DrLLPS - Data resource of LLPS

LLPS-Usm-0709
MRD1

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Multiple RNA-binding domain-containing protein 1
Gene Name:	MRD1, UMAG_02346
Ensembl Gene:	UMAG_02346
Ensembl Protein:	KIS69825
Organism:	Ustilago maydis
Taxa ID:	237631
LLPS Type:	Others

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Nucleolus, P-body	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Bos taurus	LLPS-Bot-0001		Client	Nucleolus	52.44	3e-11	71.6
Homo sapiens	LLPS-Hos-2152	Q9Y4C8	Client	Nucleolus, P-body	37.15	7e-105	353
Mus musculus	LLPS-Mum-1173	Q8R3C6	Client	Nucleolus	51.22	1e-10	70.1
Arabidopsis thaliana	LLPS-Art-0344	F4JT92	Client	Nucleolus	40.66	2e-26	120

▼ FUNCTION

Involved in pre-rRNA processing.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	KIS69825	KIS69825
UniProt		Q4PC17, MRD1_USTMA, A0A0D1E600
GeneBank	CM003144	KIS69825.1
RefSeq	XM_011390355.1	XP_011388657.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MSRLIVRGLP SYLTDARLRE HFSQKGAVTD VKLMRRPDGT SRKFGFVGYR SEQEAQQALD 60 61 YFNRTFIDTS RISIELAKKI GDEELVHQRE ERRNRRNAGA GPEGSASTSD ARKRKADKSD 120 121 TQQEEGSGKK KPKKGGAISF EEFMSVMQPK AKRKAWQNED ALPEQTMQDI VAPEEAIQKK 180 181 AARKALKKAD AAAAATATAE STAAQPDSGR EETPEPDAAA NDVGLTDEEY MRLRMKHRVG 240 241 TDLDTLEQSS SGPEFEQSDN EKDDDDAAAD SDPESEDEPI HDQGFECKQA EMQRKAQQAA 300 301 EKDQKLVDQI MESGRLFIRN LPFAASGDEI LAFFESFGTV KQVHIPLDKQ TKASKGLAFV 360 361 SFSDPAHALA AYRAKDGSTF QGRLLHLLPA VNKDALAETG SKKTATLKQA RAEQKKQDAT 420 421 KDFNWSMLYM SSDAVASSIA DRLGVNKSDI LNPGANGGAD NAAVRLALAE TRIIQETKEF 480 481 LAQQGINVDA FQGAKGPRSD TTILVKNIPY GTSAEEVEKL FGEHGEVDKV LIPPSGTIAV 540 541 VEMPVVNEAR LAFRAIAYKR FKGGILYLEK APVGLLTQHK VGEKVVKQAP IVGKSIDSSN 600 601 PSVDLDGPAG AGAGDEAVDG ATLYVKNLSF STTDERLTAF FHGLSDFAFA RIQTKPDPRR 660 661 PGARLSMGYG FVGFKSIDAA RTAQKAMDGK VLDAHTLVVT FARRNAEAST TSISSGGSTK 720 721 ILIKNLPFEA TKRDIRDLFS SQGQLKSVRL PKKFDNTTRG FGFVEYSTVR EAQSAMEALK 780 781 HTHLLGRHLV LQWSHLASST QQQVDMQRSK TKQHFVNTHD NAARADPSKR AKIKLNSAQI 840 841 SEAIKQAKRQ RDDVDDDE 858

Protein Sequence (FASTA)

1     MSRLIVRGLP  SYLTDARLRE  HFSQKGAVTD  VKLMRRPDGT  SRKFGFVGYR  SEQEAQQALD  60
61    YFNRTFIDTS  RISIELAKKI  GDEELVHQRE  ERRNRRNAGA  GPEGSASTSD  ARKRKADKSD  120
121   TQQEEGSGKK  KPKKGGAISF  EEFMSVMQPK  AKRKAWQNED  ALPEQTMQDI  VAPEEAIQKK  180
181   AARKALKKAD  AAAAATATAE  STAAQPDSGR  EETPEPDAAA  NDVGLTDEEY  MRLRMKHRVG  240
241   TDLDTLEQSS  SGPEFEQSDN  EKDDDDAAAD  SDPESEDEPI  HDQGFECKQA  EMQRKAQQAA  300
301   EKDQKLVDQI  MESGRLFIRN  LPFAASGDEI  LAFFESFGTV  KQVHIPLDKQ  TKASKGLAFV  360
361   SFSDPAHALA  AYRAKDGSTF  QGRLLHLLPA  VNKDALAETG  SKKTATLKQA  RAEQKKQDAT  420
421   KDFNWSMLYM  SSDAVASSIA  DRLGVNKSDI  LNPGANGGAD  NAAVRLALAE  TRIIQETKEF  480
481   LAQQGINVDA  FQGAKGPRSD  TTILVKNIPY  GTSAEEVEKL  FGEHGEVDKV  LIPPSGTIAV  540
541   VEMPVVNEAR  LAFRAIAYKR  FKGGILYLEK  APVGLLTQHK  VGEKVVKQAP  IVGKSIDSSN  600
601   PSVDLDGPAG  AGAGDEAVDG  ATLYVKNLSF  STTDERLTAF  FHGLSDFAFA  RIQTKPDPRR  660
661   PGARLSMGYG  FVGFKSIDAA  RTAQKAMDGK  VLDAHTLVVT  FARRNAEAST  TSISSGGSTK  720
721   ILIKNLPFEA  TKRDIRDLFS  SQGQLKSVRL  PKKFDNTTRG  FGFVEYSTVR  EAQSAMEALK  780
781   HTHLLGRHLV  LQWSHLASST  QQQVDMQRSK  TKQHFVNTHD  NAARADPSKR  AKIKLNSAQI  840
841   SEAIKQAKRQ  RDDVDDDE  858

▼ KEYWORD

ID	Family
KW-0181	Complete proteome
KW-0539	Nucleus
KW-1185	Reference proteome
KW-0677	Repeat
KW-0687	Ribonucleoprotein
KW-0694	RNA-binding
KW-0698	rRNA processing

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0016607	Cellular Component	Nuclear speck
GO:0005730	Cellular Component	Nucleolus
GO:0003723	Molecular Function	RNA binding
GO:0045292	Biological Process	MRNA cis splicing, via spliceosome
GO:0000381	Biological Process	Regulation of alternative mRNA splicing, via spliceosome
GO:0006364	Biological Process	RRNA processing

▼ KEGG

uma:UMAG_02346

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Spr-0077	Sporisorium reilianum	79.2	0.0	1202
LLPS-Bro-1414	Brassica oleracea	55.42	3e-23	110
LLPS-Cym-0299	Cyanidioschyzon merolae	55.26	6e-16	86.7
LLPS-Gaga-0584	Gallus gallus	54.88	4e-20	100
LLPS-Tag-0521	Taeniopygia guttata	54.88	3e-20	100
LLPS-Brr-1824	Brassica rapa	54.88	5e-22	106
LLPS-Brn-2660	Brassica napus	54.88	2e-22	108
LLPS-Osl-0161	Ostreococcus lucimarinus	54.43	6e-20	99.8
LLPS-Cas-0961	Carlito syrichta	53.66	3e-20	100
LLPS-Eqc-0389	Equus caballus	53.66	1e-19	99.0
LLPS-Fia-2644	Ficedula albicollis	53.66	8e-20	99.4
LLPS-Mea-0949	Mesocricetus auratus	53.66	8e-20	99.4
LLPS-Ova-1337	Ovis aries	52.44	1e-19	99.0
LLPS-Kop-0702	Komagataella pastoris	52.44	5e-20	99.8
LLPS-Bot-0001	Bos taurus	52.44	2e-19	98.6
LLPS-Asg-0072	Ashbya gossypii	51.65	2e-19	97.8
LLPS-Otg-0303	Otolemur garnettii	51.22	4e-19	97.1
LLPS-Myl-3655	Myotis lucifugus	51.22	2e-19	98.2
LLPS-Pof-0087	Poecilia formosa	50.0	4e-18	94.0
LLPS-Tar-1472	Takifugu rubripes	50.0	1e-17	92.4
LLPS-Scf-2647	Scleropages formosus	50.0	3e-16	88.2
LLPS-Chr-0460	Chlamydomonas reinhardtii	48.81	8e-20	99.8
LLPS-Scm-1219	Scophthalmus maximus	48.78	8e-18	92.8
LLPS-Anp-2292	Anas platyrhynchos	48.75	2e-15	84.7
LLPS-Chc-0211	Chondrus crispus	48.15	4e-17	90.5
LLPS-Nec-0079	Neurospora crassa	47.73	1e-15	85.9
LLPS-Coo-0197	Colletotrichum orbiculare	47.06	1e-14	82.4
LLPS-Mel-1077	Melampsora laricipopulina	46.89	2e-140	434
LLPS-Cogr-0030	Colletotrichum graminicola	45.98	1e-14	82.4
LLPS-Cog-0801	Colletotrichum gloeosporioides	45.88	4e-14	80.9
LLPS-Yal-1020	Yarrowia lipolytica	45.65	2e-15	85.5
LLPS-Scj-0240	Schizosaccharomyces japonicus	45.63	2e-129	414
LLPS-Met-0632	Medicago truncatula	45.57	2e-08	62.4
LLPS-Fus-0184	Fusarium solani	45.35	6e-119	387
LLPS-Beb-0382	Beauveria bassiana	45.35	2e-13	78.6
LLPS-Drm-1236	Drosophila melanogaster	45.24	5e-16	87.0
LLPS-Asm-2980	Astyanax mexicanus	45.12	2e-15	85.1
LLPS-Fuv-0408	Fusarium verticillioides	44.95	7e-118	385
LLPS-Trv-0553	Trichoderma virens	44.94	9e-120	390
LLPS-Fuo-0827	Fusarium oxysporum	44.75	1e-117	385
LLPS-Trr-1090	Trichoderma reesei	44.65	2e-119	387
LLPS-Scc-1402	Schizosaccharomyces cryophilus	44.03	6e-130	416
LLPS-Pytr-0776	Pyrenophora triticirepentis	43.98	1e-114	375
LLPS-Ved-0277	Verticillium dahliae	43.86	3e-116	381
LLPS-Dos-0707	Dothistroma septosporum	43.75	1e-12	76.3
LLPS-Zyt-0733	Zymoseptoria tritici	43.69	5e-117	380
LLPS-Asfu-0217	Aspergillus fumigatus	43.37	7e-120	390
LLPS-Sol-0929	Solanum lycopersicum	43.37	3e-30	132
LLPS-Nef-0633	Neosartorya fischeri	43.17	2e-118	386
LLPS-Asc-0312	Aspergillus clavatus	42.77	5e-118	385
LLPS-Crn-0049	Cryptococcus neoformans	42.73	4e-124	399
LLPS-Abg-0800	Absidia glauca	42.59	1e-122	395
LLPS-Ast-0306	Aspergillus terreus	42.55	2e-117	383
LLPS-Coc-0935	Corchorus capsularis	42.44	2e-55	206
LLPS-Pyt-0273	Pyrenophora teres	42.42	2e-116	380
LLPS-Asf-0781	Aspergillus flavus	42.37	2e-115	378
LLPS-Aso-0316	Aspergillus oryzae	42.37	2e-115	377
LLPS-Asn-0516	Aspergillus nidulans	42.35	4e-115	377
LLPS-Mao-0428	Magnaporthe oryzae	42.35	1e-12	76.3
LLPS-Via-0022	Vigna angularis	41.54	5e-16	87.0
LLPS-Miv-0790	Microbotryum violaceum	41.46	3e-130	416
LLPS-Sem-0549	Selaginella moellendorffii	41.38	7e-11	70.5
LLPS-Hov-1199	Hordeum vulgare	41.36	4e-23	110
LLPS-Ten-0736	Tetraodon nigroviridis	40.74	1e-63	223
LLPS-Scp-0429	Schizosaccharomyces pombe	40.64	2e-124	402
LLPS-Prp-0171	Prunus persica	39.74	2e-98	332
LLPS-Art-1123	Arabidopsis thaliana	39.74	7e-09	63.9
LLPS-Arl-1536	Arabidopsis lyrata	39.74	7e-09	63.5
LLPS-Chs-1218	Chlorocebus sabaeus	39.58	3e-59	223
LLPS-Hea-0391	Helianthus annuus	39.38	3e-26	119
LLPS-Tru-0396	Triticum urartu	39.24	1e-23	111
LLPS-Org-1002	Oryza glaberrima	39.24	4e-24	113
LLPS-Orm-0909	Oryza meridionalis	39.24	5e-24	113
LLPS-Orr-0364	Oryza rufipogon	39.24	3e-24	113
LLPS-Orgl-0729	Oryza glumaepatula	39.24	3e-24	113
LLPS-Ori-0106	Oryza indica	39.24	4e-24	113
LLPS-Orb-2066	Oryza barthii	39.24	3e-24	113
LLPS-Mae-0749	Manihot esculenta	38.99	7e-27	121
LLPS-Php-0326	Physcomitrella patens	38.92	1e-25	117
LLPS-Dio-0721	Dipodomys ordii	38.89	3e-20	100
LLPS-Cae-0978	Caenorhabditis elegans	38.7	2e-52	201
LLPS-Tra-0799	Triticum aestivum	38.61	2e-23	110
LLPS-Gas-0771	Galdieria sulphuraria	38.61	8e-26	118
LLPS-Glm-0481	Glycine max	38.6	2e-91	313
LLPS-Zem-0638	Zea mays	38.51	1e-22	108
LLPS-Sob-1803	Sorghum bicolor	38.42	4e-23	109
LLPS-Pot-0117	Populus trichocarpa	38.36	5e-27	122
LLPS-Sah-1091	Sarcophilus harrisii	38.36	1e-21	105
LLPS-Pug-0219	Puccinia graminis	38.35	2e-141	444
LLPS-Phv-2298	Phaseolus vulgaris	38.3	2e-08	61.2
LLPS-Fec-1763	Felis catus	38.27	8e-21	102
LLPS-Vir-1195	Vigna radiata	38.2	2e-93	319
LLPS-Mua-0631	Musa acuminata	38.14	3e-92	315
LLPS-Amt-0084	Amborella trichopoda	38.1	9e-99	329
LLPS-Cus-0898	Cucumis sativus	38.1	3e-24	113
LLPS-Put-0307	Puccinia triticina	38.07	1e-147	464
LLPS-Mod-1471	Monodelphis domestica	37.74	5e-21	103
LLPS-Viv-0479	Vitis vinifera	37.72	2e-100	337
LLPS-Leo-3410	Lepisosteus oculatus	37.71	9e-93	319
LLPS-Orbr-0275	Oryza brachyantha	37.5	3e-20	100
LLPS-Cii-0089	Ciona intestinalis	37.5	1e-10	69.3
LLPS-Orc-2489	Oryctolagus cuniculus	37.45	2e-90	313
LLPS-Xet-1669	Xenopus tropicalis	37.35	2e-19	98.2
LLPS-Lem-0831	Leptosphaeria maculans	37.35	3e-135	431
LLPS-Caj-0622	Callithrix jacchus	37.34	6e-95	325
LLPS-Aon-2775	Aotus nancymaae	37.29	9e-97	330
LLPS-Sus-3394	Sus scrofa	37.15	3e-92	318
LLPS-Dar-1974	Danio rerio	37.09	6e-89	308
LLPS-Mup-0121	Mustela putorius furo	37.04	7e-21	102
LLPS-Fud-1101	Fukomys damarensis	37.04	6e-20	99.8
LLPS-Sei-0085	Setaria italica	37.03	4e-89	308
LLPS-Mam-0578	Macaca mulatta	36.97	9e-21	102
LLPS-Man-3569	Macaca nemestrina	36.97	6e-21	102
LLPS-Maf-1513	Macaca fascicularis	36.97	9e-21	102
LLPS-Orl-1270	Oryzias latipes	36.84	7e-92	316
LLPS-Gaa-0342	Gasterosteus aculeatus	36.81	2e-92	318
LLPS-Xim-1125	Xiphophorus maculatus	36.8	1e-92	319
LLPS-Nia-1442	Nicotiana attenuata	36.78	3e-139	441
LLPS-Cea-0987	Cercocebus atys	36.78	3e-97	332
LLPS-Rhb-3036	Rhinopithecus bieti	36.6	1e-95	328
LLPS-Paa-0469	Papio anubis	36.6	3e-96	330
LLPS-Sot-0200	Solanum tuberosum	36.59	4e-139	441
LLPS-Lep-1009	Leersia perrieri	36.53	1e-83	295
LLPS-Caf-2201	Canis familiaris	36.48	5e-92	317
LLPS-Poa-2987	Pongo abelii	36.48	2e-20	101
LLPS-Pes-1542	Pelodiscus sinensis	36.45	2e-93	320
LLPS-Ran-0084	Rattus norvegicus	36.42	7e-19	96.3
LLPS-Mum-1173	Mus musculus	36.42	4e-20	100
LLPS-Nol-1914	Nomascus leucogenys	36.41	9e-96	328
LLPS-Gog-2568	Gorilla gorilla	36.41	1e-95	327
LLPS-Tum-0282	Tuber melanosporum	36.39	3e-102	341
LLPS-Hos-2152	Homo sapiens	36.36	7e-20	99.8
LLPS-Pap-1019	Pan paniscus	36.36	7e-20	99.8
LLPS-Pat-0349	Pan troglodytes	36.36	7e-20	99.8
LLPS-Aim-2168	Ailuropoda melanoleuca	36.36	9e-21	102
LLPS-Phn-0114	Phaeosphaeria nodorum	36.34	2e-140	444
LLPS-Urm-0504	Ursus maritimus	36.31	2e-92	319
LLPS-Scs-0197	Sclerotinia sclerotiorum	36.22	6e-143	451
LLPS-Icp-0000	Ictalurus punctatus	36.0	3e-92	317
LLPS-Orni-0774	Oryza nivara	35.9	2e-85	294
LLPS-Blg-0455	Blumeria graminis	35.89	1e-139	441
LLPS-Gag-0223	Gaeumannomyces graminis	35.89	2e-139	442
LLPS-Orn-0301	Oreochromis niloticus	35.85	2e-88	307
LLPS-Ors-1600	Oryza sativa	35.85	8e-85	287
LLPS-Mal-1567	Mandrillus leucophaeus	35.85	7e-20	99.4
LLPS-Anc-0058	Anolis carolinensis	35.66	1e-91	317
LLPS-Sac-0956	Saccharomyces cerevisiae	35.25	7e-105	351
LLPS-Map-0425	Magnaporthe poae	35.13	1e-132	424
LLPS-Cap-0482	Cavia porcellus	35.11	9e-88	306
LLPS-Loa-0203	Loxodonta africana	34.59	3e-20	100
LLPS-Thc-1269	Theobroma cacao	34.48	5e-132	426
LLPS-Orp-0175	Oryza punctata	34.27	4e-66	239
LLPS-Asni-0870	Aspergillus niger	33.97	5e-134	427
LLPS-Dac-0550	Daucus carota	33.61	4e-118	384
LLPS-Meg-0157	Meleagris gallopavo	33.54	4e-15	84.3
LLPS-Gor-1673	Gossypium raimondii	33.41	1e-132	424
LLPS-Lac-0325	Latimeria chalumnae	33.33	2e-69	248
LLPS-Brd-0610	Brachypodium distachyon	32.51	4e-117	384

LLPS-Usm-0709MRD1

Protein Sequence

Nucleotide Sequence

LLPS-Usm-0709
MRD1