DrLLPS - Data resource of LLPS

LLPS-Usm-1129
UMAG_10832

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Profilin
Gene Name:	UMAG_10832
Ensembl Gene:	UMAG_10832
Ensembl Protein:	KIS68732
Organism:	Ustilago maydis
Taxa ID:	237631
LLPS Type:	Client

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Nucleolus	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Homo sapiens	LLPS-Hos-0840	Q8NHR9	Client	Nucleolus	28.70	2e-08	52.8

▼ FUNCTION

Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	KIS68732	KIS68732
UniProt		A0A0D1C4Y2, A0A0D1C4Y2_USTMA
GeneBank	CM003147	KIS68732.1
RefSeq	XM_011391515.1	XP_011389817.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MSWQGYVDTN LVGTGKISQA AIIGLKGGVW ATSSDFNLTA EEQKAIIAGF DDPSGLQAGG 60 61 VRANGKKFFT LGVTPRTIYG KQGGDGLVAV KTNQAVLVCV YMAPIVPGEA NKVAEGLGDY 120 121 LVSVGY 126

▼ KEYWORD

ID	Family
KW-0009	Actin-binding
KW-0181	Complete proteome
KW-0963	Cytoplasm
KW-0206	Cytoskeleton
KW-1185	Reference proteome

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0005938	Cellular Component	Cell cortex
GO:0005856	Cellular Component	Cytoskeleton
GO:0003785	Molecular Function	Actin monomer binding
GO:0042989	Biological Process	Sequestering of actin monomers

▼ KEGG

uma:UMAG_10832

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Spr-0049	Sporisorium reilianum	92.86	9e-81	240
LLPS-Miv-0110	Microbotryum violaceum	57.14	6e-49	159
LLPS-Abg-0846	Absidia glauca	54.76	6e-40	137
LLPS-Pug-0137	Puccinia graminis	53.97	2e-42	142
LLPS-Yal-0168	Yarrowia lipolytica	50.39	5e-35	123
LLPS-Mel-0560	Melampsora laricipopulina	49.59	6e-36	125
LLPS-Scc-0640	Schizosaccharomyces cryophilus	48.82	2e-34	122
LLPS-Scp-0129	Schizosaccharomyces pombe	47.24	4e-33	119
LLPS-Scj-1071	Schizosaccharomyces japonicus	47.24	4e-34	121
LLPS-Dos-0468	Dothistroma septosporum	46.92	1e-32	117
LLPS-Phn-0494	Phaeosphaeria nodorum	46.56	1e-27	105
LLPS-Crn-0412	Cryptococcus neoformans	46.46	8e-34	120
LLPS-Kop-0987	Komagataella pastoris	46.46	2e-33	119
LLPS-Lem-1003	Leptosphaeria maculans	45.8	4e-27	103
LLPS-Asg-1037	Ashbya gossypii	45.67	5e-31	113
LLPS-Sac-0327	Saccharomyces cerevisiae	44.88	5e-31	113
LLPS-Met-2271	Medicago truncatula	44.7	2e-24	96.3
LLPS-Put-0015	Puccinia triticina	44.44	2e-29	109
LLPS-Dac-1353	Daucus carota	43.94	5e-24	95.5
LLPS-Tum-0802	Tuber melanosporum	43.85	4e-26	100
LLPS-Sol-1975	Solanum lycopersicum	43.51	3e-25	98.6
LLPS-Drm-0358	Drosophila melanogaster	42.86	4e-31	113
LLPS-Zyt-0688	Zymoseptoria tritici	42.86	6e-27	103
LLPS-Glm-2392	Glycine max	42.42	1e-22	92.0
LLPS-Hea-2592	Helianthus annuus	42.42	1e-21	89.0
LLPS-Cog-0145	Colletotrichum gloeosporioides	41.98	1e-22	91.7
LLPS-Gor-2263	Gossypium raimondii	41.67	1e-22	91.7
LLPS-Tru-1367	Triticum urartu	41.54	6e-22	90.9
LLPS-Thc-0594	Theobroma cacao	41.54	4e-23	93.2
LLPS-Coc-1194	Corchorus capsularis	41.35	1e-23	94.7
LLPS-Sob-0471	Sorghum bicolor	41.22	2e-22	90.9
LLPS-Amt-2225	Amborella trichopoda	41.22	5e-24	95.5
LLPS-Zem-1186	Zea mays	41.22	8e-22	89.7
LLPS-Cus-1204	Cucumis sativus	40.77	4e-22	90.5
LLPS-Arl-2743	Arabidopsis lyrata	40.77	4e-21	87.8
LLPS-Nec-0514	Neurospora crassa	40.6	3e-24	95.9
LLPS-Gas-0097	Galdieria sulphuraria	40.48	1e-27	104
LLPS-Sem-2040	Selaginella moellendorffii	40.15	3e-21	88.2
LLPS-Orbr-2197	Oryza brachyantha	40.0	7e-21	87.0
LLPS-Mae-1208	Manihot esculenta	40.0	3e-23	93.2
LLPS-Nia-1270	Nicotiana attenuata	40.0	1e-21	89.4
LLPS-Pytr-1200	Pyrenophora triticirepentis	40.0	2e-22	91.3
LLPS-Bro-1932	Brassica oleracea	40.0	4e-21	88.6
LLPS-Art-2893	Arabidopsis thaliana	39.85	3e-21	88.2
LLPS-Beb-0163	Beauveria bassiana	39.69	2e-23	94.0
LLPS-Fuv-0520	Fusarium verticillioides	39.69	1e-20	86.3
LLPS-Sei-0727	Setaria italica	39.69	4e-21	87.8
LLPS-Pyt-0975	Pyrenophora teres	39.23	3e-22	90.9
LLPS-Lep-0760	Leersia perrieri	39.23	4e-22	90.5
LLPS-Brd-2155	Brachypodium distachyon	39.23	1e-20	86.3
LLPS-Cym-0364	Cyanidioschyzon merolae	39.06	2e-23	95.5
LLPS-Viv-2521	Vitis vinifera	38.93	6e-22	89.7
LLPS-Fus-0813	Fusarium solani	38.93	2e-20	85.9
LLPS-Fuo-0375	Fusarium oxysporum	38.93	2e-20	85.9
LLPS-Tra-1606	Triticum aestivum	38.93	4e-22	90.5
LLPS-Gag-1091	Gaeumannomyces graminis	38.17	3e-19	82.8
LLPS-Php-0499	Physcomitrella patens	38.17	7e-18	79.3
LLPS-Mua-0506	Musa acuminata	38.17	6e-21	87.4
LLPS-Mao-0219	Magnaporthe oryzae	38.17	4e-21	87.8
LLPS-Map-0061	Magnaporthe poae	37.4	2e-18	80.5
LLPS-Ors-1388	Oryza sativa	36.92	8e-20	84.3
LLPS-Orp-0970	Oryza punctata	36.92	5e-20	84.7
LLPS-Orr-0341	Oryza rufipogon	36.92	8e-20	84.3
LLPS-Orm-1864	Oryza meridionalis	36.92	8e-20	84.3
LLPS-Org-0964	Oryza glaberrima	36.92	8e-20	84.3
LLPS-Orb-2103	Oryza barthii	36.92	8e-20	84.3
LLPS-Ori-1858	Oryza indica	36.92	8e-20	84.3
LLPS-Orni-1355	Oryza nivara	36.92	8e-20	84.3
LLPS-Blg-0039	Blumeria graminis	36.43	1e-20	86.7
LLPS-Cogr-0954	Colletotrichum graminicola	35.88	5e-17	77.0
LLPS-Asni-0127	Aspergillus niger	35.83	3e-19	83.2
LLPS-Asfu-0404	Aspergillus fumigatus	35.2	7e-15	71.2
LLPS-Ved-0294	Verticillium dahliae	34.71	3e-10	58.5
LLPS-Coo-1096	Colletotrichum orbiculare	34.65	3e-14	70.1
LLPS-Ast-0200	Aspergillus terreus	34.62	8e-11	59.7
LLPS-Asf-0926	Aspergillus flavus	34.43	5e-20	85.1
LLPS-Trv-0456	Trichoderma virens	34.35	2e-16	75.5
LLPS-Chr-0531	Chlamydomonas reinhardtii	34.33	2e-14	69.7
LLPS-Asn-1046	Aspergillus nidulans	32.5	2e-15	72.4
LLPS-Nef-1322	Neosartorya fischeri	32.43	2e-10	58.5
LLPS-Trr-0086	Trichoderma reesei	32.06	2e-14	70.1
LLPS-Asc-0147	Aspergillus clavatus	31.53	4e-09	54.7
LLPS-Leo-1674	Lepisosteus oculatus	31.03	7e-11	60.1
LLPS-Aso-1011	Aspergillus oryzae	30.95	1e-13	67.4
LLPS-Pes-0033	Pelodiscus sinensis	30.77	2e-10	58.5
LLPS-Cap-0564	Cavia porcellus	30.43	1e-08	53.9
LLPS-Mod-1907	Monodelphis domestica	29.17	2e-10	58.5
LLPS-Pap-0217	Pan paniscus	28.7	2e-08	52.8
LLPS-Pat-1084	Pan troglodytes	28.7	2e-08	52.8
LLPS-Hos-0840	Homo sapiens	28.7	2e-08	52.8
LLPS-Poa-1207	Pongo abelii	28.7	3e-08	52.8
LLPS-Gog-0558	Gorilla gorilla	28.7	4e-08	52.4
LLPS-Rhb-0413	Rhinopithecus bieti	27.83	1e-07	50.8
LLPS-Mum-3477	Mus musculus	27.83	8e-07	48.5
LLPS-Ran-0157	Rattus norvegicus	27.83	5e-06	46.2
LLPS-Ict-3219	Ictidomys tridecemlineatus	27.59	1e-07	50.8
LLPS-Lac-0815	Latimeria chalumnae	27.42	1e-12	65.1
LLPS-Dar-2442	Danio rerio	26.96	4e-08	52.0
LLPS-Man-1613	Macaca nemestrina	26.96	7e-07	48.5
LLPS-Mam-0604	Macaca mulatta	26.96	7e-07	48.5
LLPS-Maf-1182	Macaca fascicularis	26.96	7e-07	48.5
LLPS-Chs-2630	Chlorocebus sabaeus	26.96	7e-07	48.5
LLPS-Cea-0658	Cercocebus atys	26.96	7e-07	48.5
LLPS-Caj-2755	Callithrix jacchus	26.96	7e-06	45.8
LLPS-Mal-0464	Mandrillus leucophaeus	26.96	7e-07	48.5
LLPS-Ova-1010	Ovis aries	26.96	9e-07	48.1
LLPS-Gaga-3645	Gallus gallus	26.77	3e-07	49.7
LLPS-Ora-1190	Ornithorhynchus anatinus	26.67	6e-08	51.6
LLPS-Nol-2350	Nomascus leucogenys	26.13	3e-06	46.6
LLPS-Aon-1678	Aotus nancymaae	26.09	1e-06	47.8
LLPS-Bot-1927	Bos taurus	26.09	5e-06	46.2
LLPS-Mup-3978	Mustela putorius furo	26.09	2e-06	47.4
LLPS-Orc-2824	Oryctolagus cuniculus	25.23	4e-06	46.2

LLPS-Usm-1129UMAG_10832

Protein Sequence

Nucleotide Sequence

LLPS-Usm-1129
UMAG_10832