• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Xim-3263

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Calcium-transporting ATPase
Ensembl Gene: ENSXMAG00000000856.2
Ensembl Protein: ENSXMAP00000000896.2
Organism: Xiphophorus maculatus
Taxa ID: 8083
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
P-body, Stress granulePredicted from orthologs(View)

▼ FUNCTION

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MLKKRELLLS  QNQPCGEDET  MVPVLTSRKA  SELPVNEVAC  VLQADLQAGL  TQEEVTRRRV  60
61    YHGWNEFDIS  EDEPLWRKYI  SQFKDPLILL  LLASAVISVV  MHQLDDAISI  TVAIIIVVTV  120
121   AFVQEYRSEK  SLEELGKLVP  PECHCIRDGQ  LEHLLARDLV  PGDTVCLSVG  ERVPADLRLY  180
181   EASDLSIDES  SLTGETHPSS  KSTTPQPPAS  NGNIASRSNI  AFMGTLVRCG  KAKGIVIGTG  240
241   ENSEFGEVFK  MMQAEEAPKT  PLQKSMDLLG  KQLSLYSFGI  IGVIMLVGWL  QGKRILDMFT  300
301   IGVSLAVAAI  PEGLPIVVTV  TLALGVMRMV  KKRAIVKKLP  IVETLSCCNV  ICSDKTGTLT  360
361   KNEMTVTQVF  TSDGLHAEVT  GVGYNGTGEV  LLDGEVVHGL  ACPSISKVVE  VGCVCNDSII  420
421   RNQNLLGRPT  EGALIALAMK  MGLESVQQEF  IRLEEHPFTS  EQKWMAVRCV  HRTQQDKSGV  480
481   YFMKGAYEQV  IRFCSSYNSR  GSNLPLTHQQ  RELYQQQISY  MGTSGLRVLA  FASGSQMGSL  540
541   TFLGLVGIID  PPREGVKEAV  ATLLNSGVAI  KMITGDSQET  AVSIANRLGL  YSKGCHCLSG  600
601   EEVDHLDLQE  LSNIVPRVGV  FYRASPRHKL  KIVKSLQNLG  AVVAMTGDGV  NDAVALKAAD  660
661   IGVAMGKTGT  DVCKEAADMI  LVDDDFQTIM  SAIEEGKGIY  NNIKNFVRFQ  LSTSIAALTL  720
721   ISLATLMNFP  NPLNAMQILW  INIIMDGPPA  QSLGVEPVDR  DVISKPPRNV  KDTILTRSLL  780
781   VKVLVSAFII  VCGTLFVFWR  ELQDNMITPR  DTTMTFTCFV  FFDMFNALSS  RSQTRMVHEM  840
841   GLCSNRTFCY  AVLASIMGQL  LVIYFPPLQS  IFQTESLSIL  DLLFLLSLTS  SVCVVSEVIK  900
901   KVERCRGAER  RPPSDCSLEV  920
Nucleotide CDS Sequence (FASTA)
1     ATGCTGAAGA  AACGGGAGCT  GTTGCTTTCC  CAGAACCAGC  CCTGTGGTGA  AGATGAGACC  60
61    ATGGTCCCGG  TACTGACGTC  CAGAAAAGCC  TCAGAACTCC  CGGTTAATGA  AGTAGCGTGC  120
121   GTCCTGCAGG  CGGACTTGCA  GGCTGGTCTG  ACCCAGGAGG  AAGTGACCCG  GCGGAGGGTC  180
181   TACCACGGCT  GGAACGAGTT  CGACATCAGT  GAAGACGAGC  CGCTATGGAG  GAAGTACATC  240
241   TCCCAGTTCA  AAGATCCTCT  CATCCTGCTG  CTGCTCGCCT  CGGCCGTCAT  CAGTGTTGTC  300
301   ATGCACCAGT  TAGATGACGC  CATCAGCATC  ACCGTGGCCA  TCATCATCGT  GGTGACGGTC  360
361   GCCTTCGTGC  AGGAATACCG  CTCAGAGAAA  TCGTTGGAGG  AGCTGGGGAA  GCTGGTGCCT  420
421   CCAGAATGTC  ACTGCATTAG  GGACGGACAG  TTGGAGCACC  TGCTGGCCCG  GGACCTGGTT  480
481   CCTGGAGACA  CCGTGTGCCT  GTCGGTGGGG  GAGCGGGTCC  CTGCGGATCT  GCGTCTGTAT  540
541   GAGGCGAGCG  ACCTCTCCAT  CGATGAGTCC  AGCCTAACGG  GGGAGACCCA  CCCCAGCTCC  600
601   AAGTCCACGA  CCCCCCAGCC  GCCCGCCTCC  AATGGGAACA  TCGCCTCCCG  CAGCAACATC  660
661   GCCTTCATGG  GGACGCTGGT  TCGCTGCGGC  AAAGCCAAGG  GCATCGTCAT  CGGGACTGGA  720
721   GAGAACTCTG  AGTTCGGGGA  GGTTTTCAAG  ATGATGCAGG  CGGAGGAGGC  TCCTAAGACT  780
781   CCCCTCCAGA  AGAGCATGGA  CCTGCTGGGG  AAGCAGCTGT  CGCTTTACTC  CTTCGGCATC  840
841   ATCGGGGTCA  TCATGCTGGT  GGGCTGGCTG  CAGGGGAAGA  GGATCCTGGA  CATGTTCACT  900
901   ATCGGCGTCA  GCCTGGCGGT  GGCGGCCATC  CCAGAGGGTC  TGCCCATCGT  GGTGACGGTG  960
961   ACGCTGGCGC  TTGGCGTGAT  GCGCATGGTG  AAGAAGAGAG  CCATCGTCAA  GAAACTTCCC  1020
1021  ATCGTGGAGA  CTCTGAGCTG  CTGCAACGTG  ATCTGCTCAG  ACAAGACTGG  AACGCTGACC  1080
1081  AAGAACGAGA  TGACTGTGAC  CCAGGTCTTC  ACCTCAGATG  GACTCCATGC  TGAGGTGACA  1140
1141  GGCGTGGGCT  ACAACGGGAC  CGGAGAGGTG  CTGCTGGACG  GAGAGGTGGT  CCACGGCCTC  1200
1201  GCCTGCCCTT  CCATCAGTAA  AGTTGTGGAG  GTGGGCTGCG  TGTGCAACGA  CTCAATCATC  1260
1261  AGGAACCAGA  ACCTGCTGGG  GCGTCCCACA  GAGGGCGCGC  TCATCGCCCT  CGCCATGAAG  1320
1321  ATGGGTCTGG  AGAGTGTTCA  GCAGGAGTTC  ATCCGTCTGG  AGGAGCATCC  CTTCACCTCC  1380
1381  GAGCAGAAAT  GGATGGCTGT  TCGCTGCGTC  CACCGCACAC  AGCAGGATAA  AAGTGGAGTC  1440
1441  TACTTTATGA  AGGGCGCCTA  TGAGCAGGTG  ATCCGTTTCT  GCAGCAGCTA  CAACAGCAGA  1500
1501  GGCTCCAACC  TTCCCCTGAC  CCACCAGCAG  AGGGAGCTCT  ACCAGCAGCA  GATCAGCTAC  1560
1561  ATGGGCACCT  CAGGCCTCAG  AGTGCTGGCG  TTCGCCTCGG  GTTCCCAGAT  GGGGAGCCTG  1620
1621  ACCTTCCTGG  GCCTGGTGGG  CATCATCGAC  CCGCCCAGGG  AAGGGGTCAA  AGAGGCTGTT  1680
1681  GCTACGCTGC  TCAACTCTGG  GGTCGCCATC  AAGATGATCA  CCGGAGACTC  GCAGGAGACG  1740
1741  GCCGTGTCGA  TAGCGAACCG  TCTGGGCCTC  TACTCCAAAG  GATGCCATTG  TTTGTCAGGA  1800
1801  GAGGAGGTGG  ACCATCTGGA  CCTGCAGGAA  CTGTCCAACA  TCGTTCCTAG  GGTTGGTGTG  1860
1861  TTCTACCGGG  CCAGTCCCAG  ACACAAGCTG  AAGATCGTCA  AGTCTCTCCA  GAACCTCGGT  1920
1921  GCCGTGGTGG  CGATGACTGG  CGACGGCGTA  AATGACGCCG  TGGCGCTGAA  GGCGGCAGAC  1980
1981  ATCGGAGTGG  CGATGGGCAA  GACGGGCACC  GACGTCTGCA  AGGAGGCGGC  GGACATGATC  2040
2041  CTGGTGGACG  ACGACTTCCA  GACCATCATG  TCAGCTATCG  AGGAAGGCAA  AGGAATCTAC  2100
2101  AACAACATCA  AGAACTTTGT  CCGCTTCCAG  CTGAGCACGA  GCATTGCAGC  GCTGACGCTC  2160
2161  ATCTCCCTGG  CAACGCTGAT  GAACTTCCCC  AACCCTCTGA  ACGCCATGCA  GATCCTGTGG  2220
2221  ATCAACATCA  TCATGGACGG  ACCACCCGCT  CAGAGTTTGG  GGGTGGAGCC  TGTGGACCGT  2280
2281  GACGTCATCA  GTAAGCCGCC  TCGCAATGTG  AAGGACACCA  TCCTGACCCG  CAGCCTGCTG  2340
2341  GTCAAGGTCC  TGGTGTCAGC  CTTCATCATT  GTCTGCGGGA  CGCTGTTTGT  CTTTTGGAGA  2400
2401  GAGCTGCAGG  ACAACATGAT  CACTCCTCGA  GACACCACCA  TGACCTTCAC  CTGCTTCGTC  2460
2461  TTCTTCGACA  TGTTCAACGC  TCTGAGCTCG  CGCTCTCAGA  CCCGCATGGT  CCATGAGATG  2520
2521  GGCCTGTGCA  GCAACAGGAC  GTTCTGCTAC  GCCGTCCTGG  CCTCCATCAT  GGGGCAGCTG  2580
2581  CTCGTCATCT  ACTTCCCTCC  ACTGCAGAGC  ATCTTCCAGA  CGGAGAGCCT  CAGCATCCTG  2640
2641  GACCTGCTGT  TCCTGCTCAG  CCTCACCTCC  TCGGTGTGCG  TGGTGTCAGA  GGTCATCAAG  2700
2701  AAGGTGGAGC  GGTGTCGAGG  AGCTGAGCGC  CGCCCCCCCT  CCGACTGCTC  CCTGGAGGTA  2760
2761  TGA  2763

▼ KEYWORD

ID
Family
ATP-binding
Calcium
Calcium transport
Complete proteome
Ion transport
Membrane
Nucleotide-binding
Reference proteome
Transmembrane
Transmembrane helix
Transport

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Integral component of membrane
Molecular Function
ATP binding
Molecular Function
Calcium-transporting ATPase activity
Biological Process
Manganese ion homeostasis
Biological Process
Manganese ion transport

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Pof-0541Poecilia formosa98.690.01704
LLPS-Scm-2595Scophthalmus maximus89.730.01250
LLPS-Orn-0931Oreochromis niloticus89.380.01555
LLPS-Orl-0861Oryzias latipes88.040.01560
LLPS-Ten-1901Tetraodon nigroviridis87.870.01387
LLPS-Scf-1351Scleropages formosus87.130.01499
LLPS-Tar-0169Takifugu rubripes86.750.01528
LLPS-Gaa-0746Gasterosteus aculeatus86.040.01249
LLPS-Leo-2113Lepisosteus oculatus85.530.01498
LLPS-Dar-0453Danio rerio85.160.01484
LLPS-Pes-0443Pelodiscus sinensis83.240.01405
LLPS-Tag-1513Taeniopygia guttata83.150.01407
LLPS-Ora-1982Ornithorhynchus anatinus83.090.01421
LLPS-Mod-2256Monodelphis domestica83.090.01422
LLPS-Gaga-1529Gallus gallus83.090.01409
LLPS-Fia-1728Ficedula albicollis83.040.01405
LLPS-Meg-0937Meleagris gallopavo82.750.01404
LLPS-Xet-0420Xenopus tropicalis82.420.01414
LLPS-Anc-1278Anolis carolinensis82.370.01420
LLPS-Asm-3117Astyanax mexicanus82.350.01399
LLPS-Hos-2267Homo sapiens82.250.01419
LLPS-Ict-0177Ictidomys tridecemlineatus82.250.01417
LLPS-Nol-2650Nomascus leucogenys82.250.01420
LLPS-Gog-2068Gorilla gorilla82.140.01418
LLPS-Pat-1662Pan troglodytes82.140.01418
LLPS-Pap-2119Pan paniscus82.140.01418
LLPS-Caj-2626Callithrix jacchus82.030.01417
LLPS-Chs-1375Chlorocebus sabaeus82.030.01417
LLPS-Maf-2887Macaca fascicularis82.030.01417
LLPS-Cea-1091Cercocebus atys82.030.01417
LLPS-Aim-1606Ailuropoda melanoleuca82.030.01415
LLPS-Mal-2689Mandrillus leucophaeus82.030.01417
LLPS-Paa-2108Papio anubis82.030.01417
LLPS-Orc-0516Oryctolagus cuniculus82.030.01418
LLPS-Fec-0795Felis catus82.030.01412
LLPS-Man-2148Macaca nemestrina82.030.01416
LLPS-Cap-0265Cavia porcellus82.030.01426
LLPS-Poa-0302Pongo abelii82.030.01418
LLPS-Caf-3911Canis familiaris82.030.01413
LLPS-Mam-1546Macaca mulatta82.030.01420
LLPS-Otg-0380Otolemur garnettii81.920.01415
LLPS-Mum-4805Mus musculus81.810.01404
LLPS-Mup-0800Mustela putorius furo81.810.01413
LLPS-Eqc-1166Equus caballus81.810.01412
LLPS-Myl-0981Myotis lucifugus81.70.01402
LLPS-Ran-0892Rattus norvegicus81.490.01389
LLPS-Fud-0978Fukomys damarensis81.480.01416
LLPS-Mea-3757Mesocricetus auratus81.480.01423
LLPS-Tut-1236Tursiops truncatus81.480.01419
LLPS-Bot-2489Bos taurus81.370.01420
LLPS-Aon-2200Aotus nancymaae81.140.01385
LLPS-Loa-0951Loxodonta africana80.940.01416
LLPS-Ova-2937Ovis aries80.830.01423
LLPS-Urm-2751Ursus maritimus80.820.01409
LLPS-Lac-1206Latimeria chalumnae80.780.01323
LLPS-Rhb-1947Rhinopithecus bieti80.690.01402
LLPS-Cas-0152Carlito syrichta79.930.01364
LLPS-Sus-3993Sus scrofa79.270.01390
LLPS-Icp-0679Ictalurus punctatus74.070.01099
LLPS-Anp-3166Anas platyrhynchos66.550.01066
LLPS-Sah-2757Sarcophilus harrisii66.130.01080
LLPS-Cii-0837Ciona intestinalis64.880.01059
LLPS-Dio-4064Dipodomys ordii64.390.01025
LLPS-Cis-0531Ciona savignyi62.820.0 976
LLPS-Cae-1943Caenorhabditis elegans59.20.0 957
LLPS-Drm-1881Drosophila melanogaster57.440.0 934
LLPS-Scj-1503Schizosaccharomyces japonicus54.620.0 798
LLPS-Scp-0372Schizosaccharomyces pombe53.710.0 790
LLPS-Kop-0614Komagataella pastoris52.980.0 788
LLPS-Scc-1445Schizosaccharomyces cryophilus52.10.0 756
LLPS-Abg-0539Absidia glauca51.40.0 726
LLPS-Miv-0269Microbotryum violaceum50.750.0 719
LLPS-Yal-0555Yarrowia lipolytica50.740.0 748
LLPS-Sac-0379Saccharomyces cerevisiae50.230.0 764
LLPS-Tum-0916Tuber melanosporum49.10.0 704
LLPS-Mel-0162Melampsora laricipopulina48.830.0 653
LLPS-Asg-0286Ashbya gossypii48.740.0 737
LLPS-Spr-0632Sporisorium reilianum48.560.0 671
LLPS-Zyt-1381Zymoseptoria tritici47.740.0 682
LLPS-Usm-0913Ustilago maydis47.360.0 652
LLPS-Crn-1382Cryptococcus neoformans46.820.0 674
LLPS-Phn-0948Phaeosphaeria nodorum46.410.0 707
LLPS-Nef-1620Neosartorya fischeri46.20.0 693
LLPS-Cog-0183Colletotrichum gloeosporioides46.00.0 698
LLPS-Fuv-1080Fusarium verticillioides45.810.0 683
LLPS-Pyt-0578Pyrenophora teres45.790.0 708
LLPS-Dos-1314Dothistroma septosporum45.660.0 671
LLPS-Nec-0245Neurospora crassa45.330.0 692
LLPS-Cogr-1003Colletotrichum graminicola45.250.0 701
LLPS-Asni-0437Aspergillus niger45.170.0 695
LLPS-Asn-1062Aspergillus nidulans45.090.0 710
LLPS-Lem-1345Leptosphaeria maculans45.070.0 694
LLPS-Ast-0799Aspergillus terreus45.060.0 697
LLPS-Asc-0701Aspergillus clavatus44.930.0 695
LLPS-Beb-0646Beauveria bassiana44.910.0 678
LLPS-Asf-1057Aspergillus flavus44.90.0 705
LLPS-Aso-0709Aspergillus oryzae44.90.0 705
LLPS-Coo-1527Colletotrichum orbiculare44.870.0 686
LLPS-Pytr-0749Pyrenophora triticirepentis44.840.0 592
LLPS-Asfu-0222Aspergillus fumigatus44.80.0 692
LLPS-Pug-1162Puccinia graminis44.770.0 655
LLPS-Put-0353Puccinia triticina44.510.0 648
LLPS-Gag-1472Gaeumannomyces graminis44.480.0 685
LLPS-Blg-1034Blumeria graminis44.390.0 666
LLPS-Fus-0532Fusarium solani44.390.0 669
LLPS-Mao-1187Magnaporthe oryzae44.180.0 687
LLPS-Ved-1406Verticillium dahliae44.10.0 650
LLPS-Trr-0695Trichoderma reesei43.930.0 690
LLPS-Trv-0570Trichoderma virens43.80.0 683
LLPS-Map-0070Magnaporthe poae43.390.0 684
LLPS-Fuo-1223Fusarium oxysporum43.220.0 598
LLPS-Hov-0438Hordeum vulgare36.222e-120 398
LLPS-Met-1483Medicago truncatula36.125e-129 422
LLPS-Sem-1426Selaginella moellendorffii35.539e-128 418
LLPS-Orbr-1475Oryza brachyantha35.519e-113 377
LLPS-Mae-1551Manihot esculenta35.462e-117 390
LLPS-Zem-2183Zea mays35.434e-113 379
LLPS-Glm-1090Glycine max35.334e-132 431
LLPS-Sob-0876Sorghum bicolor35.21e-114 383
LLPS-Bro-2818Brassica oleracea35.168e-118 392
LLPS-Sot-0914Solanum tuberosum35.088e-116 386
LLPS-Nia-1011Nicotiana attenuata35.072e-119 396
LLPS-Sol-1514Solanum lycopersicum34.991e-115 385
LLPS-Lep-0381Leersia perrieri34.942e-115 385
LLPS-Ors-0878Oryza sativa34.941e-105 353
LLPS-Sei-1223Setaria italica34.931e-112 380
LLPS-Arl-0737Arabidopsis lyrata34.826e-117 389
LLPS-Orm-1550Oryza meridionalis34.781e-114 383
LLPS-Art-2246Arabidopsis thaliana34.74e-118 392
LLPS-Prp-1286Prunus persica34.71e-119 396
LLPS-Orni-0324Oryza nivara34.665e-114 381
LLPS-Orgl-2089Oryza glumaepatula34.665e-114 381
LLPS-Org-1329Oryza glaberrima34.665e-114 381
LLPS-Orr-1838Oryza rufipogon34.667e-114 381
LLPS-Dac-0445Daucus carota34.644e-115 384
LLPS-Gor-0349Gossypium raimondii34.628e-120 397
LLPS-Ori-1744Oryza indica34.554e-112 376
LLPS-Tra-1370Triticum aestivum34.478e-113 378
LLPS-Osl-1393Ostreococcus lucimarinus34.45e-127 416
LLPS-Brn-0528Brassica napus34.353e-107 363
LLPS-Ere-0611Erinaceus europaeus34.352e-122 404
LLPS-Thc-0558Theobroma cacao34.343e-117 390
LLPS-Orb-0171Oryza barthii34.125e-113 379
LLPS-Brd-1759Brachypodium distachyon34.081e-113 380
LLPS-Orp-2205Oryza punctata33.815e-114 380
LLPS-Coc-0254Corchorus capsularis33.763e-112 376
LLPS-Amt-0385Amborella trichopoda33.62e-106 361
LLPS-Gas-0443Galdieria sulphuraria33.122e-115 384
LLPS-Mua-0035Musa acuminata33.03e-113 376
LLPS-Phv-1729Phaseolus vulgaris32.88e-120 397
LLPS-Php-0746Physcomitrella patens32.773e-120 397
LLPS-Viv-2026Vitis vinifera32.552e-118 393
LLPS-Vir-1078Vigna radiata32.216e-115 384
LLPS-Via-1216Vigna angularis32.211e-115 385
LLPS-Hea-0729Helianthus annuus32.181e-115 386
LLPS-Brr-2371Brassica rapa32.187e-119 394
LLPS-Chc-1130Chondrus crispus32.01e-112 376
LLPS-Pot-0858Populus trichocarpa31.775e-115 384
LLPS-Cus-1692Cucumis sativus31.182e-114 382