• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Yal-1025
DBP6

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: ATP-dependent RNA helicase DBP6
Gene Name: DBP6, YALI0B22572g
Ensembl Gene: YALI0_B22572g
Ensembl Protein: CAG83480
Organism: Yarrowia lipolytica
Taxa ID: 284591
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblCAG83480CAG83480
UniProtQ6CDN5, DBP6_YARLI
GeneBankCR382128CAG83480.1
RefSeqXM_501227.1XP_501227.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MFTGVRRFDP  TQGGQASPVP  FKKVKHEEEE  SKPETNADEH  SEVEYEEESG  DDSMDEAEEA  60
61    KKPVEVKDEE  ESEDENLTAD  QKRKKKQEAA  NLAKRAEEKA  LERKRKREQH  MGEEDSDSED  120
121   DLAPIKISGN  NKIKLAKGTI  RAKGFEELPQ  TEIYEDKPDE  SATISRKTQL  QTQPILRNAT  180
181   YVEIDDVGSF  DEFDLSKNMM  KNLDTLGYTK  AFSVQKAVIP  WLLAQQKLLA  PDRKPDLLVS  240
241   ASTGSGKTAT  YGIPIIEKLR  DRIVPRIRAV  VVLPTKPLVM  QVRDVLENLS  KGSSLSVVAL  300
301   RNDRSTKRER  AVLETADIVV  AAPGRLVEQV  KENPELFSYI  EFLVVDEADR  LLGQDYYDWA  360
361   SVLQNNQQRA  QAGKTNLTEH  YVRNMQTLIF  SATLTANPEH  IASMDIHNPG  VFVIGSSDSY  420
421   SIPKSLTEIV  THVSAAEKPL  MLCELLVQRD  INRGVVFTKS  SETAARVARM  MEIMDADIFH  480
481   KDWKIAAVSA  ETSSVHRRRS  MKQFIDGKID  FLVCTDLVSR  GIDFVVDNVI  NYDIPSGKRE  540
541   YVHRVGRTAR  AGREGNAYTF  LTGSGEAKWF  REIGEFVGRT  QEVDATHINS  SHNDGYQEAL  600
601   AKLEEEV  607
Nucleotide CDS Sequence (FASTA)
1     ATGTTCACTG  GAGTTCGTCG  ATTTGACCCT  ACCCAGGGCG  GACAGGCGTC  GCCTGTACCA  60
61    TTCAAGAAGG  TCAAACACGA  GGAGGAGGAA  AGCAAGCCTG  AAACCAATGC  TGACGAGCAC  120
121   TCTGAGGTGG  AATATGAGGA  GGAGTCTGGG  GACGACTCCA  TGGATGAGGC  TGAGGAGGCC  180
181   AAGAAGCCCG  TGGAGGTCAA  GGACGAGGAG  GAGAGCGAAG  ATGAGAACCT  TACAGCCGAC  240
241   CAGAAGCGAA  AGAAGAAGCA  GGAAGCCGCC  AACCTGGCCA  AGCGAGCGGA  GGAAAAGGCT  300
301   CTAGAGCGAA  AGCGAAAGCG  AGAACAGCAT  ATGGGCGAGG  AGGACTCTGA  TAGTGAAGAT  360
361   GATCTGGCGC  CTATCAAGAT  TTCTGGCAAC  AACAAAATCA  AGCTTGCTAA  GGGAACCATT  420
421   CGAGCTAAGG  GCTTCGAGGA  GCTTCCCCAG  ACTGAAATCT  ATGAGGATAA  ACCCGATGAG  480
481   AGTGCAACCA  TCTCTCGAAA  GACCCAACTT  CAGACACAGC  CCATTTTGCG  AAATGCTACT  540
541   TATGTGGAAA  TTGACGATGT  TGGATCATTT  GATGAGTTTG  ATCTGAGCAA  AAATATGATG  600
601   AAGAACCTGG  ACACTTTAGG  ATACACAAAG  GCATTTTCTG  TGCAGAAGGC  AGTCATTCCT  660
661   TGGCTTCTGG  CCCAGCAAAA  GCTCCTTGCC  CCCGATCGAA  AGCCCGATCT  TCTTGTTTCT  720
721   GCATCCACCG  GTTCCGGTAA  GACCGCCACT  TACGGAATCC  CCATTATCGA  GAAGCTCCGA  780
781   GACCGTATTG  TTCCTCGAAT  CAGAGCTGTG  GTTGTACTCC  CTACAAAGCC  CCTGGTCATG  840
841   CAAGTCCGAG  ACGTGCTTGA  AAACCTATCC  AAGGGATCTT  CTTTGTCTGT  TGTGGCTCTT  900
901   CGAAACGACC  GAAGCACCAA  ACGTGAACGG  GCTGTTCTGG  AGACTGCCGA  TATCGTTGTG  960
961   GCAGCCCCTG  GTCGACTTGT  GGAGCAAGTG  AAGGAGAACC  CCGAGCTCTT  CTCTTACATC  1020
1021  GAATTTCTGG  TGGTTGACGA  GGCCGATCGT  CTGCTTGGCC  AGGACTACTA  CGACTGGGCC  1080
1081  TCTGTGTTGC  AGAACAACCA  GCAGCGGGCC  CAGGCTGGTA  AGACCAACCT  CACTGAGCAC  1140
1141  TACGTTCGAA  ACATGCAAAC  ACTTATTTTC  TCAGCCACCC  TCACAGCCAA  CCCCGAACAC  1200
1201  ATTGCATCCA  TGGACATCCA  CAATCCTGGC  GTTTTTGTCA  TTGGTAGTTC  TGACAGCTAC  1260
1261  TCTATTCCCA  AGAGTCTTAC  AGAGATTGTC  ACCCACGTGT  CTGCTGCCGA  GAAGCCTCTT  1320
1321  ATGCTGTGCG  AGCTGCTAGT  GCAGAGAGAT  ATCAACAGAG  GCGTGGTGTT  CACTAAGAGT  1380
1381  TCCGAAACTG  CTGCTCGTGT  GGCTCGCATG  ATGGAGATTA  TGGACGCGGA  CATTTTCCAC  1440
1441  AAGGATTGGA  AGATAGCGGC  TGTTTCTGCC  GAGACTTCTT  CTGTGCACCG  ACGACGGTCC  1500
1501  ATGAAGCAGT  TTATTGATGG  CAAGATCGAC  TTTCTGGTCT  GTACCGATTT  GGTTTCTCGA  1560
1561  GGTATCGATT  TCGTGGTGGA  TAATGTGATC  AACTACGATA  TCCCTAGTGG  AAAGCGAGAG  1620
1621  TATGTGCATC  GAGTGGGTCG  AACTGCCCGA  GCAGGCAGAG  AAGGTAACGC  ATACACCTTC  1680
1681  CTCACTGGCT  CTGGAGAAGC  CAAGTGGTTC  CGGGAGATTG  GCGAGTTTGT  GGGTCGAACC  1740
1741  CAGGAGGTGG  ATGCCACTCA  TATCAACAGT  TCCCATAACG  ACGGATACCA  GGAGGCTCTT  1800
1801  GCCAAGCTGG  AGGAGGAGGT  TTAG  1824

▼ KEYWORD

ID
Family
ATP-binding
Complete proteome
Helicase
Hydrolase
Nucleotide-binding
Nucleus
Reference proteome
Ribosome biogenesis
RNA-binding
rRNA processing

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Nucleolus
Molecular Function
ATP binding
Molecular Function
Helicase activity
Molecular Function
RNA binding
Biological Process
RRNA processing

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Asm-0839Astyanax mexicanus36.483e-57 210
LLPS-Scf-1350Scleropages formosus36.34e-59 215
LLPS-Orn-2753Oreochromis niloticus36.244e-70 245
LLPS-Ora-0720Ornithorhynchus anatinus36.194e-60 217
LLPS-Asg-0431Ashbya gossypii35.848e-57 207
LLPS-Xim-0927Xiphophorus maculatus35.836e-66 234
LLPS-Kop-0112Komagataella pastoris35.771e-74 258
LLPS-Scj-0228Schizosaccharomyces japonicus35.766e-79 268
LLPS-Crn-0212Cryptococcus neoformans35.311e-74 259
LLPS-Spr-0387Sporisorium reilianum35.291e-70 250
LLPS-Gaa-0248Gasterosteus aculeatus34.982e-66 235
LLPS-Icp-1542Ictalurus punctatus34.847e-56 206
LLPS-Pap-2647Pan paniscus34.814e-62 223
LLPS-Pat-3862Pan troglodytes34.814e-64 228
LLPS-Poa-1379Pongo abelii34.62e-63 227
LLPS-Ten-0704Tetraodon nigroviridis34.521e-63 227
LLPS-Orl-2457Oryzias latipes34.437e-63 224
LLPS-Pof-2658Poecilia formosa34.369e-60 216
LLPS-Mea-0375Mesocricetus auratus34.351e-58 213
LLPS-Scc-0551Schizosaccharomyces cryophilus34.294e-71 246
LLPS-Tar-0396Takifugu rubripes34.282e-62 223
LLPS-Scp-0675Schizosaccharomyces pombe34.261e-73 253
LLPS-Cea-0795Cercocebus atys34.241e-63 227
LLPS-Man-0943Macaca nemestrina34.176e-63 226
LLPS-Nol-1504Nomascus leucogenys34.063e-58 211
LLPS-Chs-0203Chlorocebus sabaeus34.032e-65 232
LLPS-Fud-0052Fukomys damarensis34.028e-61 216
LLPS-Ict-2042Ictidomys tridecemlineatus33.831e-63 226
LLPS-Cis-0164Ciona savignyi33.837e-60 216
LLPS-Hos-0258Homo sapiens33.812e-64 230
LLPS-Cap-0587Cavia porcellus33.669e-59 213
LLPS-Mod-2203Monodelphis domestica33.651e-57 210
LLPS-Paa-0741Papio anubis33.619e-64 228
LLPS-Mum-1749Mus musculus33.571e-59 216
LLPS-Mup-0450Mustela putorius furo33.552e-62 220
LLPS-Urm-2537Ursus maritimus33.475e-60 217
LLPS-Aon-2509Aotus nancymaae33.415e-61 219
LLPS-Maf-3101Macaca fascicularis33.48e-63 225
LLPS-Aim-0094Ailuropoda melanoleuca33.44e-62 221
LLPS-Ran-1029Rattus norvegicus33.332e-58 212
LLPS-Loa-0010Loxodonta africana33.265e-60 216
LLPS-Orc-1306Oryctolagus cuniculus33.262e-59 213
LLPS-Caf-1123Canis familiaris33.263e-61 220
LLPS-Gog-1297Gorilla gorilla33.213e-64 228
LLPS-Fec-2738Felis catus33.27e-64 228
LLPS-Chc-0657Chondrus crispus33.111e-52 195
LLPS-Scm-0962Scophthalmus maximus33.052e-63 227
LLPS-Dar-2106Danio rerio33.043e-65 232
LLPS-Ova-1411Ovis aries32.912e-60 218
LLPS-Lep-0829Leersia perrieri32.93e-48 184
LLPS-Sah-0752Sarcophilus harrisii32.83e-60 218
LLPS-Otg-2111Otolemur garnettii32.774e-60 218
LLPS-Xet-1845Xenopus tropicalis32.762e-54 202
LLPS-Gaga-1265Gallus gallus32.689e-60 216
LLPS-Tag-2566Taeniopygia guttata32.682e-60 214
LLPS-Bot-0032Bos taurus32.492e-60 218
LLPS-Anp-2752Anas platyrhynchos32.19e-59 212
LLPS-Meg-0596Meleagris gallopavo31.881e-59 214
LLPS-Fia-3039Ficedula albicollis31.884e-57 209
LLPS-Pes-0396Pelodiscus sinensis31.743e-59 212
LLPS-Ors-0210Oryza sativa31.686e-48 183
LLPS-Orbr-0927Oryza brachyantha31.685e-48 184
LLPS-Orr-0043Oryza rufipogon31.687e-48 183
LLPS-Orb-0251Oryza barthii31.687e-48 183
LLPS-Orni-1510Oryza nivara31.681e-47 183
LLPS-Orgl-0240Oryza glumaepatula31.681e-47 182
LLPS-Brn-0764Brassica napus31.656e-42 162
LLPS-Caj-1873Callithrix jacchus31.653e-63 226
LLPS-Asni-0100Aspergillus niger31.573e-54 200
LLPS-Sei-1129Setaria italica31.472e-44 170
LLPS-Bro-1105Brassica oleracea31.427e-42 162
LLPS-Amt-0857Amborella trichopoda31.419e-47 179
LLPS-Ori-0555Oryza indica31.416e-47 180
LLPS-Hov-0912Hordeum vulgare31.412e-45 176
LLPS-Brd-0328Brachypodium distachyon31.418e-46 177
LLPS-Tra-0739Triticum aestivum31.412e-45 176
LLPS-Leo-0657Lepisosteus oculatus31.44e-52 195
LLPS-Hea-0016Helianthus annuus31.274e-49 182
LLPS-Cii-0134Ciona intestinalis31.242e-60 218
LLPS-Cae-0387Caenorhabditis elegans31.222e-47 181
LLPS-Viv-0890Vitis vinifera31.27e-44 169
LLPS-Sob-1735Sorghum bicolor31.173e-46 178
LLPS-Zem-0539Zea mays31.171e-46 179
LLPS-Mae-0035Manihot esculenta31.153e-46 178
LLPS-Glm-0116Glycine max31.143e-48 183
LLPS-Gor-0880Gossypium raimondii31.096e-46 177
LLPS-Prp-0029Prunus persica30.988e-51 188
LLPS-Sac-0257Saccharomyces cerevisiae30.926e-44 171
LLPS-Php-0560Physcomitrella patens30.917e-44 172
LLPS-Sem-0432Selaginella moellendorffii30.843e-50 187
LLPS-Drm-0644Drosophila melanogaster30.774e-58 212
LLPS-Abg-0372Absidia glauca30.779e-42 165
LLPS-Art-0459Arabidopsis thaliana30.732e-45 176
LLPS-Arl-0067Arabidopsis lyrata30.737e-45 174
LLPS-Orp-0652Oryza punctata30.714e-46 178
LLPS-Osl-0116Ostreococcus lucimarinus30.696e-45 174
LLPS-Nec-0166Neurospora crassa30.653e-41 164
LLPS-Via-0901Vigna angularis30.636e-44 171
LLPS-Nia-0790Nicotiana attenuata30.56e-45 170
LLPS-Ast-0542Aspergillus terreus30.342e-42 167
LLPS-Sol-0216Solanum lycopersicum30.256e-44 167
LLPS-Thc-0354Theobroma cacao30.253e-45 175
LLPS-Phv-1167Phaseolus vulgaris30.182e-45 172
LLPS-Lac-0035Latimeria chalumnae30.151e-46 179
LLPS-Coc-0039Corchorus capsularis30.154e-47 181
LLPS-Tut-0005Tursiops truncatus30.156e-48 183
LLPS-Cus-1536Cucumis sativus30.131e-43 170
LLPS-Mua-1648Musa acuminata30.12e-44 172
LLPS-Aso-0460Aspergillus oryzae30.088e-42 166
LLPS-Asf-0531Aspergillus flavus30.086e-42 166
LLPS-Dac-0699Daucus carota30.052e-43 166
LLPS-Sot-0691Solanum tuberosum30.031e-41 164
LLPS-Nef-0007Neosartorya fischeri30.01e-42 168
LLPS-Orm-0996Oryza meridionalis30.01e-44 171
LLPS-Pot-0241Populus trichocarpa29.951e-44 173
LLPS-Eqc-0806Equus caballus29.94e-48 184
LLPS-Cas-1894Carlito syrichta29.92e-46 179
LLPS-Sus-0073Sus scrofa29.94e-48 184
LLPS-Asn-0469Aspergillus nidulans29.894e-42 166
LLPS-Brr-0338Brassica rapa29.854e-45 176
LLPS-Asfu-1172Aspergillus fumigatus29.771e-42 168
LLPS-Asc-0287Aspergillus clavatus29.777e-43 169
LLPS-Mam-2084Macaca mulatta29.652e-47 181
LLPS-Dio-1076Dipodomys ordii29.653e-46 178
LLPS-Met-1058Medicago truncatula29.581e-42 167
LLPS-Rhb-0320Rhinopithecus bieti29.471e-46 179
LLPS-Myl-2693Myotis lucifugus29.41e-46 179
LLPS-Map-0031Magnaporthe poae29.233e-41 164
LLPS-Fus-1155Fusarium solani29.094e-41 163
LLPS-Vir-0250Vigna radiata29.022e-43 168
LLPS-Cym-0355Cyanidioschyzon merolae29.07e-44 169
LLPS-Pytr-0017Pyrenophora triticirepentis28.851e-45 175
LLPS-Gas-0135Galdieria sulphuraria28.641e-41 163
LLPS-Mal-1433Mandrillus leucophaeus28.215e-42 166