• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Xet-0238
pak2

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Non-specific serine/threonine protein kinase
Gene Name: pak2
Ensembl Gene: ENSXETG00000011808.3
Ensembl Protein: ENSXETP00000025827.3
Organism: Xenopus tropicalis
Taxa ID: 8364
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Chromatin, Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSXETT00000025827.3ENSXETP00000025827.3
UniProtF6T2E7, F6T2E7_XENTR
GeneBankAAMC01041485

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSDNGELEDK  PPAPPARISS  TGTKDPLTSN  HSHKPLPLIP  EKPRNKIISM  FSGTEKGSRK  60
61    KERERPEISP  PSDFEHTIHV  GFDAVTGEFT  GMPEQWARLL  QTSNITKLEQ  KKNPQAVLDV  120
121   LKFYDSKHTD  KQKYLSFSAP  DKDGLPSGVS  SAPNAKGSEP  STAATDDDSD  DDKAPPPVIA  180
181   PRPEHTKSMY  TRSVIDPIPP  PPGDSDSAAK  AGDRQKKKTK  MSDEEIMEKL  RTIVSIGDPK  240
241   KKYTRYEKIG  QGASGTVFTA  IDVATGQEVA  IKQINLQKQP  KKELIINEIL  VMKELKNPNI  300
301   VNFLDSFLVS  DELYVVMEYL  AGGSLTDVVT  ETCMDEAQIA  AVCREQCLQA  LEFLHANQVI  360
361   HRDIKSDNVL  LGMDGSVKLT  DFGFCAQITP  EQSKRSTMVG  TPYWMAPEVV  TRKAYGPKVD  420
421   IWSLGIMAIE  MVEGEPPYLN  ENPLRALYLI  ATNGTPELQK  PEKLSPIFRD  FLNRSLEMDV  480
481   EKRGSARELL  QHPFLKLAKP  LSSLTPLILA  AKEAMKGNR  519
Nucleotide CDS Sequence (FASTA)
1     ATGTCTGATA  ACGGGGAGCT  TGAAGATAAG  CCGCCAGCTC  CTCCAGCTCG  GATTAGCAGC  60
61    ACAGGGACAA  AAGATCCTCT  GACCAGCAAC  CACAGTCATA  AACCTTTACC  TTTAATCCCT  120
121   GAAAAACCCA  GGAATAAAAT  TATTTCAATG  TTTTCTGGCA  CAGAAAAAGG  AAGCAGAAAA  180
181   AAAGAAAGGG  AAAGGCCAGA  GATTTCACCA  CCGTCAGATT  TTGAGCACAC  TATTCATGTG  240
241   GGCTTTGATG  CTGTCACTGG  AGAATTCACT  GGAATGCCAG  AGCAATGGGC  ACGGTTACTG  300
301   CAGACCTCAA  ACATTACTAA  ACTCGAACAG  AAGAAAAATC  CACAAGCTGT  CCTGGATGTT  360
361   TTAAAGTTTT  ATGACTCCAA  ACACACAGAC  AAGCAGAAAT  ATCTAAGCTT  CTCTGCACCA  420
421   GATAAAGATG  GGCTTCCCTC  TGGTGTTTCC  TCTGCACCTA  ATGCAAAAGG  CTCTGAACCT  480
481   TCAACAGCAG  CAACAGATGA  TGATAGCGAT  GATGATAAGG  CTCCTCCTCC  TGTTATTGCT  540
541   CCAAGGCCAG  AACACACCAA  ATCAATGTAT  ACACGGTCTG  TAATTGACCC  AATACCTCCA  600
601   CCCCCTGGAG  ATTCAGACAG  TGCTGCAAAG  GCTGGAGACC  GGCAGAAAAA  GAAAACAAAG  660
661   ATGAGCGATG  AAGAGATTAT  GGAAAAACTT  AGAACTATAG  TAAGCATAGG  AGACCCCAAG  720
721   AAAAAATATA  CTAGATATGA  AAAAATTGGA  CAAGGGGCCT  CTGGAACTGT  ATTTACTGCT  780
781   ATTGATGTAG  CTACCGGACA  GGAGGTTGCA  ATCAAACAGA  TAAATCTTCA  GAAGCAGCCC  840
841   AAGAAAGAAC  TGATAATCAA  TGAGATTCTA  GTGATGAAAG  AATTGAAGAA  CCCCAATATA  900
901   GTAAATTTCC  TGGACAGTTT  CTTGGTGAGT  GACGAGCTGT  ATGTTGTAAT  GGAGTATTTG  960
961   GCTGGAGGAT  CCCTTACAGA  CGTAGTCACA  GAAACCTGTA  TGGATGAGGC  ACAGATAGCA  1020
1021  GCTGTCTGCA  GAGAGCAGTG  TCTGCAAGCT  TTGGAATTCC  TACATGCGAA  CCAGGTCATT  1080
1081  CACAGAGACA  TAAAGAGTGA  CAATGTTCTC  CTTGGAATGG  ATGGTTCTGT  CAAACTGACC  1140
1141  GACTTTGGCT  TCTGTGCACA  AATTACCCCA  GAACAGAGCA  AGCGAAGCAC  CATGGTGGGA  1200
1201  ACACCATACT  GGATGGCACC  AGAAGTGGTT  ACAAGGAAAG  CATATGGCCC  CAAGGTGGAT  1260
1261  ATCTGGTCAC  TTGGAATTAT  GGCTATTGAA  ATGGTGGAAG  GGGAACCACC  TTATCTCAAC  1320
1321  GAAAATCCTT  TAAGGGCTTT  GTATTTGATT  GCTACTAATG  GAACTCCGGA  ACTTCAGAAA  1380
1381  CCTGAAAAAC  TTTCACCGAT  ATTCCGGGAT  TTCTTAAACC  GCTCACTTGA  GATGGATGTA  1440
1441  GAAAAGAGAG  GGTCCGCTAG  AGAGCTCTTA  CAGCACCCAT  TCCTGAAACT  CGCAAAACCA  1500
1501  CTGTCCAGCC  TCACACCGCT  AATCCTGGCT  GCCAAAGAAG  CGATGAAGGG  AAACCGCTAA  1560

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Orn-0801Oreochromis niloticus91.210.0 580
LLPS-Gaga-1768Gallus gallus89.670.0 875
LLPS-Gaa-1800Gasterosteus aculeatus89.580.0 570
LLPS-Fia-2834Ficedula albicollis89.290.0 882
LLPS-Anp-1560Anas platyrhynchos88.990.0 885
LLPS-Myl-1884Myotis lucifugus88.390.0 805
LLPS-Tag-1351Taeniopygia guttata88.240.0 888
LLPS-Pes-2866Pelodiscus sinensis87.830.0 859
LLPS-Sah-2884Sarcophilus harrisii87.710.0 808
LLPS-Fud-3575Fukomys damarensis87.50.0 894
LLPS-Ora-0754Ornithorhynchus anatinus87.362e-175 513
LLPS-Mum-0344Mus musculus87.10.0 874
LLPS-Loa-0532Loxodonta africana87.10.0 872
LLPS-Mod-1269Monodelphis domestica87.10.0 875
LLPS-Dar-3495Danio rerio86.980.0 567
LLPS-Ran-3490Rattus norvegicus86.910.0 872
LLPS-Caj-3738Callithrix jacchus86.910.0 874
LLPS-Ict-2594Ictidomys tridecemlineatus86.910.0 874
LLPS-Cas-3118Carlito syrichta86.910.0 875
LLPS-Cap-0915Cavia porcellus86.910.0 895
LLPS-Orc-0413Oryctolagus cuniculus86.910.0 871
LLPS-Otg-2445Otolemur garnettii86.910.0 874
LLPS-Mup-1774Mustela putorius furo86.720.0 872
LLPS-Ova-2601Ovis aries86.720.0 872
LLPS-Bot-1414Bos taurus86.720.0 870
LLPS-Urm-1646Ursus maritimus86.720.0 872
LLPS-Aim-1488Ailuropoda melanoleuca86.530.0 870
LLPS-Fec-0261Felis catus86.530.0 870
LLPS-Aon-2314Aotus nancymaae86.360.0 865
LLPS-Paa-2524Papio anubis86.340.0 870
LLPS-Gog-1425Gorilla gorilla86.340.0 870
LLPS-Cea-3068Cercocebus atys86.340.0 870
LLPS-Maf-3972Macaca fascicularis86.340.0 870
LLPS-Mam-0019Macaca mulatta86.340.0 870
LLPS-Hos-2452Homo sapiens86.340.0 870
LLPS-Sus-2047Sus scrofa86.150.0 866
LLPS-Nol-1055Nomascus leucogenys86.150.0 868
LLPS-Eqc-2134Equus caballus86.150.0 869
LLPS-Pap-1263Pan paniscus86.150.0 870
LLPS-Rhb-0941Rhinopithecus bieti85.970.0 818
LLPS-Caf-2073Canis familiaris85.960.0 865
LLPS-Leo-1380Lepisosteus oculatus85.690.0 863
LLPS-Ten-0447Tetraodon nigroviridis84.590.0 835
LLPS-Scm-0664Scophthalmus maximus84.590.0 850
LLPS-Orl-0513Oryzias latipes84.080.0 831
LLPS-Meg-2382Meleagris gallopavo83.940.0 809
LLPS-Chs-2902Chlorocebus sabaeus83.30.0 832
LLPS-Mea-2754Mesocricetus auratus82.860.0 822
LLPS-Dio-0493Dipodomys ordii82.540.0 830
LLPS-Asm-0227Astyanax mexicanus82.240.0 806
LLPS-Icp-1080Ictalurus punctatus82.040.0 829
LLPS-Poa-0163Pongo abelii81.970.0 810
LLPS-Xim-1519Xiphophorus maculatus81.890.0 830
LLPS-Pof-2228Poecilia formosa81.730.0 825
LLPS-Mal-2942Mandrillus leucophaeus81.020.0 809
LLPS-Drm-2255Drosophila melanogaster80.791e-174 521
LLPS-Tar-2844Takifugu rubripes80.760.0 801
LLPS-Anc-1820Anolis carolinensis80.750.0 811
LLPS-Scf-0208Scleropages formosus77.130.0 757
LLPS-Lac-1238Latimeria chalumnae75.090.0 796
LLPS-Man-0691Macaca nemestrina74.440.0 721
LLPS-Pat-0476Pan troglodytes74.280.0 731
LLPS-Cii-0316Ciona intestinalis73.938e-179 524
LLPS-Tut-2295Tursiops truncatus71.040.0 683
LLPS-Ast-1039Aspergillus terreus66.791e-118 376
LLPS-Abg-0755Absidia glauca66.561e-137 422
LLPS-Cae-1336Caenorhabditis elegans66.474e-156 464
LLPS-Usm-1062Ustilago maydis66.012e-134 416
LLPS-Asn-0596Aspergillus nidulans65.971e-126 397
LLPS-Asni-1574Aspergillus niger65.525e-127 397
LLPS-Phn-0211Phaeosphaeria nodorum65.522e-129 405
LLPS-Lem-0804Leptosphaeria maculans65.422e-130 408
LLPS-Spr-1285Sporisorium reilianum65.022e-131 410
LLPS-Tum-0875Tuber melanosporum64.543e-119 378
LLPS-Asfu-0363Aspergillus fumigatus64.333e-128 400
LLPS-Zyt-0111Zymoseptoria tritici64.291e-131 404
LLPS-Pyt-0362Pyrenophora teres64.071e-128 402
LLPS-Pytr-0173Pyrenophora triticirepentis64.079e-129 402
LLPS-Trv-0879Trichoderma virens64.011e-124 391
LLPS-Nef-0386Neosartorya fischeri64.01e-127 399
LLPS-Asc-1516Aspergillus clavatus63.938e-128 399
LLPS-Sac-0608Saccharomyces cerevisiae63.671e-120 383
LLPS-Put-1135Puccinia triticina63.641e-1790.1
LLPS-Asf-1216Aspergillus flavus63.612e-128 402
LLPS-Aso-1366Aspergillus oryzae63.612e-128 402
LLPS-Dos-1365Dothistroma septosporum63.551e-131 404
LLPS-Miv-1460Microbotryum violaceum63.343e-129 408
LLPS-Mel-1046Melampsora laricipopulina63.192e-125 391
LLPS-Scs-0838Sclerotinia sclerotiorum63.165e-129 400
LLPS-Trr-0785Trichoderma reesei63.129e-128 399
LLPS-Scj-0262Schizosaccharomyces japonicus63.091e-128 398
LLPS-Yal-0672Yarrowia lipolytica62.792e-123 395
LLPS-Gag-1264Gaeumannomyces graminis62.764e-121 385
LLPS-Asg-1412Ashbya gossypii62.22e-117 375
LLPS-Coo-1293Colletotrichum orbiculare61.894e-126 399
LLPS-Fuv-0121Fusarium verticillioides61.563e-124 390
LLPS-Fuo-0431Fusarium oxysporum61.562e-124 390
LLPS-Pug-1422Puccinia graminis61.516e-121 380
LLPS-Blg-1502Blumeria graminis61.443e-126 397
LLPS-Beb-1232Beauveria bassiana61.139e-123 387
LLPS-Crn-0588Cryptococcus neoformans60.982e-123 387
LLPS-Map-1256Magnaporthe poae60.936e-120 383
LLPS-Fus-1143Fusarium solani60.916e-124 390
LLPS-Scc-1216Schizosaccharomyces cryophilus60.871e-123 384
LLPS-Scp-1254Schizosaccharomyces pombe60.825e-123 382
LLPS-Kop-1456Komagataella pastoris60.333e-122 386
LLPS-Cis-0735Ciona savignyi57.660.0 620
LLPS-Cogr-1091Colletotrichum graminicola57.18e-112 358
LLPS-Nec-0592Neurospora crassa56.889e-113 360
LLPS-Mao-1239Magnaporthe oryzae55.561e-109 353