• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
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  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Scp-1653
SPAC1805.16c

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Putative purine nucleoside phosphorylase
Gene Name: SPAC1805.16c
Ensembl Gene: SPAC1805.16c
Ensembl Protein: SPAC1805.16c.1
Organism: Schizosaccharomyces pombe
Taxa ID: 284812
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ FUNCTION

The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine and inosine (By similarity).

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblSPAC1805.16c.1SPAC1805.16c.1
UniProtQ9UTG1, PNPH_SCHPO
GeneBankCU329670CAB55857.1
RefSeqNM_001019356.2NP_593927.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MTATSFLHQA  KQQPHHTEPY  IKALEAREYI  IEQVPEELSK  PKVAIICGSG  LGTLASGLSA  60
61    PVYEVPYEDI  PHFHVSHVPG  HASKLYFAFL  GEKRVPTMIL  AGRYHSYEGY  PIEATTFPVR  120
121   LMKVMGVEVM  VVTNAAGGLN  QGFKVGDLMI  LKDHINFPGL  AGMNPLRGPN  AHEFGVRFPP  180
181   LSDAYDLELR  KLVYDAAKAH  KVSRTIHEGC  YAFVSGPCFE  TRAESRMLAL  MGADCVGMST  240
241   VPEVVVARHC  GIRVLAISLV  TNNVVVEESP  SAKDLVEVDS  NVMSKGAANH  LEVLEVGIAA  300
301   AADVRTMVET  IVNFI  315
Nucleotide CDS Sequence (FASTA)
1     ATGACTGCTA  CATCTTTTCT  TCACCAGGCA  AAACAGCAAC  CCCATCATAC  TGAACCTTAC  60
61    ATTAAAGCGC  TTGAGGCTCG  TGAATACATC  ATTGAACAAG  TCCCCGAAGA  GCTTTCCAAG  120
121   CCCAAAGTTG  CCATCATTTG  CGGTAGCGGT  TTGGGCACAT  TAGCCTCTGG  ATTGTCGGCT  180
181   CCAGTTTATG  AAGTTCCTTA  TGAAGATATT  CCTCACTTTC  ATGTTTCCCA  TGTTCCAGGT  240
241   CACGCATCCA  AATTGTACTT  TGCCTTTTTG  GGCGAGAAAC  GCGTTCCCAC  TATGATTTTG  300
301   GCTGGTCGTT  ACCACTCTTA  TGAGGGATAT  CCTATAGAAG  CTACCACGTT  TCCTGTTCGT  360
361   CTTATGAAAG  TCATGGGCGT  TGAAGTCATG  GTTGTTACCA  ACGCAGCTGG  CGGCTTGAAT  420
421   CAAGGTTTCA  AAGTTGGTGA  TTTGATGATT  CTTAAAGATC  ACATCAATTT  TCCTGGCCTC  480
481   GCGGGCATGA  ACCCTCTCAG  AGGCCCTAAT  GCACACGAAT  TTGGTGTACG  TTTCCCCCCA  540
541   TTATCGGATG  CTTATGATTT  AGAATTACGA  AAATTGGTTT  ACGATGCTGC  CAAGGCTCAC  600
601   AAGGTTAGCC  GTACAATTCA  CGAAGGTTGT  TATGCATTTG  TATCTGGTCC  GTGTTTTGAG  660
661   ACTCGCGCTG  AAAGTCGAAT  GCTTGCTCTT  ATGGGAGCTG  ATTGTGTCGG  CATGTCTACG  720
721   GTTCCCGAAG  TAGTCGTTGC  GCGTCATTGT  GGTATTCGTG  TTCTTGCCAT  TTCTTTGGTT  780
781   ACCAACAACG  TTGTTGTTGA  AGAGAGCCCC  TCTGCCAAAG  ACTTAGTGGA  GGTTGATTCG  840
841   AATGTCATGT  CTAAGGGTGC  TGCAAATCAC  TTGGAGGTTT  TGGAAGTTGG  TATCGCTGCC  900
901   GCGGCCGATG  TTCGTACCAT  GGTGGAGACG  ATTGTCAATT  TTATTTAA  948

▼ KEYWORD

ID
Family
Complete proteome
Cytoplasm
Glycosyltransferase
Nucleus
Reference proteome
Transferase

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Cellular Component
Cytosol
Cellular Component
Nucleus
Molecular Function
Purine-nucleoside phosphorylase activity
Biological Process
NAD biosynthesis via nicotinamide riboside salvage pathway
Biological Process
Purine nucleoside catabolic process

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Scc-1425Schizosaccharomyces cryophilus70.986e-159 454
LLPS-Scj-1288Schizosaccharomyces japonicus68.672e-147 424
LLPS-Tum-1203Tuber melanosporum55.033e-101 307
LLPS-Asc-0613Aspergillus clavatus54.774e-84 261
LLPS-Asf-0993Aspergillus flavus53.821e-93 288
LLPS-Yal-0523Yarrowia lipolytica53.334e-107 322
LLPS-Nef-0890Neosartorya fischeri53.252e-97 297
LLPS-Kop-0889Komagataella pastoris52.861e-90 279
LLPS-Ict-0043Ictidomys tridecemlineatus52.595e-39 141
LLPS-Lem-0092Leptosphaeria maculans52.441e-99 303
LLPS-Sac-1591Saccharomyces cerevisiae52.171e-84 265
LLPS-Asfu-1384Aspergillus fumigatus52.083e-97 297
LLPS-Phn-0818Phaeosphaeria nodorum51.972e-97 297
LLPS-Dos-1294Dothistroma septosporum51.483e-95 292
LLPS-Icp-3365Ictalurus punctatus51.453e-79 249
LLPS-Zyt-1534Zymoseptoria tritici51.36e-93 286
LLPS-Xet-3075Xenopus tropicalis51.281e-77 245
LLPS-Asg-0471Ashbya gossypii51.261e-78 249
LLPS-Pyt-0361Pyrenophora teres51.193e-90 279
LLPS-Pytr-0784Pyrenophora triticirepentis50.853e-89 276
LLPS-Asn-0958Aspergillus nidulans50.825e-94 288
LLPS-Ten-3266Tetraodon nigroviridis50.725e-79 249
LLPS-Abg-1982Absidia glauca50.52e-87 271
LLPS-Asm-2085Astyanax mexicanus50.362e-78 248
LLPS-Gaga-0736Gallus gallus50.22e-71 230
LLPS-Orl-0958Oryzias latipes50.06e-78 246
LLPS-Meg-3231Meleagris gallopavo50.04e-72 231
LLPS-Gaa-3691Gasterosteus aculeatus49.825e-78 246
LLPS-Dar-3227Danio rerio49.822e-75 239
LLPS-Ran-0829Rattus norvegicus49.641e-81 256
LLPS-Scm-1054Scophthalmus maximus49.645e-78 247
LLPS-Otg-2360Otolemur garnettii49.641e-80 253
LLPS-Mea-2874Mesocricetus auratus49.465e-83 259
LLPS-Mup-0635Mustela putorius furo49.454e-79 249
LLPS-Urm-3827Ursus maritimus49.457e-80 251
LLPS-Cap-0421Cavia porcellus49.442e-78 247
LLPS-Ere-0755Erinaceus europaeus49.281e-81 256
LLPS-Orc-1887Oryctolagus cuniculus49.274e-82 257
LLPS-Fia-0663Ficedula albicollis49.268e-77 243
LLPS-Fud-1037Fukomys damarensis48.911e-80 253
LLPS-Bot-3782Bos taurus48.911e-81 257
LLPS-Anc-0453Anolis carolinensis48.919e-78 246
LLPS-Orn-3078Oreochromis niloticus48.899e-74 236
LLPS-Mum-4563Mus musculus48.745e-81 254
LLPS-Loa-4577Loxodonta africana48.742e-82 258
LLPS-Aon-1909Aotus nancymaae48.727e-78 246
LLPS-Sus-0799Sus scrofa48.726e-80 252
LLPS-Aim-2918Ailuropoda melanoleuca48.726e-78 246
LLPS-Caj-1137Callithrix jacchus48.192e-78 247
LLPS-Maf-3862Macaca fascicularis48.183e-79 249
LLPS-Chs-2394Chlorocebus sabaeus48.183e-79 249
LLPS-Paa-0532Papio anubis48.185e-79 249
LLPS-Mal-2647Mandrillus leucophaeus48.183e-79 249
LLPS-Man-2394Macaca nemestrina48.183e-79 249
LLPS-Hos-0991Homo sapiens48.182e-78 248
LLPS-Rhb-4697Rhinopithecus bieti48.183e-79 250
LLPS-Mam-3565Macaca mulatta48.183e-79 249
LLPS-Poa-3319Pongo abelii48.182e-79 250
LLPS-Nol-1420Nomascus leucogenys48.182e-79 250
LLPS-Cas-0829Carlito syrichta48.184e-77 244
LLPS-Xim-2696Xiphophorus maculatus48.125e-78 246
LLPS-Scf-4159Scleropages formosus48.091e-70 227
LLPS-Sah-0422Sarcophilus harrisii48.064e-58 192
LLPS-Cea-0750Cercocebus atys48.013e-79 249
LLPS-Pap-1157Pan paniscus48.016e-79 249
LLPS-Pat-4374Pan troglodytes48.016e-79 249
LLPS-Fec-2827Felis catus47.992e-79 250
LLPS-Ora-1835Ornithorhynchus anatinus47.832e-44 155
LLPS-Dio-3480Dipodomys ordii47.831e-78 248
LLPS-Gog-0166Gorilla gorilla47.651e-78 248
LLPS-Myl-2417Myotis lucifugus47.656e-78 247
LLPS-Eqc-4407Equus caballus47.623e-77 246
LLPS-Caf-3142Canis familiaris47.463e-77 244
LLPS-Leo-3534Lepisosteus oculatus47.421e-78 248
LLPS-Spr-1246Sporisorium reilianum47.372e-81 256
LLPS-Ova-2884Ovis aries47.32e-1677.0
LLPS-Tag-2290Taeniopygia guttata47.271e-76 243
LLPS-Tar-2086Takifugu rubripes47.191e-72 233
LLPS-Ast-0453Aspergillus terreus47.122e-44 157
LLPS-Mod-2701Monodelphis domestica47.11e-74 238
LLPS-Pof-2930Poecilia formosa46.566e-78 246
LLPS-Lac-2044Latimeria chalumnae46.556e-74 236
LLPS-Cii-1149Ciona intestinalis46.474e-67 218
LLPS-Tut-2156Tursiops truncatus46.42e-76 243
LLPS-Anp-1451Anas platyrhynchos46.189e-73 233
LLPS-Blg-0528Blumeria graminis45.493e-72 234
LLPS-Usm-1050Ustilago maydis45.251e-73 236
LLPS-Miv-1012Microbotryum violaceum45.178e-77 245
LLPS-Cis-1668Ciona savignyi45.056e-70 226
LLPS-Pug-1224Puccinia graminis44.643e-62 207
LLPS-Mel-1518Melampsora laricipopulina43.633e-68 222
LLPS-Drm-0414Drosophila melanogaster42.352e-62 209
LLPS-Cae-1535Caenorhabditis elegans39.162e-56 192
LLPS-Pes-2626Pelodiscus sinensis30.835e-1268.2
LLPS-Cym-0604Cyanidioschyzon merolae26.534e-0651.6