• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Caf-2073
PAK2

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Non-specific serine/threonine protein kinase
Gene Name: PAK2
Ensembl Gene: ENSCAFG00000013067.3
Ensembl Protein: ENSCAFP00000019285.3
Organism: Canis familiaris
Taxa ID: 9615
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Chromatin, Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSDNGELEDK  PPAPPVRMSS  TIFSTGGKDP  LSANHSLKPL  PSVPEEKKPR  NKIISIFSGT  60
61    EKGSKKKEKE  RPEISPPSDF  EHTIHVGFDA  VTGEFTGMPE  QWARLLQTSN  ITKLEQKKNP  120
121   QAVLDVLKFY  DSNTVKQKYL  SFTPTEKDGF  PSGTPTLSAK  GSETAAVVAE  EDDDDEEAAP  180
181   PVIAPRPDHT  KSIYTRSVID  PIPAPVGDSN  VDSGAKSSDK  QKKKTKMTDE  EIMEKLRTIV  240
241   SIGDPKKKYT  RYEKIGQGAS  GTVFTATDVA  LGQEVAIKQI  NLQKQPKKEL  IINEILVMKE  300
301   LKNPNIVNFL  DSYLMGDELF  VVMEYLAGGS  LTDVVTETCM  DEAQIAAVCR  ECLQALEFLH  360
361   ANQVIHRDIK  SDNVLLGMEG  SVKLTDFGFC  AQITPEQSKR  STMVGTPYWM  APEVVTRKAY  420
421   GPKVDIWSLG  IMAIEMIEGE  PPYLNENPLR  ALYLIATNGT  PELQNPEKLS  PIFRDFLNRC  480
481   LEMDVEKRGS  AKELLQHPFL  KLAKPLSSLT  PLIMAAKEAM  KSNR  524
Nucleotide CDS Sequence (FASTA)
1     ATGTCCGATA  ACGGAGAACT  GGAAGACAAG  CCTCCAGCAC  CTCCTGTGCG  AATGAGCAGT  60
61    ACCATTTTTA  GCACTGGAGG  CAAAGATCCT  TTGTCAGCCA  ATCACAGTTT  GAAACCTTTG  120
121   CCCTCCGTTC  CAGAGGAAAA  AAAGCCCAGG  AATAAAATCA  TCTCTATATT  CTCCGGCACA  180
181   GAGAAAGGAA  GTAAGAAGAA  AGAAAAGGAA  CGGCCAGAAA  TTTCTCCTCC  ATCTGATTTT  240
241   GAGCATACCA  TCCATGTTGG  CTTTGATGCG  GTTACGGGAG  AATTTACTGG  CATGCCAGAA  300
301   CAGTGGGCTC  GATTATTACA  GACCTCCAAT  ATCACCAAAC  TAGAGCAAAA  GAAGAATCCT  360
361   CAGGCTGTGC  TGGATGTCTT  AAAGTTCTAT  GACTCCAACA  CAGTGAAGCA  GAAATACCTG  420
421   AGCTTTACTC  CTACTGAGAA  AGATGGCTTC  CCTTCTGGAA  CACCCACACT  GAGTGCCAAG  480
481   GGTTCAGAAA  CAGCAGCAGT  AGTAGCAGAG  GAAGATGATG  ATGATGAAGA  GGCTGCTCCT  540
541   CCTGTTATTG  CCCCACGACC  GGATCATACA  AAATCAATTT  ATACACGGTC  TGTAATTGAC  600
601   CCTATTCCTG  CACCAGTTGG  TGATTCTAAT  GTTGATAGCG  GTGCCAAGTC  TTCTGACAAA  660
661   CAGAAAAAGA  AGACCAAAAT  GACAGATGAA  GAGATTATGG  AAAAATTAAG  AACTATTGTG  720
721   AGCATAGGTG  ACCCTAAGAA  AAAATACACA  AGATACGAAA  AAATTGGGCA  AGGGGCTTCT  780
781   GGTACAGTTT  TCACTGCTAC  TGATGTGGCA  TTGGGACAGG  AGGTTGCTAT  CAAACAGATT  840
841   AATTTACAGA  AACAGCCAAA  GAAGGAATTA  ATCATTAATG  AGATTCTGGT  GATGAAAGAA  900
901   TTAAAGAATC  CCAACATAGT  TAACTTCTTG  GACAGTTACC  TGATGGGAGA  CGAATTGTTT  960
961   GTAGTAATGG  AGTACCTTGC  CGGGGGATCA  CTTACTGATG  TTGTAACAGA  AACCTGCATG  1020
1021  GATGAAGCAC  AGATTGCTGC  TGTATGCAGA  GAGTGTTTAC  AGGCATTGGA  GTTTTTACAT  1080
1081  GCTAATCAAG  TGATCCACAG  AGACATCAAA  AGTGACAACG  TGCTTTTGGG  GATGGAAGGA  1140
1141  TCAGTTAAAC  TTACTGACTT  TGGGTTCTGT  GCCCAGATCA  CCCCTGAGCA  GAGCAAGAGA  1200
1201  AGTACCATGG  TTGGAACGCC  ATACTGGATG  GCACCAGAGG  TGGTTACACG  GAAAGCTTAT  1260
1261  GGCCCTAAAG  TGGACATATG  GTCTCTGGGT  ATCATGGCTA  TTGAGATGAT  AGAAGGAGAG  1320
1321  CCGCCATACC  TCAATGAAAA  TCCCTTGAGG  GCCTTGTACC  TGATAGCAAC  TAATGGAACT  1380
1381  CCAGAACTTC  AGAATCCAGA  GAAGCTTTCC  CCAATATTTC  GGGATTTCTT  AAACCGTTGT  1440
1441  TTGGAGATGG  ATGTGGAGAA  AAGGGGTTCG  GCCAAAGAAT  TATTACAGCA  TCCCTTCCTG  1500
1501  AAACTGGCCA  AACCTTTGTC  CAGCTTGACA  CCACTGATCA  TGGCAGCTAA  AGAAGCAATG  1560
1561  AAGAGTAACC  GTTAG  1575

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Urm-1646Ursus maritimus98.850.0 960
LLPS-Mup-1774Mustela putorius furo98.850.0 960
LLPS-Aim-1488Ailuropoda melanoleuca98.660.0 958
LLPS-Loa-0532Loxodonta africana98.470.0 955
LLPS-Cas-3118Carlito syrichta98.470.0 956
LLPS-Fec-0261Felis catus98.280.0 955
LLPS-Otg-2445Otolemur garnettii98.280.0 956
LLPS-Ict-2594Ictidomys tridecemlineatus98.280.0 957
LLPS-Caj-3738Callithrix jacchus98.090.0 956
LLPS-Orc-0413Oryctolagus cuniculus97.90.0 949
LLPS-Mum-0344Mus musculus97.90.0 955
LLPS-Myl-1884Myotis lucifugus97.80.0 839
LLPS-Ran-3490Rattus norvegicus97.710.0 956
LLPS-Rhb-0941Rhinopithecus bieti97.580.0 896
LLPS-Mam-0019Macaca mulatta97.520.0 950
LLPS-Eqc-2134Equus caballus97.520.0 944
LLPS-Aon-2314Aotus nancymaae97.520.0 946
LLPS-Cea-3068Cercocebus atys97.520.0 950
LLPS-Maf-3972Macaca fascicularis97.520.0 950
LLPS-Paa-2524Papio anubis97.520.0 950
LLPS-Mod-1269Monodelphis domestica97.330.0 952
LLPS-Bot-1414Bos taurus97.330.0 954
LLPS-Cap-0915Cavia porcellus97.140.0 947
LLPS-Nol-1055Nomascus leucogenys97.140.0 949
LLPS-Sah-2884Sarcophilus harrisii97.140.0 843
LLPS-Sus-2047Sus scrofa97.140.0 953
LLPS-Ova-2601Ovis aries97.140.0 952
LLPS-Hos-2452Homo sapiens96.760.0 946
LLPS-Pap-1263Pan paniscus96.560.0 946
LLPS-Gog-1425Gorilla gorilla96.560.0 944
LLPS-Fud-3575Fukomys damarensis96.00.0 948
LLPS-Chs-2902Chlorocebus sabaeus94.470.0 910
LLPS-Anp-1560Anas platyrhynchos93.90.0 920
LLPS-Ora-1470Ornithorhynchus anatinus93.810.0 651
LLPS-Gaga-1768Gallus gallus93.140.0 906
LLPS-Poa-0163Pongo abelii92.940.0 890
LLPS-Dio-0493Dipodomys ordii91.980.0 919
LLPS-Fia-2834Ficedula albicollis91.240.0 896
LLPS-Tag-1351Taeniopygia guttata91.050.0 907
LLPS-Gaa-1800Gasterosteus aculeatus90.850.0 566
LLPS-Pes-2866Pelodiscus sinensis90.10.0 887
LLPS-Mea-2754Mesocricetus auratus90.080.0 879
LLPS-Mal-2942Mandrillus leucophaeus89.690.0 886
LLPS-Meg-2382Meleagris gallopavo87.620.0 839
LLPS-Xet-0238Xenopus tropicalis87.10.0 833
LLPS-Leo-1380Lepisosteus oculatus86.580.0 858
LLPS-Scm-0664Scophthalmus maximus86.040.0 846
LLPS-Man-0691Macaca nemestrina85.690.0 793
LLPS-Orn-3043Oreochromis niloticus85.470.0 839
LLPS-Ten-0447Tetraodon nigroviridis85.280.0 840
LLPS-Orl-0513Oryzias latipes84.020.0 829
LLPS-Anc-1820Anolis carolinensis83.860.0 818
LLPS-Xim-1519Xiphophorus maculatus83.140.0 817
LLPS-Pof-2228Poecilia formosa81.920.0 808
LLPS-Asm-0227Astyanax mexicanus81.80.0 783
LLPS-Icp-1080Ictalurus punctatus81.610.0 822
LLPS-Pat-1809Pan troglodytes81.30.0 742
LLPS-Dar-2099Danio rerio81.080.0 813
LLPS-Scf-0208Scleropages formosus79.890.0 758
LLPS-Tar-2844Takifugu rubripes79.810.0 801
LLPS-Drm-2255Drosophila melanogaster79.593e-169 507
LLPS-Lac-1238Latimeria chalumnae77.840.0 778
LLPS-Cii-0316Ciona intestinalis75.151e-180 529
LLPS-Tut-2295Tursiops truncatus71.710.0 671
LLPS-Cae-1336Caenorhabditis elegans71.033e-147 442
LLPS-Ast-1039Aspergillus terreus68.154e-121 382
LLPS-Abg-0755Absidia glauca67.471e-137 422
LLPS-Asfu-0363Aspergillus fumigatus66.98e-129 402
LLPS-Asc-1516Aspergillus clavatus66.92e-128 401
LLPS-Asni-1574Aspergillus niger66.782e-129 404
LLPS-Put-1135Puccinia triticina66.674e-1788.6
LLPS-Tum-0875Tuber melanosporum66.672e-118 375
LLPS-Asn-0596Aspergillus nidulans66.555e-128 400
LLPS-Aso-1366Aspergillus oryzae66.553e-129 404
LLPS-Asf-1216Aspergillus flavus66.553e-129 404
LLPS-Usm-1062Ustilago maydis66.325e-131 408
LLPS-Spr-1285Sporisorium reilianum65.983e-130 407
LLPS-Coo-1293Colletotrichum orbiculare65.742e-127 403
LLPS-Trr-0785Trichoderma reesei65.622e-128 401
LLPS-Yal-0672Yarrowia lipolytica65.523e-124 397
LLPS-Miv-1460Microbotryum violaceum65.316e-129 408
LLPS-Fus-1143Fusarium solani65.287e-127 398
LLPS-Fuo-0431Fusarium oxysporum65.283e-126 395
LLPS-Trv-0879Trichoderma virens65.281e-126 397
LLPS-Fuv-0121Fusarium verticillioides65.282e-126 396
LLPS-Lem-0804Leptosphaeria maculans64.971e-129 406
LLPS-Sac-0608Saccharomyces cerevisiae64.932e-123 391
LLPS-Beb-1232Beauveria bassiana64.583e-125 394
LLPS-Scs-0838Sclerotinia sclerotiorum64.362e-126 394
LLPS-Gag-1264Gaeumannomyces graminis64.367e-124 393
LLPS-Map-1256Magnaporthe poae64.362e-122 390
LLPS-Phn-0211Phaeosphaeria nodorum64.293e-128 402
LLPS-Dos-1365Dothistroma septosporum64.292e-130 401
LLPS-Zyt-0111Zymoseptoria tritici64.293e-130 401
LLPS-Scj-0262Schizosaccharomyces japonicus64.186e-127 394
LLPS-Pytr-0173Pyrenophora triticirepentis63.951e-128 402
LLPS-Pyt-0362Pyrenophora teres63.952e-128 402
LLPS-Blg-1502Blumeria graminis63.616e-126 396
LLPS-Asg-1412Ashbya gossypii62.984e-119 380
LLPS-Kop-1456Komagataella pastoris62.944e-123 389
LLPS-Mel-1046Melampsora laricipopulina61.91e-119 375
LLPS-Crn-0588Cryptococcus neoformans61.866e-120 378
LLPS-Scc-1216Schizosaccharomyces cryophilus61.354e-121 377
LLPS-Pug-1422Puccinia graminis60.334e-114 362
LLPS-Nef-0386Neosartorya fischeri59.72e-128 401
LLPS-Scp-1254Schizosaccharomyces pombe59.664e-121 377
LLPS-Cogr-1091Colletotrichum graminicola58.311e-110 355
LLPS-Nec-0592Neurospora crassa57.769e-111 355
LLPS-Cis-0735Ciona savignyi57.70.0 595
LLPS-Mao-1239Magnaporthe oryzae57.658e-110 353