LLPS-Mum-1749
Ddx51

▼ OVERVIEW

Status: Reviewed
Protein Name: ATP-dependent RNA helicase DDX51; DEAD box protein 51
Gene Name: Ddx51
Ensembl Gene: ENSMUSG00000029504.5
Ensembl Protein: ENSMUSP00000121481.1
Organism: Mus musculus
Taxa ID: 10090
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateDescriptionTissue/CellPMIDs

▼ FUNCTION

ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MALFHIARYA  GPEAAGQGDT  DAEAGSRARV  LLERLQNRAR  ERQQREPELE  TTGTAGEGEA  60
61    AAAGKRRRRP  RRRRRVSGSA  TPNSEAPRAK  RRKADKDVDA  GRGEEAPEEL  SAGAEDPGAN  120
121   PQEDVQRPPA  PGRVLGDFAR  RKTPKVQPFL  PAWLAKPSCV  KKSVTEDLTP  IEDIPEVHPD  180
181   LQKQLRANGI  TSYFPVQAAV  IPALLESADH  GFLIGRGGYQ  PSDLCVSAPT  GSGKTLAFVI  240
241   PVVQALLHRV  VCHIRALVVL  PTKELAQQVS  KVFNIYTDTT  PLRVALVTGQ  KSLAKEQESL  300
301   VQKTADGFRC  LADIVVATPG  RLVDHIDQTP  GFSLQQLRFL  IIDEADRMID  SMHQSWLPRV  360
361   VAAAFYSEGP  TGSCALLQRT  QPQALTAAST  CVPQMPLQKL  LFSATLTQDP  EKLQRLGLYQ  420
421   PRLFSTRLGQ  QSPKDTAEVD  ENSGKYTFPV  GLTHHYVPCR  LSSKPLIVLH  LVLRMSCSRA  480
481   LCFTNSRENS  HRLYLLAQAF  GGVSVAEFSS  RYGPGQRKKI  LKQFEQGKIQ  LLISTDATAR  540
541   GIDVQGVELV  INYDAPQYLR  TYVHRVGRTA  RAGKTGQAFT  LLLKVQERKF  LQMVSEAGVP  600
601   ELTHHEIPRK  LLQPLVARYE  TALSQLEKTV  KEEQKLKAA  639
Nucleotide CDS Sequence (FASTA)
1     ATGGCGCTGT  TCCACATAGC  GCGGTACGCG  GGCCCAGAGG  CCGCGGGGCA  GGGGGATACG  60
61    GACGCAGAGG  CGGGCAGCCG  GGCTCGAGTG  CTGCTCGAGC  GGCTGCAGAA  CAGAGCCCGT  120
121   GAGCGACAGC  AGCGGGAGCC  GGAGCTCGAG  ACCACAGGAA  CGGCCGGGGA  AGGGGAAGCG  180
181   GCAGCAGCAG  GCAAGCGGCG  ACGGCGGCCC  CGACGGCGGC  GTCGGGTGAG  CGGCTCGGCG  240
241   ACTCCGAACT  CGGAGGCTCC  TAGGGCGAAG  CGGCGGAAAG  CGGACAAGGA  CGTGGACGCA  300
301   GGGAGAGGTG  AGGAGGCTCC  GGAGGAGCTC  AGTGCCGGCG  CAGAGGACCC  GGGTGCGAAC  360
361   CCTCAGGAGG  ATGTCCAGAG  ACCCCCGGCT  CCAGGCCGGG  TGCTGGGGGA  CTTTGCAAGA  420
421   AGAAAGACGC  CGAAGGTTCA  GCCTTTCCTG  CCAGCATGGT  TGGCTAAGCC  AAGCTGTGTC  480
481   AAAAAGAGTG  TCACCGAAGA  TCTCACTCCC  ATTGAGGACA  TCCCTGAGGT  TCACCCTGAC  540
541   CTGCAGAAGC  AGTTGAGAGC  TAATGGCATC  ACTTCCTACT  TTCCAGTCCA  GGCAGCTGTG  600
601   ATTCCCGCCC  TCCTCGAAAG  TGCTGACCAT  GGGTTTCTCA  TAGGCAGAGG  TGGCTACCAA  660
661   CCTAGTGACC  TCTGCGTCTC  TGCCCCAACG  GGCAGTGGGA  AAACACTGGC  CTTTGTCATC  720
721   CCCGTGGTAC  AGGCCCTGTT  GCATCGAGTG  GTCTGCCACA  TCCGTGCACT  GGTTGTACTT  780
781   CCCACTAAGG  AGCTGGCCCA  ACAGGTGAGC  AAAGTATTCA  ACATCTACAC  AGACACCACG  840
841   CCTCTGAGGG  TTGCCTTGGT  GACTGGACAG  AAGTCGCTGG  CTAAGGAGCA  GGAGAGTCTT  900
901   GTCCAGAAGA  CAGCAGATGG  TTTCCGTTGC  CTGGCCGACA  TTGTGGTGGC  CACACCTGGC  960
961   CGCTTGGTGG  ACCACATTGA  CCAGACTCCA  GGATTCAGCC  TCCAGCAGCT  CCGCTTCCTG  1020
1021  ATCATTGATG  AGGCTGACCG  GATGATAGAC  AGCATGCACC  AGTCCTGGCT  GCCACGAGTG  1080
1081  GTGGCGGCAG  CCTTCTACAG  TGAGGGCCCC  ACGGGTTCCT  GTGCCCTGCT  CCAGAGGACA  1140
1141  CAGCCCCAGG  CTCTGACTGC  TGCCAGCACC  TGTGTCCCCC  AGATGCCTCT  GCAGAAGCTA  1200
1201  CTGTTCTCAG  CCACACTGAC  CCAGGACCCC  GAGAAGCTGC  AGCGCCTTGG  CCTCTACCAG  1260
1261  CCACGGCTTT  TCTCCACAAG  GCTGGGACAA  CAAAGTCCTA  AAGACACAGC  TGAGGTGGAT  1320
1321  GAAAACTCGG  GGAAGTACAC  CTTCCCCGTG  GGGCTCACGC  ATCACTATGT  GCCGTGTAGA  1380
1381  CTCAGCTCGA  AGCCACTCAT  TGTCTTACAC  CTGGTCCTCA  GGATGAGCTG  CTCAAGGGCT  1440
1441  CTTTGCTTCA  CCAACTCCCG  AGAAAACTCC  CACAGGCTGT  ACCTATTAGC  ACAAGCTTTT  1500
1501  GGGGGTGTGA  GTGTGGCTGA  ATTCTCCTCC  CGCTATGGGC  CTGGCCAAAG  GAAGAAAATC  1560
1561  TTGAAGCAGT  TTGAACAAGG  AAAGATCCAG  CTCCTTATCA  GCACAGATGC  TACTGCTCGA  1620
1621  GGCATTGATG  TGCAGGGTGT  GGAGCTGGTG  ATCAACTACG  ATGCCCCACA  ATATCTGAGG  1680
1681  ACCTATGTGC  ACAGGGTCGG  GAGAACAGCT  CGAGCCGGGA  AAACTGGACA  GGCATTCACA  1740
1741  CTTCTCTTGA  AAGTGCAGGA  AAGGAAGTTC  CTTCAGATGG  TGTCAGAAGC  TGGGGTGCCT  1800
1801  GAGCTGACAC  ACCATGAGAT  CCCCAGGAAG  CTCCTGCAGC  CGCTGGTTGC  TCGTTATGAG  1860
1861  ACAGCCTTGT  CTCAGTTGGA  GAAAACTGTC  AAGGAGGAGC  AGAAACTGAA  GGCAGCCTAG  1920

▼ KEYWORD

ID
Family
Acetylation
ATP-binding
Complete proteome
Helicase
Hydrolase
Nucleotide-binding
Nucleus
Phosphoprotein
Reference proteome
Ribosome biogenesis
RNA-binding
rRNA processing

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Nucleolus
Molecular Function
ATP binding
Molecular Function
Helicase activity
Molecular Function
RNA binding
Biological Process
RRNA processing

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ran-1029Rattus norvegicus90.770.01154
LLPS-Fud-0052Fukomys damarensis84.770.0 790
LLPS-Mea-0375Mesocricetus auratus84.560.01078
LLPS-Dio-0846Dipodomys ordii83.543e-90 284
LLPS-Ict-2042Ictidomys tridecemlineatus83.390.0 909
LLPS-Mal-0348Mandrillus leucophaeus83.032e-91 286
LLPS-Pap-2647Pan paniscus82.030.0 865
LLPS-Orc-1306Oryctolagus cuniculus81.010.0 832
LLPS-Mup-0450Mustela putorius furo78.70.0 798
LLPS-Nol-1504Nomascus leucogenys78.240.0 843
LLPS-Aim-0094Ailuropoda melanoleuca77.180.0 847
LLPS-Urm-2537Ursus maritimus75.890.0 810
LLPS-Pat-3862Pan troglodytes75.680.0 927
LLPS-Poa-1379Pongo abelii75.650.0 917
LLPS-Loa-0010Loxodonta africana75.440.0 852
LLPS-Gog-1297Gorilla gorilla74.880.0 899
LLPS-Hos-0258Homo sapiens74.660.0 925
LLPS-Chs-0203Chlorocebus sabaeus74.550.0 922
LLPS-Aon-2509Aotus nancymaae74.410.0 917
LLPS-Caj-1873Callithrix jacchus74.40.0 937
LLPS-Cea-0795Cercocebus atys74.360.0 920
LLPS-Cap-0587Cavia porcellus74.340.0 924
LLPS-Paa-0741Papio anubis74.060.0 917
LLPS-Eqc-2780Equus caballus73.920.0 805
LLPS-Maf-3101Macaca fascicularis73.840.0 925
LLPS-Man-0943Macaca nemestrina73.690.0 918
LLPS-Ova-1411Ovis aries73.430.0 895
LLPS-Fec-2738Felis catus73.260.0 900
LLPS-Myl-1490Myotis lucifugus72.780.0 684
LLPS-Bot-0032Bos taurus72.230.0 888
LLPS-Otg-2111Otolemur garnettii70.940.0 895
LLPS-Caf-1123Canis familiaris70.110.0 829
LLPS-Sah-0752Sarcophilus harrisii69.780.0 765
LLPS-Pes-0396Pelodiscus sinensis66.460.0 659
LLPS-Tag-2566Taeniopygia guttata65.440.0 677
LLPS-Fia-3039Ficedula albicollis64.060.0 695
LLPS-Mod-2203Monodelphis domestica63.810.0 759
LLPS-Sus-0534Sus scrofa63.10.0 652
LLPS-Meg-0596Meleagris gallopavo62.980.0 712
LLPS-Anp-2752Anas platyrhynchos62.480.0 709
LLPS-Ora-0720Ornithorhynchus anatinus62.010.0 745
LLPS-Gaga-1265Gallus gallus61.40.0 704
LLPS-Dar-2106Danio rerio59.60.0 604
LLPS-Tar-0396Takifugu rubripes59.280.0 599
LLPS-Orn-2753Oreochromis niloticus58.570.0 598
LLPS-Xim-0927Xiphophorus maculatus57.850.0 588
LLPS-Pof-2658Poecilia formosa57.060.0 566
LLPS-Icp-1542Ictalurus punctatus56.510.0 581
LLPS-Scm-0962Scophthalmus maximus55.520.0 600
LLPS-Scf-1350Scleropages formosus55.440.0 587
LLPS-Asm-0839Astyanax mexicanus55.350.0 575
LLPS-Leo-0657Lepisosteus oculatus52.90.0 559
LLPS-Orl-2457Oryzias latipes52.130.0 611
LLPS-Xet-1845Xenopus tropicalis51.870.0 637
LLPS-Gaa-0248Gasterosteus aculeatus49.850.0 610
LLPS-Lac-0355Latimeria chalumnae49.640.0 598
LLPS-Ten-0704Tetraodon nigroviridis48.830.0 567
LLPS-Cis-0164Ciona savignyi43.223e-116 368
LLPS-Drm-0644Drosophila melanogaster40.843e-103 335
LLPS-Spr-0387Sporisorium reilianum39.575e-85 290
LLPS-Usm-0369Ustilago maydis39.366e-85 290
LLPS-Miv-0197Microbotryum violaceum39.322e-80 280
LLPS-Zem-0272Zea mays39.32e-97 315
LLPS-Cii-0134Ciona intestinalis39.062e-108 348
LLPS-Orp-0571Oryza punctata38.561e-93 306
LLPS-Sob-0692Sorghum bicolor38.342e-95 310
LLPS-Scj-0228Schizosaccharomyces japonicus38.287e-93 305
LLPS-Scp-0675Schizosaccharomyces pombe37.921e-99 323
LLPS-Thc-2034Theobroma cacao37.916e-97 313
LLPS-Orm-0996Oryza meridionalis37.848e-96 311
LLPS-Php-1726Physcomitrella patens37.481e-87 290
LLPS-Arl-1093Arabidopsis lyrata37.434e-90 296
LLPS-Dac-0283Daucus carota37.438e-94 306
LLPS-Sei-1129Setaria italica37.44e-90 296
LLPS-Tra-0793Triticum aestivum37.382e-93 305
LLPS-Ori-0852Oryza indica37.353e-94 306
LLPS-Orr-0353Oryza rufipogon37.352e-94 306
LLPS-Gor-0101Gossypium raimondii37.351e-97 315
LLPS-Brd-0009Brachypodium distachyon37.31e-89 295
LLPS-Brn-0050Brassica napus37.38e-91 298
LLPS-Orni-0179Oryza nivara37.262e-94 307
LLPS-Ors-0227Oryza sativa37.262e-94 307
LLPS-Orbr-0412Oryza brachyantha37.261e-95 310
LLPS-Hov-0407Hordeum vulgare37.141e-91 301
LLPS-Brr-0995Brassica rapa37.13e-90 296
LLPS-Mae-0775Manihot esculenta37.095e-92 301
LLPS-Abg-0003Absidia glauca37.082e-95 313
LLPS-Bro-1370Brassica oleracea37.083e-90 296
LLPS-Org-1226Oryza glaberrima37.071e-93 305
LLPS-Art-2045Arabidopsis thaliana37.033e-88 291
LLPS-Prp-0029Prunus persica37.023e-93 304
LLPS-Scc-0551Schizosaccharomyces cryophilus36.886e-88 292
LLPS-Met-1089Medicago truncatula36.755e-94 305
LLPS-Sem-0432Selaginella moellendorffii36.656e-87 287
LLPS-Hea-0840Helianthus annuus36.631e-92 302
LLPS-Cus-0210Cucumis sativus36.572e-91 299
LLPS-Viv-0890Vitis vinifera36.497e-88 290
LLPS-Pot-1481Populus trichocarpa36.458e-89 292
LLPS-Mua-0632Musa acuminata36.319e-96 310
LLPS-Tru-0485Triticum urartu36.038e-74 250
LLPS-Crn-0212Cryptococcus neoformans36.021e-77 268
LLPS-Put-0914Puccinia triticina35.869e-81 280
LLPS-Sol-0937Solanum lycopersicum35.86e-89 292
LLPS-Pug-0224Puccinia graminis35.81e-75 265
LLPS-Nia-0581Nicotiana attenuata35.88e-88 290
LLPS-Coc-0050Corchorus capsularis35.793e-89 293
LLPS-Glm-0116Glycine max35.765e-82 277
LLPS-Phv-1167Phaseolus vulgaris35.735e-87 287
LLPS-Sot-1421Solanum tuberosum35.437e-89 292
LLPS-Mel-0401Melampsora laricipopulina35.377e-79 274
LLPS-Lep-0930Leersia perrieri35.228e-80 269
LLPS-Kop-0112Komagataella pastoris34.737e-57 210
LLPS-Chc-0657Chondrus crispus34.562e-65 232
LLPS-Amt-0857Amborella trichopoda34.431e-49 188
LLPS-Tum-0350Tuber melanosporum33.955e-63 226
LLPS-Yal-1025Yarrowia lipolytica33.573e-60 218
LLPS-Asni-0100Aspergillus niger32.951e-61 221
LLPS-Orgl-0240Oryza glumaepatula32.753e-49 187
LLPS-Orb-0251Oryza barthii32.753e-49 188
LLPS-Coo-1109Colletotrichum orbiculare32.432e-49 185
LLPS-Ast-0542Aspergillus terreus32.431e-49 189
LLPS-Cog-1182Colletotrichum gloeosporioides32.281e-50 188
LLPS-Scs-0568Sclerotinia sclerotiorum32.259e-49 186
LLPS-Cogr-0131Colletotrichum graminicola32.241e-50 192
LLPS-Ved-0926Verticillium dahliae32.183e-48 181
LLPS-Mao-0449Magnaporthe oryzae32.075e-48 184
LLPS-Nef-0007Neosartorya fischeri32.032e-53 201
LLPS-Asc-0287Aspergillus clavatus31.955e-52 196
LLPS-Trr-0013Trichoderma reesei31.892e-49 188
LLPS-Asfu-1172Aspergillus fumigatus31.818e-53 199
LLPS-Nec-0166Neurospora crassa31.743e-50 191
LLPS-Asn-0469Aspergillus nidulans31.478e-52 196
LLPS-Phn-0205Phaeosphaeria nodorum31.283e-50 191
LLPS-Aso-0460Aspergillus oryzae31.256e-52 196
LLPS-Asf-0531Aspergillus flavus31.254e-52 196
LLPS-Via-0901Vigna angularis31.243e-48 184
LLPS-Zyt-0056Zymoseptoria tritici31.121e-49 189
LLPS-Vir-0250Vigna radiata31.067e-48 182
LLPS-Cae-0460Caenorhabditis elegans31.032e-55 204
LLPS-Gas-0135Galdieria sulphuraria30.731e-49 187
LLPS-Sac-0173Saccharomyces cerevisiae30.136e-54 200
LLPS-Pytr-0017Pyrenophora triticirepentis30.07e-56 206
LLPS-Tut-0005Tursiops truncatus29.175e-52 196
LLPS-Mam-2084Macaca mulatta28.954e-51 193
LLPS-Cas-1894Carlito syrichta28.956e-49 187
LLPS-Rhb-0320Rhinopithecus bieti28.953e-50 191
LLPS-Lem-0216Leptosphaeria maculans28.912e-57 211
LLPS-Asg-0431Ashbya gossypii28.578e-48 182