LLPS-Mum-1173
Rbm19

▼ OVERVIEW

Status: Reviewed
Protein Name: Probable RNA-binding protein 19; RNA-binding motif protein 19
Gene Name: Rbm19
Ensembl Gene: ENSMUSG00000029594.12
Ensembl Protein: ENSMUSP00000144339.1
Organism: Mus musculus
Taxa ID: 10090
LLPS Type: Others
PDB: 1WHW (A) More


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateDescriptionTissue/CellPMIDs
P-bodyPredicted from orthologsN/A(View)

▼ FUNCTION

Plays a role in embryo pre-implantation development.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSRLIVKNLP  NGMKEERFRQ  LFAAFGTLTD  CSLKFTKDGK  FRKFGFIGFK  SEEEAQAALN  60
61    HFHRSFIDTT  RITVEFCKSF  GDPSKPRAWS  KHAQKSSQPK  QPSQDSVPSD  TKKDKKKKGP  120
121   SDLEKLKEDA  KFQEFLSIHQ  KRTQVATWAN  DALEAKLPKA  KTKASSDYLN  FDSDSNSDSG  180
181   QESEEEPARE  DPEEEQGLQP  KAAVQKELSD  MDYLKSKMVR  AEVSSEDEDE  EDSEDEAVNC  240
241   EEGSEEEEEE  GSPASPAKQG  GVSRGAVPGV  LRPQEAAGKV  EKPVSQKEPT  TPYTVKLRGA  300
301   PFNVTEKNVI  EFLAPLKPVA  IRIVRNAHGN  KTGYVFVDLS  SEEEVKKALK  CNRDYMGGRY  360
361   IEVFREKQAP  TARGPPKSTT  PWQGRTLGEN  EEEEDLADSG  RLFVRNLSYT  SSEEDLEKLF  420
421   SAYGPLSELH  YPIDSLTKKP  KGFAFVTFMF  PEHAVKAYAE  VDGQVFQGRM  LHVLPSTIKK  480
481   EASQEANAPG  SSYKKKKEAM  DKANSSSSHN  WNTLFMGPNA  VADAIAQKYN  ATKSQVFDHE  540
541   TRGSVAVRVA  LGETQLVQEV  RSFLIDNGVC  LDSFSQAAAE  RSKTVILAKN  LPAGTLAAEI  600
601   QETFSRFGSL  GRVLLPEGGI  TAIVEFLEPL  EARKAFRHLA  YSKFHHVPLY  LEWAPIGVFG  660
661   AAPQKKDSQH  EQPAEKAEVE  QETVLDPEGE  KASVEGAEAS  TGKMEEEEEE  EEEEEEESIP  720
721   GCTLFIKNLN  FSTTEETLKG  VFSKVGAIKS  CTISKKKNKA  GVLLSMGFGF  VEYKKPEQAQ  780
781   KALKQLQGHT  VDGHKLEVRI  SERATKPALT  STRKKQVPKK  QTTSKILVRN  IPFQANQREI  840
841   RELFSTFGEL  KTVRLPKKMT  GTGAHRGFGF  VDFITKQDAK  KAFNALCHST  HLYGRRLVLE  900
901   WADSEVTVQT  LRRKTARHFQ  EPPKKKRSAV  LDGILEQLED  EDNSDGEQAL  QL  952
Nucleotide CDS Sequence (FASTA)
1     ATGTCGCGTC  TGATCGTGAA  GAACCTCCCG  AATGGGATGA  AGGAGGAGCG  ATTCCGGCAG  60
61    CTGTTTGCCG  CCTTTGGCAC  ACTGACCGAC  TGCAGCCTCA  AGTTCACCAA  AGACGGCAAG  120
121   TTCCGAAAGT  TCGGCTTCAT  AGGTTTCAAG  TCGGAGGAGG  AGGCCCAGGC  AGCACTGAAC  180
181   CATTTCCACC  GGAGCTTTAT  TGACACGACC  CGGATCACCG  TCGAATTCTG  CAAGTCCTTT  240
241   GGAGACCCAT  CGAAGCCCCG  AGCTTGGAGC  AAGCATGCCC  AGAAGTCAAG  TCAGCCCAAG  300
301   CAGCCGTCGC  AAGACTCCGT  TCCCTCAGAC  ACTAAAAAGG  ACAAGAAGAA  AAAAGGGCCC  360
361   AGTGACCTGG  AGAAGCTGAA  GGAAGATGCC  AAGTTCCAGG  AGTTCCTGTC  AATTCATCAG  420
421   AAGAGGACCC  AAGTGGCCAC  GTGGGCAAAC  GACGCTTTGG  AGGCCAAGCT  CCCAAAAGCA  480
481   AAAACCAAGG  CATCAAGTGA  CTATCTGAAC  TTCGACTCCG  ACTCCAACTC  TGACTCTGGG  540
541   CAGGAGAGTG  AGGAGGAGCC  AGCCAGAGAG  GACCCTGAAG  AGGAACAAGG  CCTGCAGCCA  600
601   AAGGCAGCTG  TGCAGAAGGA  GCTGTCAGAC  ATGGACTACT  TGAAATCCAA  GATGGTGCGG  660
661   GCTGAGGTGT  CCTCTGAGGA  TGAGGACGAA  GAGGACAGTG  AAGACGAGGC  GGTGAACTGT  720
721   GAAGAAGGGA  GTGAGGAAGA  GGAAGAGGAG  GGCTCCCCTG  CCTCCCCAGC  CAAGCAAGGA  780
781   GGTGTGAGCC  GGGGAGCCGT  GCCTGGGGTC  CTGAGGCCCC  AGGAAGCTGC  TGGCAAGGTA  840
841   GAGAAGCCAG  TCAGCCAGAA  GGAACCCACT  ACCCCCTACA  CCGTGAAGCT  CCGGGGAGCC  900
901   CCGTTCAATG  TCACTGAGAA  AAACGTCATT  GAATTCCTAG  CTCCTCTGAA  GCCAGTGGCC  960
961   ATCCGAATAG  TGAGAAATGC  TCACGGGAAC  AAGACAGGGT  ATGTCTTCGT  GGACCTCAGC  1020
1021  AGTGAAGAAG  AAGTAAAGAA  GGCTCTGAAG  TGCAACCGTG  ACTACATGGG  TGGACGCTAT  1080
1081  ATCGAGGTGT  TCAGGGAAAA  GCAGGCTCCC  ACCGCCCGTG  GTCCCCCAAA  GAGCACCACG  1140
1141  CCCTGGCAAG  GCCGAACGCT  CGGGGAGAAT  GAGGAGGAGG  AAGACCTGGC  CGACTCTGGG  1200
1201  AGGCTCTTCG  TACGGAACCT  GTCCTACACC  AGCTCTGAGG  AGGACCTGGA  GAAGCTTTTC  1260
1261  TCGGCCTACG  GTCCCCTGTC  AGAGCTCCAC  TACCCCATTG  ACAGCCTGAC  CAAGAAGCCG  1320
1321  AAGGGCTTTG  CCTTCGTCAC  CTTCATGTTC  CCTGAGCACG  CCGTGAAGGC  CTATGCTGAG  1380
1381  GTGGACGGGC  AGGTATTCCA  GGGCAGGATG  CTCCATGTCC  TACCTTCTAC  CATCAAGAAA  1440
1441  GAAGCCAGCC  AGGAGGCCAA  CGCCCCAGGG  TCCTCTTATA  AGAAGAAGAA  GGAAGCCATG  1500
1501  GACAAAGCCA  ACAGTTCCAG  CTCGCACAAC  TGGAACACGC  TGTTTATGGG  ACCAAATGCC  1560
1561  GTGGCTGACG  CCATTGCACA  GAAGTACAAC  GCCACCAAGA  GCCAAGTGTT  TGACCATGAG  1620
1621  ACCAGGGGCA  GCGTGGCCGT  GCGTGTGGCT  CTGGGGGAGA  CCCAGCTGGT  CCAGGAGGTC  1680
1681  CGAAGCTTCC  TTATTGACAA  TGGGGTCTGC  CTGGACTCTT  TCAGCCAGGC  TGCAGCGGAG  1740
1741  CGAAGTAAGA  CTGTGATCCT  GGCTAAGAAC  CTCCCGGCAG  GTACTCTGGC  GGCTGAGATC  1800
1801  CAGGAGACCT  TCAGCCGCTT  CGGCAGCCTG  GGTCGCGTGC  TCCTGCCTGA  AGGTGGCATC  1860
1861  ACGGCCATCG  TAGAGTTCCT  AGAGCCGCTG  GAGGCCCGCA  AGGCTTTCAG  GCACCTGGCC  1920
1921  TATTCTAAGT  TCCACCATGT  CCCCCTGTAC  CTGGAGTGGG  CTCCAATTGG  TGTCTTTGGC  1980
1981  GCAGCCCCCC  AGAAGAAAGA  TTCCCAGCAT  GAGCAGCCTG  CAGAGAAAGC  CGAGGTGGAG  2040
2041  CAGGAGACTG  TACTAGACCC  AGAAGGTGAA  AAGGCTTCGG  TAGAAGGAGC  AGAGGCCTCC  2100
2101  ACAGGCAAAA  TGGAAGAGGA  GGAGGAAGAG  GAGGAGGAGG  AGGAGGAAGA  GAGTATCCCA  2160
2161  GGATGCACTT  TGTTCATTAA  GAACCTCAAC  TTCAGCACCA  CAGAGGAGAC  ACTGAAGGGA  2220
2221  GTGTTTTCCA  AAGTGGGAGC  TATAAAGAGC  TGCACCATCT  CCAAGAAGAA  GAATAAAGCA  2280
2281  GGAGTGCTCC  TCTCAATGGG  GTTTGGGTTT  GTGGAATACA  AGAAGCCAGA  ACAGGCCCAG  2340
2341  AAAGCCCTCA  AGCAGCTCCA  GGGTCACACT  GTGGACGGCC  ATAAGCTGGA  AGTACGGATC  2400
2401  TCTGAACGGG  CCACTAAGCC  TGCCTTGACA  TCAACTCGGA  AGAAGCAGGT  CCCCAAGAAG  2460
2461  CAGACGACCT  CCAAGATCCT  GGTGCGGAAT  ATCCCCTTCC  AGGCCAACCA  GAGGGAGATC  2520
2521  CGGGAGCTTT  TCAGCACCTT  TGGGGAACTG  AAGACAGTGC  GCCTGCCGAA  GAAGATGACA  2580
2581  GGGACAGGTG  CCCACCGCGG  TTTCGGCTTT  GTGGACTTCA  TCACCAAGCA  GGATGCGAAG  2640
2641  AAAGCCTTCA  ATGCGCTGTG  TCATAGCACT  CACTTGTACG  GCCGCAGGCT  GGTTCTGGAA  2700
2701  TGGGCAGACT  CAGAGGTGAC  CGTGCAGACC  CTACGGAGGA  AGACGGCCAG  GCACTTCCAA  2760
2761  GAACCCCCGA  AGAAAAAGCG  GTCTGCAGTG  TTGGATGGGA  TCCTGGAGCA  GCTGGAAGAT  2820
2821  GAGGACAACA  GTGACGGCGA  GCAGGCTCTC  CAGCTGTGA  2859

▼ KEYWORD

ID
Family
3D-structure
Alternative splicing
Chromosome
Complete proteome
Cytoplasm
Developmental protein
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Repeat
RNA-binding
Ubl conjugation

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Chromosome
Cellular Component
Cytoplasm
Cellular Component
Nuclear speck
Cellular Component
Nucleolus
Cellular Component
Nucleoplasm
Molecular Function
RNA binding
Biological Process
MRNA cis splicing, via spliceosome
Biological Process
Multicellular organism development
Biological Process
Positive regulation of embryonic development
Biological Process
Regulation of alternative mRNA splicing, via spliceosome

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ran-0084Rattus norvegicus93.820.01612
LLPS-Mea-0949Mesocricetus auratus89.750.01521
LLPS-Pap-1019Pan paniscus81.180.01372
LLPS-Pat-0349Pan troglodytes80.970.01369
LLPS-Nol-1914Nomascus leucogenys80.870.01364
LLPS-Mam-0578Macaca mulatta80.870.01360
LLPS-Gog-2568Gorilla gorilla80.770.01364
LLPS-Maf-1513Macaca fascicularis80.770.01356
LLPS-Paa-0469Papio anubis80.750.01358
LLPS-Hos-2152Homo sapiens80.660.01361
LLPS-Eqc-0389Equus caballus80.280.01308
LLPS-Otg-0303Otolemur garnettii80.140.01163
LLPS-Cea-0987Cercocebus atys79.980.01331
LLPS-Cap-0482Cavia porcellus79.810.01336
LLPS-Caj-0622Callithrix jacchus79.50.01339
LLPS-Rhb-3036Rhinopithecus bieti79.320.01340
LLPS-Myl-3655Myotis lucifugus79.240.01356
LLPS-Aon-2775Aotus nancymaae79.190.01347
LLPS-Bot-0001Bos taurus79.050.01337
LLPS-Ova-1337Ovis aries78.770.01343
LLPS-Fud-1101Fukomys damarensis78.690.01357
LLPS-Cas-0961Carlito syrichta78.050.01133
LLPS-Caf-2201Canis familiaris77.960.01330
LLPS-Poa-2987Pongo abelii77.870.01293
LLPS-Sus-3394Sus scrofa77.750.01322
LLPS-Urm-0504Ursus maritimus77.650.01297
LLPS-Loa-0203Loxodonta africana77.610.01163
LLPS-Mal-1567Mandrillus leucophaeus77.470.01295
LLPS-Chs-1218Chlorocebus sabaeus77.010.01333
LLPS-Mup-0121Mustela putorius furo76.920.01340
LLPS-Orc-2489Oryctolagus cuniculus76.630.01293
LLPS-Fec-1763Felis catus76.470.01312
LLPS-Dio-0721Dipodomys ordii76.240.01273
LLPS-Aim-2168Ailuropoda melanoleuca75.880.01298
LLPS-Man-3569Macaca nemestrina74.870.01209
LLPS-Ora-2747Ornithorhynchus anatinus73.039e-36 142
LLPS-Mod-1471Monodelphis domestica73.020.01172
LLPS-Sah-1091Sarcophilus harrisii72.180.01207
LLPS-Ten-0736Tetraodon nigroviridis66.165e-140 428
LLPS-Pes-1542Pelodiscus sinensis64.260.0 984
LLPS-Anc-0058Anolis carolinensis64.130.01105
LLPS-Tag-0521Taeniopygia guttata63.950.01069
LLPS-Fia-2644Ficedula albicollis63.720.01021
LLPS-Anp-2292Anas platyrhynchos62.360.0 921
LLPS-Gaga-0584Gallus gallus62.240.01024
LLPS-Leo-3410Lepisosteus oculatus61.530.01014
LLPS-Xet-1669Xenopus tropicalis61.320.01031
LLPS-Lac-0325Latimeria chalumnae61.10.0 609
LLPS-Asm-2980Astyanax mexicanus60.740.0 699
LLPS-Orn-0301Oreochromis niloticus59.790.0 977
LLPS-Scm-1219Scophthalmus maximus59.540.0 975
LLPS-Meg-0157Meleagris gallopavo59.331e-42 172
LLPS-Gaa-0342Gasterosteus aculeatus58.790.0 923
LLPS-Dar-1974Danio rerio57.850.0 928
LLPS-Orl-1270Oryzias latipes57.680.0 950
LLPS-Pof-0087Poecilia formosa57.40.0 919
LLPS-Icp-0000Ictalurus punctatus57.250.0 948
LLPS-Tar-1472Takifugu rubripes57.090.0 906
LLPS-Scf-2647Scleropages formosus56.510.0 966
LLPS-Xim-1125Xiphophorus maculatus56.340.0 936
LLPS-Usm-0709Ustilago maydis51.221e-1070.1
LLPS-Spr-0077Sporisorium reilianum50.04e-1068.2
LLPS-Cii-0089Ciona intestinalis49.920.0 627
LLPS-Cae-0978Caenorhabditis elegans48.861e-1173.2
LLPS-Bro-1414Brassica oleracea44.942e-1172.4
LLPS-Brn-2660Brassica napus44.329e-1170.5
LLPS-Brr-1824Brassica rapa44.322e-1069.3
LLPS-Coc-0935Corchorus capsularis44.231e-59 219
LLPS-Chc-0211Chondrus crispus43.821e-0759.7
LLPS-Abg-0800Absidia glauca43.426e-138 439
LLPS-Osl-0161Ostreococcus lucimarinus43.185e-1067.8
LLPS-Via-0022Vigna angularis42.374e-21 103
LLPS-Php-0326Physcomitrella patens42.148e-1686.7
LLPS-Cus-0898Cucumis sativus41.671e-1379.3
LLPS-Sol-0929Solanum lycopersicum41.256e-114 377
LLPS-Sot-0200Solanum tuberosum41.166e-114 377
LLPS-Sem-2068Selaginella moellendorffii40.862e-116 380
LLPS-Gas-0771Galdieria sulphuraria40.61e-91 313
LLPS-Gor-1673Gossypium raimondii40.553e-122 399
LLPS-Mae-0749Manihot esculenta40.186e-112 371
LLPS-Hov-1199Hordeum vulgare40.132e-1585.5
LLPS-Tra-0799Triticum aestivum40.132e-1585.5
LLPS-Viv-0479Vitis vinifera39.863e-117 385
LLPS-Mua-0631Musa acuminata39.761e-1482.8
LLPS-Orm-0909Oryza meridionalis39.626e-1480.9
LLPS-Scc-1402Schizosaccharomyces cryophilus39.614e-105 352
LLPS-Nia-1442Nicotiana attenuata39.61e-111 370
LLPS-Tru-0396Triticum urartu39.499e-1686.7
LLPS-Prp-0171Prunus persica39.355e-1584.0
LLPS-Scj-0240Schizosaccharomyces japonicus39.344e-110 365
LLPS-Asfu-0217Aspergillus fumigatus39.155e-98 333
LLPS-Art-0344Arabidopsis thaliana39.072e-1275.5
LLPS-Amt-0084Amborella trichopoda38.995e-118 383
LLPS-Nef-0633Neosartorya fischeri38.953e-97 331
LLPS-Asn-0516Aspergillus nidulans38.921e-95 327
LLPS-Orb-2066Oryza barthii38.83e-94 325
LLPS-Orni-0774Oryza nivara38.627e-96 325
LLPS-Org-1002Oryza glaberrima38.623e-94 324
LLPS-Pot-0117Populus trichocarpa38.583e-109 364
LLPS-Thc-1269Theobroma cacao38.57e-112 374
LLPS-Orgl-0729Oryza glumaepatula38.437e-94 323
LLPS-Met-0541Medicago truncatula38.413e-1481.6
LLPS-Asg-0072Ashbya gossypii38.396e-94 322
LLPS-Scs-0197Sclerotinia sclerotiorum38.397e-103 347
LLPS-Ori-0106Oryza indica38.362e-1482.4
LLPS-Orr-0364Oryza rufipogon38.362e-1482.4
LLPS-Scp-0429Schizosaccharomyces pombe38.166e-102 344
LLPS-Sac-0956Saccharomyces cerevisiae38.062e-96 330
LLPS-Asni-0870Aspergillus niger38.07e-100 338
LLPS-Hea-0391Helianthus annuus37.983e-109 365
LLPS-Kop-0702Komagataella pastoris37.923e-101 342
LLPS-Phv-0702Phaseolus vulgaris37.881e-105 354
LLPS-Drm-1236Drosophila melanogaster37.831e-167 521
LLPS-Trv-0553Trichoderma virens37.825e-92 317
LLPS-Asc-0312Aspergillus clavatus37.783e-97 331
LLPS-Mao-0428Magnaporthe oryzae37.621e-92 319
LLPS-Dac-0550Daucus carota37.61e-108 361
LLPS-Cogr-0030Colletotrichum graminicola37.553e-97 332
LLPS-Glm-0481Glycine max37.52e-1069.3
LLPS-Ast-0306Aspergillus terreus37.451e-95 326
LLPS-Asf-0781Aspergillus flavus37.432e-94 323
LLPS-Aso-0316Aspergillus oryzae37.431e-94 324
LLPS-Miv-0790Microbotryum violaceum37.274e-100 338
LLPS-Yal-1020Yarrowia lipolytica37.24e-97 331
LLPS-Map-0425Magnaporthe poae37.158e-88 305
LLPS-Zem-0638Zea mays37.151e-96 330
LLPS-Sob-1803Sorghum bicolor37.152e-99 338
LLPS-Vir-1195Vigna radiata37.033e-104 350
LLPS-Pyt-0273Pyrenophora teres36.922e-98 334
LLPS-Sei-0085Setaria italica36.916e-92 318
LLPS-Brd-0610Brachypodium distachyon36.881e-95 328
LLPS-Phn-0114Phaeosphaeria nodorum36.873e-98 334
LLPS-Ved-0277Verticillium dahliae36.843e-89 310
LLPS-Lep-1009Leersia perrieri36.774e-96 332
LLPS-Chr-0460Chlamydomonas reinhardtii36.761e-102 351
LLPS-Crn-0049Cryptococcus neoformans36.741e-96 327
LLPS-Fuo-0827Fusarium oxysporum36.77e-92 317
LLPS-Ors-1600Oryza sativa36.615e-97 322
LLPS-Fus-0184Fusarium solani36.51e-92 319
LLPS-Put-0307Puccinia triticina36.431e-98 336
LLPS-Cog-0801Colletotrichum gloeosporioides36.46e-86 301
LLPS-Dos-0707Dothistroma septosporum36.361e-92 318
LLPS-Pytr-0776Pyrenophora triticirepentis36.352e-94 323
LLPS-Lem-0831Leptosphaeria maculans36.339e-100 338
LLPS-Orbr-0275Oryza brachyantha36.333e-90 313
LLPS-Nec-0079Neurospora crassa36.248e-89 308
LLPS-Tum-0282Tuber melanosporum36.153e-87 302
LLPS-Fuv-0408Fusarium verticillioides36.092e-92 319
LLPS-Arl-0344Arabidopsis lyrata35.981e-102 345
LLPS-Trr-1090Trichoderma reesei35.841e-89 309
LLPS-Blg-0455Blumeria graminis35.756e-95 325
LLPS-Coo-0197Colletotrichum orbiculare35.742e-92 318
LLPS-Gag-0223Gaeumannomyces graminis35.672e-90 313
LLPS-Zyt-0733Zymoseptoria tritici35.621e-91 314
LLPS-Beb-0382Beauveria bassiana35.382e-93 321
LLPS-Pug-0219Puccinia graminis34.556e-94 320
LLPS-Orp-0175Oryza punctata34.311e-71 256
LLPS-Mel-1077Melampsora laricipopulina33.464e-91 305
LLPS-Ict-2847Ictidomys tridecemlineatus32.545e-1582.0
LLPS-Cym-0299Cyanidioschyzon merolae30.644e-75 269