mfr1
99
LLPS-Scp-0133
SPBC409.04c
Q9Y738
mis12
100
LLPS-Scp-1297
SPCC970.04c
O74558
mob2
101
LLPS-Scp-0571
SPBC106.01
O94235
mph1
102
LLPS-Scp-0315
SPAC15A10.05c
O13725
mug182
103
LLPS-Scp-0862
SPBC16A3.15c
P04688
nda2
104
LLPS-Scp-1042
SPBC26H8.07c
P05219
nda3
105
LLPS-Scp-0002
SPAC29E6.04
Q09858
nnf1
106
LLPS-Scp-1220
SPAC17C9.01c
P10505
nuc2
107
LLPS-Scp-1081
SPBC29A10.15
P54789
orc1
108
LLPS-Scp-0957
SPBC685.09
Q09142
orc2
109
LLPS-Scp-1328
SPAC3H1.01c
Q10067
orc3
110
LLPS-Scp-1546
SPBP23A10.13
Q9Y794
orc4
111
LLPS-Scp-1467
SPBC646.14c
O43114
orc5
112
LLPS-Scp-0718
SPAP8A3.09c
Q9UT08
paa1
113
LLPS-Scp-1638
SPAC3G9.12
O42874
peg1
114
LLPS-Scp-0615
SPCC16C4.03
O74448
pin1
115
LLPS-Scp-0277
SPCC126.02c
O94395
pku70
116
LLPS-Scp-0020
SPBC543.03c
Q9HGM8
pku80
117
LLPS-Scp-0807
SPAC2F7.16c
Q09706
pld1
118
LLPS-Scp-1484
SPAC4D7.03
O14170
pop2
119
LLPS-Scp-0927
SPBC18H10.15
O60145
ppk23
120
LLPS-Scp-1384
SPAC15A10.13
O13733
ppk3
121
LLPS-Scp-1335
SPBC29A10.04
O94383
psm1
122
LLPS-Scp-0582
SPAC10F6.09c
O42649
psm3
123
LLPS-Scp-0654
SPBC609.02
O94526
ptn1
124
LLPS-Scp-0104
SPAC11G7.02
Q92462
pub1
125
LLPS-Scp-0414
SPAC8E11.02c
P42656
rad24
126
LLPS-Scp-0890
SPAC20H4.11c
Q9HE04
rho5
127
LLPS-Scp-0762
SPBP19A11.03c
P87048
rpn1
128
LLPS-Scp-0285
SPAC637.10c
O94444
rpn10
129
LLPS-Scp-1209
SPBC17D11.07c
O74762
rpn2
130
LLPS-Scp-0800
SPBC119.01
O42897
rpn3
131
LLPS-Scp-0233
SPAPB8E5.09
Q9C0X6
rvb1
132
LLPS-Scp-0245
SPBC83.08
O94692
rvb2
133
LLPS-Scp-1217
SPBC1773.07c
Q09717
sbp1
134
LLPS-Scp-0019
SPCC31H12.05c
P23880
sds21
135
LLPS-Scp-1277
SPBC409.05
Q9Y709
skp1
136
LLPS-Scp-0049
SPAC821.08c
P78972
slp1
137
LLPS-Scp-1653
SPAC1805.16c
Q9UTG1
SPAC1805.16c
138
LLPS-Scp-1235
SPAC27E2.03c
O13998
SPAC27E2.03c
139
LLPS-Scp-1327
SPAC328.04
Q9P3U2
SPAC328.04
140
LLPS-Scp-1031
SPAC664.03
Q9US06
SPAC664.03
141
LLPS-Scp-1580
SPBC25H2.03
P87145
SPBC25H2.03
142
LLPS-Scp-1645
SPBC25H2.15
P87156
SPBC25H2.15
143
LLPS-Scp-0770
SPBC26H8.05c
O74789
SPBC26H8.05c
144
LLPS-Scp-0408
SPBC29A10.12
O94389
SPBC29A10.12
145
LLPS-Scp-1362
SPBC660.16
P78812
SPBC660.16
146
LLPS-Scp-1377
SPBPB21E7.04c
Q8NKC1
SPBPB21E7.04c
147
LLPS-Scp-0122
SPCC1020.02
O59757
spc7
148
LLPS-Scp-1173
SPCC1259.12c
O94712
SPCC1259.12c
149
LLPS-Scp-0426
SPBC1289.03c
P28748
spi1
150
LLPS-Scp-1500
SPAC31G5.09c
P27638
spk1
151
LLPS-Scp-1308
SPBC119.08
Q92398
spm1
152
LLPS-Scp-0079
SPAC4F10.11
O36023
spn1
153
LLPS-Scp-1658
SPAC27D7.13c
O42667
ssm4
154
LLPS-Scp-0684
SPAC664.11
P22774
ssp1
155
LLPS-Scp-0988
SPAC926.04c
P41887
swo1
156
LLPS-Scp-0629
SPCC23B6.03c
O74630
tel1
157
LLPS-Scp-1106
SPAC13C5.03
Q09684
tht1
158
LLPS-Scp-0823
SPBC17D11.05
O74760
tif32
159
LLPS-Scp-1341
SPBC691.02c
Q9C0W8
tip20
160
LLPS-Scp-0780
SPBC1A4.03c
P08096
top2
161
LLPS-Scp-0652
SPAP8A3.12c
Q9UT05
tpp2
162
LLPS-Scp-1584
SPAC630.13c
Q9UUG9
tsc2
163
LLPS-Scp-0221
SPBC32F12.04
P25295
tug1
164
LLPS-Scp-1480
SPCC1259.15c
O00103
ubc11
165
LLPS-Scp-0579
SPAC11G7.04
P0CH07
uep1
166
LLPS-Scp-0984
SPBC244.02c
O60188
utp6
167
LLPS-Scp-0553
SPAC9E9.14
O14296
vps24
168
LLPS-Scp-0846
SPBC409.07c
P33886
wis1
169
LLPS-Scp-0481
SPAC1805.17
P14068
xpo1
170
LLPS-Scp-1475
SPAC6B12.13
O14218
ypi1