• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Gog-2068

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Calcium-transporting ATPase
Ensembl Gene: ENSGGOG00000002535.3
Ensembl Protein: ENSGGOP00000036681.1
Organism: Gorilla gorilla
Taxa ID: 9595
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
P-body, Stress granulePredicted from orthologs(View)

▼ FUNCTION

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MDSLLPPSRF  SYFKKYPLHA  IRRYLSTLRN  QRAEEQVARF  QKIPNGENET  MIPVLTSKKA  60
61    SELPVSEVAS  ILQADLQNGL  NKCEVSHRRA  FHGWNEFDIS  EDEPLWKKYI  SQFKNPLIML  120
121   LLASAVISVL  MHQFDDAVSI  TVAILIVVTV  AFVQEYRSEK  SLEELSKLVP  PECHCVREGK  180
181   LEHTLARDLV  PGDTVCLSVG  DRVPADLRLF  EAVDLSIDES  SLTGETTPCS  KVTAPQPAAT  240
241   NGDLASRSNI  AFMGTLVRCG  KAKGVVIGTG  ENSEFGEVFK  MMQAEEAPKT  PLQKSMDLLG  300
301   KQLSFYSFGI  IGIIMLVGWL  LGKDILEMFT  ISVSLAVAAI  PEGLPIVVTV  TLALGVMRMV  360
361   KKRAIVKKLP  IVETLGCCNV  ICSDKTGTLT  KNEMTVTHIF  TSDGLHAEVT  GVGYNQFGEV  420
421   IVDGDVVHGF  YNPAVSRIVE  AGCVCNDAVI  RNNTLMGKPT  EGALIALAMK  MGLDGLQQDY  480
481   IRKAEYPFSS  EQKWMAVKCV  HRTQQDRPEI  CFMKGAYEQV  IKYCTTYQSK  GQTLTLTQQQ  540
541   RDVYQQEKAR  MGSAGLRVLA  LASGPELGQL  TFLGLVGIID  PPRTGVKEAV  TTLIASGVSI  600
601   KMITGDSQET  AVAIASRLGL  YSKTSQSVSG  EEIDAMDVQQ  LSQIVPKVAV  FYRASPRHKM  660
661   KIIKSLQKNG  SVVAMTGDGV  NDAVALKAAD  IGVAMGQTGT  DVCKEAADMI  LVDDDFQTIM  720
721   SAIEEGKGIY  NNIKNFVRFQ  LSTSIAALTL  ISLATLMNFP  NPLNAMQILW  INIIMDGPPA  780
781   QSLGVEPVDK  DVIRKPPRNW  KDSILTKNLI  LKILVSSIII  VCGTLFVFWR  ELRDNVITPR  840
841   DTTMTFTCFV  FFDMFNALSS  RSQTKSVFEI  GLCSNKMFCY  AVLGSIMGQL  LVIYFPPLQK  900
901   VFQTESLSIL  DLLFLLGLTS  SVCIVAEIIK  KVERSREKIQ  KHVWLWERSG  QQLVEIHPHL  960
961   ETGLPLTEDV  SCV  973
Nucleotide CDS Sequence (FASTA)
1     ATGAAGTTGC  ATCAAGTTGC  ACGTTTTCAA  AAAATACCCA  ATGGTGAAAA  TGAGACAATG  60
61    ATTCCTGTAT  TGACATCAAA  AAAAGCAAGT  GAATTACCAG  TTAGTGAAGT  TGCAAGCATT  120
121   CTCCAAGCTG  ATCTTCAGAA  TGGTCTAAAC  AAATGTGAAG  TTAGTCATAG  GCGAGCCTTT  180
181   CATGGCTGGA  ATGAGTTTGA  TATTAGTGAA  GATGAGCCAC  TGTGGAAGAA  GTATATTTCT  240
241   CAGTTTAAAA  ATCCCCTTAT  TATGCTGCTT  CTGGCTTCTG  CAGTCATCAG  TGTTTTAATG  300
301   CATCAGTTTG  ATGATGCCGT  CAGTATCACT  GTGGCAATAC  TTATCGTTGT  TACAGTTGCC  360
361   TTTGTTCAGG  AATATCGTTC  AGAAAAATCT  CTTGAAGAAT  TGAGTAAACT  TGTGCCACCA  420
421   GAATGCCATT  GTGTGCGTGA  AGGAAAATTG  GAGCATACAC  TTGCCCGAGA  CTTGGTTCCA  480
481   GGTGATACAG  TTTGCCTTTC  TGTTGGGGAT  AGAGTTCCTG  CTGACTTACG  CTTGTTTGAG  540
541   GCTGTGGATC  TTTCCATTGA  TGAGTCCAGC  TTGACAGGTG  AGACAACGCC  TTGTTCTAAG  600
601   GTGACAGCTC  CTCAGCCAGC  TGCAACTAAT  GGAGATCTTG  CGTCAAGAAG  TAACATTGCC  660
661   TTTATGGGAA  CACTGGTCAG  ATGTGGCAAA  GCAAAGGGTG  TTGTCATTGG  AACAGGAGAA  720
721   AATTCTGAAT  TTGGGGAGGT  TTTTAAAATG  ATGCAAGCAG  AAGAGGCACC  AAAAACCCCT  780
781   CTGCAGAAGA  GCATGGACCT  CTTAGGAAAA  CAACTTTCCT  TTTACTCCTT  TGGTATAATA  840
841   GGAATCATCA  TGTTGGTTGG  CTGGTTACTG  GGAAAAGATA  TCCTGGAAAT  GTTTACTATT  900
901   AGTGTAAGTT  TGGCTGTAGC  AGCAATTCCT  GAAGGTCTCC  CCATTGTGGT  CACAGTGACG  960
961   CTAGCTCTTG  GTGTCATGAG  AATGGTGAAG  AAAAGGGCCA  TTGTGAAAAA  GCTGCCTATT  1020
1021  GTTGAAACTC  TGGGCTGCTG  TAATGTGATT  TGTTCAGATA  AAACTGGAAC  ACTGACGAAG  1080
1081  AATGAAATGA  CTGTTACTCA  CATATTTACT  TCAGATGGTC  TGCATGCTGA  GGTTACTGGA  1140
1141  GTTGGCTATA  ATCAATTTGG  GGAAGTGATT  GTTGATGGTG  ATGTTGTTCA  TGGATTCTAT  1200
1201  AACCCAGCTG  TTAGCAGAAT  TGTTGAGGCG  GGCTGTGTGT  GCAATGATGC  TGTAATTAGA  1260
1261  AACAATACTC  TAATGGGGAA  GCCAACAGAA  GGGGCCTTAA  TTGCTCTTGC  AATGAAGATG  1320
1321  GGTCTTGATG  GACTTCAACA  AGACTACATC  AGAAAAGCTG  AATACCCTTT  TAGCTCTGAG  1380
1381  CAAAAGTGGA  TGGCTGTTAA  GTGTGTACAC  CGAACACAGC  AGGACAGACC  AGAGATTTGT  1440
1441  TTTATGAAAG  GTGCTTACGA  ACAAGTAATT  AAGTACTGTA  CTACATACCA  GAGCAAAGGG  1500
1501  CAGACCTTGA  CACTTACTCA  GCAGCAGAGA  GATGTGTACC  AACAAGAGAA  GGCACGCATG  1560
1561  GGCTCAGCGG  GACTCAGAGT  TCTTGCTTTG  GCTTCTGGTC  CTGAACTGGG  ACAGCTGACA  1620
1621  TTTCTTGGCT  TGGTGGGAAT  CATTGATCCA  CCTAGAACTG  GTGTGAAAGA  AGCTGTTACA  1680
1681  ACACTCATTG  CCTCAGGAGT  ATCAATAAAA  ATGATTACTG  GAGATTCACA  GGAGACTGCA  1740
1741  GTTGCAATCG  CCAGTCGTCT  GGGATTGTAT  TCCAAAACTT  CCCAGTCAGT  CTCAGGAGAA  1800
1801  GAAATAGATG  CAATGGATGT  TCAGCAGCTT  TCACAAATAG  TACCAAAGGT  TGCAGTATTT  1860
1861  TACAGAGCTA  GCCCAAGGCA  CAAGATGAAA  ATTATTAAGT  CGCTACAGAA  GAATGGTTCA  1920
1921  GTTGTAGCCA  TGACAGGAGA  TGGAGTAAAT  GATGCAGTTG  CTCTGAAGGC  TGCAGACATT  1980
1981  GGAGTTGCGA  TGGGCCAGAC  TGGTACAGAT  GTTTGCAAAG  AGGCAGCAGA  CATGATCCTA  2040
2041  GTGGATGATG  ATTTTCAAAC  CATAATGTCT  GCAATTGAAG  AGGGTAAAGG  GATTTATAAT  2100
2101  AACATTAAAA  ATTTCGTTAG  ATTCCAGCTG  AGCACGAGTA  TAGCAGCATT  AACTTTAATC  2160
2161  TCATTGGCTA  CATTAATGAA  CTTTCCTAAT  CCTCTCAATG  CCATGCAGAT  TTTGTGGATC  2220
2221  AATATTATTA  TGGATGGACC  CCCAGCTCAG  AGCCTTGGAG  TAGAACCAGT  GGATAAAGAT  2280
2281  GTCATTCGTA  AACCTCCTCG  CAACTGGAAA  GACAGCATTT  TGACTAAAAA  CTTGATACTT  2340
2341  AAGATACTTG  TTTCATCAAT  AATCATTGTT  TGTGGGACTT  TGTTTGTCTT  CTGGCGTGAG  2400
2401  CTACGAGACA  ATGTGATTAC  ACCTCGAGAC  ACAACAATGA  CCTTCACATG  CTTTGTGTTT  2460
2461  TTTGACATGT  TCAATGCACT  AAGTTCCAGA  TCCCAGACCA  AGTCTGTGTT  TGAGATTGGA  2520
2521  CTCTGCAGTA  ATAAAATGTT  TTGCTATGCA  GTTCTTGGAT  CCATCATGGG  ACAATTACTA  2580
2581  GTTATTTACT  TTCCTCCGCT  TCAGAAGGTT  TTTCAGACTG  AGAGCCTAAG  CATACTGGAT  2640
2641  CTGTTGTTTC  TTTTGGGTCT  CACCTCATCA  GTGTGCATAG  TGGCAGAAAT  TATAAAGAAG  2700
2701  GTTGAAAGGA  GCAGGGAAAA  GATCCAGAAG  CATGTTAGTT  CGACATCATC  ATCTTTTCTT  2760
2761  GAAGTCTGGC  TCTGGGAGAG  GAGTGGACAG  CAGCTGGTTG  AGATACATCC  CCATCTGGAG  2820
2821  ACAGGACTGC  CACTGACAGA  AGATGTGAGC  TGTGTCTAA  2859

▼ KEYWORD

ID
Family
ATP-binding
Calcium
Calcium transport
Complete proteome
Ion transport
Membrane
Nucleotide-binding
Reference proteome
Transmembrane
Transmembrane helix
Transport

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Golgi membrane
Cellular Component
Integral component of membrane
Cellular Component
Trans-Golgi network
Molecular Function
ATP binding
Molecular Function
Calcium-transporting ATPase activity
Biological Process
Actin cytoskeleton reorganization
Biological Process
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
Biological Process
Epidermis development
Biological Process
Golgi calcium ion homeostasis
Biological Process
Golgi calcium ion transport

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Nol-2650Nomascus leucogenys99.90.01875
LLPS-Hos-2267Homo sapiens99.90.01876
LLPS-Mal-2689Mandrillus leucophaeus99.590.01870
LLPS-Pat-1662Pan troglodytes98.980.01871
LLPS-Pap-2119Pan paniscus98.880.01868
LLPS-Poa-0302Pongo abelii98.730.01791
LLPS-Mam-1546Macaca mulatta98.610.01761
LLPS-Man-2148Macaca nemestrina98.580.01863
LLPS-Paa-2108Papio anubis98.580.01864
LLPS-Maf-2887Macaca fascicularis98.580.01864
LLPS-Cea-1091Cercocebus atys98.580.01864
LLPS-Ova-2937Ovis aries98.570.01710
LLPS-Chs-1375Chlorocebus sabaeus98.520.01788
LLPS-Fud-0978Fukomys damarensis98.520.01785
LLPS-Aim-1606Ailuropoda melanoleuca98.510.01775
LLPS-Caj-2626Callithrix jacchus98.370.01859
LLPS-Cap-0265Cavia porcellus98.30.01783
LLPS-Loa-0951Loxodonta africana98.30.01789
LLPS-Ict-0177Ictidomys tridecemlineatus98.210.01786
LLPS-Bot-2489Bos taurus98.090.01779
LLPS-Mea-3757Mesocricetus auratus97.560.01774
LLPS-Aon-2200Aotus nancymaae97.460.01826
LLPS-Rhb-1947Rhinopithecus bieti97.250.01830
LLPS-Mup-0800Mustela putorius furo97.150.01768
LLPS-Eqc-1166Equus caballus97.050.01838
LLPS-Orc-0516Oryctolagus cuniculus97.050.01838
LLPS-Fec-0795Felis catus96.950.01829
LLPS-Caf-3911Canis familiaris96.940.01762
LLPS-Myl-0981Myotis lucifugus96.910.01742
LLPS-Ran-0892Rattus norvegicus96.70.01668
LLPS-Urm-2751Ursus maritimus96.540.01826
LLPS-Mum-4805Mus musculus96.50.01749
LLPS-Tut-1236Tursiops truncatus95.520.01754
LLPS-Otg-0380Otolemur garnettii95.380.01785
LLPS-Sus-3993Sus scrofa95.330.01739
LLPS-Ora-1982Ornithorhynchus anatinus93.60.01686
LLPS-Pes-0443Pelodiscus sinensis93.50.01607
LLPS-Cas-0152Carlito syrichta93.110.01655
LLPS-Mod-2256Monodelphis domestica92.990.01697
LLPS-Anc-1278Anolis carolinensis92.380.01613
LLPS-Gaga-1529Gallus gallus92.280.01599
LLPS-Fia-1728Ficedula albicollis91.840.01588
LLPS-Tag-1513Taeniopygia guttata89.920.01621
LLPS-Xet-0420Xenopus tropicalis89.120.01526
LLPS-Meg-0937Meleagris gallopavo89.00.01639
LLPS-Leo-2113Lepisosteus oculatus85.790.01509
LLPS-Scf-1351Scleropages formosus84.920.01485
LLPS-Lac-1206Latimeria chalumnae84.60.01431
LLPS-Ten-1901Tetraodon nigroviridis83.540.01325
LLPS-Dar-0453Danio rerio83.20.01447
LLPS-Orn-0931Oreochromis niloticus82.770.01440
LLPS-Pof-0541Poecilia formosa82.370.01433
LLPS-Xim-3263Xiphophorus maculatus82.140.01436
LLPS-Tar-0169Takifugu rubripes82.140.01426
LLPS-Orl-0861Oryzias latipes81.750.01432
LLPS-Asm-3117Astyanax mexicanus81.320.01368
LLPS-Scm-2595Scophthalmus maximus79.840.01145
LLPS-Gaa-0746Gasterosteus aculeatus79.120.01157
LLPS-Icp-0679Ictalurus punctatus70.280.01075
LLPS-Sah-2757Sarcophilus harrisii68.460.01117
LLPS-Anp-3166Anas platyrhynchos66.670.01087
LLPS-Drm-1881Drosophila melanogaster66.262e-115 386
LLPS-Cii-0837Ciona intestinalis65.050.01076
LLPS-Dio-4064Dipodomys ordii63.130.01050
LLPS-Cis-0531Ciona savignyi61.970.01003
LLPS-Cae-1943Caenorhabditis elegans58.80.0 957
LLPS-Kop-0614Komagataella pastoris53.320.0 804
LLPS-Scj-1503Schizosaccharomyces japonicus52.950.0 818
LLPS-Scc-1445Schizosaccharomyces cryophilus52.030.0 776
LLPS-Scp-0372Schizosaccharomyces pombe51.860.0 786
LLPS-Yal-0555Yarrowia lipolytica51.750.0 771
LLPS-Abg-0539Absidia glauca50.790.0 750
LLPS-Sac-0379Saccharomyces cerevisiae49.360.0 782
LLPS-Asg-0286Ashbya gossypii49.310.0 753
LLPS-Mel-0162Melampsora laricipopulina48.890.0 669
LLPS-Miv-0269Microbotryum violaceum48.730.0 723
LLPS-Crn-1382Cryptococcus neoformans48.30.0 709
LLPS-Spr-0632Sporisorium reilianum47.90.0 675
LLPS-Zyt-1381Zymoseptoria tritici47.840.0 716
LLPS-Phn-0948Phaeosphaeria nodorum47.780.0 738
LLPS-Pyt-0578Pyrenophora teres47.520.0 744
LLPS-Tum-0916Tuber melanosporum47.40.0 727
LLPS-Nec-0245Neurospora crassa47.120.0 716
LLPS-Usm-0913Ustilago maydis47.060.0 667
LLPS-Cog-0183Colletotrichum gloeosporioides47.040.0 721
LLPS-Coo-1527Colletotrichum orbiculare47.010.0 713
LLPS-Aso-0709Aspergillus oryzae46.910.0 717
LLPS-Asf-1057Aspergillus flavus46.910.0 717
LLPS-Lem-1345Leptosphaeria maculans46.520.0 726
LLPS-Asn-1062Aspergillus nidulans46.520.0 717
LLPS-Asni-0437Aspergillus niger46.520.0 711
LLPS-Ast-0799Aspergillus terreus46.160.0 728
LLPS-Asc-0701Aspergillus clavatus46.150.0 711
LLPS-Asfu-0222Aspergillus fumigatus46.060.0 701
LLPS-Cogr-1003Colletotrichum graminicola46.00.0 714
LLPS-Nef-1620Neosartorya fischeri45.940.0 702
LLPS-Pytr-0749Pyrenophora triticirepentis45.810.0 637
LLPS-Trv-0570Trichoderma virens45.710.0 704
LLPS-Trr-0695Trichoderma reesei45.70.0 708
LLPS-Fuv-1080Fusarium verticillioides45.60.0 686
LLPS-Ved-1406Verticillium dahliae45.570.0 680
LLPS-Fus-0532Fusarium solani45.560.0 687
LLPS-Put-0353Puccinia triticina45.350.0 652
LLPS-Beb-0646Beauveria bassiana45.270.0 693
LLPS-Dos-1314Dothistroma septosporum45.180.0 705
LLPS-Mao-1187Magnaporthe oryzae44.980.0 704
LLPS-Pug-1162Puccinia graminis44.970.0 660
LLPS-Map-0070Magnaporthe poae44.860.0 716
LLPS-Gag-1472Gaeumannomyces graminis44.80.0 721
LLPS-Blg-1034Blumeria graminis44.70.0 694
LLPS-Fuo-1223Fusarium oxysporum43.320.0 581
LLPS-Sem-1426Selaginella moellendorffii36.277e-132 431
LLPS-Met-1483Medicago truncatula36.191e-132 432
LLPS-Ere-0611Erinaceus europaeus35.968e-129 422
LLPS-Bro-2818Brassica oleracea35.892e-123 409
LLPS-Art-2246Arabidopsis thaliana35.547e-123 407
LLPS-Arl-0737Arabidopsis lyrata35.544e-123 407
LLPS-Sot-0914Solanum tuberosum35.462e-122 405
LLPS-Zem-1889Zea mays35.443e-125 413
LLPS-Sob-0876Sorghum bicolor35.413e-125 413
LLPS-Sei-1223Setaria italica35.416e-123 409
LLPS-Org-0598Oryza glaberrima35.294e-120 399
LLPS-Lep-0381Leersia perrieri35.271e-124 411
LLPS-Nia-1011Nicotiana attenuata35.113e-124 410
LLPS-Amt-0976Amborella trichopoda35.021e-124 412
LLPS-Orbr-1475Oryza brachyantha35.03e-120 399
LLPS-Sol-1514Solanum lycopersicum34.99e-121 401
LLPS-Brn-0528Brassica napus34.836e-114 383
LLPS-Tra-1370Triticum aestivum34.761e-122 406
LLPS-Mae-1551Manihot esculenta34.723e-125 413
LLPS-Orm-1550Oryza meridionalis34.633e-124 410
LLPS-Hea-2442Helianthus annuus34.565e-119 396
LLPS-Pot-0858Populus trichocarpa34.542e-122 406
LLPS-Thc-0558Theobroma cacao34.534e-122 405
LLPS-Orr-1838Oryza rufipogon34.521e-123 409
LLPS-Orgl-2089Oryza glumaepatula34.522e-123 408
LLPS-Orni-0324Oryza nivara34.522e-123 408
LLPS-Brd-1759Brachypodium distachyon34.512e-123 409
LLPS-Viv-2026Vitis vinifera34.53e-122 405
LLPS-Hov-0438Hordeum vulgare34.411e-119 397
LLPS-Ori-1744Oryza indica34.45e-122 404
LLPS-Gor-0349Gossypium raimondii34.393e-125 413
LLPS-Orb-0171Oryza barthii34.285e-120 399
LLPS-Dac-0445Daucus carota34.262e-124 410
LLPS-Coc-0254Corchorus capsularis34.252e-120 400
LLPS-Prp-1286Prunus persica34.244e-124 410
LLPS-Orp-2205Oryza punctata34.114e-116 387
LLPS-Ors-0878Oryza sativa34.067e-117 385
LLPS-Glm-1090Glycine max33.333e-137 446
LLPS-Osl-0337Ostreococcus lucimarinus33.258e-109 367
LLPS-Mua-0035Musa acuminata32.847e-122 400
LLPS-Chc-1130Chondrus crispus32.582e-126 415
LLPS-Php-0746Physcomitrella patens32.454e-126 414
LLPS-Gas-0443Galdieria sulphuraria32.385e-126 414
LLPS-Brr-2371Brassica rapa32.333e-124 410
LLPS-Vir-1078Vigna radiata32.244e-123 407
LLPS-Phv-1729Phaseolus vulgaris32.172e-125 414
LLPS-Via-1216Vigna angularis31.959e-124 409
LLPS-Cus-1692Cucumis sativus31.516e-122 404